Strain Name:
C57BL/6J-MtgxR4963Btlr/Mmmh
Stock Number:
042560-MU
Citation ID:
RRID:MMRRC_042560-MU
Other Names:
R4963 (G1), C57BL/6J-MtgxR4963Btlr
Major Collection:

Gene Information

Dnajc3
Name: DnaJ heat shock protein family (Hsp40) member C3
Synonyms: Dnajc3, Prkri, Dnajc3a, Dnajc3b, p58IPK, mp58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 100037258
VEGA: 14
HGNC: HGNC:9439
Homologene: 2486
Ptprz1
Name: protein tyrosine phosphatase, receptor type Z, polypeptide 1
Synonyms: PTPbeta, DSD-1-PG, Ptprz, Ptpz, Rptpbeta, PTPzeta, RPTPz, phosphacan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Ank2
Name: ankyrin 2, brain
Synonyms: Ankyrin-2, Gm4392, Ank-2, ankyrin B, Ankyrin-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 109676
HGNC: HGNC:493
Ptpn12
Name: protein tyrosine phosphatase, non-receptor type 12
Synonyms: PTP-PEST, P19-PTP, PTP-P19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19248
HGNC: HGNC:9645
Homologene: 37691
Smc2
Name: structural maintenance of chromosomes 2
Synonyms: CAP-E, 5730502P04Rik, Smc2l1, Fin16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 14211
Homologene: 4705
Smarcc1
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
Synonyms: BAF155, msp3, SRG3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20588
Homologene: 68296
Tpp2
Name: tripeptidyl peptidase II
Synonyms: TppII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22019
Homologene: 2471
Gtpbp4
Name: GTP binding protein 4
Synonyms: Crfg, Nog1, 2610028C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 69237
VEGA: 13
Homologene: 7100
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, D4Abb1e, 4833432B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100019
Homologene: 39689
Abcg5
Name: ATP binding cassette subfamily G member 5
Synonyms: Sterolin-1, trac, cmp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 27409
Homologene: 31909
Topbp1
Name: topoisomerase (DNA) II binding protein 1
Synonyms: D430026L04Rik, 1110031N14Rik, 2810429C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235559
Homologene: 38262
Nedd1
Name: neural precursor cell expressed, developmentally down-regulated gene 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 17997
VEGA: 10
HGNC: HGNC:7723
Homologene: 7439
Zfp442
Name: zinc finger protein 442
Synonyms: OTTMUSG00000015730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 668923
Homologene: 136215
Pex1
Name: peroxisomal biogenesis factor 1
Synonyms: peroxisome biogenesis factor 1, 5430414H02Rik, E330005K07Rik, ZWS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71382
HGNC: HGNC:8850
Homologene: 27006
Anapc7
Name: anaphase promoting complex subunit 7
Synonyms: APC7, prediabetic NOD sera-reactive autoantigen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56317
Homologene: 10512
Rxfp3
Name: relaxin family peptide receptor 3
Synonyms: Salpr, Rln3r1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239336
Homologene: 9568
Dsp
Name: desmoplakin
Synonyms: 5730453H04Rik, DP, 2300002E22Rik, rul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Arhgap17
Name: Rho GTPase activating protein 17
Synonyms: Nadrin2, WBP15, Nadrin, 5730403H17Rik, Rich1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 70497
Homologene: 9984
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: Sema6A-1, sema, A730020P05Rik, VIa, Semaq
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 20358
Homologene: 32426
Hgfac
Name: hepatocyte growth factor activator
Synonyms: HGFA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54426
HGNC: HGNC:4894
Homologene: 1170
Enpp6
Name: ectonucleotide pyrophosphatase/phosphodiesterase 6
Synonyms: 4833421B01Rik, Npp6, D8Ertd514e, B830047L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 320981
Homologene: 62657
Kirrel2
Name: kirre like nephrin family adhesion molecule 2
Synonyms: NEPH3, C330019F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243911
Homologene: 35249
Rdh11
Name: retinol dehydrogenase 11
Synonyms: Psdr1, Mdt1, 2610319N22Rik, Arsdr1, M42C60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 17252
Homologene: 100724
Dgke
Name: diacylglycerol kinase, epsilon
Synonyms: DAGK6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 56077
HGNC: HGNC:2852
Homologene: 2705
Uqcrfs1
Name: ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
Synonyms: 4430402G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66694
Homologene: 4378
Palld
Name: palladin, cytoskeletal associated protein
Synonyms: 2410003B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 72333
Homologene: 75052
Rbm19
Name: RNA binding motif protein 19
Synonyms: 1200009A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74111
Homologene: 7158
Prmt9
Name: protein arginine methyltransferase 9
Synonyms: Prmt10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 102182
Homologene: 16298
Nle1
Name: notchless homolog 1
Synonyms: l11Jus1, Nle, notchless, l11Jus4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217011
Homologene: 5494
Ldb3
Name: LIM domain binding 3
Synonyms: cypher, ZASP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 24131
VEGA: 14
Homologene: 134626
Mlph
Name: melanophilin
Synonyms: D1Wsu84e, Slac-2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 171531
Homologene: 11465
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Kif27
Name: kinesin family member 27
Synonyms: 4930517I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 75050
VEGA: 13
Homologene: 69235
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 26875
Homologene: 69111
Atp1a3
Name: ATPase, Na+/K+ transporting, alpha 3 polypeptide
Synonyms: Atpa-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232975
HGNC: HGNC:801
Homologene: 113729
Srgap3
Name: SLIT-ROBO Rho GTPase activating protein 3
Synonyms: Arhgap14, D130026O08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 259302
Homologene: 56686
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: PKHDL1, fibrocystin L, D86 mRNA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 192190
Homologene: 16332
Lcn5
Name: lipocalin 5
Synonyms: MEP10, Erabp, mE-RABP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 13863
Homologene: 7305
Npy4r
Name: neuropeptide Y receptor Y4
Synonyms: Y4, NYYR-D, Ppyr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19065
VEGA: 14
HGNC: HGNC:9329
Homologene: 38119
Glp2r
Name: glucagon-like peptide 2 receptor
Synonyms: GLP-2, 9530092J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 93896
HGNC: HGNC:4325
Homologene: 3132
Cyp2j11
Name: cytochrome P450, family 2, subfamily j, polypeptide 11
Synonyms: Cyp2j11-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100066
Homologene: 133819
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Vwf
Name: Von Willebrand factor
Synonyms: B130011O06Rik, 6820430P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 22371
Homologene: 466
Abca15
Name: ATP-binding cassette, sub-family A (ABC1), member 15
Synonyms: 4930500I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 320631
Homologene: 87255
Mtpap
Name: mitochondrial poly(A) polymerase
Synonyms: 0610027A18Rik, Papd1, Tent6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 67440
VEGA: 18
Homologene: 10008
Kcnh4
Name: potassium voltage-gated channel, subfamily H (eag-related), member 4
Synonyms: BEC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380728
HGNC: HGNC:6253
Homologene: 8180
Slco1a1
Name: solute carrier organic anion transporter family, member 1a1
Synonyms: Slc21a1, Oatp1, Oatp1a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 28248
Homologene: 137261
Tulp4
Name: tubby like protein 4
Synonyms: 1110057P05Rik, 2210038L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 68842
Homologene: 32467
Gsdmc
Name: gasdermin C
Synonyms: Gsdmc1, Mlze
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 83492
HGNC: HGNC:7151
Homologene: 69487
Ninl
Name: ninein-like
Synonyms: LOC381388, LOC381387, 4930519N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 78177
Homologene: 57024
Cep89
Name: centrosomal protein 89
Synonyms: Ccdc123, 2610507L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72140
Homologene: 12444
Wdhd1
Name: WD repeat and HMG-box DNA binding protein 1
Synonyms: D630024B06Rik, AND-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 218973
Homologene: 56019
Slc5a1
Name: solute carrier family 5 (sodium/glucose cotransporter), member 1
Synonyms: sodium glucose cotransporter 1, Sglt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20537
Homologene: 55456
Dcbld2
Name: discoidin, CUB and LCCL domain containing 2
Synonyms: 1700055P21Rik, Esdn, CLCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 73379
Homologene: 12499
H2-M1
Name: histocompatibility 2, M region locus 1
Synonyms: H-2M1, Mb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224756
Homologene: 110792
A530064D06Rik
Name: RIKEN cDNA A530064D06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 328830
VEGA: 17
Homologene: 136361
Obsl1
Name: obscurin-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98733
Vmn2r107
Name: vomeronasal 2, receptor 107
Synonyms: V2r6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 22312
Homologene: 129750
Evc
Name: EvC ciliary complex subunit 1
Synonyms: Ellis van Creveld gene syndrome
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 59056
HGNC: HGNC:3497
Homologene: 10949
Spata18
Name: spermatogenesis associated 18
Synonyms: 1700067I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 73472
Homologene: 17057
Polrmt
Name: polymerase (RNA) mitochondrial (DNA directed)
Synonyms: 1110018N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216151
HGNC: HGNC:9200
Homologene: 37996
Zfp709
Name: zinc finger protein 709
Synonyms: GIOT-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 236193
Homologene: 136795
Mfrp
Name: membrane frizzled-related protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 259172
Homologene: 12866
Msi1
Name: musashi RNA-binding protein 1
Synonyms: m-Msi-1, Msi1, Msi1h, Musahi1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 17690
HGNC: HGNC:7330
Homologene: 55657
Smyd4
Name: SET and MYND domain containing 4
Synonyms: G430029E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 319822
Homologene: 35098
Nkx3-1
Name: NK3 homeobox 1
Synonyms: NKX3.1, Bax, Nkx-3.1, NKX3A, bagpipe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 18095
HGNC: HGNC:7838
Homologene: 4494
Olfr1366
Name: olfactory receptor 1366
Synonyms: MOR130-2, GA_x6K02T2QHY8-11707053-11707994
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 258280
Homologene: 105872
Fam98a
Name: family with sequence similarity 98, member A
Synonyms: 2810405J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 72722
Homologene: 41042
Zswim2
Name: zinc finger SWIM-type containing 2
Synonyms: MEX, 1700025P14Rik, 4933437F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71861
Homologene: 32689
Slc17a2
Name: solute carrier family 17 (sodium phosphate), member 2
Synonyms: NPT3, C730032N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218103
Homologene: 4260
Irx2
Name: Iroquois homeobox 2
Synonyms: IRX6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 16372
Homologene: 56490
Smyd2
Name: SET and MYND domain containing 2
Synonyms: 1110020E07Rik, KMT3C, Zmynd14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226830
Homologene: 32466
Terb1
Name: telomere repeat binding bouquet formation protein 1
Synonyms: Ccdc79, 4930532D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 320022
Homologene: 18330
March8
Name: membrane-associated ring finger (C3HC4) 8
Synonyms: Mir, 1300017E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 71779
Homologene: 12412
Amy2b
Name: amylase 2b
Synonyms: mAmy2-1, Amy2-2, Amy-X
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 545562
Mtmr11
Name: myotubularin related protein 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 194126
Homologene: 82382
Gm15293
Name: predicted gene 15293
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 100041759
Homologene: 113382
Timd2
Name: T cell immunoglobulin and mucin domain containing 2
Synonyms: TIM-2, Tim2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 171284
Homologene: 82236
Rps13-ps1
Name: ribosomal protein S13, pseudogene 1
Synonyms: Gm6573
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 625298
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 43,992,268 bp
  • G to T, chromosome 1 at 75,505,627 bp
  • A to G, chromosome 1 at 90,939,390 bp
  • A to T, chromosome 1 at 189,882,188 bp
  • A to G, chromosome 2 at 25,661,414 bp
  • A to G, chromosome 2 at 76,753,945 bp
  • A to T, chromosome 2 at 83,925,110 bp
  • A to T, chromosome 2 at 150,408,495 bp
  • A to G, chromosome 2 at 150,939,909 bp
  • T to C, chromosome 3 at 96,163,250 bp
  • T to A, chromosome 3 at 113,153,441 bp
  • G to A, chromosome 3 at 127,032,096 bp
  • C to A, chromosome 4 at 32,756,512 bp
  • T to C, chromosome 4 at 52,450,826 bp
  • T to C, chromosome 4 at 96,316,382 bp
  • T to A, chromosome 5 at 3,609,924 bp
  • T to C, chromosome 5 at 14,669,221 bp
  • T to A, chromosome 5 at 21,015,708 bp
  • C to T, chromosome 5 at 33,160,782 bp
  • T to C, chromosome 5 at 35,047,255 bp
  • C to T, chromosome 5 at 37,322,049 bp
  • T to A, chromosome 5 at 73,678,993 bp
  • T to A, chromosome 5 at 115,450,885 bp
  • T to A, chromosome 5 at 120,141,566 bp
  • T to A, chromosome 5 at 122,422,606 bp
  • G to A, chromosome 6 at 23,049,584 bp
  • C to T, chromosome 6 at 112,816,732 bp
  • G to A, chromosome 6 at 116,386,271 bp
  • C to T, chromosome 6 at 125,667,483 bp
  • A to G, chromosome 6 at 141,923,099 bp
  • T to C, chromosome 7 at 24,994,626 bp
  • C to A, chromosome 7 at 30,450,801 bp
  • T to G, chromosome 7 at 35,403,152 bp
  • T to C, chromosome 7 at 120,360,919 bp
  • T to C, chromosome 7 at 123,308,360 bp
  • C to T, chromosome 8 at 21,201,758 bp
  • A to G, chromosome 8 at 47,065,461 bp
  • C to T, chromosome 8 at 61,703,210 bp
  • A to G, chromosome 8 at 71,889,788 bp
  • A to G, chromosome 8 at 77,555,729 bp
  • T to A, chromosome 8 at 87,048,006 bp
  • A to G, chromosome 8 at 104,482,318 bp
  • A to T, chromosome 9 at 44,103,264 bp
  • C to A, chromosome 9 at 103,320,605 bp
  • T to A, chromosome 9 at 110,213,745 bp
  • A to G, chromosome 10 at 79,746,551 bp
  • C to A, chromosome 10 at 92,695,031 bp
  • T to C, chromosome 11 at 46,682,790 bp
  • T to C, chromosome 11 at 66,084,611 bp
  • G to T, chromosome 11 at 67,757,593 bp
  • C to T, chromosome 11 at 75,382,294 bp
  • A to G, chromosome 11 at 82,904,937 bp
  • A to G, chromosome 11 at 89,050,802 bp
  • C to A, chromosome 11 at 100,752,253 bp
  • A to G, chromosome 12 at 79,188,606 bp
  • C to A, chromosome 13 at 8,985,217 bp
  • A to G, chromosome 13 at 21,537,982 bp
  • A to G, chromosome 13 at 23,819,407 bp
  • A to T, chromosome 13 at 30,540,763 bp
  • A to G, chromosome 13 at 38,197,870 bp
  • T to C, chromosome 13 at 58,328,994 bp
  • T to C, chromosome 13 at 72,632,610 bp
  • T to A, chromosome 14 at 34,147,016 bp
  • T to G, chromosome 14 at 34,566,858 bp
  • A to G, chromosome 14 at 47,268,689 bp
  • G to A, chromosome 14 at 69,190,918 bp
  • C to A, chromosome 14 at 118,978,173 bp
  • A to G, chromosome 15 at 11,036,281 bp
  • G to A, chromosome 15 at 44,504,025 bp
  • A to G, chromosome 15 at 63,804,380 bp
  • T to C, chromosome 16 at 58,465,782 bp
  • G to A, chromosome 17 at 6,198,813 bp
  • A to T, chromosome 17 at 20,375,141 bp
  • A to G, chromosome 17 at 36,671,738 bp
  • A to T, chromosome 17 at 48,163,414 bp
  • A to G, chromosome 17 at 75,538,982 bp
  • G to T, chromosome 17 at 84,660,141 bp
  • T to C, chromosome 18 at 4,375,638 bp
  • T to C, chromosome 18 at 47,298,251 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4963 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042560-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.