Strain Name:
C57BL/6J-MtgxR5049Btlr/Mmmh
Stock Number:
042639-MU
Citation ID:
RRID:MMRRC_042639-MU
Other Names:
R5049 (G1), C57BL/6J-MtgxR5049Btlr
Major Collection:

Gene Information

Sp4
Name: trans-acting transcription factor 4
Synonyms: 5730497N03Rik, HF-1b, HF1-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20688
VEGA: 12
Homologene: 2341
Kif5a
Name: kinesin family member 5A
Synonyms: Kif5, Kns, D10Bwg0738e, Khc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16572
VEGA: 10
HGNC: HGNC:6323
Homologene: 55861
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Herc3
Name: hect domain and RLD 3
Synonyms: 5730409F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 73998
HGNC: HGNC:4876
Homologene: 57095
Tbx21
Name: T-box 21
Synonyms: TBT1, Tbet, Tblym, T-bet
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 57765
Homologene: 8353
Epb41l1
Name: erythrocyte membrane protein band 4.1 like 1
Synonyms: 4.1N, Epb4.1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13821
HGNC: HGNC:3378
Homologene: 8126
Zfp101
Name: zinc finger protein 101
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22643
Homologene: 137226
Map4
Name: microtubule-associated protein 4
Synonyms: Mtap4, MAP 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17758
HGNC: HGNC:6862
Homologene: 1780
Gcn1
Name: GCN1 activator of EIF2AK4
Synonyms: Gcn1l1, G431004K08Rik, GCN1L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231659
HGNC: HGNC:4199
Homologene: 5887
Tpp2
Name: tripeptidyl peptidase II
Synonyms: TppII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22019
Homologene: 2471
Sdad1
Name: SDA1 domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231452
Homologene: 6036
Trrap
Name: transformation/transcription domain-associated protein
Synonyms: transactivation/transformation-domain associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100683
Homologene: 39246
Uqcc1
Name: ubiquinol-cytochrome c reductase complex assembly factor 1
Synonyms: Uqcc, 2310079L17Rik, Bfzp, Cbp3, 3110038N19Rik, mbFZb, 2410003P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56046
Homologene: 14709
Zfp619
Name: zinc finger protein 619
Synonyms: 3000002G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70227
Homologene: 133818
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: FSA, Tweek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229227
Homologene: 52105
Pdcd11
Name: programmed cell death 11
Synonyms: ALG-4, 1110021I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18572
VEGA: 19
Homologene: 74968
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 21819
Homologene: 2430
Parp4
Name: poly (ADP-ribose) polymerase family, member 4
Synonyms: Adprtl1, C030027K23Rik, E230037B21Rik, PH5P, p193, VAULT3, VPARP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 328417
HGNC: HGNC:271
Homologene: 124423
Sprn
Name: shadow of prion protein
Synonyms: shadoo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212518
Homologene: 84643
Socs7
Name: suppressor of cytokine signaling 7
Synonyms: 2310063P06Rik, Nap4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192157
Homologene: 16331
Tmem245
Name: transmembrane protein 245
Synonyms: A630051L19Rik, D730040F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242474
HGNC: HGNC:1363
Homologene: 41841
Ufl1
Name: UFM1 specific ligase 1
Synonyms: Maxer, 1810074P20Rik, Rcad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67490
Homologene: 9093
Golga1
Name: golgi autoantigen, golgin subfamily a, 1
Synonyms: golgin-97, awag, Golgi97, 2210418B03Rik, 0710001G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76899
HGNC: HGNC:4424
Homologene: 68223
Puf60
Name: poly-U binding splicing factor 60
Synonyms: 2810454F19Rik, 2410104I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67959
VEGA: 15
Homologene: 8614
Tasor2
Name: transcription activation suppressor family member 2
Synonyms: Fam208b, BC016423
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105203
VEGA: 13
Homologene: 26435
Tfrc
Name: transferrin receptor
Synonyms: 2610028K12Rik, TfR1, E430033M20Rik, Mtvr1, p90, CD71, Mtvr-1, Trfr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22042
Homologene: 2429
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230895
Homologene: 15583
Zswim6
Name: zinc finger SWIM-type containing 6
Synonyms: 2900036G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67263
VEGA: 13
Homologene: 83517
Aamp
Name: angio-associated migratory protein
Synonyms: Aamp-rs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227290
HGNC: HGNC:18
Homologene: 846
Tnc
Name: tenascin C
Synonyms: tenascin-C, Hxb, hexabrachion, TN, C130033P17Rik, cytotactin, TN-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21923
HGNC: HGNC:5318
Homologene: 55636
Angptl7
Name: angiopoietin-like 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 654812
Homologene: 133923
Lctl
Name: lactase-like
Synonyms: KLPH, E130104I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235435
Homologene: 70710
Zfy1
Name: zinc finger protein 1, Y-linked
Synonyms: Zfy-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 22767
Homologene: 56456
Extl3
Name: exostosin-like glycosyltransferase 3
Synonyms: 2900009G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 54616
VEGA: 14
HGNC: HGNC:3518
Homologene: 1103
1810013L24Rik
Name: RIKEN cDNA 1810013L24 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 69053
VEGA: 16
Homologene: 105712
Sh3bp5l
Name: SH3 binding domain protein 5 like
Synonyms: 2310074E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 79566
Homologene: 32584
Ccl2
Name: chemokine (C-C motif) ligand 2
Synonyms: Sigje, MCP-1, Scya2, monocyte chemotactic protein, monocyte chemoattractant protein-1, MCP1, HC11, SMC-CF, MCAF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20296
Homologene: 2241
Tmem86b
Name: transmembrane protein 86B
Synonyms: C330014O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68255
Homologene: 52159
Tnfaip2
Name: tumor necrosis factor, alpha-induced protein 2
Synonyms: Tnfip2, Exoc3l3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 21928
Homologene: 4583
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: Dnhd3, 2900022L05Rik, Dnahc2, D330014H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Mrpl30
Name: mitochondrial ribosomal protein L30
Synonyms: Rpml28, 2310001L22Rik, MRP-L28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 107734
Homologene: 32675
Prss32
Name: protease, serine 32
Synonyms: 2010001P08Rik, tryptase-5, mT5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 69814
Homologene: 84859
Gamt
Name: guanidinoacetate methyltransferase
Synonyms: Spintz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14431
HGNC: HGNC:4136
Homologene: 32089
Fam160b1
Name: family with sequence similarity 160, member B1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226252
VEGA: 19
Homologene: 28133
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: LOC380889, Hdhc3, HL-19, DLP12, HL19, DHC3, 4921531P07Rik, Dnahc12, Dnahc7l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: PKHDL1, D86 mRNA, fibrocystin L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 192190
Homologene: 16332
Lama3
Name: laminin, alpha 3
Synonyms: nicein, 150kDa, [a]3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 545030
Homologene: 83473
Xirp2
Name: xin actin-binding repeat containing 2
Synonyms: 2310008C07Rik, mXin beta, myomaxin, Cmya3, A530024P18Rik, 2310003D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241431
Homologene: 19388
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Tnn
Name: tenascin N
Synonyms: tenascin-W, Tnw
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329278
Homologene: 18634
Prss45
Name: protease, serine 45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 260408
Homologene: 51905
Slc3a1
Name: solute carrier family 3, member 1
Synonyms: NTAA, D2H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20532
VEGA: 17
Homologene: 37289
Pard3b
Name: par-3 family cell polarity regulator beta
Synonyms: 1810008K04Rik, 2010002N16Rik, 2810455B10Rik, PAR3L, Als2cr19, PAR3beta, PAR3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72823
Homologene: 35389
Slc8a3
Name: solute carrier family 8 (sodium/calcium exchanger), member 3
Synonyms: Ncx3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 110893
Homologene: 62645
9330182L06Rik
Name: RIKEN cDNA 9330182L06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231014
Homologene: 27396
Trim75
Name: tripartite motif-containing 75
Synonyms: LOC333307
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 333307
Homologene: 53452
Trav7-6
Name: T cell receptor alpha variable 7-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 213480
Mapkbp1
Name: mitogen-activated protein kinase binding protein 1
Synonyms: Jnkbp1, 2810483F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26390
Homologene: 69109
Vmn1r185
Name: vomeronasal 1 receptor 185
Synonyms: V1re12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 171265
Homologene: 74353
Atxn7l1
Name: ataxin 7-like 1
Synonyms: 2810423G08Rik, Atxn7l4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 380753
Homologene: 53366
Vmn1r184
Name: vomeronasal 1 receptor, 184
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100312477
Homologene: 74353
Idi1
Name: isopentenyl-diphosphate delta isomerase
Synonyms: 4832416K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319554
HGNC: HGNC:5387
Homologene: 3315
Vmn2r4
Name: vomeronasal 2, receptor 4
Synonyms: EG637053
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 637053
Homologene: 129754
Lrriq4
Name: leucine-rich repeats and IQ motif containing 4
Synonyms: 4930558O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68307
Homologene: 12260
Tas2r131
Name: taste receptor, type 2, member 131
Synonyms: Tas2r31, T2R31, mGR31, mt2r61
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387356
Homologene: 52298
Vmn2r87
Name: vomeronasal 2, receptor 87
Synonyms: EG625131
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 625131
Homologene: 129606
Kcnq3
Name: potassium voltage-gated channel, subfamily Q, member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110862
HGNC: HGNC:6297
Homologene: 20949
Sorcs3
Name: sortilin-related VPS10 domain containing receptor 3
Synonyms: 6330404A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66673
VEGA: 19
Homologene: 8986
Ifit1bl1
Name: interferon induced protein with tetratricpeptide repeats 1B like 1
Synonyms: Gm14446
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 667373
Homologene: 78213
Cbr4
Name: carbonyl reductase 4
Synonyms: A730083J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234309
Homologene: 57181
Foxf2
Name: forkhead box F2
Synonyms: Fkh20, LUN, FREAC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14238
HGNC: HGNC:3810
Homologene: 1115
Olfr1122
Name: olfactory receptor 1122
Synonyms: GA_x6K02T2Q125-48880078-48881058, MOR264-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259033
Homologene: 73977
Olfr71
Name: olfactory receptor 71
Synonyms: GA_x6K02T2N78B-16230286-16231224, MOR262-4, mOR17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56015
Homologene: 10460
Acot8
Name: acyl-CoA thioesterase 8
Synonyms: Pte1, PTE-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 170789
Homologene: 3991
Gm21738
Name: predicted gene, 21738
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
C130026L21Rik
Name: RIKEN cDNA C130026L21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330164
Ccl19
Name: chemokine (C-C motif) ligand 19
Synonyms: exodus-3, CKb11, Scya19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 24047
Homologene: 4569
Hes2
Name: hes family bHLH transcription factor 2
Synonyms: HES-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15206
Homologene: 22455
Mir7578
Name: microRNA 7578
Synonyms: Gm27789, mmu-miR-7578, mmu-mir-7578
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 102466836
VEGA: 2
Hopxos
Name: HOP homeobox, opposite strand
Synonyms: Gm15830
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 102637820
Ighv7-3
Name: immunoglobulin heavy variable 7-3
Synonyms: Gm16842
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 629822
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 37,897,710 bp
  • T to C, chromosome 1 at 44,001,473 bp
  • T to A, chromosome 1 at 62,161,161 bp
  • A to G, chromosome 1 at 74,282,539 bp
  • T to A, chromosome 1 at 160,140,738 bp
  • G to T, chromosome 2 at 27,450,577 bp
  • A to T, chromosome 2 at 39,047,735 bp
  • A to G, chromosome 2 at 67,517,134 bp
  • A to T, chromosome 2 at 87,388,658 bp
  • A to T, chromosome 2 at 112,640,171 bp
  • G to T, chromosome 2 at 120,015,501 bp
  • A to G, chromosome 2 at 155,910,421 bp
  • C to A, chromosome 2 at 156,524,939 bp
  • A to G, chromosome 2 at 164,799,690 bp
  • T to A, chromosome 3 at 30,650,937 bp
  • T to A, chromosome 3 at 37,040,506 bp
  • T to C, chromosome 3 at 37,041,390 bp
  • A to C, chromosome 3 at 64,398,598 bp
  • G to T, chromosome 4 at 25,254,773 bp
  • A to G, chromosome 4 at 42,756,268 bp
  • A to T, chromosome 4 at 43,706,259 bp
  • A to G, chromosome 4 at 56,925,057 bp
  • A to G, chromosome 4 at 64,017,986 bp
  • A to T, chromosome 4 at 145,086,766 bp
  • A to G, chromosome 4 at 148,498,011 bp
  • C to A, chromosome 4 at 152,159,874 bp
  • A to G, chromosome 5 at 9,428,488 bp
  • C to A, chromosome 5 at 77,095,052 bp
  • T to C, chromosome 5 at 92,303,977 bp
  • T to A, chromosome 5 at 111,581,836 bp
  • T to A, chromosome 5 at 115,606,671 bp
  • T to A, chromosome 5 at 144,826,717 bp
  • A to G, chromosome 6 at 58,894,539 bp
  • T to C, chromosome 6 at 132,957,577 bp
  • G to A, chromosome 7 at 4,628,466 bp
  • A to G, chromosome 7 at 26,267,368 bp
  • A to G, chromosome 7 at 26,611,495 bp
  • G to A, chromosome 7 at 39,535,514 bp
  • C to A, chromosome 7 at 140,153,478 bp
  • T to G, chromosome 8 at 61,495,204 bp
  • T to C, chromosome 8 at 64,982,439 bp
  • T to C, chromosome 9 at 64,122,352 bp
  • T to A, chromosome 9 at 110,079,814 bp
  • A to G, chromosome 9 at 110,840,470 bp
  • T to A, chromosome 10 at 80,258,954 bp
  • T to C, chromosome 10 at 127,239,839 bp
  • T to C, chromosome 10 at 130,472,429 bp
  • T to A, chromosome 11 at 58,338,124 bp
  • T to C, chromosome 11 at 69,448,166 bp
  • G to T, chromosome 11 at 82,036,507 bp
  • T to C, chromosome 11 at 97,114,710 bp
  • G to T, chromosome 11 at 97,378,643 bp
  • A to G, chromosome 12 at 33,358,687 bp
  • A to G, chromosome 12 at 81,214,132 bp
  • A to G, chromosome 12 at 111,448,631 bp
  • T to C, chromosome 12 at 114,153,333 bp
  • A to T, chromosome 12 at 118,254,472 bp
  • A to T, chromosome 13 at 3,574,000 bp
  • C to T, chromosome 13 at 8,888,042 bp
  • T to A, chromosome 13 at 13,636,064 bp
  • T to C, chromosome 13 at 31,627,175 bp
  • C to T, chromosome 13 at 107,726,575 bp
  • T to A, chromosome 14 at 19,415,957 bp
  • A to T, chromosome 14 at 26,735,697 bp
  • T to C, chromosome 14 at 33,152,670 bp
  • A to G, chromosome 14 at 53,717,079 bp
  • A to G, chromosome 14 at 56,635,731 bp
  • A to T, chromosome 14 at 65,076,032 bp
  • T to C, chromosome 15 at 44,457,616 bp
  • T to C, chromosome 15 at 66,285,897 bp
  • T to A, chromosome 15 at 66,827,382 bp
  • T to A, chromosome 15 at 76,070,474 bp
  • T to A, chromosome 16 at 8,843,209 bp
  • A to G, chromosome 16 at 32,626,578 bp
  • A to T, chromosome 17 at 23,859,247 bp
  • T to C, chromosome 17 at 33,381,898 bp
  • T to G, chromosome 17 at 85,032,845 bp
  • A to G, chromosome 18 at 12,582,611 bp
  • A to T, chromosome 19 at 34,594,081 bp
  • C to A, chromosome 19 at 47,107,115 bp
  • C to A, chromosome 19 at 48,759,951 bp
  • T to C, chromosome 19 at 57,386,305 bp
  • A to T, chromosome Y at 726,004 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5049 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042639-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.