Strain Name:
C57BL/6J-MtgxR5062Btlr/Mmmh
Stock Number:
042652-MU
Citation ID:
RRID:MMRRC_042652-MU
Other Names:
R5062 (G1), C57BL/6J-MtgxR5062Btlr
Major Collection:

Gene Information

Otx1
Name: orthodenticle homeobox 1
Synonyms: jv, A730044F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18423
VEGA: 11
HGNC: HGNC:8521
Homologene: 7875
Limch1
Name: LIM and calponin homology domains 1
Synonyms: 3732412D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 77569
VEGA: 5
Homologene: 18953
Nae1
Name: NEDD8 activating enzyme E1 subunit 1
Synonyms: Appbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234664
VEGA: 8
HGNC: HGNC:621
Homologene: 68370
Herc3
Name: hect domain and RLD 3
Synonyms: 5730409F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 73998
VEGA: 6
HGNC: HGNC:4876
Homologene: 57095
Spns1
Name: spinster homolog 1
Synonyms: 2210013K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 73658
VEGA: 7
Homologene: 41530
Slamf6
Name: SLAM family member 6
Synonyms: KAL1b, KAL1, SF2000, Ly108, NTB-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 30925
VEGA: 1
Homologene: 49945
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 2510002A14Rik, 9030227G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 72313
VEGA: 5
Homologene: 103956
Pcm1
Name: pericentriolar material 1
Synonyms: 2600002H09Rik, 9430077F19Rik, C030044G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 18536
VEGA: 8
HGNC: HGNC:8727
Homologene: 4518
Lcmt1
Name: leucine carboxyl methyltransferase 1
Synonyms: Lcmt, LCMT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 30949
VEGA: 7
Homologene: 41123
Nisch
Name: nischarin
Synonyms: 1200007D05Rik, 3202002H23Rik, edsn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 64652
VEGA: 14
Homologene: 136161
Cdca4
Name: cell division cycle associated 4
Synonyms: SEI-3, 2410018C03Rik, Hepp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 71963
VEGA: 12
Homologene: 9936
Pi4ka
Name: phosphatidylinositol 4-kinase alpha
Synonyms: Pik4ca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224020
VEGA: 16
HGNC: HGNC:8983
Homologene: 11171
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: A630086P08Rik, opm, b2b327Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 207304
VEGA: 12
Homologene: 9115
Supt5
Name: suppressor of Ty 5, DSIF elongation factor subunit
Synonyms: Spt5, Supt5h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20924
VEGA: 7
Homologene: 2384
Kctd3
Name: potassium channel tetramerisation domain containing 3
Synonyms: 4930438A20Rik, E330032J19Rik, NY-REN-45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226823
VEGA: 1
Homologene: 9395
Senp3
Name: SUMO/sentrin specific peptidase 3
Synonyms: Smt3ip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 80886
VEGA: 11
Homologene: 9236
Mc5r
Name: melanocortin 5 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 17203
VEGA: 18
HGNC: HGNC:6933
Homologene: 4321
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20191
VEGA: 13
Homologene: 37423
Thbs1
Name: thrombospondin 1
Synonyms: TSP-1, Thbs-1, TSP1, tbsp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 21825
VEGA: 2
Homologene: 31142
Bcam
Name: basal cell adhesion molecule
Synonyms: Lu, B-CAM, 1200005K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 57278
VEGA: 7
HGNC: HGNC:6722
Homologene: 21149
Grm7
Name: glutamate receptor, metabotropic 7
Synonyms: 6330570A01Rik, Tg(SMN2)89Ahmb, mGluR7, E130018M02Rik, SMN2, mGlu7a receptor, Gpr1g
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 108073
VEGA: 6
HGNC: HGNC:4599
Homologene: 20233
Sun2
Name: Sad1 and UNC84 domain containing 2
Synonyms: Unc84b, B230369L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223697
VEGA: 15
Homologene: 9113
Vsir
Name: V-set immunoregulatory receptor
Synonyms: PD-1H, VISTA, Dies1, 4632428N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 74048
VEGA: 10
Homologene: 81923
Casp2
Name: caspase 2
Synonyms: Nedd2, Caspase-2, Ich-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12366
VEGA: 6
HGNC: HGNC:1503
Homologene: 7254
Nectin2
Name: nectin cell adhesion molecule 2
Synonyms: Pvrl2, Pvs, nectin-2, MPH, Cd112
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 19294
VEGA: 7
HGNC: HGNC:9707
Homologene: 86092
Peak1
Name: pseudopodium-enriched atypical kinase 1
Synonyms: C230081A13Rik, 1110049L02Rik, NKF3 kinase family member
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244895
VEGA: 9
Homologene: 18259
Asxl3
Name: additional sex combs like 3, transcriptional regulator
Synonyms: LOC381127, C230079D11Rik, D430002O22Rik, D930044O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 211961
VEGA: 18
Homologene: 19371
Clu
Name: clusterin
Synonyms: Sugp-2, Sgp2, testosterone repressed prostate message-2, Cli, Sgp-2, complement lysis inhibitor, D14Ucla3, Apolipoprotein J, ApoJ, SP-40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 12759
VEGA: 14
HGNC: HGNC:2095
Homologene: 1382
Umod
Name: uromodulin
Synonyms: Tamm-Horsfall glycoprotein, urehr4, uromucoid, Urehd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22242
VEGA: 7
Homologene: 2522
Ncoa1
Name: nuclear receptor coactivator 1
Synonyms: bHLHe74, SRC1, KAT13A, steroid receptor coactivator-1, SRC-a/NCoA-1, SRC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 17977
VEGA: 12
HGNC: HGNC:7668
Homologene: 7859
Atp6v0a4
Name: ATPase, H+ transporting, lysosomal V0 subunit A4
Synonyms: Atp6n1b, V-ATPase alpha 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 140494
VEGA: 6
HGNC: HGNC:866
Homologene: 39904
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: FPC, tigmin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241035
VEGA: 1
HGNC: HGNC:9016
Homologene: 16336
Lamc3
Name: laminin gamma 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 23928
VEGA: 2
HGNC: HGNC:6494
Homologene: 21222
Zfp646
Name: zinc finger protein 646
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233905
Homologene: 8802
Sharpin
Name: SHANK-associated RH domain interacting protein
Synonyms: SIPL1, cpdm, 0610041B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 106025
VEGA: 15
Homologene: 11918
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17996
VEGA: 2
HGNC: HGNC:7720
Homologene: 136285
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12835
VEGA: 1
HGNC: HGNC:2213
Homologene: 37917
Mroh2a
Name: maestro heat-like repeat family member 2A
Synonyms: ENSMUSG00000044873, OTTMUSG00000020804, Heatr7b1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 100040766
Homologene: 85300
Ttc21a
Name: tetratricopeptide repeat domain 21A
Synonyms: 4921538N17Rik, Thm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74052
VEGA: 9
Homologene: 14728
Fshr
Name: follicle stimulating hormone receptor
Synonyms: follicle-stimulating hormone receptor, FSH-R, Follitropin receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14309
VEGA: 17
HGNC: HGNC:3969
Homologene: 117
Abca6
Name: ATP-binding cassette, sub-family A (ABC1), member 6
Synonyms: 6330565N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76184
VEGA: 11
HGNC: HGNC:36
Homologene: 71264
Tns1
Name: tensin 1
Synonyms: Tns, E030037J05Rik, 1110018I21Rik, E030018G17Rik, 1200014E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 21961
VEGA: 1
Homologene: 11219
Cpne9
Name: copine family member IX
Synonyms: A730016F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 211232
VEGA: 6
Homologene: 84686
Fam186a
Name: family with sequence similarity 186, member A
Synonyms: 1700030F18Rik, LOC380973
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 72277
VEGA: 15
Phgdh
Name: 3-phosphoglycerate dehydrogenase
Synonyms: 3PGDH, SERA, 3-PGDH, PGDH, PGD, PGAD, A10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 236539
VEGA: 3
HGNC: HGNC:8923
Homologene: 39318
Fscn2
Name: fascin actin-bundling protein 2
Synonyms: C630046B20Rik, ahl8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 238021
VEGA: 11
HGNC: HGNC:3960
Homologene: 22722
Lrfn2
Name: leucine rich repeat and fibronectin type III domain containing 2
Synonyms: SALM1, 5730420O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 70530
VEGA: 17
Homologene: 19182
Nlrp5
Name: NLR family, pyrin domain containing 5
Synonyms: Nalp5, Mater, Op1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 23968
VEGA: 7
Homologene: 65105
Cyp3a13
Name: cytochrome P450, family 3, subfamily a, polypeptide 13
Synonyms: IIIAm2, steroid inducible
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 13113
VEGA: 5
HGNC: HGNC:2640
Homologene: 133564
Artn
Name: artemin
Synonyms: neublastin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11876
VEGA: 4
HGNC: HGNC:727
Homologene: 7631
Spef1
Name: sperm flagellar 1
Synonyms: 4931426K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 70997
VEGA: 2
Homologene: 15741
Pak1ip1
Name: PAK1 interacting protein 1
Synonyms: 5930415H02Rik, PIP1, p21-activated protein kinase-interacting protein 1, Gdpd1, 5830431I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 68083
VEGA: 13
Homologene: 39574
Klra9
Name: killer cell lectin-like receptor subfamily A, member 9
Synonyms: LY49I1, Ly49I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16640
VEGA: 6
Homologene: 110821
Glyat
Name: glycine-N-acyltransferase
Synonyms: A330009E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107146
VEGA: 19
Homologene: 64840
Sema4c
Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Synonyms: Semacl1, Semaf, M-Sema F, Semacl1, Semai
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20353
VEGA: 1
Homologene: 23047
Klhl30
Name: kelch-like 30
Synonyms: 4631423F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 70788
VEGA: 1
Homologene: 18891
Tmem200a
Name: transmembrane protein 200A
Synonyms: C030003D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 77220
VEGA: 10
Homologene: 14175
Ptgs1
Name: prostaglandin-endoperoxide synthase 1
Synonyms: Pghs1, COX1, Cox-1, cyclooxygenase 1, Cox-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19224
VEGA: 2
HGNC: HGNC:9604
Homologene: 743
Tbx5
Name: T-box 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 21388
VEGA: 5
Homologene: 160
Olfr727
Name: olfactory receptor 727
Synonyms: GA_x6K02T2PMLR-5817082-5818056, MOR246-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258316
VEGA: 14
Homologene: 84571
Cd177
Name: CD177 antigen
Synonyms: Pdp3, 1190003K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68891
VEGA: 7
Homologene: 49628
Akr1b10
Name: aldo-keto reductase family 1, member B10 (aldose reductase)
Synonyms: 2310005E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67861
VEGA: 6
Homologene: 128412
Mknk2
Name: MAP kinase-interacting serine/threonine kinase 2
Synonyms: Mnk2, 2010016G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 17347
VEGA: 10
HGNC: HGNC:7111
Homologene: 49674
Gm5724
Name: predicted gene 5724
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 435927
Ppp2r2b
Name: protein phosphatase 2, regulatory subunit B, beta
Synonyms: 2900026H06Rik, E130009M08Rik, PP2A-PR55B, PR55-BETA, 6330404L05Rik, SCA12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 72930
VEGA: 18
HGNC: HGNC:9305
Homologene: 55833
Plat
Name: plasminogen activator, tissue
Synonyms: D8Ertd2e, t-PA, tPA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 18791
VEGA: 8
HGNC: HGNC:9051
Homologene: 717
Olfr103
Name: olfactory receptor 103
Synonyms: MOR250-3, GA_x6K02T2PSCP-1798423-1797482, MOR250-8_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258830
VEGA: 17
Homologene: 115555
Ccdc137
Name: coiled-coil domain containing 137
Synonyms: 3110023B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67291
VEGA: 11
Homologene: 34992
Tmem140
Name: transmembrane protein 140
Synonyms: 1110007F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 68487
VEGA: 6
Homologene: 10116
Tmem200b
Name: transmembrane protein 200B
Synonyms: EG623230
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 623230
VEGA: 4
Homologene: 79738
Gm6158
Name: predicted gene 6158
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 620499
VEGA: 14
Gm7255
Name: predicted gene 7255
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 638950
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 20,585,711 bp
  • C to T, chromosome 1 at 36,552,978 bp
  • A to T, chromosome 1 at 73,952,864 bp
  • GCCC to GC, chromosome 1 at 88,232,257 bp
  • A to C, chromosome 1 at 90,779,352 bp
  • A to G, chromosome 1 at 91,355,578 bp
  • A to G, chromosome 1 at 171,936,533 bp
  • A to C, chromosome 1 at 188,995,693 bp
  • A to T, chromosome 2 at 31,905,667 bp
  • A to G, chromosome 2 at 36,237,282 bp
  • A to C, chromosome 2 at 52,280,501 bp
  • T to C, chromosome 2 at 118,121,237 bp
  • A to G, chromosome 2 at 131,173,281 bp
  • T to A, chromosome 3 at 98,328,339 bp
  • A to T, chromosome 4 at 117,927,676 bp
  • A to G, chromosome 4 at 131,922,537 bp
  • C to T, chromosome 5 at 66,969,235 bp
  • T to C, chromosome 5 at 73,075,893 bp
  • T to A, chromosome 5 at 119,836,922 bp
  • A to C, chromosome 5 at 137,898,899 bp
  • G to T, chromosome 6 at 34,392,106 bp
  • G to A, chromosome 6 at 34,872,962 bp
  • A to T, chromosome 6 at 38,074,183 bp
  • C to T, chromosome 6 at 42,269,272 bp
  • C to T, chromosome 6 at 58,855,760 bp
  • A to G, chromosome 6 at 110,646,136 bp
  • T to A, chromosome 6 at 113,304,488 bp
  • T to C, chromosome 6 at 130,179,109 bp
  • A to C, chromosome 6 at 141,767,454 bp
  • C to T, chromosome 7 at 19,738,273 bp
  • T to A, chromosome 7 at 19,760,101 bp
  • A to T, chromosome 7 at 23,435,910 bp
  • C to A, chromosome 7 at 24,744,316 bp
  • C to T, chromosome 7 at 28,329,015 bp
  • T to C, chromosome 7 at 47,502,928 bp
  • G to A, chromosome 7 at 119,472,421 bp
  • A to C, chromosome 7 at 123,410,830 bp
  • G to A, chromosome 7 at 126,374,329 bp
  • G to A, chromosome 7 at 127,880,499 bp
  • A to G, chromosome 8 at 22,772,311 bp
  • T to C, chromosome 8 at 41,259,260 bp
  • A to T, chromosome 8 at 104,516,702 bp
  • G to T, chromosome 9 at 56,260,289 bp
  • T to C, chromosome 9 at 119,956,971 bp
  • T to A, chromosome 10 at 25,993,915 bp
  • A to G, chromosome 10 at 60,364,263 bp
  • G to A, chromosome 10 at 80,671,769 bp
  • C to A, chromosome 11 at 21,997,037 bp
  • A to G, chromosome 11 at 69,678,964 bp
  • A to T, chromosome 11 at 110,177,066 bp
  • A to C, chromosome 11 at 120,366,749 bp
  • A to G, chromosome 11 at 120,462,515 bp
  • A to G, chromosome 12 at 4,259,333 bp
  • A to T, chromosome 12 at 51,744,879 bp
  • T to C, chromosome 12 at 112,821,863 bp
  • T to C, chromosome 13 at 11,700,354 bp
  • A to G, chromosome 13 at 41,008,145 bp
  • A to T, chromosome 14 at 24,070,090 bp
  • T to A, chromosome 14 at 31,172,440 bp
  • T to A, chromosome 14 at 50,127,437 bp
  • A to C, chromosome 14 at 65,979,728 bp
  • T to C, chromosome 15 at 76,347,611 bp
  • T to C, chromosome 15 at 79,728,536 bp
  • A to C, chromosome 15 at 99,944,646 bp
  • G to T, chromosome 16 at 17,309,397 bp
  • A to T, chromosome 17 at 37,336,931 bp
  • A to G, chromosome 17 at 49,070,500 bp
  • A to T, chromosome 17 at 88,986,046 bp
  • T to A, chromosome 18 at 22,522,718 bp
  • C to A, chromosome 18 at 42,688,461 bp
  • T to C, chromosome 18 at 68,339,281 bp
  • A to C, chromosome 19 at 12,650,263 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5062 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042652-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.