Strain Name:
C57BL/6J-MtgxR5110Btlr/Mmmh
Stock Number:
042698-MU
Citation ID:
RRID:MMRRC_042698-MU
Other Names:
R5110 (G1), C57BL/6J-MtgxR5110Btlr
Major Collection:

Gene Information

Col1a1
Name: collagen, type I, alpha 1
Synonyms: Mov-13, Cola1, Col1a-1, Cola-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12842
HGNC: HGNC:2197
Homologene: 73874
Sbf2
Name: SET binding factor 2
Synonyms: B430219L04Rik, SBF2, 4833411B01Rik, mMTMH1, Mtmr13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 319934
HGNC: HGNC:2135
Homologene: 41810
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Aclp7, Acf7, trabeculin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11426
Homologene: 136191
Rai14
Name: retinoic acid induced 14
Synonyms: Norpeg, Ankycorbin, 1700020L11Rik, 1700008J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 75646
VEGA: 15
Homologene: 9199
Ehmt1
Name: euchromatic histone methyltransferase 1
Synonyms: 9230102N17Rik, KMT1D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 77683
Homologene: 11698
St5
Name: suppression of tumorigenicity 5
Synonyms: 2010004M01Rik, 2610305K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76954
Homologene: 3951
Cwf19l2
Name: CWF19-like 2, cell cycle control (S. pombe)
Synonyms: 3230401L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244672
Homologene: 12366
Zfp13
Name: zinc finger protein 13
Synonyms: Krox-8, Zfp-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 22654
VEGA: 17
Homologene: 2580
Synj2
Name: synaptojanin 2
Synonyms: SJ2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20975
Homologene: 117703
Smarcc1
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
Synonyms: BAF155, msp3, SRG3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20588
Homologene: 68296
Ktn1
Name: kinectin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16709
HGNC: HGNC:6467
Homologene: 7397
Enox1
Name: ecto-NOX disulfide-thiol exchanger 1
Synonyms: D230005D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239188
VEGA: 14
Homologene: 56793
Golga5
Name: golgi autoantigen, golgin subfamily a, 5
Synonyms: Ret-II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 27277
VEGA: 12
HGNC: HGNC:4428
Homologene: 38009
Tubgcp5
Name: tubulin, gamma complex associated protein 5
Synonyms: B130010C12Rik, GCP5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233276
Homologene: 14172
Pptc7
Name: PTC7 protein phosphatase homolog
Synonyms: 9130017A15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 320717
Homologene: 6100
Abi2
Name: abl-interactor 2
Synonyms: 8430425M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329165
Homologene: 4209
Als2
Name: alsin Rho guanine nucleotide exchange factor
Synonyms: Als2cr6, Alsin, 3222402C23Rik, 9430073A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74018
HGNC: HGNC:443
Homologene: 23264
Pparg
Name: peroxisome proliferator activated receptor gamma
Synonyms: Nr1c3, PPARgamma2, Ppar-gamma2, PPAR-gamma, PPARgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 19016
HGNC: HGNC:9236
Homologene: 7899
Dctn4
Name: dynactin 4
Synonyms: 4930547K17Rik, 1110001K06Rik, p62, C130039E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 67665
VEGA: 18
Homologene: 9430
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 2310042E16Rik, Coh1, 1810042B05Rik, C330002D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Adam33
Name: a disintegrin and metallopeptidase domain 33
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 110751
Homologene: 11881
Hk1
Name: hexokinase 1
Synonyms: Hk1-s, Hk-1, mHk1-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 15275
HGNC: HGNC:4922
Homologene: 100530
Ptprs
Name: protein tyrosine phosphatase, receptor type, S
Synonyms: PTP-NU3, PTPsigma, Ptpt9, RPTPsigma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 19280
HGNC: HGNC:9681
Homologene: 20626
Stim1
Name: stromal interaction molecule 1
Synonyms: SIM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20866
Homologene: 20681
Ift81
Name: intraflagellar transport 81
Synonyms: Cdv1, CDV-1R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12589
Homologene: 7664
Cdc23
Name: CDC23 cell division cycle 23
Synonyms: D18Ertd243e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 52563
HGNC: HGNC:1724
Homologene: 3426
Ttc8
Name: tetratricopeptide repeat domain 8
Synonyms: BBS8, 0610012F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 76260
Homologene: 14988
Zscan10
Name: zinc finger and SCAN domain containing 10
Synonyms: Zfp206, Zscan10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 332221
Homologene: 13122
Miox
Name: myo-inositol oxygenase
Synonyms: RSOR, C85427, Aldrl6, 0610009I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 56727
Homologene: 9732
Slc1a1
Name: solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
Synonyms: D130048G10Rik, EAAT3, MEAAC1, EAAC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 20510
Homologene: 20881
1700010I14Rik
Name: RIKEN cDNA 1700010I14 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 66931
Homologene: 49841
2310016G11Rik
Name: RIKEN cDNA 2310016G11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 69578
Per2
Name: period circadian clock 2
Synonyms: mPer2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18627
HGNC: HGNC:8846
Homologene: 7885
Lrp4
Name: low density lipoprotein receptor-related protein 4
Synonyms: 6430526J12Rik, mdig, Megf7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228357
HGNC: HGNC:6696
Homologene: 17964
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: 1110004P15Rik, 2310047C17Rik, DY6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Fzd1
Name: frizzled class receptor 1
Synonyms: FZ-1, Fz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14362
HGNC: HGNC:4038
Homologene: 20750
Vmn1r194
Name: vomeronasal 1 receptor 194
Synonyms: Gm11294
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 626299
Homologene: 110880
Map3k6
Name: mitogen-activated protein kinase kinase kinase 6
Synonyms: Ask2, MEKK6, MAPKKK6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 53608
HGNC: HGNC:6858
Homologene: 3435
Hsf4
Name: heat shock transcription factor 4
Synonyms: ldis1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 26386
HGNC: HGNC:5227
Homologene: 100128
Adamts15
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235130
VEGA: 9
Homologene: 8610
Usp4
Name: ubiquitin specific peptidase 4 (proto-oncogene)
Synonyms: F730026I20Rik, Unp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22258
Homologene: 20716
Tinag
Name: tubulointerstitial nephritis antigen
Synonyms: TIN-ag
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 26944
Homologene: 8082
Prpf19
Name: pre-mRNA processing factor 19
Synonyms: Snev, Prp19, D19Wsu55e, PSO4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 28000
Homologene: 6421
Kcnh1
Name: potassium voltage-gated channel, subfamily H (eag-related), member 1
Synonyms: ether a go-go, Kv10.1, Eag1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16510
HGNC: HGNC:6250
Homologene: 68242
Sardh
Name: sarcosine dehydrogenase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 192166
Homologene: 5149
Ovgp1
Name: oviductal glycoprotein 1
Synonyms: OGP, Chit5, MOGP, muc9, mucin 9, oviductin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12659
HGNC: HGNC:8524
Homologene: 74442
Adam21
Name: a disintegrin and metallopeptidase domain 21
Synonyms: ADAM31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 56622
HGNC: HGNC:200
Homologene: 68365
Vmn2r101
Name: vomeronasal 2, receptor 101
Synonyms: EG627576
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 627576
Homologene: 115024
Car15
Name: carbonic anhydrase 15
Synonyms: Cals2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 80733
Homologene: 113791
Syne3
Name: spectrin repeat containing, nuclear envelope family member 3
Synonyms: nesprin-3, nesprin-3beta, nesprin-3alpha, 4831426I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 212073
VEGA: 12
Homologene: 17625
Clec12a
Name: C-type lectin domain family 12, member a
Synonyms: Micl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232413
Homologene: 51378
Col25a1
Name: collagen, type XXV, alpha 1
Synonyms: 2700062B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 77018
Homologene: 57111
Ugt1a10
Name: UDP glycosyltransferase 1 family, polypeptide A10
Synonyms: A13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 394430
Homologene: 133281
Igkv13-84
Name: immunoglobulin kappa chain variable 13-84
Synonyms: Igk-V33
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 692152
Fam136b-ps
Name: family with sequence similarity 136, member B, pseudogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 625796
VEGA: 15
Olfr722
Name: olfactory receptor 722
Synonyms: MOR241-3, GA_x6K02T2PMLR-5566715-5565789
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258487
Homologene: 17270
Aicda
Name: activation-induced cytidine deaminase
Synonyms: Aid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 11628
Homologene: 7623
2010315B03Rik
Name: RIKEN cDNA 2010315B03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 630836
Homologene: 136499
Gm26883
Name: predicted gene, 26883
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 59,185,441 bp
  • G to A, chromosome 1 at 60,450,121 bp
  • T to A, chromosome 1 at 88,056,252 bp
  • G to A, chromosome 1 at 91,429,515 bp
  • T to A, chromosome 1 at 192,337,747 bp
  • C to A, chromosome 2 at 24,852,790 bp
  • T to C, chromosome 2 at 27,189,547 bp
  • A to T, chromosome 2 at 91,497,072 bp
  • A to T, chromosome 2 at 131,053,770 bp
  • A to G, chromosome 2 at 169,884,197 bp
  • G to C, chromosome 3 at 105,977,783 bp
  • A to G, chromosome 3 at 130,584,725 bp
  • A to T, chromosome 4 at 123,368,008 bp
  • G to A, chromosome 4 at 133,247,548 bp
  • T to C, chromosome 5 at 4,756,448 bp
  • T to A, chromosome 5 at 122,308,249 bp
  • A to G, chromosome 5 at 122,551,058 bp
  • T to C, chromosome 6 at 68,939,608 bp
  • T to C, chromosome 6 at 115,473,003 bp
  • A to G, chromosome 6 at 122,561,185 bp
  • A to G, chromosome 6 at 129,350,429 bp
  • G to A, chromosome 7 at 44,677,862 bp
  • G to A, chromosome 7 at 55,808,637 bp
  • T to C, chromosome 7 at 102,268,422 bp
  • A to G, chromosome 7 at 109,542,490 bp
  • T to A, chromosome 7 at 110,364,657 bp
  • A to G, chromosome 8 at 105,272,795 bp
  • A to G, chromosome 9 at 3,450,012 bp
  • A to G, chromosome 9 at 30,921,444 bp
  • A to G, chromosome 9 at 76,952,007 bp
  • T to A, chromosome 9 at 108,362,678 bp
  • A to G, chromosome 9 at 110,197,784 bp
  • C to A, chromosome 9 at 124,295,357 bp
  • A to T, chromosome 10 at 62,286,651 bp
  • T to C, chromosome 11 at 94,941,593 bp
  • T to C, chromosome 12 at 81,560,215 bp
  • T to C, chromosome 12 at 98,942,303 bp
  • G to A, chromosome 12 at 102,472,077 bp
  • G to A, chromosome 12 at 104,943,370 bp
  • T to G, chromosome 13 at 22,245,000 bp
  • A to G, chromosome 14 at 47,704,287 bp
  • T to G, chromosome 14 at 49,895,575 bp
  • T to C, chromosome 14 at 77,707,687 bp
  • T to C, chromosome 15 at 10,690,410 bp
  • A to G, chromosome 15 at 31,276,710 bp
  • T to A, chromosome 15 at 35,770,809 bp
  • T to A, chromosome 15 at 89,335,556 bp
  • T to C, chromosome 16 at 17,835,347 bp
  • T to C, chromosome 17 at 6,037,715 bp
  • T to C, chromosome 17 at 8,992,353 bp
  • T to C, chromosome 17 at 19,611,635 bp
  • C to A, chromosome 17 at 23,580,860 bp
  • T to A, chromosome 17 at 23,609,632 bp
  • T to C, chromosome 17 at 56,423,527 bp
  • C to A, chromosome 18 at 34,651,689 bp
  • C to T, chromosome 18 at 60,546,315 bp
  • A to T, chromosome 19 at 9,014,759 bp
  • T to C, chromosome 19 at 10,899,287 bp
  • G to A, chromosome 19 at 28,911,808 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5110 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042698-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.