Strain Name:
C57BL/6J-MtgxR5156Btlr/Mmmh
Stock Number:
042738-MU
Citation ID:
RRID:MMRRC_042738-MU
Other Names:
R5156 (G1), C57BL/6J-MtgxR5156Btlr
Major Collection:

Gene Information

Ppp1r37
Name: protein phosphatase 1, regulatory subunit 37
Synonyms: Lrrc68
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232947
Homologene: 17851
Ctage5
Name: CTAGE family, member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
Asf1b
Name: anti-silencing function 1B histone chaperone
Synonyms: 1700003K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 66929
Homologene: 56797
Arap2
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms: Centd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 212285
Homologene: 9064
Plekha5
Name: pleckstrin homology domain containing, family A member 5
Synonyms: Ayu21-9, Gt(Ayu21)9Imeg, AMH-Cre, PEPP2, 2810431N21Rik, Tg(AMH-cre)1Flor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 109135
Homologene: 10377
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: Dnec1, dynein heavy chain, retrograde transport, MAP1C, 9930018I23Rik, Swl, Loa, Dnchc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
Epha8
Name: Eph receptor A8
Synonyms: Eek, Hek3, EphA8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13842
HGNC: HGNC:3391
Homologene: 22436
Dmbt1
Name: deleted in malignant brain tumors 1
Synonyms: gp300, Crpd, hensin, ebnerin, CRP-[a], vomeroglandin, CRP-[b], MUCLIN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12945
HGNC: HGNC:2926
Homologene: 68990
Fzd10
Name: frizzled class receptor 10
Synonyms: Fz-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 93897
HGNC: HGNC:4039
Homologene: 21411
Ikzf1
Name: IKAROS family zinc finger 1
Synonyms: Zfpn1a1, LyF-1, 5832432G11Rik, Ikaros
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 22778
Homologene: 55948
Slitrk3
Name: SLIT and NTRK-like family, member 3
Synonyms: ST3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 386750
Homologene: 8955
Efemp2
Name: epidermal growth factor-containing fibulin-like extracellular matrix protein 2
Synonyms: MBP1, Fbln4, fibulin-4, fibulin 4, 0610011K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 58859
HGNC: HGNC:3219
Homologene: 32339
Sec13
Name: SEC13 homolog, nuclear pore and COPII coat complex component
Synonyms: Sec13r, 1110003H02Rik, Sec13l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 110379
Homologene: 6479
Foxk1
Name: forkhead box K1
Synonyms: Mnf, A630048H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 17425
Homologene: 82414
Edrf1
Name: erythroid differentiation regulatory factor 1
Synonyms: 2700050L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 214764
Homologene: 27985
Tnfsfm13
Name: tumor necrosis factor (ligand) superfamily, membrane-bound member 13
Synonyms: Tnfsf12-Tnfsf13, TWE-PRIL, Tnfsf12tnfsf13, BC096441
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 619441
Homologene: 123930
Muc19
Name: mucin 19
Synonyms: apomucin, sld
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239611
Homologene: null
Apeh
Name: acylpeptide hydrolase
Synonyms: N-acylaminoacyl peptide hydrolase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235606
HGNC: HGNC:586
Homologene: 1240
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hy-3, hy3, 1700034M11Rik, hyrh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244653
Homologene: 52118
Dmpk
Name: dystrophia myotonica-protein kinase
Synonyms: DM, Dm15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13400
HGNC: HGNC:2933
Homologene: 3247
Cfap53
Name: cilia and flagella associated protein 53
Synonyms: Ccdc11, 4933415I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 74453
Homologene: 27056
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: VLGR1, Mgr1, Mass1, Gpr98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 110789
Homologene: 19815
Neu4
Name: sialidase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241159
Homologene: 15433
Csf1
Name: colony stimulating factor 1 (macrophage)
Synonyms: M-CSF, CSF-1, colony-stimulating factor-1, Csfm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12977
HGNC: HGNC:2432
Homologene: 7282
Clca3a2
Name: chloride channel accessory 3A2
Synonyms: Clca2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 80797
HGNC: null
Homologene: 77224
Vmn2r10
Name: vomeronasal 2, receptor 10
Synonyms: VR16, V2r16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22307
HGNC: null
Homologene: 129606
Trank1
Name: tetratricopeptide repeat and ankyrin repeat containing 1
Synonyms: A230061D21Rik, C030048J01Rik, Lba1, LOC235639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 320429
Homologene: 45845
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 75777
Homologene: 44907
Vmn2r75
Name: vomeronasal 2, receptor 75
Synonyms: EG546981
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 546981
HGNC: null
Homologene: 115466
Vwa8
Name: von Willebrand factor A domain containing 8
Synonyms: 4932416F07Rik, 1300010F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219189
VEGA: 14
Homologene: 44881
Krt20
Name: keratin 20
Synonyms: CK20, cytokeratin 20, 9030623C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66809
Homologene: 56837
Rfx4
Name: regulatory factor X, 4 (influences HLA class II expression)
Synonyms: 4933412G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71137
HGNC: HGNC:9985
Homologene: 31119
Trim10
Name: tripartite motif-containing 10
Synonyms: Rnf9, Herf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 19824
Homologene: 4932
Speg
Name: SPEG complex locus
Synonyms: Apeg1, SPEGalpha, SPEG, BPEG, SPEGbeta, D1Bwg1450e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11790
Homologene: 55619
Sp100
Name: nuclear antigen Sp100
Synonyms: A430075G10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20684
Homologene: 86761
Ppef2
Name: protein phosphatase, EF hand calcium-binding domain 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19023
HGNC: HGNC:9244
Homologene: 55959
Nrap
Name: nebulin-related anchoring protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18175
HGNC: HGNC:7988
Homologene: 4499
0610010F05Rik
Name: RIKEN cDNA 0610010F05 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71675
Homologene: 19038
Olfr1474
Name: olfactory receptor 1474
Synonyms: GA_x6K02T2RE5P-3803583-3804527, MOR202-26P, MOR202-42
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258123
HGNC: null
Homologene: 79417
Olfr228
Name: olfactory receptor 228
Synonyms: MOR189-3, GA_x6K02T0101M-139-669
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258400
HGNC: null
Homologene: 17233
Cd46
Name: CD46 antigen, complement regulatory protein
Synonyms: CD46, Mcp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17221
HGNC: HGNC:6953
Homologene: 7832
4921513D11Rik
Name: RIKEN cDNA 4921513D11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: null
Ensembl: null
VEGA: null
HGNC: null
Homologene: null
Lrrc71
Name: leucine rich repeat containing 71
Synonyms: 4933430H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74485
Homologene: 83646
Spata2
Name: spermatogenesis associated 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 263876
Homologene: 4407
Nt5m
Name: 5',3'-nucleotidase, mitochondrial
Synonyms: dNT-2, 2010013E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 103850
Homologene: 10622
Olfr1138
Name: olfactory receptor 1138
Synonyms: GA_x6K02T2Q125-49242149-49241214, MOR177-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258632
HGNC: null
Homologene: 74082
Cdca7
Name: cell division cycle associated 7
Synonyms: 2310021G01Rik, JPO1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66953
Homologene: 49970
Dnajb12
Name: DnaJ heat shock protein family (Hsp40) member B12
Synonyms: mDj10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 56709
Homologene: 9749
Serhl
Name: serine hydrolase-like
Synonyms: 1110019M09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 68607
Homologene: 65196
Slco4a1
Name: solute carrier organic anion transporter family, member 4a1
Synonyms: Slc21a12, OATP-E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 108115
Homologene: 9482
C87414
Name: expressed sequence C87414
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 381654
HGNC: null
Homologene: 133100
Gm6818
Name: predicted gene 6818
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 627975
HGNC: null
Homologene: 80005
AC107766.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
Gm13991
Name: predicted gene 13991
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 433464
HGNC: null
Homologene: null
RP23-3C4.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 34,723,274 bp
  • T to C, chromosome 1 at 75,428,087 bp
  • T to A, chromosome 1 at 85,673,683 bp
  • T to C, chromosome 1 at 94,024,455 bp
  • T to A, chromosome 1 at 195,085,385 bp
  • A to T, chromosome 2 at 72,479,026 bp
  • A to T, chromosome 2 at 86,483,018 bp
  • G to A, chromosome 2 at 87,737,775 bp
  • T to C, chromosome 2 at 116,528,184 bp
  • G to T, chromosome 2 at 167,483,574 bp
  • T to C, chromosome 2 at 180,472,779 bp
  • T to C, chromosome 3 at 73,049,259 bp
  • T to A, chromosome 3 at 87,745,787 bp
  • T to G, chromosome 3 at 98,124,310 bp
  • T to A, chromosome 3 at 107,748,936 bp
  • T to A, chromosome 3 at 144,805,838 bp
  • C to T, chromosome 4 at 136,938,726 bp
  • A to T, chromosome 5 at 62,669,181 bp
  • A to G, chromosome 5 at 92,244,602 bp
  • G to A, chromosome 5 at 93,638,705 bp
  • A to G, chromosome 5 at 108,995,600 bp
  • C to A, chromosome 5 at 128,601,302 bp
  • A to G, chromosome 5 at 142,448,833 bp
  • G to A, chromosome 6 at 113,730,876 bp
  • C to T, chromosome 6 at 140,426,528 bp
  • A to G, chromosome 7 at 19,084,125 bp
  • T to C, chromosome 7 at 19,561,975 bp
  • A to T, chromosome 7 at 38,402,047 bp
  • T to A, chromosome 7 at 86,164,228 bp
  • T to C, chromosome 7 at 131,097,670 bp
  • C to T, chromosome 7 at 133,660,179 bp
  • T to C, chromosome 8 at 83,955,911 bp
  • T to A, chromosome 8 at 110,609,701 bp
  • C to T, chromosome 9 at 108,094,287 bp
  • A to G, chromosome 9 at 111,390,694 bp
  • T to A, chromosome 10 at 59,892,960 bp
  • T to C, chromosome 10 at 84,868,354 bp
  • T to A, chromosome 11 at 11,769,448 bp
  • A to G, chromosome 11 at 23,593,424 bp
  • A to T, chromosome 11 at 59,874,661 bp
  • A to G, chromosome 11 at 69,687,329 bp
  • G to T, chromosome 11 at 99,430,053 bp
  • A to G, chromosome 12 at 59,172,537 bp
  • T to A, chromosome 12 at 110,628,830 bp
  • T to A, chromosome 13 at 81,520,642 bp
  • T to A, chromosome 14 at 78,984,226 bp
  • G to T, chromosome 15 at 10,551,550 bp
  • G to A, chromosome 15 at 83,102,694 bp
  • T to A, chromosome 15 at 91,900,420 bp
  • T to A, chromosome 17 at 36,877,056 bp
  • G to T, chromosome 17 at 79,628,209 bp
  • T to A, chromosome 18 at 74,359,767 bp
  • T to A, chromosome 19 at 5,477,678 bp
  • G to T, chromosome 19 at 13,471,673 bp
  • A to G, chromosome 19 at 56,371,845 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5156 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042738-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.