Strain Name:
C57BL/6J-MtgxR5162Btlr/Mmmh
Stock Number:
042744-MU
Citation ID:
RRID:MMRRC_042744-MU
Other Names:
R5162 (G1), C57BL/6J-MtgxR5162Btlr
Major Collection:

Gene Information

Faah
Name: fatty acid amide hydrolase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 14073
HGNC: HGNC:3553
Homologene: 68184
Gcm2
Name: glial cells missing homolog 2
Synonyms: Gcm1-rs2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 107889
VEGA: 13
HGNC: HGNC:4198
Homologene: 3490
Ehmt1
Name: euchromatic histone methyltransferase 1
Synonyms: 9230102N17Rik, KMT1D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 77683
Homologene: 11698
Spred1
Name: sprouty protein with EVH-1 domain 1, related sequence
Synonyms: Spred-1, 5730461F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 114715
Homologene: 24919
Enpp2
Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
Synonyms: Autotaxin, ATX, PD-Ialpha, Npps2, Pdnp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18606
HGNC: HGNC:3357
Homologene: 4526
Tyw5
Name: tRNA-yW synthesizing protein 5
Synonyms: 1110034B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68736
Homologene: 72085
Msh2
Name: mutS homolog 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17685
HGNC: HGNC:7325
Homologene: 210
Cry1
Name: cryptochrome 1 (photolyase-like)
Synonyms: Phll1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 12952
VEGA: 10
HGNC: HGNC:2384
Homologene: 7042
Trim23
Name: tripartite motif-containing 23
Synonyms: 6330516O20Rik, Arfd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 81003
HGNC: HGNC:660
Homologene: 1251
Mpp6
Name: membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
Synonyms: P55t, Pals2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 56524
Homologene: 22976
Ccdc141
Name: coiled-coil domain containing 141
Synonyms: 2610301F02Rik, CAMDI, ENSMUSG00000075261
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 545428
Homologene: 52149
Vps18
Name: VPS18 CORVET/HOPS core subunit
Synonyms: 9930024E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228545
Homologene: 13302
Utp25
Name: UTP25 small subunit processome component
Synonyms: Diexf, AA408296
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 215193
Homologene: 6170
Tsg101
Name: tumor susceptibility gene 101
Synonyms: CC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22088
Homologene: 4584
Bcor
Name: BCL6 interacting corepressor
Synonyms: 8430401K06Rik, D930024N20Rik, 5830466J11Rik, 2900008C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 71458
Homologene: 9809
Numbl
Name: numb-like
Synonyms: nbl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18223
HGNC: HGNC:8061
Homologene: 68413
Mdh2
Name: malate dehydrogenase 2, NAD (mitochondrial)
Synonyms: Mor-1, Mdh-2, Mor1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 17448
HGNC: HGNC:6971
Homologene: 55938
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Ncoa2
Name: nuclear receptor coactivator 2
Synonyms: SRC-2, TIF-2, D1Ertd433e, TIF2, Grip1, bHLHe75, glucocorticoid receptor-interacting protein 1, KAT13C, TIF2/GRIP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17978
HGNC: HGNC:7669
Homologene: 4768
Raver2
Name: ribonucleoprotein, PTB-binding 2
Synonyms: A430091O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242570
Homologene: 18829
Prdm10
Name: PR domain containing 10
Synonyms: LOC382066, tristanin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 382066
Homologene: 45718
Slc38a6
Name: solute carrier family 38, member 6
Synonyms: EG625098
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 625098
Homologene: 27550
Dnajc13
Name: DnaJ heat shock protein family (Hsp40) member C13
Synonyms: D030002L11Rik, LOC382100, Rme8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235567
Homologene: 13574
Pkp2
Name: plakophilin 2
Synonyms: Pkp2l, 1200012P04Rik, 1200008D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 67451
HGNC: HGNC:9024
Homologene: 3364
Atp8b1
Name: ATPase, class I, type 8B, member 1
Synonyms: Ic, FIC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 54670
VEGA: 18
HGNC: HGNC:3706
Homologene: 21151
Grn
Name: granulin
Synonyms: progranulin, epithelin, PC cell-derived growth factor, Pgrn, acrogranulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14824
HGNC: HGNC:4601
Homologene: 1577
Mocos
Name: molybdenum cofactor sulfurase
Synonyms: 1110018O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 68591
VEGA: 18
Homologene: 9931
Naip5
Name: NLR family, apoptosis inhibitory protein 5
Synonyms: Birc1e, Naip-rs3, Lgn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17951
HGNC: HGNC:7634
Homologene: 113589
Dhx36
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 36
Synonyms: Ddx36, 2810407E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 72162
Homologene: 6356
Pramef12
Name: PRAME family member 12
Synonyms: 4930569K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 77632
Homologene: 135701
Ptpro
Name: protein tyrosine phosphatase, receptor type, O
Synonyms: D28, PTP-U2, GLEPP1, PTP-oc, PTPROt, Ptpn15, PTP-phi, PTP-BK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 19277
HGNC: HGNC:9678
Homologene: 21564
Fgd5
Name: FYVE, RhoGEF and PH domain containing 5
Synonyms: ZFYVE23, C330025N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232237
Homologene: 27798
Naip6
Name: NLR family, apoptosis inhibitory protein 6
Synonyms: Birc1f, Naip-rs4, Naip-rs4A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17952
HGNC: HGNC:7634
Homologene: 113589
Syt11
Name: synaptotagmin XI
Synonyms: 6530420C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229521
Homologene: 23120
Henmt1
Name: HEN1 methyltransferase homolog 1 (Arabidopsis)
Synonyms: 4921515J06Rik, Hen1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66715
Homologene: 32638
Ak9
Name: adenylate kinase 9
Synonyms: Akd1, Akd2, Gm7127, LOC215946
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 633979
Homologene: 67934
Dpp6
Name: dipeptidylpeptidase 6
Synonyms: LOC384168, Rw, B930011P16Rik, Peplb, In(5)6H-p, Dpp-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 13483
HGNC: HGNC:3010
Homologene: 22560
Zfp93
Name: zinc finger protein 93
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22755
Homologene: 117959
Vmn2r89
Name: vomeronasal 2, receptor 89
Synonyms: V2r10, V2r11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 22301
Slc29a4
Name: solute carrier family 29 (nucleoside transporters), member 4
Synonyms: ENT4, mPMAT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 243328
Homologene: 71345
Cyp3a57
Name: cytochrome P450, family 3, subfamily a, polypeptide 57
Synonyms: EG622127
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 622127
Homologene: 135775
Rnf130
Name: ring finger protein 130
Synonyms: G1RZFP, G1RP, 2510042A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 59044
Homologene: 41267
Fbxo8
Name: F-box protein 8
Synonyms: Fbx8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 50753
Homologene: 8137
Sptlc3
Name: serine palmitoyltransferase, long chain base subunit 3
Synonyms: C130053K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228677
Homologene: 105590
Fn3krp
Name: fructosamine 3 kinase related protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 238024
Homologene: 11093
H2-T10
Name: histocompatibility 2, T region locus 10
Synonyms: H-2T10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 15024
Fnip2
Name: folliculin interacting protein 2
Synonyms: D630023B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 329679
Homologene: 46417
Olfr459
Name: olfactory receptor 459
Synonyms: GA_x6K02T2P3E9-5780974-5781915, MOR120-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 258569
Homologene: 83448
Esrp2
Name: epithelial splicing regulatory protein 2
Synonyms: 9530027K23Rik, Rbm35b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 77411
Homologene: 32617
Vmn1r17
Name: vomeronasal 1 receptor 17
Synonyms: V1rc16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 171189
Homologene: 115643
Plod3
Name: procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
Synonyms: lysyl hydroxylase 3, LH3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 26433
HGNC: HGNC:9083
Homologene: 843
Nars2
Name: asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244141
Homologene: 57002
Nlrp4g
Name: NLR family, pyrin domain containing 4G
Synonyms: nalp4g
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235779
VEGA: 9
Adrb3
Name: adrenergic receptor, beta 3
Synonyms: Beta-3 AR, beta 3-AR, beta3-adrenergic receptor, Adrb-3, Beta-3 adrenoceptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11556
HGNC: HGNC:288
Homologene: 37250
Man1b1
Name: mannosidase, alpha, class 1B, member 1
Synonyms: MANA-ER, E430019H13Rik, LOC227619
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227619
HGNC: HGNC:6823
Homologene: 5230
Olfr761
Name: olfactory receptor 761
Synonyms: MOR218-6P, MOR218-6P, Olfr1552-ps1, MOR218-12, MOR218-5P, GA_x6K02T2PSCP-2403971-2403000
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258094
Homologene: 134080
Pars2
Name: prolyl-tRNA synthetase (mitochondrial)(putative)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230577
Homologene: 5830
Cstdc3
Name: cystatin domain containing 3
Synonyms: Gm4758
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 209324
VEGA: 16
HGNC: HGNC:2481
Homologene: 86375
2010315B03Rik
Name: RIKEN cDNA 2010315B03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 630836
Homologene: 136499
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 13,175,172 bp
  • T to C, chromosome 1 at 57,401,459 bp
  • G to T, chromosome 1 at 193,113,781 bp
  • G to T, chromosome 2 at 24,877,497 bp
  • T to A, chromosome 2 at 25,343,353 bp
  • C to A, chromosome 2 at 77,015,137 bp
  • T to C, chromosome 2 at 117,177,621 bp
  • A to G, chromosome 2 at 119,292,942 bp
  • T to A, chromosome 2 at 139,631,343 bp
  • A to T, chromosome 3 at 62,493,780 bp
  • T to C, chromosome 3 at 79,481,777 bp
  • T to C, chromosome 3 at 88,747,842 bp
  • T to C, chromosome 3 at 108,940,050 bp
  • T to C, chromosome 4 at 101,102,724 bp
  • A to G, chromosome 4 at 106,654,538 bp
  • A to T, chromosome 4 at 116,000,741 bp
  • A to T, chromosome 4 at 144,394,912 bp
  • A to G, chromosome 5 at 27,399,015 bp
  • T to C, chromosome 5 at 135,783,475 bp
  • T to C, chromosome 5 at 136,991,307 bp
  • G to A, chromosome 5 at 142,721,452 bp
  • T to A, chromosome 5 at 145,369,083 bp
  • G to T, chromosome 6 at 41,771,772 bp
  • T to A, chromosome 6 at 50,178,515 bp
  • A to G, chromosome 6 at 57,360,843 bp
  • A to G, chromosome 6 at 92,074,234 bp
  • T to A, chromosome 6 at 137,443,594 bp
  • C to G, chromosome 7 at 24,276,332 bp
  • C to T, chromosome 7 at 27,281,361 bp
  • T to C, chromosome 7 at 46,892,426 bp
  • T to C, chromosome 7 at 97,059,820 bp
  • T to C, chromosome 8 at 27,227,320 bp
  • G to A, chromosome 8 at 45,025,809 bp
  • A to T, chromosome 8 at 56,569,319 bp
  • T to C, chromosome 8 at 106,133,298 bp
  • A to T, chromosome 9 at 31,340,418 bp
  • A to G, chromosome 9 at 104,197,209 bp
  • T to A, chromosome 9 at 124,293,671 bp
  • T to A, chromosome 9 at 124,350,394 bp
  • T to A, chromosome 10 at 41,357,657 bp
  • T to A, chromosome 10 at 85,133,286 bp
  • G to C, chromosome 11 at 50,052,895 bp
  • C to A, chromosome 11 at 102,430,554 bp
  • T to C, chromosome 11 at 121,429,584 bp
  • T to A, chromosome 12 at 73,329,985 bp
  • T to C, chromosome 13 at 41,103,655 bp
  • T to A, chromosome 13 at 100,223,406 bp
  • C to T, chromosome 13 at 100,300,600 bp
  • C to T, chromosome 13 at 104,181,174 bp
  • C to A, chromosome 14 at 51,456,163 bp
  • T to C, chromosome 15 at 54,847,296 bp
  • T to C, chromosome 16 at 16,260,336 bp
  • A to T, chromosome 16 at 36,312,556 bp
  • T to A, chromosome 17 at 36,118,951 bp
  • T to A, chromosome 17 at 37,952,364 bp
  • C to A, chromosome 17 at 87,723,413 bp
  • T to C, chromosome 18 at 24,654,052 bp
  • T to C, chromosome 18 at 64,561,662 bp
  • C to T, chromosome X at 12,040,486 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5162 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042744-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.