Strain Name:
C57BL/6J-MtgxR5237Btlr/Mmmh
Stock Number:
042808-MU
Citation ID:
RRID:MMRRC_042808-MU
Other Names:
R5237 (G1), C57BL/6J-MtgxR5237Btlr
Major Collection:

Gene Information

Agtrap
Name: angiotensin II, type I receptor-associated protein
Synonyms: D4Wsu124e, 3300002E14Rik, Atrap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11610
Homologene: 7621
Zfp934
Name: zinc finger protein 934
Synonyms: 6720457D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 77117
VEGA: 13
Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 77595
Homologene: 28122
Tfg
Name: Trk-fused gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 21787
Homologene: 4426
Sin3b
Name: transcriptional regulator, SIN3B (yeast)
Synonyms: 2810430C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 20467
Homologene: 81810
Setx
Name: senataxin
Synonyms: A930037J23Rik, Als4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269254
HGNC: HGNC:445
Homologene: 41003
Hsf2
Name: heat shock factor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 15500
VEGA: 10
HGNC: HGNC:5225
Homologene: 37931
Papola
Name: poly (A) polymerase alpha
Synonyms: Plap, PapIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 18789
Homologene: 23389
Rsrc2
Name: arginine/serine-rich coiled-coil 2
Synonyms: 1500011J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 208606
Homologene: 133892
Cyb5a
Name: cytochrome b5 type A (microsomal)
Synonyms: Cyb5, 0610009N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 109672
HGNC: HGNC:2570
Homologene: 41475
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, mitosin, Lek1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Cog7
Name: component of oligomeric golgi complex 7
Synonyms: 5630400E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233824
Homologene: 33431
Ezh1
Name: enhancer of zeste 1 polycomb repressive complex 2 subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14055
HGNC: HGNC:3526
Homologene: 20458
Slitrk5
Name: SLIT and NTRK-like family, member 5
Synonyms: 2610019D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 75409
VEGA: 14
Homologene: 9193
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, Dnahc7a, LOC381341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 627872
Homologene: 41287
Adcy1
Name: adenylate cyclase 1
Synonyms: AC1, I-AC, D11Bwg1392e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 432530
HGNC: HGNC:232
Homologene: 41419
Il15ra
Name: interleukin 15 receptor, alpha chain
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16169
HGNC: HGNC:5978
Homologene: 1650
Rpl7
Name: ribosomal protein L7
Synonyms: Rpl7a, Surf-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 19989
Homologene: 87772
Tnc
Name: tenascin C
Synonyms: hexabrachion, Hxb, cytotactin, tenascin-C, C130033P17Rik, TN-C, TN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 21923
HGNC: HGNC:5318
Homologene: 55636
Adamtsl1
Name: ADAMTS-like 1
Synonyms: 6720426B09Rik, 5930437A14Rik, punctin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 77739
Homologene: 64642
Map2
Name: microtubule-associated protein 2
Synonyms: repro4, Mtap2, G1-397-34, MAP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Pon2
Name: paraoxonase 2
Synonyms: 6330405I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330260
HGNC: HGNC:9205
Homologene: 385
Serpina10
Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
Synonyms: PZI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217847
Homologene: 9414
Gata4
Name: GATA binding protein 4
Synonyms: Gata-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 14463
HGNC: HGNC:4173
Homologene: 1551
H2-T23
Name: histocompatibility 2, T region locus 23
Synonyms: T18c, T23b, Qed-1, Qa1, Qa-1, 37b, H-2T23, T18c(37), T23d, 37c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 15040
HGNC: HGNC:4962
Homologene: 134018
Cpne5
Name: copine V
Synonyms: A830083G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 240058
HGNC: HGNC:2318
Homologene: 23266
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 665700
Homologene: 90772
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Xylt2
Name: xylosyltransferase II
Synonyms: E030002B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217119
Homologene: 23349
Large2
Name: LARGE xylosyl- and glucuronyltransferase 2
Synonyms: 5730485C17Rik, Gyltl1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228366
Homologene: 27362
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225997
VEGA: 19
Homologene: 9767
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Tesk1
Name: testis specific protein kinase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 21754
Homologene: 4577
Cul9
Name: cullin 9
Synonyms: 1810035I07Rik, Parc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78309
Homologene: 56696
Trim69
Name: tripartite motif-containing 69
Synonyms: 4921519C19Rik, Trif, Rnf36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 70928
Homologene: 18827
Olfr921
Name: olfactory receptor 921
Synonyms: GA_x6K02T2PVTD-32478047-32478988, MOR165-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258778
VEGA: 9
Homologene: 128138
Stard9
Name: START domain containing 9
Synonyms: E230025N21Rik, 4831403C07Rik, Kif16a, N-3 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 668880
Homologene: 130712
Aadacl4
Name: arylacetamide deacetylase like 4
Synonyms: Gm13177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 435815
Homologene: 82530
Adamts3
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
Synonyms: 1100001H14Rik, 6330442E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330119
HGNC: HGNC:219
Homologene: 8596
Gcc1
Name: golgi coiled coil 1
Synonyms: 4932417P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 74375
Homologene: 11567
Srgap1
Name: SLIT-ROBO Rho GTPase activating protein 1
Synonyms: 4930572H05Rik, Arhgap13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 117600
Homologene: 56898
Col4a1
Name: collagen, type IV, alpha 1
Synonyms: Del(8)Bru44H, Raw, Col4a-1, alpha1(IV) collagen, Svc, Del(8)44H, Bru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12826
HGNC: HGNC:2202
Homologene: 20437
Vmn2r84
Name: vomeronasal 2, receptor 84
Synonyms: EG625068
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 625068
Homologene: 129606
Mfsd6l
Name: major facilitator superfamily domain containing 6-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 215723
Homologene: 17128
Olfr796
Name: olfactory receptor 796
Synonyms: GA_x6K02T2PULF-11287099-11286167, MOR269-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258933
Homologene: 17439
Atg2a
Name: autophagy related 2A
Synonyms: 1810013C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 329015
Homologene: 86985
Plch2
Name: phospholipase C, eta 2
Synonyms: A930027K05Rik, Plcl4, PLCeta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269615
Homologene: 85172
Cpeb2
Name: cytoplasmic polyadenylation element binding protein 2
Synonyms: A630055H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231207
Homologene: 17995
Ankrd24
Name: ankyrin repeat domain 24
Synonyms: 5730519E19Rik, 4631433D01Rik, D10Bur2e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70615
Homologene: 49885
Ccdc40
Name: coiled-coil domain containing 40
Synonyms: B930008I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 207607
Homologene: 27890
Phldb2
Name: pleckstrin homology like domain, family B, member 2
Synonyms: LL5beta, LL5b, C820004H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 208177
Homologene: 17100
Mymk
Name: myomaker, myoblast fusion factor
Synonyms: Tmem8c, 1110002H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66139
Homologene: 11925
Pex26
Name: peroxisomal biogenesis factor 26
Synonyms: peroxisome biogenesis factor 26, 4632428M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 74043
Homologene: 9922
Stt3a
Name: STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
Synonyms: Itm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 16430
HGNC: HGNC:6172
Homologene: 40617
Galnt6
Name: polypeptide N-acetylgalactosaminyltransferase 6
Synonyms: GalNAc-T6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 207839
HGNC: HGNC:4128
Homologene: 5218
Wdr35
Name: WD repeat domain 35
Synonyms: 4930459M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 74682
Homologene: 10814
Sv2c
Name: synaptic vesicle glycoprotein 2c
Synonyms: 4930527L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 75209
Homologene: 57152
Selenov
Name: selenoprotein V
Synonyms: BC089491
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 280621
Homologene: 35357
Gm13119
Name: predicted gene 13119
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 433779
Homologene: 83161
Skint11
Name: selection and upkeep of intraepithelial T cells 11
Synonyms: A630098G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230623
Homologene: 136292
Vmn1r6
Name: vomeronasal 1 receptor 6
Synonyms: V1rc20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 171193
Homologene: 128340
Fbxo40
Name: F-box protein 40
Synonyms: 9830003A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 207215
Homologene: 9459
Fcgr2b
Name: Fc receptor, IgG, low affinity IIb
Synonyms: Fc gamma RIIB, Ly-17, LyM-1, FcgRII, Fc[g]RII, FcgammaRIIB, Fcgr2a, Fcr-3, Ly-m20, Fcr-2, Fcgr2, F630109E10Rik, CD32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14130
HGNC: HGNC:3618
Homologene: 2974
Setbp1
Name: SET binding protein 1
Synonyms: Seb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240427
Homologene: 9192
Olfr692
Name: olfactory receptor 692
Synonyms: MOR36-1, GA_x6K02T2PBJ9-7994144-7995106
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258352
Homologene: 64859
Med24
Name: mediator complex subunit 24
Synonyms: 100kDa, D11Ertd307e, DRIP100, Thrap4, R75526, Pparb2, Gse2, Trap100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 23989
Homologene: 40795
Plekho1
Name: pleckstrin homology domain containing, family O member 1
Synonyms: Jza2, 2810052M02Rik, CKIP-1, JZA-20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 67220
Homologene: 9448
Tor4a
Name: torsin family 4, member A
Synonyms: A830007P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227612
Homologene: 17140
Gm5591
Name: predicted gene 5591
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434171
Homologene: 80005
Olfr120
Name: olfactory receptor 120
Synonyms: MOR263-3, GA_x6K02T2PSCP-2184981-2185946
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258624
Homologene: 110622
Efcab9
Name: EF-hand calcium binding domain 9
Synonyms: 1700007I06Rik, 4930403C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69306
Homologene: 12309
Mroh6
Name: maestro heat-like repeat family member 6
Synonyms: Gm19570
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223645
Homologene: 90414
Gm27924
Name: predicted gene, 27924
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 16,102,575 bp
  • A to C, chromosome 1 at 53,447,531 bp
  • A to G, chromosome 1 at 66,439,010 bp
  • A to G, chromosome 1 at 170,968,233 bp
  • A to T, chromosome 1 at 189,659,533 bp
  • A to G, chromosome 2 at 11,733,205 bp
  • T to G, chromosome 2 at 25,194,964 bp
  • T to C, chromosome 2 at 27,062,188 bp
  • C to T, chromosome 2 at 29,146,983 bp
  • T to A, chromosome 2 at 31,414,716 bp
  • A to T, chromosome 2 at 76,811,243 bp
  • T to C, chromosome 2 at 92,367,142 bp
  • A to G, chromosome 2 at 120,699,358 bp
  • A to G, chromosome 2 at 122,173,340 bp
  • A to G, chromosome 3 at 90,180,198 bp
  • A to G, chromosome 3 at 95,995,625 bp
  • T to C, chromosome 4 at 43,447,100 bp
  • G to A, chromosome 4 at 63,962,096 bp
  • T to C, chromosome 4 at 86,385,669 bp
  • A to G, chromosome 4 at 114,244,845 bp
  • G to T, chromosome 4 at 144,362,471 bp
  • G to A, chromosome 4 at 144,623,280 bp
  • A to G, chromosome 4 at 148,082,360 bp
  • A to G, chromosome 4 at 155,010,794 bp
  • G to A, chromosome 5 at 43,285,756 bp
  • A to T, chromosome 5 at 89,775,377 bp
  • T to C, chromosome 5 at 123,739,582 bp
  • A to C, chromosome 6 at 5,265,455 bp
  • A to T, chromosome 6 at 28,420,652 bp
  • A to C, chromosome 6 at 57,003,194 bp
  • T to A, chromosome 6 at 121,185,847 bp
  • T to C, chromosome 7 at 28,288,147 bp
  • T to A, chromosome 7 at 38,522,207 bp
  • A to T, chromosome 7 at 105,369,306 bp
  • A to G, chromosome 7 at 121,951,221 bp
  • G to A, chromosome 8 at 11,245,068 bp
  • A to C, chromosome 8 at 72,733,343 bp
  • T to C, chromosome 9 at 36,765,118 bp
  • C to T, chromosome 9 at 38,775,956 bp
  • T to A, chromosome 9 at 79,700,262 bp
  • C to A, chromosome 10 at 57,506,221 bp
  • C to A, chromosome 10 at 81,642,545 bp
  • A to G, chromosome 10 at 121,807,883 bp
  • A to G, chromosome 10 at 129,607,863 bp
  • A to G, chromosome 10 at 130,385,994 bp
  • A to T, chromosome 11 at 7,149,553 bp
  • A to T, chromosome 11 at 32,522,832 bp
  • C to A, chromosome 11 at 68,557,270 bp
  • T to C, chromosome 11 at 94,667,127 bp
  • T to C, chromosome 11 at 98,710,783 bp
  • A to G, chromosome 11 at 101,216,993 bp
  • T to C, chromosome 11 at 119,259,976 bp
  • T to C, chromosome 12 at 8,978,639 bp
  • T to A, chromosome 12 at 103,628,816 bp
  • T to C, chromosome 12 at 105,826,960 bp
  • A to G, chromosome 13 at 62,517,838 bp
  • G to A, chromosome 13 at 95,981,883 bp
  • C to T, chromosome 14 at 63,240,626 bp
  • T to A, chromosome 14 at 111,681,686 bp
  • T to C, chromosome 15 at 75,885,991 bp
  • T to A, chromosome 15 at 82,558,006 bp
  • C to A, chromosome 15 at 100,693,393 bp
  • T to C, chromosome 16 at 36,966,082 bp
  • T to C, chromosome 16 at 45,747,886 bp
  • T to A, chromosome 16 at 56,712,708 bp
  • T to G, chromosome 17 at 29,237,618 bp
  • C to T, chromosome 17 at 36,030,366 bp
  • T to A, chromosome 17 at 37,726,377 bp
  • T to C, chromosome 17 at 46,543,467 bp
  • T to A, chromosome 18 at 78,856,975 bp
  • T to G, chromosome 18 at 84,871,564 bp
  • G to T, chromosome 19 at 6,246,814 bp
  • C to T, chromosome 19 at 18,813,464 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5237 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042808-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.