Strain Name:
C57BL/6J-MtgxR5255Btlr/Mmmh
Stock Number:
042826-MU
Citation ID:
RRID:MMRRC_042826-MU
Other Names:
R5255 (G1), C57BL/6J-MtgxR5255Btlr
Major Collection:

Gene Information

Clybl
Name: citrate lyase beta like
Synonyms: Clb, 0610033J05Rik, 2310014M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 69634
VEGA: 14
Homologene: 49925
Syngr1
Name: synaptogyrin 1
Synonyms: p29, Syngr1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20972
Homologene: 3456
Strn4
Name: striatin, calmodulin binding protein 4
Synonyms: zinedin, ZIN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 97387
Homologene: 8378
Esrrg
Name: estrogen-related receptor gamma
Synonyms: Errg, estrogen-related receptor 3, ERR3, NR3B3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26381
HGNC: HGNC:3474
Homologene: 55581
Drd5
Name: dopamine receptor D5
Synonyms: D5R, DRD1b, Gpcr1, Drd1b, Drd-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13492
HGNC: HGNC:3026
Homologene: 20216
Fxr2
Name: fragile X mental retardation, autosomal homolog 2
Synonyms: Fxr2h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 23879
HGNC: HGNC:4024
Homologene: 21014
Cobl
Name: cordon-bleu WH2 repeat
Synonyms: C530045F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12808
Homologene: 9058
Cep170
Name: centrosomal protein 170
Synonyms: A330004A13Rik, 4933426L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545389
Homologene: 22844
Ddx39b
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
Synonyms: 0610030D10Rik, Bat1a, D17H6S81E-1, Bat1, Bat-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 53817
Homologene: 48376
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, Lek1, mitosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Ank3
Name: ankyrin 3, epithelial
Synonyms: 2900054D09Rik, Ank-3, AnkG, Ankyrin-3, Ankyrin-G
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Slitrk6
Name: SLIT and NTRK-like family, member 6
Synonyms: 4832410J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239250
VEGA: 14
Homologene: 12986
Lrpprc
Name: leucine-rich PPR-motif containing
Synonyms: Lrp130, 3110001K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72416
Homologene: 32695
Abr
Name: active BCR-related gene
Synonyms: 6330400K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 109934
HGNC: HGNC:81
Homologene: 11081
Mobp
Name: myelin-associated oligodendrocytic basic protein
Synonyms: MOBP155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17433
HGNC: HGNC:7189
Homologene: 32040
Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Synonyms: Acc1, LOC327983, A530025K05Rik, acetyl-CoA carboxylase, Acac
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 107476
HGNC: HGNC:84
Homologene: 31015
Abcf1
Name: ATP-binding cassette, sub-family F (GCN20), member 1
Synonyms: Abc50, D17Wsu166e, GCN20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224742
HGNC: HGNC:70
Homologene: 849
Arhgef1
Name: Rho guanine nucleotide exchange factor (GEF) 1
Synonyms: Lsc, Lbcl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16801
HGNC: HGNC:681
Homologene: 3454
Acp6
Name: acid phosphatase 6, lysophosphatidic
Synonyms: mPACPL1, ACPL1, 5730559A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66659
Homologene: 41128
Tap1
Name: transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Synonyms: MTP1, Abcb2, TAP, Ham1, PSF-1, RING4, Ham-1, Tap-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21354
HGNC: HGNC:43
Homologene: 495
Kank4
Name: KN motif and ankyrin repeat domains 4
Synonyms: Ankrd38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242553
Homologene: 18244
Zfp12
Name: zinc finger protein 12
Synonyms: Krox-7, Zfp-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231866
Homologene: 65328
Hnrnph1
Name: heterogeneous nuclear ribonucleoprotein H1
Synonyms: E430005G16Rik, Hnrph1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 59013
HGNC: HGNC:5041
Homologene: 31318
Wdr75
Name: WD repeat domain 75
Synonyms: 1300003A18Rik, 2410118I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 73674
Homologene: 32771
Vac14
Name: Vac14 homolog (S. cerevisiae)
Synonyms: D8Wsu151e, Tax1bp2, ingls, Trx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234729
Homologene: 6528
Nceh1
Name: neutral cholesterol ester hydrolase 1
Synonyms: Aadacl1, CPO-BP, mKIAA1363, B230106I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 320024
Homologene: 23251
Siglecg
Name: sialic acid binding Ig-like lectin G
Synonyms: mSiglec-G, A630096C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243958
Homologene: 13228
Tnfrsf25
Name: tumor necrosis factor receptor superfamily, member 25
Synonyms: Tnfrsf12, TRAMP, Wsl, TR3, APO-3, DDR3, WSL-LR, LARD, DR3, WSL-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 85030
Homologene: 13202
Scn1a
Name: sodium channel, voltage-gated, type I, alpha
Synonyms: Nav1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20265
Homologene: 21375
Idh2
Name: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Synonyms: IDPm, Idh-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269951
HGNC: HGNC:5383
Homologene: 37590
Col1a2
Name: collagen, type I, alpha 2
Synonyms: Cola2, Cola-2, Col1a-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12843
HGNC: HGNC:2198
Homologene: 69
Tarbp1
Name: TAR RNA binding protein 1
Synonyms: Gm17296
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212728
Homologene: 38082
Hivep2
Name: human immunodeficiency virus type I enhancer binding protein 2
Synonyms: Shn-2, Schnurri-2, Gm20114, MIBP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 15273
HGNC: HGNC:4921
Homologene: 4900
Ralgps1
Name: Ral GEF with PH domain and SH3 binding motif 1
Synonyms: RALGEF2, 5830418G11Rik, RALGPS1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241308
Homologene: 65163
Ints10
Name: integrator complex subunit 10
Synonyms: 4921521J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 70885
Homologene: 10029
Ahnak2
Name: AHNAK nucleoprotein 2
Synonyms: LOC382643
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 100041194
Homologene: 131081
Acot10
Name: acyl-CoA thioesterase 10
Synonyms: MT-ACT48, p48, Acate3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 64833
VEGA: 15
Homologene: 8206
D430041D05Rik
Name: RIKEN cDNA D430041D05 gene
Synonyms: G2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241589
Homologene: 115928
Slc3a1
Name: solute carrier family 3, member 1
Synonyms: NTAA, D2H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20532
VEGA: 17
Homologene: 37289
Gjd4
Name: gap junction protein, delta 4
Synonyms: Cx39, 9430022F06Rik, connexin 39
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225152
VEGA: 18
Homologene: 17692
Vmn1r218
Name: vomeronasal 1 receptor 218
Synonyms: V1ri5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171256
Homologene: 110880
Phf8-ps
Name: PHD finger protein 8, pseudogene
Synonyms: 4921501E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74042
VEGA: 17
Homologene: 66275
Btn1a1
Name: butyrophilin, subfamily 1, member A1
Synonyms: Btn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 12231
HGNC: HGNC:1135
Homologene: 1312
Olfr1303
Name: olfactory receptor 1303
Synonyms: MOR245-28_p, Olfr276, MOR245-7, GA_x6K02T2Q125-72882187-72881249, MOR245-7, GA_x6K02T2N82Q-3465-3764
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258397
Homologene: 88429
Myo5b
Name: myosin VB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17919
HGNC: HGNC:7603
Homologene: 49481
Slc22a30
Name: solute carrier family 22, member 30
Synonyms: C730048C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 319800
Homologene: 77136
Slc16a5
Name: solute carrier family 16 (monocarboxylic acid transporters), member 5
Synonyms: MCT5, A130015N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217316
Homologene: 20985
Mapkbp1
Name: mitogen-activated protein kinase binding protein 1
Synonyms: Jnkbp1, 2810483F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26390
Homologene: 69109
Elmo3
Name: engulfment and cell motility 3
Synonyms: CED-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234683
Homologene: 23475
Efcab14
Name: EF-hand calcium binding domain 14
Synonyms: 4732418C07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230648
Homologene: 8858
Zswim8
Name: zinc finger SWIM-type containing 8
Synonyms: 2310021P13Rik, 4832404P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268721
VEGA: 14
Homologene: 34313
Ccng2
Name: cyclin G2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12452
HGNC: HGNC:1593
Homologene: 3208
Apbb1ip
Name: amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
Synonyms: Prp48, 9930118P07Rik, proline-rich protein 48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 54519
Homologene: 32434
Slc16a11
Name: solute carrier family 16 (monocarboxylic acid transporters), member 11
Synonyms: MNCb-2717
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216867
Homologene: 27409
Akr1c6
Name: aldo-keto reductase family 1, member C6
Synonyms: 3alpha-HSD, Akr1c1, estradiol 17-beta-dehydrogenase (A-specific), Hsd17b5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 83702
HGNC: HGNC:387
Homologene: 84695
Rnls
Name: renalase, FAD-dependent amine oxidase
Synonyms: 6530404N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67795
Homologene: 41254
Mpst
Name: mercaptopyruvate sulfurtransferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 246221
VEGA: 15
HGNC: HGNC:7223
Homologene: 31942
B230307C23Rik
Name: RIKEN cDNA B230307C23 gene
Synonyms: EG245305
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 245305
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 45,799,117 bp
  • A to G, chromosome 1 at 176,742,468 bp
  • G to A, chromosome 1 at 188,146,358 bp
  • G to A, chromosome 1 at 189,672,627 bp
  • T to A, chromosome 2 at 22,836,055 bp
  • A to T, chromosome 2 at 33,276,159 bp
  • A to T, chromosome 2 at 66,277,669 bp
  • T to C, chromosome 2 at 104,256,600 bp
  • T to C, chromosome 2 at 111,814,178 bp
  • T to C, chromosome 2 at 120,017,254 bp
  • T to C, chromosome 3 at 27,183,139 bp
  • T to C, chromosome 3 at 97,167,996 bp
  • T to C, chromosome 4 at 98,778,972 bp
  • A to T, chromosome 4 at 115,746,588 bp
  • C to A, chromosome 4 at 152,116,490 bp
  • T to G, chromosome 5 at 38,319,967 bp
  • T to A, chromosome 5 at 93,273,325 bp
  • A to T, chromosome 5 at 143,240,379 bp
  • A to G, chromosome 6 at 4,522,462 bp
  • A to G, chromosome 7 at 16,838,648 bp
  • G to A, chromosome 7 at 24,925,022 bp
  • T to C, chromosome 7 at 43,410,501 bp
  • GGGCCAG to GG, chromosome 7 at 80,098,348 bp
  • T to C, chromosome 8 at 68,793,972 bp
  • C to T, chromosome 8 at 105,307,353 bp
  • T to A, chromosome 8 at 110,634,329 bp
  • T to G, chromosome 8 at 126,428,970 bp
  • A to G, chromosome 9 at 120,168,353 bp
  • T to A, chromosome 10 at 14,131,267 bp
  • T to C, chromosome 10 at 69,885,200 bp
  • A to G, chromosome 11 at 12,375,825 bp
  • A to G, chromosome 11 at 50,385,899 bp
  • A to G, chromosome 11 at 69,643,841 bp
  • T to A, chromosome 11 at 70,215,432 bp
  • T to A, chromosome 11 at 76,455,683 bp
  • T to A, chromosome 11 at 84,311,307 bp
  • A to G, chromosome 11 at 115,462,675 bp
  • G to A, chromosome 12 at 112,773,378 bp
  • A to T, chromosome 13 at 4,447,019 bp
  • A to T, chromosome 13 at 23,136,711 bp
  • A to G, chromosome 13 at 23,464,154 bp
  • T to A, chromosome 14 at 20,721,651 bp
  • A to T, chromosome 14 at 110,749,753 bp
  • A to C, chromosome 14 at 122,384,279 bp
  • A to G, chromosome 15 at 20,665,932 bp
  • A to G, chromosome 15 at 78,410,508 bp
  • A to G, chromosome 15 at 80,091,446 bp
  • T to A, chromosome 16 at 98,008,691 bp
  • A to T, chromosome 17 at 33,066,765 bp
  • T to C, chromosome 17 at 34,188,329 bp
  • C to T, chromosome 17 at 35,244,251 bp
  • A to T, chromosome 17 at 35,959,737 bp
  • T to C, chromosome 17 at 84,770,336 bp
  • A to T, chromosome 17 at 85,028,453 bp
  • T to C, chromosome 18 at 9,280,613 bp
  • A to T, chromosome 18 at 74,662,670 bp
  • G to A, chromosome 19 at 8,344,393 bp
  • A to G, chromosome 19 at 33,382,423 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5255 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042826-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.