Strain Name:
C57BL/6J-MtgxR5313Btlr/Mmmh
Stock Number:
042896-MU
Citation ID:
RRID:MMRRC_042896-MU
Other Names:
R5313 (G1), C57BL/6J-MtgxR5313Btlr
Major Collection:

Gene Information

Arhgef18
Name: rho/rac guanine nucleotide exchange factor (GEF) 18
Synonyms: A430078G23Rik, D030053O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 319493
Homologene: 32254
Armh3
Name: armadillo-like helical domain containing 3
Synonyms: 9130011E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 71617
VEGA: 19
Homologene: 15843
Snd1
Name: staphylococcal nuclease and tudor domain containing 1
Synonyms: p100 co-activator, Tudor-SN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 56463
Homologene: 8665
Adgrl2
Name: adhesion G protein-coupled receptor L2
Synonyms: Lphh1, Lec1, Lphn2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99633
Homologene: 22712
Prpf4b
Name: pre-mRNA processing factor 4B
Synonyms: Prp4, Prp4k, Prpk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 19134
VEGA: 13
Homologene: 134085
Tut4
Name: terminal uridylyl transferase 4
Synonyms: 6030404K05Rik, 9230115F04Rik, Zcchc11, Tent3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230594
Homologene: 35279
Slc18a2
Name: solute carrier family 18 (vesicular monoamine), member 2
Synonyms: 1110037L13Rik, Vmat2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 214084
VEGA: 19
Homologene: 2298
Arhgef17
Name: Rho guanine nucleotide exchange factor (GEF) 17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 207212
Homologene: 129601
Pabpc1
Name: poly(A) binding protein, cytoplasmic 1
Synonyms: Pabpl1, Pabp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18458
HGNC: HGNC:8554
Homologene: 37638
Fgfr2
Name: fibroblast growth factor receptor 2
Synonyms: Fgfr-2, Fgfr7, Bek, KGFRTr, svs, Fgfr-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14183
HGNC: HGNC:3689
Homologene: 22566
Adgra3
Name: adhesion G protein-coupled receptor A3
Synonyms: Gpr125, 3830613O22Rik, Tem5-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70693
Homologene: 19235
Map2
Name: microtubule-associated protein 2
Synonyms: repro4, Mtap2, G1-397-34, MAP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Arhgef2
Name: rho/rac guanine nucleotide exchange factor (GEF) 2
Synonyms: GEF-H1, P40, Lfc, Lbcl1, GEFH1, LFP40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 16800
HGNC: HGNC:682
Homologene: 3468
Adam19
Name: a disintegrin and metallopeptidase domain 19 (meltrin beta)
Synonyms: Mltnb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11492
HGNC: HGNC:197
Homologene: 74925
Ctsc
Name: cathepsin C
Synonyms: DPPI, dipeptidylpeptidase 1, DPP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13032
HGNC: HGNC:2528
Homologene: 1373
Fam135a
Name: family with sequence similarity 135, member A
Synonyms: 4921533L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68187
Homologene: 32665
Cdh6
Name: cadherin 6
Synonyms: K-cadherin, cad6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12563
VEGA: 15
HGNC: HGNC:1765
Homologene: 21027
Zbtb7b
Name: zinc finger and BTB domain containing 7B
Synonyms: c-Krox, Zfp67, Thpok
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 22724
Homologene: 7605
Ism2
Name: isthmin 2
Synonyms: LOC217738, Thsd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217738
Homologene: 83509
Cdc42bpa
Name: CDC42 binding protein kinase alpha
Synonyms: A930014J19Rik, DMPK-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226751
HGNC: HGNC:1737
Homologene: 55765
Fstl5
Name: follistatin-like 5
Synonyms: 9130207J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 213262
Homologene: 10584
Glp2r
Name: glucagon-like peptide 2 receptor
Synonyms: GLP-2, 9530092J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 93896
HGNC: HGNC:4325
Homologene: 3132
Cacna1d
Name: calcium channel, voltage-dependent, L type, alpha 1D subunit
Synonyms: C79217, Cav1.3alpha1, 8430418G19Rik, Cchl1a2, Cacnl1a2, D-LTCC, Cchl1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 12289
VEGA: 14
HGNC: HGNC:1391
Homologene: 578
Ephb6
Name: Eph receptor B6
Synonyms: Cekl, Mep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 13848
HGNC: HGNC:3396
Homologene: 20940
4930402H24Rik
Name: RIKEN cDNA 4930402H24 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228602
Homologene: 12623
Mfsd6
Name: major facilitator superfamily domain containing 6
Synonyms: 9630025I22Rik, 2210010L05Rik, MMR2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98682
Homologene: 9784
Fam234b
Name: family with sequence similarity 234, member B
Synonyms: 8430419L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 74525
Homologene: 12572
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Gm7455, Col6a5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 665033
Homologene: 122792
Slc34a2
Name: solute carrier family 34 (sodium phosphate), member 2
Synonyms: Npt2b, D5Ertd227e, type IIb Na/Picotransporter, NaPi-2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20531
Homologene: 2297
Phykpl
Name: 5-phosphohydroxy-L-lysine phospholyase
Synonyms: Agxt2l2, 2900006B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72947
Homologene: 75268
Sntb1
Name: syntrophin, basic 1
Synonyms: 59-1 DAP, beta1-Syntrophin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 20649
Homologene: 9618
Olfr1329
Name: olfactory receptor 1329
Synonyms: MOR259-2, GA_x6K02T2QD9B-18619941-18620882
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 258214
Homologene: 79401
Olfr1228
Name: olfactory receptor 1228
Synonyms: MOR233-1, GA_x6K02T2Q125-50696209-50695274
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258973
Homologene: 74217
Cpox
Name: coproporphyrinogen oxidase
Synonyms: nct, clone 560, cac, Cpo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12892
VEGA: 16
HGNC: HGNC:2321
Homologene: 76
Usp17la
Name: ubiquitin specific peptidase 17-like A
Synonyms: Dub1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13531
Homologene: 131315
Olfr791
Name: olfactory receptor 791
Synonyms: MOR114-1, GA_x6K02T2PULF-11205096-11206034
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258932
Homologene: 71950
Timm10b
Name: translocase of inner mitochondrial membrane 10B
Synonyms: FxC1, Fracture Callus 1, Tim9b, Tim10b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14356
HGNC: HGNC:4022
Homologene: 8142
Ido1
Name: indoleamine 2,3-dioxygenase 1
Synonyms: Ido, Indo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 15930
HGNC: HGNC:6059
Homologene: 48082
Gpr85
Name: G protein-coupled receptor 85
Synonyms: 2900026B03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 64450
HGNC: HGNC:4536
Homologene: 10355
Sept8
Name: septin 8
Synonyms: Sepl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20362
Homologene: 57205
Olfr1466
Name: olfactory receptor 1466
Synonyms: MOR202-12, GA_x6K02T2RE5P-3672907-3673839
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258689
Homologene: 133677
Tmprss11a
Name: transmembrane protease, serine 11a
Synonyms: LOC194597
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 194597
Homologene: 62723
Ppargc1a
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Synonyms: Pgc-1alpha, PPAR Gamma Coactivator-1, Pgc-1alphaa, Pgc1, Pgco1, Gm11133, A830037N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19017
HGNC: HGNC:9237
Homologene: 7485
Gm13270
Name: predicted gene 13270
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 105244084
Mrgprb13
Name: MAS-related GPR, member B13
Synonyms: MrgB13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 620137
Homologene: 83620
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 24,028,585 bp
  • A to C, chromosome 1 at 52,658,651 bp
  • A to G, chromosome 1 at 66,425,379 bp
  • T to G, chromosome 1 at 180,084,433 bp
  • G to T, chromosome 2 at 13,320,054 bp
  • C to T, chromosome 2 at 89,249,377 bp
  • C to T, chromosome 2 at 130,709,268 bp
  • A to T, chromosome 3 at 76,593,505 bp
  • A to G, chromosome 3 at 88,607,927 bp
  • G to T, chromosome 3 at 89,381,319 bp
  • A to G, chromosome 3 at 148,823,713 bp
  • T to C, chromosome 4 at 108,549,400 bp
  • A to G, chromosome 4 at 118,916,798 bp
  • A to T, chromosome 5 at 49,961,309 bp
  • A to G, chromosome 5 at 51,458,239 bp
  • A to T, chromosome 5 at 53,069,339 bp
  • A to T, chromosome 5 at 86,411,815 bp
  • A to T, chromosome 6 at 13,836,302 bp
  • C to A, chromosome 6 at 28,668,601 bp
  • A to T, chromosome 6 at 41,616,793 bp
  • T to A, chromosome 6 at 135,209,187 bp
  • A to T, chromosome 7 at 48,311,916 bp
  • T to C, chromosome 7 at 88,309,553 bp
  • A to C, chromosome 7 at 100,928,924 bp
  • T to A, chromosome 7 at 104,861,250 bp
  • T to C, chromosome 7 at 105,641,080 bp
  • A to T, chromosome 7 at 130,241,240 bp
  • A to G, chromosome 8 at 3,451,629 bp
  • A to C, chromosome 8 at 24,587,778 bp
  • T to G, chromosome 9 at 105,945,544 bp
  • C to T, chromosome 10 at 129,527,081 bp
  • T to C, chromosome 11 at 46,131,776 bp
  • T to A, chromosome 11 at 51,599,505 bp
  • C to T, chromosome 11 at 53,535,982 bp
  • T to C, chromosome 11 at 67,757,531 bp
  • G to A, chromosome 12 at 87,279,762 bp
  • T to C, chromosome 13 at 34,894,549 bp
  • A to C, chromosome 14 at 30,346,841 bp
  • T to A, chromosome 15 at 13,034,637 bp
  • T to C, chromosome 15 at 36,597,518 bp
  • C to G, chromosome 15 at 55,642,795 bp
  • T to A, chromosome 16 at 58,677,948 bp
  • G to A, chromosome 19 at 13,342,065 bp
  • G to A, chromosome 19 at 45,818,975 bp
  • A to G, chromosome 19 at 59,293,843 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5313 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042896-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.