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Strain Name:
C57BL/6J-MtgxR5372Btlr/Mmmh
Stock Number:
042948-MU
Citation ID:
RRID:MMRRC_042948-MU
Other Names:
R5372 (G1), C57BL/6J-MtgxR5372Btlr
Major Collection:

Strain Information

Slc12a6
Name: solute carrier family 12, member 6
Synonyms: KCC3, gaxp
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 107723
Homologene: 21069
Cdk17
Name: cyclin dependent kinase 17
Synonyms: 6430598J10Rik, Pctk2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237459
VEGA: 10
HGNC: HGNC:8750
Homologene: 55666
Otx1
Name: orthodenticle homeobox 1
Synonyms: A730044F23Rik, jv
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18423
HGNC: HGNC:8521
Homologene: 7875
Gad2
Name: glutamic acid decarboxylase 2
Synonyms: GAD65, Gad-2, 6330404F12Rik, GAD(65)
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14417
HGNC: HGNC:4093
Homologene: 20223
Fgd4
Name: FYVE, RhoGEF and PH domain containing 4
Synonyms: Frabin-gamma, Frabin-beta, Frabin-alpha, Frabin, 9330209B17Rik, ZFYVE6
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224014
Homologene: 26727
Rgs3
Name: regulator of G-protein signaling 3
Synonyms: 4930506N09Rik, PDZ-RGS3, C2pa, RGS3S, C2PA-RGS3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 50780
HGNC: HGNC:9999
Homologene: 32440
Slk
Name: STE20-like kinase
Synonyms: 9A2, mSLK, Etk4, SLK, Stk2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20874
Homologene: 22515
Ptpn12
Name: protein tyrosine phosphatase, non-receptor type 12
Synonyms: P19-PTP, PTP-PEST, PTP-P19
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19248
HGNC: HGNC:9645
Homologene: 37691
Papola
Name: poly (A) polymerase alpha
Synonyms: Plap, PapIII
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18789
Homologene: 23389
Dctn1
Name: dynactin 1
Synonyms: Glued, p150, p150glued
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13191
HGNC: HGNC:2711
Homologene: 3011
Pkn2
Name: protein kinase N2
Synonyms: PRK2, 6030436C20Rik, Stk7, Prkcl2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109333
HGNC: HGNC:9406
Homologene: 2054
Tacc2
Name: transforming, acidic coiled-coil containing protein 2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57752
Homologene: 5087
Clcn7
Name: chloride channel, voltage-sensitive 7
Synonyms: ClC-7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 26373
HGNC: HGNC:2025
Homologene: 56546
Opa1
Name: OPA1, mitochondrial dynamin like GTPase
Synonyms: 1200011N24Rik, lilr3, optic atrophy 1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74143
HGNC: HGNC:8140
Homologene: 14618
Map3k11
Name: mitogen-activated protein kinase kinase kinase 11
Synonyms: Mlk3, 2610017K16Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 26403
VEGA: 19
HGNC: HGNC:6850
Homologene: 37618
Ep300
Name: E1A binding protein p300
Synonyms: p300, KAT3B
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328572
HGNC: HGNC:3373
Homologene: 1094
Tmem135
Name: transmembrane protein 135
Synonyms: 2810439K08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72759
Homologene: 11295
Syt7
Name: synaptotagmin VII
Synonyms: B230112P13Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 54525
VEGA: 19
Homologene: 20889
Stard5
Name: StAR related lipid transfer domain containing 5
Synonyms: 18B7-T7(GS), 2310058G22Rik, D7Ertd152e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 170460
Homologene: 11346
Smc6
Name: structural maintenance of chromosomes 6
Synonyms: 2810489L22Rik, 3830418C19Rik, Smc6l1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 67241
VEGA: 12
Homologene: 41575
Dgcr2
Name: DiGeorge syndrome critical region gene 2
Synonyms: Dgcr2, Idd, Lan, Sez12, DGS-C, Dgsc, 9930034O06Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13356
HGNC: HGNC:2845
Homologene: 31292
Yars2
Name: tyrosyl-tRNA synthetase 2 (mitochondrial)
Synonyms: 2210023C10Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70120
Homologene: 7097
Nxpe2
Name: neurexophilin and PC-esterase domain family, member 2
Synonyms: 4432416J03Rik, Fam55b
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 78252
Homologene: 87072
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: DHC1b, DHC2, 4432416O06Rik, D330044F14Rik, D030010H02Rik, Dnchc2, b2b414Clo, m407Asp, m152Asp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Khsrp
Name: KH-type splicing regulatory protein
Synonyms: 6330409F21Rik, KSRP
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16549
VEGA: 17
HGNC: HGNC:6316
Homologene: 2734
Wdr4
Name: WD repeat domain 4
Synonyms: D530049K22Rik, Wh
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 57773
Homologene: 32422
Nup54
Name: nucleoporin 54
Synonyms: 3110079L04Rik, 54kDa
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269113
Homologene: 41169
Ppp1r21
Name: protein phosphatase 1, regulatory subunit 21
Synonyms: 1110018J12Rik, Ccdc128, Klraq1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 73825
Homologene: 44811
Uggt1
Name: UDP-glucose glycoprotein glucosyltransferase 1
Synonyms: A930007H10Rik, C820010P03Rik, 0910001L17Rik, Ugcgl1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 320011
Homologene: 10586
Tspan12
Name: tetraspanin 12
Synonyms: Tm4sf12
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 269831
Homologene: 8212
Srcap
Name: Snf2-related CREBBP activator protein
Synonyms: F630004O05Rik, B930091H02Rik, D030022P06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100043597
Homologene: 38213
Sox6
Name: SRY (sex determining region Y)-box 6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20679
Homologene: 22631
Hormad1
Name: HORMA domain containing 1
Synonyms: 4921522K05Rik, Nohma
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67981
Homologene: 69415
Cdc42bpa
Name: CDC42 binding protein kinase alpha
Synonyms: DMPK-like, A930014J19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226751
HGNC: HGNC:1737
Homologene: 55765
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Abca4
Name: ATP-binding cassette, sub-family A member 4
Synonyms: Rim protein, RmP, Abc10, D430003I15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11304
HGNC: HGNC:34
Homologene: 298
Adgrb3
Name: adhesion G protein-coupled receptor B3
Synonyms: A830096D10Rik, Bai3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210933
HGNC: HGNC:945
Homologene: 1289
Hephl1
Name: hephaestin-like 1
Synonyms: LOC244698, Zp, zyklopen, thd, cw
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244698
Homologene: 9112
Magi2
Name: membrane associated guanylate kinase, WW and PDZ domain containing 2
Synonyms: S-SCAM, Acvrinp1, Magi-2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 50791
Homologene: 8189
Polr2g
Name: polymerase (RNA) II (DNA directed) polypeptide G
Synonyms: RBP7, 2410046K11Rik, A230108L04Rik, Rpo2-7l
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 67710
VEGA: 19
HGNC: HGNC:9194
Homologene: 2019
Snrk
Name: SNF related kinase
Synonyms: SNRK, 2010012F07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20623
Homologene: 9797
Nynrin
Name: NYN domain and retroviral integrase containing
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 277154
VEGA: 14
Homologene: 19483
Brinp3
Name: bone morphogenetic protein/retinoic acid inducible neural specific 3
Synonyms: B830045N13Rik, Fam5c
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 215378
Homologene: 17786
Scube3
Name: signal peptide, CUB domain, EGF-like 3
Synonyms: D030038I21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268935
Homologene: 65059
Clca3a2
Name: chloride channel accessory 3A2
Synonyms: Clca2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80797
HGNC: HGNC:2017
Homologene: 77224
Rasal3
Name: RAS protein activator like 3
Synonyms: A430107D22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320484
Homologene: 18901
Cacna1b
Name: calcium channel, voltage-dependent, N type, alpha 1B subunit
Synonyms: Cchn1a, alpha(1B), Cav2.2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12287
HGNC: HGNC:1389
Homologene: 20184
Heca
Name: hdc homolog, cell cycle regulator
Synonyms: LOC380629
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 380629
VEGA: 10
Homologene: 32300
Supv3l1
Name: suppressor of var1, 3-like 1 (S. cerevisiae)
Synonyms: 6330443E10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 338359
Homologene: 2386
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 435626
Homologene: 52359
Anxa8
Name: annexin A8
Synonyms: Anx8
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 11752
HGNC: HGNC:546
Homologene: 20393
Mtus2
Name: microtubule associated tumor suppressor candidate 2
Synonyms: 5730592G18Rik, A730013O20Rik, C130038G02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77521
Homologene: 78141
Atrnl1
Name: attractin like 1
Synonyms: Alp
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226255
VEGA: 19
Homologene: 45809
Abhd12b
Name: abhydrolase domain containing 12B
Synonyms: LOC328121
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 100504285
Homologene: 128243
Ptpre
Name: protein tyrosine phosphatase receptor type E
Synonyms: PTPe, PTPepsilon, RPTPepsilon
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19267
HGNC: HGNC:9669
Homologene: 31387
Vmn2r7
Name: vomeronasal 2, receptor 7
Synonyms: 4933425M15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 319217
Homologene: 129754
Hars2
Name: histidyl-tRNA synthetase 2
Synonyms: HARSR, HO3, 4631412B19Rik, Harsl
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70791
HGNC: HGNC:4817
Homologene: 40819
Ccdc158
Name: coiled-coil domain containing 158
Synonyms: 4932413O14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320696
Homologene: 18560
Arhgap26
Name: Rho GTPase activating protein 26
Synonyms: 1810044B20Rik, 2610010G17Rik, 4933432P15Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 71302
Homologene: 36349
Btbd2
Name: BTB domain containing 2
Synonyms: 2610037C03Rik, 4930512K17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 208198
Homologene: 32365
Clip1
Name: CAP-GLY domain containing linker protein 1
Synonyms: cytoplasmic linker protein 50, Clip50, CLIP-170, 1110007I12Rik, 4631429H07Rik, Rsn, Clip 170, restin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56430
Homologene: 74455
C1ra
Name: complement component 1, r subcomponent A
Synonyms: mC1rA
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 50909
HGNC: HGNC:1246
Homologene: 1313
Fndc1
Name: fibronectin type III domain containing 1
Synonyms: 1110027O12Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68655
Catsperg1
Name: cation channel sperm associated auxiliary subunit gamma 1
Synonyms: A230107C01Rik, Catsperg
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 320225
Homologene: 10915
Ttll3
Name: tubulin tyrosine ligase-like family, member 3
Synonyms: 4833441J24Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101100
Homologene: 134361
Wdfy2
Name: WD repeat and FYVE domain containing 2
Synonyms: B130024L21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268752
VEGA: 14
Homologene: 14188
Fam178b
Name: family with sequence similarity 178, member B
Synonyms: LOC381337, 1700024G10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381337
Homologene: 87288
Cdca7
Name: cell division cycle associated 7
Synonyms: JPO1, 2310021G01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66953
Homologene: 49970
Plcxd3
Name: phosphatidylinositol-specific phospholipase C, X domain containing 3
Synonyms: B130016O10Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239318
Homologene: 45574
Sh2d5
Name: SH2 domain containing 5
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230863
Homologene: 20002
Fam167b
Name: family with sequence similarity 167, member B
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230766
Homologene: 13085
Trim35
Name: tripartite motif-containing 35
Synonyms: Mair, 0710005M05Rik, A430106H13Rik, Hls5
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66854
Homologene: 134331
Rhd
Name: Rh blood group, D antigen
Synonyms: Rh, Rhl1, Rhced
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19746
Homologene: 7918
Adck5
Name: aarF domain containing kinase 5
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 268822
Homologene: 34378
Or14c44
Name: olfactory receptor family 14 subfamily C member 44
Synonyms: GA_x6K02T2NHDJ-9693313-9692378, MOR221-1P, MOR211-8P, MOR221-4, MOR221-1P, Olfr1531-ps1, GA_x6K02T2NHDJ-9695951-9695766, Olfr302, Olfr301
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257958
Homologene: 128067
Ikbip
Name: IKBKB interacting protein
Synonyms: 1700023M03Rik, 1200009F10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67454
Homologene: 12138
Or4f60
Name: olfactory receptor family 4 subfamily F member 60
Synonyms: GA_x6K02T2Q125-73119859-73118924, MOR245-23, Olfr1313
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258257
Homologene: 106834
Apol9b
Name: apolipoprotein L 9b
Synonyms: 2310016F22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 71898
VEGA: 15
Homologene: 77567
Or8a1b
Name: olfactory receptor family 8 subfamily A member 1B
Synonyms: M72, MOR171-3, MOR171-3, GA_x6K02T2PVTD-31389446-31388517, Olfr160
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 80706
HGNC: HGNC:8469
Homologene: 12726
Or56b2j
Name: olfactory receptor family 56 subfamily B member 2J
Synonyms: GA_x6K02T2PBJ9-7331927-7332961, MOR40-12, Olfr663
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257914
Homologene: 133594
Gm38092
Name: predicted gene, 38092
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Zfp383
Name: zinc finger protein 383
Synonyms: 1110003H10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73729
Homologene: 128413
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 25,128,859 bp
  • C to A, chromosome 1 at 36,244,060 bp
  • T to A, chromosome 1 at 36,564,848 bp
  • T to C, chromosome 1 at 74,147,663 bp
  • T to G, chromosome 1 at 146,831,726 bp
  • T to C, chromosome 1 at 180,064,979 bp
  • A to T, chromosome 2 at 22,690,243 bp
  • A to T, chromosome 2 at 24,733,959 bp
  • A to T, chromosome 2 at 72,482,449 bp
  • A to G, chromosome 2 at 112,072,109 bp
  • T to A, chromosome 2 at 112,347,360 bp
  • T to A, chromosome 3 at 64,716,324 bp
  • T to A, chromosome 3 at 95,576,424 bp
  • T to A, chromosome 3 at 122,055,339 bp
  • A to G, chromosome 3 at 142,810,699 bp
  • A to C, chromosome 3 at 144,797,525 bp
  • A to T, chromosome 4 at 62,652,697 bp
  • G to A, chromosome 4 at 88,558,101 bp
  • A to T, chromosome 4 at 101,890,487 bp
  • A to T, chromosome 4 at 129,578,299 bp
  • A to G, chromosome 4 at 134,884,632 bp
  • A to G, chromosome 4 at 138,254,699 bp
  • A to G, chromosome 5 at 20,702,110 bp
  • G to A, chromosome 5 at 20,998,564 bp
  • A to G, chromosome 5 at 92,417,857 bp
  • A to C, chromosome 5 at 92,632,560 bp
  • G to T, chromosome 5 at 123,630,240 bp
  • A to G, chromosome 5 at 148,313,412 bp
  • A to G, chromosome 6 at 21,772,699 bp
  • T to A, chromosome 6 at 83,190,210 bp
  • A to T, chromosome 6 at 113,401,421 bp
  • T to A, chromosome 6 at 124,521,625 bp
  • T to A, chromosome 6 at 132,657,483 bp
  • T to A, chromosome 7 at 29,210,712 bp
  • C to T, chromosome 7 at 29,915,270 bp
  • T to C, chromosome 7 at 42,477,196 bp
  • T to A, chromosome 7 at 83,633,220 bp
  • T to A, chromosome 7 at 86,412,968 bp
  • A to T, chromosome 7 at 89,165,174 bp
  • A to G, chromosome 7 at 104,703,795 bp
  • A to T, chromosome 7 at 115,550,151 bp
  • G to A, chromosome 7 at 127,557,613 bp
  • T to A, chromosome 7 at 130,623,260 bp
  • A to G, chromosome 7 at 135,653,940 bp
  • A to G, chromosome 8 at 123,408,427 bp
  • G to A, chromosome 9 at 7,176,962 bp
  • G to T, chromosome 9 at 15,097,899 bp
  • T to C, chromosome 9 at 37,711,938 bp
  • T to C, chromosome 9 at 48,339,519 bp
  • T to A, chromosome 9 at 79,678,366 bp
  • G to C, chromosome 9 at 122,166,320 bp
  • T to A, chromosome 10 at 17,915,139 bp
  • C to T, chromosome 10 at 62,432,357 bp
  • A to T, chromosome 10 at 80,648,641 bp
  • A to T, chromosome 10 at 91,096,113 bp
  • A to G, chromosome 10 at 93,226,039 bp
  • C to A, chromosome 11 at 21,997,037 bp
  • A to G, chromosome 12 at 11,282,430 bp
  • A to G, chromosome 12 at 70,181,026 bp
  • A to G, chromosome 12 at 105,827,050 bp
  • G to A, chromosome 14 at 34,093,911 bp
  • A to G, chromosome 14 at 55,868,491 bp
  • T to G, chromosome 14 at 62,954,885 bp
  • T to C, chromosome 14 at 66,297,266 bp
  • G to A, chromosome 15 at 4,574,788 bp
  • A to G, chromosome 15 at 76,594,507 bp
  • A to T, chromosome 15 at 77,735,720 bp
  • A to G, chromosome 15 at 81,636,830 bp
  • T to C, chromosome 16 at 16,303,710 bp
  • A to T, chromosome 16 at 16,484,291 bp
  • T to C, chromosome 16 at 17,872,644 bp
  • A to C, chromosome 16 at 29,586,119 bp
  • C to G, chromosome 17 at 7,765,210 bp
  • T to A, chromosome 17 at 25,157,179 bp
  • G to T, chromosome 17 at 28,152,482 bp
  • T to A, chromosome 17 at 31,510,580 bp
  • T to C, chromosome 17 at 32,391,344 bp
  • T to C, chromosome 17 at 57,024,292 bp
  • A to G, chromosome 17 at 88,550,675 bp
  • T to C, chromosome 18 at 36,790,481 bp
  • A to G, chromosome 18 at 38,642,456 bp
  • T to A, chromosome 19 at 5,690,962 bp
  • T to C, chromosome 19 at 8,797,303 bp
  • G to T, chromosome 19 at 10,426,621 bp
  • A to T, chromosome 19 at 47,625,393 bp
  • A to G, chromosome 19 at 57,755,536 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5372 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042948-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.