Strain Name:
C57BL/6J-MtgxR5467Btlr/Mmmh
Stock Number:
043028-MU
Citation ID:
RRID:MMRRC_043028-MU
Other Names:
R5467 (G1), C57BL/6J-MtgxR5467Btlr
Major Collection:

Gene Information

Slc31a2
Name: solute carrier family 31, member 2
Synonyms: Ctr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 20530
Homologene: 37536
Ylpm1
Name: YLP motif containing 1
Synonyms: ZAP, A930013E17Rik, Zap3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 56531
Homologene: 87707
Clcn6
Name: chloride channel, voltage-sensitive 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 26372
HGNC: HGNC:2024
Homologene: 985
Tnks2
Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Synonyms: 5430432P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 74493
Homologene: 11890
Uhrf1bp1l
Name: UHRF1 (ICBP90) binding protein 1-like
Synonyms: E030041M21Rik, 4930506D01Rik, 2010319N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 75089
VEGA: 10
Homologene: 12590
Actn1
Name: actinin, alpha 1
Synonyms: 3110023F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 109711
VEGA: 12
HGNC: HGNC:163
Homologene: 55553
Bicd1
Name: BICD cargo adaptor 1
Synonyms: B830009D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12121
HGNC: HGNC:1049
Homologene: 37518
Pikfyve
Name: phosphoinositide kinase, FYVE type zinc finger containing
Synonyms: Pip5k3, 5230400C17Rik, PipkIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18711
Homologene: 32115
Trak1
Name: trafficking protein, kinesin binding 1
Synonyms: hyrt, 2310001H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 67095
Homologene: 25103
Dmbt1
Name: deleted in malignant brain tumors 1
Synonyms: gp300, Crpd, hensin, ebnerin, CRP-[a], vomeroglandin, CRP-[b], MUCLIN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12945
HGNC: HGNC:2926
Homologene: 68990
Ppp4r3a
Name: protein phosphatase 4 regulatory subunit 3A
Synonyms: Smek1, 1110034C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68734
VEGA: 12
Homologene: 69510
Pank2
Name: pantothenate kinase 2
Synonyms: 4933409I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74450
Homologene: 65126
Rb1
Name: RB transcriptional corepressor 1
Synonyms: retinoblastoma 1, Rb-1, pRb, Rb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19645
HGNC: HGNC:9884
Homologene: 272
Cwc22
Name: CWC22 spliceosome-associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 80744
Homologene: 6048
D430042O09Rik
Name: RIKEN cDNA D430042O09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233865
Homologene: 45841
Dusp27
Name: dual specificity phosphatase 27 (putative)
Synonyms: C130085G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240892
Homologene: 18949
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
Atp7b
Name: ATPase, Cu++ transporting, beta polypeptide
Synonyms: Wilson protein, WND, Atp7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11979
HGNC: HGNC:870
Homologene: 20063
Farp1
Name: FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
Synonyms: Cdep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 223254
HGNC: HGNC:3591
Homologene: 38098
Gm884
Name: predicted gene 884
Synonyms: LOC380730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380730
Homologene: 134511
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: E130113P14Rik, bl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231470
Homologene: 23516
Eml3
Name: echinoderm microtubule associated protein like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225898
VEGA: 19
Homologene: 27044
Pcdhb22
Name: protocadherin beta 22
Synonyms: Pcdhb15, PcdhbV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93893
HGNC: HGNC:8686
Homologene: 113752
Kcnh2
Name: potassium voltage-gated channel, subfamily H (eag-related), member 2
Synonyms: merg1a, merg1b, Lqt2, ether a go-go related, LQT, M-erg, ERG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16511
HGNC: HGNC:6251
Homologene: 201
Gns
Name: glucosamine (N-acetyl)-6-sulfatase
Synonyms: G6S, 2610016K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 75612
VEGA: 10
HGNC: HGNC:4422
Homologene: 1568
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: Mll2, Mll4, C430014K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
Synonyms: flamingo, Fmi1, Adgrc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 107934
HGNC: HGNC:3230
Homologene: 1077
Olfr108
Name: olfactory receptor 108
Synonyms: MOR156-5, GA_x6K02T2PSCP-1893605-1894534
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258457
Homologene: 44985
Sntb1
Name: syntrophin, basic 1
Synonyms: 59-1 DAP, beta1-Syntrophin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 20649
Homologene: 9618
Olfr935
Name: olfactory receptor 935
Synonyms: GA_x6K02T2PVTD-32691280-32690354, MOR171-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258741
VEGA: 9
Homologene: 133683
Prl5a1
Name: prolactin family 5, subfamily a, member 1
Synonyms: D13Wsu14e, 1600013P04Rik, Prlpl, PLP-L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 28078
Homologene: 11378
Skida1
Name: SKI/DACH domain containing 1
Synonyms: 5730507N06Rik, 2810030E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 72668
Homologene: 66327
Usp21
Name: ubiquitin specific peptidase 21
Synonyms: W53272, Usp16, ESTM28, Usp23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 30941
Homologene: 56572
Olfr1428
Name: olfactory receptor 1428
Synonyms: GA_x6K02T2RE5P-2468394-2467450, MOR239-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258673
Homologene: 17339
Ndst1
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
Synonyms: Hsst, b2b2230Clo, 1200015G06Rik, Ndst-1, glucosaminyl N-deacetylase/N-sulfotransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 15531
VEGA: 18
HGNC: HGNC:7680
Homologene: 20386
Olfr981
Name: olfactory receptor 981
Synonyms: GA_x6K02T2PVTD-33720892-33721824, MOR223-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258283
VEGA: 9
Homologene: 64849
Olfr1466
Name: olfactory receptor 1466
Synonyms: MOR202-12, GA_x6K02T2RE5P-3672907-3673839
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258689
Homologene: 133677
Sh3tc2
Name: SH3 domain and tetratricopeptide repeats 2
Synonyms: D430044G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225608
VEGA: 18
Homologene: 11596
Elovl7
Name: ELOVL family member 7, elongation of long chain fatty acids (yeast)
Synonyms: 9130013K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 74559
VEGA: 13
Homologene: 23672
Zfp703
Name: zinc finger protein 703
Synonyms: Zeppo1, Csmn1, End2, 1110032O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 353310
Homologene: 81391
Aloxe3
Name: arachidonate lipoxygenase 3
Synonyms: e-LOX-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 23801
Homologene: 8013
Arpc5l
Name: actin related protein 2/3 complex, subunit 5-like
Synonyms: ARC16-2, 2010015J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74192
Homologene: 36463
Trav13n-4
Name: T cell receptor alpha variable 13N-4
Synonyms: Gm10907, ENSMUSG00000072517
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 100126460
Dnase1l1
Name: deoxyribonuclease 1-like 1
Synonyms: G4.8, Dnase1ll, Dnl1ll, 2310005K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 69537
HGNC: HGNC:2957
Homologene: 4896
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 65,252,495 bp
  • C to A, chromosome 1 at 166,112,030 bp
  • A to G, chromosome 1 at 171,283,133 bp
  • T to C, chromosome 2 at 18,046,112 bp
  • T to C, chromosome 2 at 39,013,739 bp
  • ATCTCTCTCTCTCTCTCT to ATCTCTCTCTCTCTCT, chromosome 2 at 77,929,459 bp
  • T to C, chromosome 2 at 131,282,643 bp
  • A to G, chromosome 4 at 62,292,687 bp
  • A to T, chromosome 4 at 148,017,636 bp
  • A to T, chromosome 5 at 24,326,767 bp
  • A to T, chromosome 5 at 96,780,053 bp
  • T to C, chromosome 6 at 149,550,341 bp
  • T to C, chromosome 7 at 125,843,355 bp
  • C to A, chromosome 7 at 131,040,993 bp
  • T to C, chromosome 7 at 141,636,535 bp
  • G to A, chromosome 8 at 22,011,554 bp
  • C to T, chromosome 8 at 26,979,205 bp
  • T to C, chromosome 9 at 38,994,904 bp
  • G to T, chromosome 9 at 40,022,437 bp
  • A to T, chromosome 9 at 108,828,637 bp
  • A to G, chromosome 9 at 121,446,798 bp
  • G to T, chromosome 10 at 89,805,099 bp
  • T to C, chromosome 10 at 121,391,446 bp
  • C to T, chromosome 11 at 69,142,235 bp
  • G to T, chromosome 11 at 103,603,265 bp
  • A to G, chromosome 12 at 80,176,217 bp
  • T to C, chromosome 12 at 84,996,859 bp
  • T to C, chromosome 12 at 101,043,470 bp
  • A to T, chromosome 13 at 28,150,011 bp
  • T to C, chromosome 13 at 108,279,622 bp
  • T to A, chromosome 14 at 53,363,846 bp
  • T to C, chromosome 14 at 73,211,620 bp
  • C to T, chromosome 14 at 121,235,077 bp
  • G to A, chromosome 15 at 55,792,222 bp
  • G to A, chromosome 15 at 98,852,109 bp
  • G to T, chromosome 17 at 37,446,082 bp
  • A to G, chromosome 18 at 37,520,135 bp
  • A to G, chromosome 18 at 60,692,021 bp
  • A to G, chromosome 18 at 61,990,688 bp
  • G to A, chromosome 19 at 8,937,582 bp
  • A to C, chromosome 19 at 12,108,659 bp
  • A to T, chromosome 19 at 13,342,157 bp
  • A to T, chromosome 19 at 36,881,776 bp
  • C to T, chromosome X at 74,277,038 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5467 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043028-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.