Strain Name:
C57BL/6J-MtgxR5484Btlr/Mmmh
Stock Number:
043045-MU
Citation ID:
RRID:MMRRC_043045-MU
Other Names:
R5484 (G1), C57BL/6J-MtgxR5484Btlr
Major Collection:

Gene Information

Tgfb1
Name: transforming growth factor, beta 1
Synonyms: TGF-beta 1, Tgfb, Tgfb-1, TGF-beta1, TGFbeta1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 21803
Homologene: 540
Chd7
Name: chromodomain helicase DNA binding protein 7
Synonyms: WBE1, Flo, GENA 60, GENA 47, Whi, Mt, Gena 52, Edy, Dz, A730019I05Rik, Todo, Obt, Cyn, Cycn, Lda
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 320790
Homologene: 19067
Sh3gl2
Name: SH3-domain GRB2-like 2
Synonyms: endophilin I, Sh3d2a, B930049H17Rik, 9530001L19Rik, endophilin A1, EEN-B1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 20404
Homologene: 20652
Mga
Name: MAX gene associated
Synonyms: Mga, Mad5, C130042M01Rik, D030062C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 29808
Homologene: 49351
Fam49b
Name: family with sequence similarity 49, member B
Synonyms: 0910001A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223601
VEGA: 15
Homologene: 9599
Zfp341
Name: zinc finger protein 341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228807
Homologene: 13127
Tcf7l2
Name: transcription factor 7 like 2, T cell specific, HMG box
Synonyms: Tcf4, Tcf-4, mTcf-4B, mTcf-4E, TCF4B, TCF4E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 21416
Homologene: 7564
Tpr
Name: translocated promoter region, nuclear basket protein
Synonyms: 2610029M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 108989
Homologene: 37753
Cry1
Name: cryptochrome 1 (photolyase-like)
Synonyms: Phll1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 12952
VEGA: 10
HGNC: HGNC:2384
Homologene: 7042
Dop1a
Name: DOP1 leucine zipper like protein A
Synonyms: B130005I07Rik, Dopey1, D9Ertd809e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 320615
Homologene: 26645
Setdb1
Name: SET domain, bifurcated 1
Synonyms: ESET, KMT1E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 84505
Homologene: 32157
Dmxl1
Name: Dmx-like 1
Synonyms: C630007L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240283
HGNC: HGNC:2937
Homologene: 21136
Safb2
Name: scaffold attachment factor B2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224902
Homologene: 35210
Dsp
Name: desmoplakin
Synonyms: 5730453H04Rik, DP, 2300002E22Rik, rul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Plxnb2
Name: plexin B2
Synonyms: 1110007H23Rik, Debt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 140570
HGNC: HGNC:9104
Homologene: 66630
Pms2
Name: PMS1 homolog2, mismatch repair system component
Synonyms: mismatch repair, DNA mismatch repair
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18861
HGNC: HGNC:9122
Homologene: 133560
Camkv
Name: CaM kinase-like vesicle-associated
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235604
Homologene: 56983
Kank4
Name: KN motif and ankyrin repeat domains 4
Synonyms: Ankrd38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242553
Homologene: 18244
Strip2
Name: striatin interacting protein 2
Synonyms: D330017J20Rik, Fam40b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 320609
Homologene: 66198
Farsb
Name: phenylalanyl-tRNA synthetase, beta subunit
Synonyms: Farslb, Frsb, PheRS alpha, Farsl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 23874
Homologene: 4160
Zfp655
Name: zinc finger protein 655
Synonyms: 2700038I16Rik, 9030409O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 72611
Homologene: 12473
Ccdc171
Name: coiled-coil domain containing 171
Synonyms: 4930418J05Rik, A330015D16Rik, 4930473A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 320226
Homologene: 27942
Atp4a
Name: ATPase, H+/K+ exchanging, gastric, alpha polypeptide
Synonyms: H+K+-transporting alpha 1, H+/K+-ATPase alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11944
HGNC: HGNC:819
Homologene: 68081
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 665700
Homologene: 90772
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545370
Homologene: 23741
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Celsr1
Name: cadherin, EGF LAG seven-pass G-type receptor 1
Synonyms: Scy, crash, Adgrc1, Crsh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12614
VEGA: 15
HGNC: HGNC:1850
Homologene: 7665
Rtp1
Name: receptor transporter protein 1
Synonyms: LOC239766, LOC385871
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 239766
VEGA: 16
Homologene: 17806
Plekhs1
Name: pleckstrin homology domain containing, family S member 1
Synonyms: 9930023K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226245
VEGA: 19
Homologene: 11770
Mroh2b
Name: maestro heat-like repeat family member 2B
Synonyms: 4930455B06Rik, Heatr7b2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223825
VEGA: 15
Homologene: 128807
Slc35b1
Name: solute carrier family 35, member B1
Synonyms: Ugalt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 110172
Homologene: 4252
Mroh2a
Name: maestro heat-like repeat family member 2A
Synonyms: ENSMUSG00000044873, Heatr7b1, OTTMUSG00000020804
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 100040766
Homologene: 85300
Nat8f2
Name: N-acetyltransferase 8 (GCN5-related) family member 2
Synonyms: Cml2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 93673
Abca6
Name: ATP-binding cassette, sub-family A (ABC1), member 6
Synonyms: 6330565N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76184
HGNC: HGNC:36
Homologene: 71264
Corin
Name: corin, serine peptidase
Synonyms: Lrp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 53419
Homologene: 4804
Myh4
Name: myosin, heavy polypeptide 4, skeletal muscle
Synonyms: MYH-2B, Minmus, Minimsc, Myhsf, MM, MyHC-IIb, MHC2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17884
HGNC: HGNC:7574
Homologene: 123880
Cmklr1
Name: chemokine-like receptor 1
Synonyms: ChemR23, Gpcr27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14747
HGNC: HGNC:2121
Homologene: 129967
Gm10782
Name: predicted gene 10782
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 100038494
VEGA: 13
Loxl1
Name: lysyl oxidase-like 1
Synonyms: LOXL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 16949
VEGA: 9
HGNC: HGNC:6665
Homologene: 4074
Sdk1
Name: sidekick cell adhesion molecule 1
Synonyms: 6720466O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330222
Homologene: 27395
Cttnbp2
Name: cortactin binding protein 2
Synonyms: ORF4, 3010022N24Rik, Cortbp2, 9130022E09Rik, 4732477G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 30785
Homologene: 14125
Zfp788
Name: zinc finger protein 788
Synonyms: 2810426N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67607
Homologene: 137363
Plin4
Name: perilipin 4
Synonyms: S3-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 57435
Homologene: 69311
Wfdc8
Name: WAP four-disulfide core domain 8
Synonyms: LOC277343
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 277343
Homologene: 33799
Fam129a
Name: family with sequence similarity 129, member A
Synonyms: Niban
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 63913
Homologene: 62170
Gopc
Name: golgi associated PDZ and coiled-coil motif containing
Synonyms: 2210402P09Rik, GOPC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 94221
VEGA: 10
Homologene: 10695
Marveld1
Name: MARVEL (membrane-associating) domain containing 1
Synonyms: Mrvldc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 277010
Homologene: 12881
Pebp4
Name: phosphatidylethanolamine binding protein 4
Synonyms: 1700081D17Rik, 1700051A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 73523
VEGA: 14
Homologene: 51650
4921509C19Rik
Name: RIKEN cDNA 4921509C19 gene
Synonyms: LOC381389
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 381393
Homologene: 72396
Polrmt
Name: polymerase (RNA) mitochondrial (DNA directed)
Synonyms: 1110018N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216151
HGNC: HGNC:9200
Homologene: 37996
Olfr1423
Name: olfactory receptor 1423
Synonyms: GA_x6K02T2RE5P-2393361-2392429, MOR239-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258675
Homologene: 128078
Tbx4
Name: T-box 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 21387
Homologene: 7968
Plekhg3
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 3
Synonyms: MGC40768
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 263406
VEGA: 12
Homologene: 77478
Ttc26
Name: tetratricopeptide repeat domain 26
Synonyms: hpy, hop, hydrocephalic-polydactyl, 9430097H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 264134
Homologene: 11786
Btnl10
Name: butyrophilin-like 10
Synonyms: Butr1, BUTR-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 192194
Homologene: 138184
Zfp874b
Name: zinc finger protein 874b
Synonyms: 9630025I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 408067
Homologene: 135597
Tmem132b
Name: transmembrane protein 132B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 208151
Homologene: 28135
Dnajb12
Name: DnaJ heat shock protein family (Hsp40) member B12
Synonyms: mDj10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 56709
Homologene: 9749
Catsperb
Name: cation channel sperm associated auxiliary subunit beta
Synonyms: 4932415G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 271036
VEGA: 12
Homologene: 81904
Irf3
Name: interferon regulatory factor 3
Synonyms: IRF-3, C920001K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 54131
HGNC: HGNC:6118
Homologene: 1208
Ifi209
Name: interferon activated gene 209
Synonyms: Pyhin-1, Pyhin1, Ifix
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 236312
HGNC: HGNC:5395
Homologene: 115929
Alx1
Name: ALX homeobox 1
Synonyms: Cart1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216285
HGNC: HGNC:1494
Homologene: 5075
Vmn2r44
Name: vomeronasal 2, receptor 44
Synonyms: EG434113
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434113
Homologene: 113703
Tmem176b
Name: transmembrane protein 176B
Synonyms: 1810009M01Rik, Clast1, Lr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 65963
Homologene: 8521
Pcdha9
Name: protocadherin alpha 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 192161
HGNC: HGNC:8664
Homologene: 130700
Gm10220
Name: predicted gene 10220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 434689
Homologene: 69402
Iqcf1
Name: IQ motif containing F1
Synonyms: 1700055J15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74267
Homologene: 45119
Pitx1
Name: paired-like homeodomain transcription factor 1
Synonyms: P-OTX, Bft, Potx, Ptx1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18740
HGNC: HGNC:9004
Homologene: 20584
Slc13a2os
Name: solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2, opposite strand
Synonyms: Gm11194
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 790911
Ascl4
Name: achaete-scute family bHLH transcription factor 4
Synonyms: 1700054F16Rik, bHLHa44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 67341
Homologene: 19806
Gm23230
Name: predicted gene, 23230
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
Tmem258
Name: transmembrane protein 258
Synonyms: 1810006K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 69038
HGNC: HGNC:1164
Homologene: 40931
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 78,476,196 bp
  • A to G, chromosome 1 at 88,258,664 bp
  • T to C, chromosome 1 at 150,426,888 bp
  • T to C, chromosome 1 at 150,675,540 bp
  • A to G, chromosome 1 at 151,718,086 bp
  • T to A, chromosome 1 at 173,641,074 bp
  • C to T, chromosome 2 at 31,393,054 bp
  • T to G, chromosome 2 at 119,916,626 bp
  • T to C, chromosome 2 at 151,471,931 bp
  • T to C, chromosome 2 at 154,625,001 bp
  • T to C, chromosome 2 at 164,597,729 bp
  • A to T, chromosome 3 at 95,337,258 bp
  • G to C, chromosome 4 at 8,828,258 bp
  • A to G, chromosome 4 at 83,693,962 bp
  • T to C, chromosome 4 at 85,398,923 bp
  • T to C, chromosome 4 at 98,774,785 bp
  • A to T, chromosome 4 at 114,845,051 bp
  • T to A, chromosome 5 at 26,117,932 bp
  • T to C, chromosome 5 at 72,358,484 bp
  • C to G, chromosome 5 at 113,614,929 bp
  • T to C, chromosome 5 at 125,787,733 bp
  • C to A, chromosome 5 at 142,100,186 bp
  • T to C, chromosome 5 at 143,928,125 bp
  • T to C, chromosome 5 at 145,243,635 bp
  • T to A, chromosome 6 at 18,427,690 bp
  • C to A, chromosome 6 at 29,917,155 bp
  • T to G, chromosome 6 at 38,389,122 bp
  • T to A, chromosome 6 at 48,834,533 bp
  • G to T, chromosome 6 at 73,092,116 bp
  • C to A, chromosome 6 at 85,868,012 bp
  • T to C, chromosome 7 at 8,380,124 bp
  • A to C, chromosome 7 at 25,688,149 bp
  • G to A, chromosome 7 at 30,720,672 bp
  • T to C, chromosome 7 at 41,649,853 bp
  • A to T, chromosome 7 at 44,999,958 bp
  • A to G, chromosome 9 at 58,290,782 bp
  • C to G, chromosome 9 at 86,545,288 bp
  • A to T, chromosome 9 at 106,501,908 bp
  • A to T, chromosome 9 at 107,946,146 bp
  • A to G, chromosome 10 at 52,358,846 bp
  • GC to G, chromosome 10 at 59,892,752 bp
  • A to G, chromosome 10 at 79,742,054 bp
  • T to C, chromosome 10 at 85,146,724 bp
  • T to C, chromosome 10 at 85,928,537 bp
  • T to A, chromosome 10 at 103,025,316 bp
  • G to A, chromosome 11 at 58,923,825 bp
  • A to G, chromosome 11 at 67,251,818 bp
  • G to A, chromosome 11 at 78,404,822 bp
  • A to G, chromosome 11 at 85,914,404 bp
  • T to C, chromosome 11 at 95,387,805 bp
  • A to T, chromosome 11 at 110,184,073 bp
  • G to A, chromosome 12 at 76,578,400 bp
  • T to C, chromosome 12 at 101,575,916 bp
  • A to G, chromosome 13 at 38,184,038 bp
  • A to G, chromosome 13 at 55,826,353 bp
  • G to T, chromosome 13 at 56,363,174 bp
  • C to T, chromosome 13 at 67,481,254 bp
  • A to T, chromosome 14 at 69,963,542 bp
  • A to G, chromosome 15 at 4,908,981 bp
  • T to A, chromosome 15 at 63,943,207 bp
  • T to C, chromosome 15 at 85,931,282 bp
  • T to C, chromosome 15 at 89,164,209 bp
  • A to G, chromosome 16 at 23,429,275 bp
  • T to C, chromosome 17 at 56,104,932 bp
  • T to C, chromosome 17 at 56,575,346 bp
  • T to A, chromosome 18 at 36,998,103 bp
  • T to A, chromosome 18 at 49,889,464 bp
  • A to G, chromosome 19 at 10,207,325 bp
  • G to A, chromosome 19 at 12,035,828 bp
  • T to C, chromosome 19 at 42,147,833 bp
  • C to A, chromosome 19 at 55,919,508 bp
  • C to T, chromosome 19 at 56,479,828 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5484 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043045-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.