Strain Name:
C57BL/6J-MtgxR5793Btlr/Mmmh
Stock Number:
043208-MU
Citation ID:
RRID:MMRRC_043208-MU
Other Names:
R5793 (G1), C57BL/6J-MtgxR5793Btlr
Major Collection:

Strain Information

Myh9
Name: myosin, heavy polypeptide 9, non-muscle
Synonyms: D0Jmb2, E030044M24Rik, NMHC II-A, Myhn-1, Myhn1, myosin IIA, Fltn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17886
HGNC: HGNC:7579
Homologene: 129835
Ncam2
Name: neural cell adhesion molecule 2
Synonyms: RNCAM, R4B12 antigen, Ncam-2, Ocam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 17968
HGNC: HGNC:7657
Homologene: 3336
Nsd1
Name: nuclear receptor-binding SET-domain protein 1
Synonyms: KMT3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18193
VEGA: 13
Homologene: 32543
Fkbp9
Name: FK506 binding protein 9
Synonyms: FKBP60, FKBP63
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 27055
HGNC: HGNC:3725
Homologene: 31434
Axin1
Name: axin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12005
HGNC: HGNC:903
Homologene: 2614
Ckap5
Name: cytoskeleton associated protein 5
Synonyms: 3110043H24Rik, 4930432B04Rik, D730027C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 75786
Homologene: 8844
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 1810014J18Rik, AD013, A330063D19Rik, 9030205D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 109151
Homologene: 11844
Orc2
Name: origin recognition complex, subunit 2
Synonyms: Orc2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18393
HGNC: HGNC:8488
Homologene: 4512
Arfgef1
Name: ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
Synonyms: D730028O18Rik, ARFGEP1, P200, BIG1, D130059B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 211673
Homologene: 4687
Palb2
Name: partner and localizer of BRCA2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233826
Homologene: 11652
Slitrk5
Name: SLIT and NTRK-like family, member 5
Synonyms: 2610019D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 75409
VEGA: 14
Homologene: 9193
Gprc5c
Name: G protein-coupled receptor, family C, group 5, member C
Synonyms: 1110028I06Rik, 3200002M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70355
Homologene: 11099
Qser1
Name: glutamine and serine rich 1
Synonyms: 4732486I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99003
Homologene: 11710
Ift172
Name: intraflagellar transport 172
Synonyms: wim, 4930553F24Rik, avc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67661
Homologene: 15202
Cdh23
Name: cadherin 23 (otocadherin)
Synonyms: 4930542A03Rik, USH1D, mdfw, ahl, bob, nmf112, nmf181, nmf252, sals
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22295
Homologene: 11142
Wdr72
Name: WD repeat domain 72
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 546144
Homologene: 52326
Tek
Name: TEK receptor tyrosine kinase
Synonyms: Hyk, Tie2, Cd202b, tie-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21687
Homologene: 397
Zfp580
Name: zinc finger protein 580
Synonyms: 1500015O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68992
Homologene: 82467
Rpgrip1l
Name: Rpgrip1-like
Synonyms: Ftm, 1700047E16Rik, fantom, Nphp8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244585
Homologene: 18296
Cspg4b
Name: chondroitin sulfate proteoglycan 4B
Synonyms: BC067074
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 408066
Wdr87-ps
Name: WD repeat domain 87, pseudogene
Synonyms: 4932431P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 114675
Sdk2
Name: sidekick cell adhesion molecule 2
Synonyms: 5330435L01Rik, 4632412F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237979
Homologene: 10406
Tmem132e
Name: transmembrane protein 132E
Synonyms: LOC270893
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 270893
Homologene: 41524
Ppfia4
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
Synonyms: 1110008G13Rik, LOC100042382, Liprin-alpha4, Gm3812
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68507
HGNC: HGNC:9248
Homologene: 66200
Pard3b
Name: par-3 family cell polarity regulator beta
Synonyms: 2810455B10Rik, PAR3beta, PAR3L, PAR3B, 2010002N16Rik, Als2cr19, 1810008K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72823
Homologene: 35389
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75777
Homologene: 44907
Ogdhl
Name: oxoglutarate dehydrogenase-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239017
VEGA: 14
Homologene: 56801
Tbc1d9
Name: TBC1 domain family, member 9
Synonyms: C76116, 4933431N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71310
Homologene: 57079
Kcnma1
Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Synonyms: Slo, mSlo1, Slo1, MaxiK, BK channel alpha subunit, 5730414M22Rik, BKCa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16531
HGNC: HGNC:6284
Homologene: 1693
Vmn2r84
Name: vomeronasal 2, receptor 84
Synonyms: EG625068
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 625068
Homologene: 129606
Ly6g2
Name: lymphocyte antigen 6 complex, locus G2
Synonyms: BC025446
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223631
Slc22a30
Name: solute carrier family 22, member 30
Synonyms: C730048C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 319800
Homologene: 77136
Padi2
Name: peptidyl arginine deiminase, type II
Synonyms: PAD type II, Pdi, Pdi2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18600
Homologene: 7214
B4galnt3
Name: beta-1,4-N-acetyl-galactosaminyl transferase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330406
Homologene: 18328
Snap47
Name: synaptosomal-associated protein, 47
Synonyms: SNAP-47, 1110031B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67826
Homologene: 14206
Hsd11b1
Name: hydroxysteroid 11-beta dehydrogenase 1
Synonyms: 11beta-hydroxysteroid dehydrogenase type 1, 11beta-HSD-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 15483
HGNC: HGNC:5208
Homologene: 68471
Alox12
Name: arachidonate 12-lipoxygenase
Synonyms: P-12LO, Alox12p, 9930022G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11684
HGNC: HGNC:429
Homologene: 560
Arg1
Name: arginase, liver
Synonyms: PGIF, Arg-1, AI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11846
VEGA: 10
HGNC: HGNC:663
Homologene: 29
Tsga10
Name: testis specific 10
Synonyms: 4933432N21Rik, Mtsga10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 211484
Homologene: 23531
Gm16332
Name: predicted gene 16332
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100417200
Dzank1
Name: double zinc ribbon and ankyrin repeat domains 1
Synonyms: 2810039F03Rik, Ankrd64, 6330439K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241688
Homologene: 10037
Gtpbp6
Name: GTP binding protein 6 (putative)
Synonyms: pgpl, Pgbpll
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 107999
Homologene: 8157
Gm4781
Name: predicted gene 4781
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 213051
VEGA: 10
Arhgap8
Name: Rho GTPase activating protein 8
Synonyms: 3110043J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 73167
HGNC: HGNC:677
Homologene: 23645
Pigz
Name: phosphatidylinositol glycan anchor biosynthesis, class Z
Synonyms: F630022B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239827
Homologene: 130742
Or51a24
Name: olfactory receptor family 51 subfamily A member 24
Synonyms: GA_x6K02T2PBJ9-6819097-6818150, MOR13-5, Olfr645
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258247
Homologene: 66155
Trim68
Name: tripartite motif-containing 68
Synonyms: SS-56, F730114J12Rik, Rnf137
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101700
Homologene: 9991
Zfp772
Name: zinc finger protein 772
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232855
Homologene: 128539
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 10,209,528 bp
  • A to T, chromosome 1 at 37,835,459 bp
  • T to C, chromosome 1 at 58,497,388 bp
  • A to T, chromosome 1 at 61,767,973 bp
  • A to G, chromosome 1 at 134,312,106 bp
  • C to A, chromosome 1 at 139,924,013 bp
  • A to C, chromosome 1 at 193,242,184 bp
  • C to T, chromosome 2 at 91,619,835 bp
  • T to C, chromosome 2 at 104,762,860 bp
  • T to C, chromosome 2 at 144,506,224 bp
  • T to A, chromosome 4 at 94,820,096 bp
  • T to C, chromosome 4 at 140,933,190 bp
  • A to T, chromosome 5 at 31,276,948 bp
  • G to A, chromosome 5 at 110,107,228 bp
  • G to A, chromosome 6 at 56,873,513 bp
  • A to G, chromosome 6 at 120,208,904 bp
  • A to T, chromosome 7 at 5,052,892 bp
  • G to A, chromosome 7 at 7,204,284 bp
  • A to G, chromosome 7 at 29,531,308 bp
  • A to T, chromosome 7 at 102,684,353 bp
  • T to C, chromosome 7 at 104,085,030 bp
  • T to C, chromosome 7 at 122,127,637 bp
  • A to T, chromosome 8 at 83,271,440 bp
  • A to G, chromosome 8 at 91,001,756 bp
  • A to G, chromosome 8 at 91,260,772 bp
  • C to T, chromosome 9 at 74,210,343 bp
  • C to T, chromosome 10 at 24,920,642 bp
  • T to A, chromosome 10 at 60,306,128 bp
  • T to A, chromosome 10 at 100,396,667 bp
  • C to T, chromosome 10 at 130,385,885 bp
  • C to T, chromosome 11 at 59,438,192 bp
  • C to A, chromosome 11 at 70,243,053 bp
  • T to A, chromosome 11 at 82,444,858 bp
  • T to C, chromosome 11 at 113,868,952 bp
  • G to T, chromosome 11 at 114,864,267 bp
  • T to C, chromosome 13 at 55,248,006 bp
  • G to T, chromosome 13 at 113,321,022 bp
  • C to T, chromosome 14 at 23,309,035 bp
  • T to A, chromosome 14 at 32,332,773 bp
  • T to A, chromosome 14 at 111,679,913 bp
  • G to T, chromosome 15 at 10,551,550 bp
  • T to C, chromosome 15 at 75,221,644 bp
  • T to C, chromosome 15 at 77,768,877 bp
  • T to A, chromosome 15 at 84,772,022 bp
  • T to C, chromosome 16 at 31,945,467 bp
  • G to A, chromosome 16 at 81,576,103 bp
  • T to C, chromosome 17 at 26,143,308 bp
  • T to A, chromosome 19 at 8,336,819 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5793 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043208-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.