Strain Name:
C57BL/6J-MtgxR5804Btlr/Mmmh
Stock Number:
043211-MU
Citation ID:
RRID:MMRRC_043211-MU
Other Names:
R5804 (G1), C57BL/6J-MtgxR5804Btlr
Major Collection:

Gene Information

Utrn
Name: utrophin
Synonyms: G-utrophin, DRP, Dmdl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22288
VEGA: 10
Homologene: 21398
Hmgcr
Name: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Synonyms: 3-hydroxy-3-methylglutaryl-CoA reductase, HMG-CoAR, Red
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 15357
HGNC: HGNC:5006
Homologene: 30994
Fmn2
Name: formin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 54418
Homologene: 137334
Mtcl1
Name: microtubule crosslinking factor 1
Synonyms: t8219b25, 1110012J17Rik, Soga2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 68617
Homologene: 41017
Psen1
Name: presenilin 1
Synonyms: Ad3h, PS1, PS-1, presenilin-1, S182
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 19164
VEGA: 12
HGNC: HGNC:9508
Homologene: 7186
Robo1
Name: roundabout guidance receptor 1
Synonyms: DUTT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 19876
Homologene: 2206
Ctsl
Name: cathepsin L
Synonyms: MEP, Cat L, 1190035F06Rik, major excreted protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13039
VEGA: 13
HGNC: HGNC:2538
Homologene: 76699
Npat
Name: nuclear protein in the AT region
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244879
HGNC: HGNC:7896
Homologene: 1888
Eif2b3
Name: eukaryotic translation initiation factor 2B, subunit 3
Synonyms: 1190002P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 108067
HGNC: HGNC:3259
Homologene: 7005
Ube2cbp
Name: ubiquitin-conjugating enzyme E2C binding protein
Synonyms: 2610018I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 70348
Homologene: 18898
Dse
Name: dermatan sulfate epimerase
Synonyms: B130024B19Rik, DS-epi1, Sart2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 212898
VEGA: 10
Homologene: 8354
Heatr5b
Name: HEAT repeat containing 5B
Synonyms: D330050P16Rik, A230048G03Rik, 2010013B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 320473
VEGA: 17
Homologene: 25536
Lrrc8c
Name: leucine rich repeat containing 8 family, member C
Synonyms: E430036I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100604
Homologene: 12997
Jag1
Name: jagged 1
Synonyms: Ozz, Serrate-1, Gsfabe2, Htu, ABE2, Headturner
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16449
HGNC: HGNC:6188
Homologene: 180
Slc16a4
Name: solute carrier family 16 (monocarboxylic acid transporters), member 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229699
Homologene: 74529
Cfap74
Name: cilia and flagella associated protein 74
Synonyms: 2010015L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 544678
Homologene: 129584
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545370
Homologene: 23741
Ctu2
Name: cytosolic thiouridylase subunit 2
Synonyms: 2310061F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 66965
Homologene: 79815
Hivep2
Name: human immunodeficiency virus type I enhancer binding protein 2
Synonyms: MIBP1, Gm20114, Shn-2, Schnurri-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 15273
HGNC: HGNC:4921
Homologene: 4900
Slc4a8
Name: solute carrier family 4 (anion exchanger), member 8
Synonyms: sodium bicarbonate cotransporter isoform 3 kNBC-3, KNBC-3, NDCBE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 59033
Homologene: 68419
Flt1
Name: FMS-like tyrosine kinase 1
Synonyms: vascular endothelial growth factor receptor-1, VEGFR-1, Flt-1, VEGFR1, sFlt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14254
HGNC: HGNC:3763
Homologene: 134179
Hfm1
Name: HFM1, ATP-dependent DNA helicase homolog
Synonyms: A330009G12Rik, LOC381663, Sec63d1, Mer3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330149
Homologene: 87103
Grm3
Name: glutamate receptor, metabotropic 3
Synonyms: Gprc1c, 0710001G23Rik, mGlu3, mGluR3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 108069
HGNC: HGNC:4595
Homologene: 651
Poteg
Name: POTE ankyrin domain family, member G
Synonyms: 4930456F22Rik, 4921537P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 70952
Homologene: 134158
Abcb9
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 9
Synonyms: TAPL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56325
HGNC: HGNC:50
Homologene: 10491
Gatm
Name: glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Synonyms: 1810003P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67092
HGNC: HGNC:4175
Homologene: 1136
Nin
Name: ninein
Synonyms: 3110068G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 18080
Homologene: 40632
Gpaa1
Name: GPI anchor attachment protein 1
Synonyms: mGAA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 14731
HGNC: HGNC:4446
Homologene: 37852
Stmn4
Name: stathmin-like 4
Synonyms: RB3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 56471
Homologene: 10496
Pfpl
Name: pore forming protein-like
Synonyms: Epcs5, Epcs50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 56093
VEGA: 19
Homologene: 130704
Olfr1006
Name: olfactory receptor 1006
Synonyms: MOR213-4, GA_x6K02T2Q125-47154544-47153606
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258563
Homologene: 17295
Ugt2b36
Name: UDP glucuronosyltransferase 2 family, polypeptide B36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231396
Homologene: 128251
Rassf9
Name: Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
Synonyms: Pamci
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237504
Homologene: 3976
Tex26
Name: testis expressed 26
Synonyms: 4930588N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 75860
Homologene: 51841
Olfr640
Name: olfactory receptor 640
Synonyms: GA_x6K02T2PBJ9-6756759-6755815, MOR13-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258819
Homologene: 17404
Zbtb22
Name: zinc finger and BTB domain containing 22
Synonyms: 1110008J20Rik, Bing1, Zfp297
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 81630
Homologene: 3982
Igsf21
Name: immunoglobulin superfamily, member 21
Synonyms: LOC230868
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230868
Homologene: 13153
Klrc2
Name: killer cell lectin-like receptor subfamily C, member 2
Synonyms: NKG2C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16642
HGNC: HGNC:6375
Homologene: 130643
Ubash3a
Name: ubiquitin associated and SH3 domain containing, A
Synonyms: Sts-2, 5830413C03Rik, TULA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 328795
Homologene: 56833
Olfr1262
Name: olfactory receptor 1262
Synonyms: MOR234-1, GA_x6K02T2Q125-51434523-51435437
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258976
Homologene: 74064
Ager
Name: advanced glycosylation end product-specific receptor
Synonyms: RAGE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 11596
HGNC: HGNC:320
Homologene: 883
Gm20388
Name: predicted gene 20388
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
Zfp41
Name: zinc finger protein 41
Synonyms: CTfin92, Zfp-41
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 22701
Homologene: 65280
Cfap97d1
Name: CFAP97 domain containing 1
Synonyms: 1700006E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75437
Homologene: 19137
Olfr283
Name: olfactory receptor 283
Synonyms: MOR160-1, GA_x6K02T2NBG7-5351896-5352825
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 259038
Homologene: 64944
Abat
Name: 4-aminobutyrate aminotransferase
Synonyms: 9630038C02Rik, GABA-T
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 268860
HGNC: HGNC:23
Homologene: 542
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 150,674,347 bp
  • T to C, chromosome 1 at 174,537,178 bp
  • T to A, chromosome 2 at 76,916,819 bp
  • T to A, chromosome 2 at 85,674,338 bp
  • T to C, chromosome 2 at 90,002,988 bp
  • T to A, chromosome 2 at 122,602,602 bp
  • T to C, chromosome 2 at 137,088,204 bp
  • A to T, chromosome 3 at 107,298,964 bp
  • G to T, chromosome 4 at 117,086,714 bp
  • A to T, chromosome 4 at 140,028,074 bp
  • A to G, chromosome 4 at 155,447,576 bp
  • A to G, chromosome 5 at 9,570,155 bp
  • G to C, chromosome 5 at 87,081,004 bp
  • A to T, chromosome 5 at 105,579,557 bp
  • A to G, chromosome 5 at 106,878,589 bp
  • A to G, chromosome 5 at 124,080,055 bp
  • A to T, chromosome 5 at 147,580,437 bp
  • A to G, chromosome 5 at 149,463,147 bp
  • A to T, chromosome 6 at 129,660,473 bp
  • T to C, chromosome 7 at 104,022,232 bp
  • A to G, chromosome 8 at 27,456,798 bp
  • T to C, chromosome 8 at 122,481,226 bp
  • T to A, chromosome 8 at 123,228,840 bp
  • C to T, chromosome 9 at 53,566,745 bp
  • T to C, chromosome 9 at 86,425,348 bp
  • T to A, chromosome 10 at 12,421,625 bp
  • A to C, chromosome 10 at 14,133,775 bp
  • T to A, chromosome 10 at 34,153,379 bp
  • A to T, chromosome 10 at 102,545,044 bp
  • A to G, chromosome 11 at 101,990,814 bp
  • C to T, chromosome 12 at 70,045,601 bp
  • T to C, chromosome 12 at 83,731,700 bp
  • A to T, chromosome 13 at 64,366,488 bp
  • G to A, chromosome 13 at 96,666,187 bp
  • G to A, chromosome 14 at 66,356,299 bp
  • C to T, chromosome 15 at 75,618,708 bp
  • T to C, chromosome 15 at 76,332,626 bp
  • T to A, chromosome 15 at 98,378,334 bp
  • A to G, chromosome 15 at 100,791,625 bp
  • A to T, chromosome 16 at 8,578,236 bp
  • T to C, chromosome 16 at 73,043,189 bp
  • G to A, chromosome 17 at 31,208,232 bp
  • TGGACCCGGGAC to TGGACCCGGGACCCGGGAC, chromosome 17 at 33,918,619 bp
  • A to G, chromosome 17 at 34,598,183 bp
  • A to C, chromosome 17 at 66,343,137 bp
  • G to A, chromosome 17 at 78,831,522 bp
  • A to T, chromosome 19 at 12,429,663 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5804 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043211-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.