Strain Name:
C57BL/6J-MtgxR5588Btlr
Stock Number:
043268-MU
Citation ID:
RRID:MMRRC_043268-MU
Other Names:
R5588 (G1)
Major Collection:

Gene Information

Rtel1
Name: regulator of telomere elongation helicase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269400
Homologene: 13168
Nup155
Name: nucleoporin 155
Synonyms: D930027M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 170762
VEGA: 15
HGNC: HGNC:8063
Homologene: 43155
Pdzd2
Name: PDZ domain containing 2
Synonyms: Pdzk3, 4930537L06Rik, A930022H17Rik, LOC223364, Gm21706
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68070
Homologene: 23393
Slc37a1
Name: solute carrier family 37 (glycerol-3-phosphate transporter), member 1
Synonyms: G3PP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224674
VEGA: 17
Homologene: 70486
Ticrr
Name: TOPBP1-interacting checkpoint and replication regulator
Synonyms: 5730590G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 77011
Homologene: 67120
Pcnt
Name: pericentrin (kendrin)
Synonyms: m275Asp, m239Asp, Pcnt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18541
VEGA: 10
Kif5b
Name: kinesin family member 5B
Synonyms: Khc, kinesin heavy chain
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16573
HGNC: HGNC:6324
Homologene: 55829
Ncapg2
Name: non-SMC condensin II complex, subunit G2
Synonyms: 5830426I05Rik, mCAP-G2, Luzp5, Mtb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 76044
VEGA: 12
Homologene: 9820
Cobl
Name: cordon-bleu WH2 repeat
Synonyms: C530045F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12808
Homologene: 9058
Fbxo38
Name: F-box protein 38
Synonyms: 6030410I24Rik, SP329
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 107035
VEGA: 18
Homologene: 34526
Smc4
Name: structural maintenance of chromosomes 4
Synonyms: 2500002A22Rik, Smc4l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70099
Homologene: 4015
Gapvd1
Name: GTPase activating protein and VPS9 domains 1
Synonyms: 2010005B09Rik, 4432404J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66691
Homologene: 32637
Srprb
Name: signal recognition particle receptor, B subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20818
Homologene: 6332
Eif4a3
Name: eukaryotic translation initiation factor 4A3
Synonyms: Ddx48, 2400003O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192170
Homologene: 5602
Afg3l2
Name: AFG3-like AAA ATPase 2
Synonyms: par, Emv66, 2310036I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 69597
VEGA: 18
HGNC: HGNC:315
Homologene: 4947
Rfx2
Name: regulatory factor X, 2 (influences HLA class II expression)
Synonyms: 5430432H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 19725
VEGA: 17
HGNC: HGNC:9983
Homologene: 30980
Lmo7
Name: LIM domain only 7
Synonyms: FBXO20, LOC380928
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
Tnc
Name: tenascin C
Synonyms: tenascin-C, TN, hexabrachion, TN-C, cytotactin, Hxb, C130033P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21923
HGNC: HGNC:5318
Homologene: 55636
Per1
Name: period circadian clock 1
Synonyms: mPer1, m-rigui, Hftm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18626
HGNC: HGNC:8845
Homologene: 1966
Eea1
Name: early endosome antigen 1
Synonyms: A430109M19Rik, ZFYVE2, B230358H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216238
VEGA: 10
HGNC: HGNC:3185
Homologene: 37822
Ccdc85c
Name: coiled-coil domain containing 85C
Synonyms: hhy, Gm9010
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 668158
VEGA: 12
Homologene: 82238
Fhdc1
Name: FH2 domain containing 1
Synonyms: 6330505N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229474
Homologene: 18920
Fgd3
Name: FYVE, RhoGEF and PH domain containing 3
Synonyms: 5830461L01Rik, ZFYVE5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 30938
Homologene: 22925
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh4, C130041O22Rik, Zfh-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80892
Homologene: 23477
Aldh1a2
Name: aldehyde dehydrogenase family 1, subfamily A2
Synonyms: Raldh2, retinaldehyde dehydrogenase, Aldh1a7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19378
Homologene: 68368
Mlph
Name: melanophilin
Synonyms: D1Wsu84e, Slac-2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 171531
Homologene: 11465
Tex15
Name: testis expressed gene 15
Synonyms: 2210014E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 104271
Homologene: 12837
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26875
Homologene: 69111
Fat2
Name: FAT atypical cadherin 2
Synonyms: Fath2, EMI2, mKIAA0811, LOC245827
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Cyp2c66
Name: cytochrome P450, family 2, subfamily c, polypeptide 66
Synonyms: 2010301M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 69888
HGNC: HGNC:2623
Homologene: 133566
Gsap
Name: gamma-secretase activating protein
Synonyms: A530088I07Rik, Pion
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 212167
Homologene: 45504
Plb1
Name: phospholipase B1
Synonyms: 4930433E17Rik, 4632413E21Rik, 4930539A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 665270
Homologene: 82108
Kcnab1
Name: potassium voltage-gated channel, shaker-related subfamily, beta member 1
Synonyms: Akr8a8, Kvbeta1.1, mKv(beta)1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 16497
HGNC: HGNC:6228
Homologene: 56491
Tdrd7
Name: tudor domain containing 7
Synonyms: 5730495N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100121
Homologene: 8618
Phf8-ps
Name: PHD finger protein 8, pseudogene
Synonyms: 4921501E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74042
VEGA: 17
Homologene: 66275
4930407I10Rik
Name: RIKEN cDNA 4930407I10 gene
Synonyms: LOC328573
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 328573
VEGA: 15
Homologene: 130065
Vmn2r5
Name: vomeronasal 2, receptor 5
Synonyms: EG667060
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 667060
Ubqlnl
Name: ubiquilin-like
Synonyms: LOC244179, 4922504M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244179
Homologene: 17034
Vmn1r194
Name: vomeronasal 1 receptor 194
Synonyms: Gm11294
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 626299
Homologene: 110880
Elfn2
Name: leucine rich repeat and fibronectin type III, extracellular 2
Synonyms: Lrrc62
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 207393
VEGA: 15
Homologene: 18835
Bdh1
Name: 3-hydroxybutyrate dehydrogenase, type 1
Synonyms: 2310032J20Rik, Bdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 71911
HGNC: HGNC:1027
Homologene: 20860
Lilr4b
Name: leukocyte immunoglobulin-like receptor, subfamily B, member 4B
Synonyms: gp49, Gp49a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14727
HGNC: HGNC:6608
Homologene: 86756
Tpte
Name: transmembrane phosphatase with tensin homology
Synonyms: Pten2, Vsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234129
Homologene: 50411
Sec14l3
Name: SEC14-like lipid binding 3
Synonyms: 1110069O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380683
Homologene: 24848
Atp8a1
Name: ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
Synonyms: B230107D19Rik, Atp3a2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11980
Homologene: 48402
Dhx34
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 34
Synonyms: 1200013B07Rik, 1810012L18Rik, Ddx34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71723
Homologene: 69171
Skint8
Name: selection and upkeep of intraepithelial T cells 8
Synonyms: OTTMUSG00000009475
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 639774
Homologene: 106613
Parva
Name: parvin, alpha
Synonyms: 2010012A22Rik, actopaxin, 5430400F08Rik, CH-ILKBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57342
Homologene: 10077
Eif2b4
Name: eukaryotic translation initiation factor 2B, subunit 4 delta
Synonyms: Eif2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13667
HGNC: HGNC:3260
Homologene: 5976
Olfr1259
Name: olfactory receptor 1259
Synonyms: GA_x6K02T2Q125-51376062-51375133, MOR232-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258338
Homologene: 128115
Olfr802
Name: olfactory receptor 802
Synonyms: GA_x6K02T2PULF-11361362-11360424, MOR111-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258934
HGNC: HGNC:8355
Homologene: 105151
Olfr1240
Name: olfactory receptor 1240
Synonyms: MOR231-8, GA_x6K02T2Q125-50883183-50882239
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258804
Homologene: 121591
A430078G23Rik
Name: RIKEN cDNA A430078G23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Slc19a3
Name: solute carrier family 19, member 3
Synonyms: ThTr2, A230084E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 80721
Homologene: 23530
Gask1a
Name: golgi associated kinase 1A
Synonyms: C730027P07Rik, Fam198a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245050
VEGA: 9
Homologene: 18620
Olfml2a
Name: olfactomedin-like 2A
Synonyms: 4932431K08Rik, photomedin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241327
Homologene: 35248
Nedd9
Name: neural precursor cell expressed, developmentally down-regulated gene 9
Synonyms: Cas-L, HEF1, CasL, E230025G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18003
VEGA: 13
HGNC: HGNC:7733
Homologene: 4669
Vmn2r130
Name: vomeronasal 2, receptor 130
Synonyms: Vmn2r-ps130
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100042225
Gm5141
Name: predicted gene 5141
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 380850
Homologene: 136271
Ppp1r14a
Name: protein phosphatase 1, regulatory inhibitor subunit 14A
Synonyms: 1110001M11Rik, Cpi17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68458
Homologene: 12267
Gm14418
Name: predicted gene 14418
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668066
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 83,023,055 bp
  • T to C, chromosome 1 at 90,931,599 bp
  • T to A, chromosome 2 at 34,709,154 bp
  • T to C, chromosome 2 at 38,960,035 bp
  • T to C, chromosome 2 at 89,439,416 bp
  • T to A, chromosome 2 at 89,943,792 bp
  • A to T, chromosome 2 at 177,387,272 bp
  • T to C, chromosome 2 at 181,352,100 bp
  • T to G, chromosome 3 at 5,403,138 bp
  • T to C, chromosome 3 at 64,504,076 bp
  • A to C, chromosome 3 at 65,376,555 bp
  • A to G, chromosome 3 at 69,025,857 bp
  • A to G, chromosome 3 at 84,465,476 bp
  • T to A, chromosome 4 at 45,992,225 bp
  • T to G, chromosome 4 at 64,006,422 bp
  • A to T, chromosome 4 at 111,936,892 bp
  • T to A, chromosome 5 at 14,788,398 bp
  • A to C, chromosome 5 at 21,251,149 bp
  • A to T, chromosome 5 at 31,192,173 bp
  • G to A, chromosome 5 at 32,329,949 bp
  • A to G, chromosome 5 at 67,814,684 bp
  • T to C, chromosome 7 at 16,198,900 bp
  • C to T, chromosome 7 at 29,293,284 bp
  • C to T, chromosome 7 at 79,679,105 bp
  • T to A, chromosome 7 at 104,149,132 bp
  • C to A, chromosome 7 at 112,560,062 bp
  • T to A, chromosome 8 at 3,388,878 bp
  • T to A, chromosome 8 at 22,284,967 bp
  • T to C, chromosome 8 at 33,577,187 bp
  • G to A, chromosome 9 at 71,283,450 bp
  • G to T, chromosome 9 at 103,198,849 bp
  • C to T, chromosome 9 at 121,965,181 bp
  • G to A, chromosome 10 at 51,481,326 bp
  • T to C, chromosome 10 at 76,442,611 bp
  • T to C, chromosome 10 at 96,023,910 bp
  • T to G, chromosome 10 at 129,681,836 bp
  • T to C, chromosome 11 at 4,066,138 bp
  • A to T, chromosome 11 at 12,343,886 bp
  • T to A, chromosome 11 at 55,282,277 bp
  • G to A, chromosome 11 at 69,107,627 bp
  • A to C, chromosome 11 at 119,296,126 bp
  • T to C, chromosome 12 at 108,211,534 bp
  • T to C, chromosome 12 at 116,413,077 bp
  • T to C, chromosome 13 at 22,244,342 bp
  • A to T, chromosome 13 at 41,315,961 bp
  • A to T, chromosome 13 at 49,287,310 bp
  • A to T, chromosome 13 at 62,773,770 bp
  • T to C, chromosome 14 at 101,896,590 bp
  • G to A, chromosome 15 at 8,119,253 bp
  • A to C, chromosome 15 at 12,374,281 bp
  • T to C, chromosome 15 at 78,673,876 bp
  • C to A, chromosome 15 at 82,065,216 bp
  • T to C, chromosome 16 at 31,438,119 bp
  • A to T, chromosome 17 at 23,063,829 bp
  • T to A, chromosome 17 at 31,346,457 bp
  • G to A, chromosome 17 at 33,066,275 bp
  • A to T, chromosome 17 at 56,779,890 bp
  • T to G, chromosome 18 at 6,225,787 bp
  • A to G, chromosome 18 at 62,526,177 bp
  • A to T, chromosome 18 at 67,440,207 bp
  • A to G, chromosome 19 at 39,163,414 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5588 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043268-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.