Strain Name:
C57BL/6J-MtgxR5607Btlr
Stock Number:
043271-MU
Citation ID:
RRID:MMRRC_043271-MU
Other Names:
R5607 (G1)
Major Collection:

Gene Information

Ctnna1
Name: catenin (cadherin associated protein), alpha 1
Synonyms: alpha(E)-catenin, alpha E catenin, Catna1, 2010010M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 12385
VEGA: 18
HGNC: HGNC:2509
Homologene: 1433
Ppp1r13b
Name: protein phosphatase 1, regulatory subunit 13B
Synonyms: ASPP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 21981
VEGA: 12
Homologene: 9090
Smg7
Name: SMG7 nonsense mediated mRNA decay factor
Synonyms: 9430023P16Rik, Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226517
Homologene: 32235
Fmn2
Name: formin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 54418
Homologene: 137334
Exoc6
Name: exocyst complex component 6
Synonyms: msec15, 4833405E05Rik, Sec15, Sec15l1, hbd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107371
VEGA: 19
Homologene: 41305
Sf3a3
Name: splicing factor 3a, subunit 3
Synonyms: 4930512K19Rik, 60kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75062
Homologene: 4949
Nrf1
Name: nuclear respiratory factor 1
Synonyms: D6Ertd415e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18181
HGNC: HGNC:7996
Homologene: 3674
Rbbp6
Name: retinoblastoma binding protein 6, ubiquitin ligase
Synonyms: 4933422O15Rik, C030034J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19647
HGNC: HGNC:9889
Homologene: 136812
Myo9a
Name: myosin IXa
Synonyms: 4732465J09Rik, C130068I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270163
HGNC: HGNC:7608
Homologene: 21371
Mex3c
Name: mex3 RNA binding family member C
Synonyms: BM-013, A130001D14Rik, Rkhd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240396
Homologene: 9601
Adgrl1
Name: adhesion G protein-coupled receptor L1
Synonyms: Lec2, lectomedin-2, 2900070I05Rik, Lphn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 330814
Homologene: 8951
Rag1
Name: recombination activating 1
Synonyms: Rag-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19373
HGNC: HGNC:9831
Homologene: 387
Mmp14
Name: matrix metallopeptidase 14 (membrane-inserted)
Synonyms: Membrane type 1-MMP, MT1-MMP, sabe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 17387
HGNC: HGNC:7160
Homologene: 21040
Msh6
Name: mutS homolog 6
Synonyms: Msh6, GTBP, Gtmbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17688
VEGA: 17
HGNC: HGNC:7329
Homologene: 149
Fchsd1
Name: FCH and double SH3 domains 1
Synonyms: A030002D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 319262
Homologene: 14127
Cenpe
Name: centromere protein E
Synonyms: N-7 kinesin, CENP-E, 312kDa, Kif10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229841
HGNC: HGNC:1856
Homologene: 20429
Mcm6
Name: minichromosome maintenance complex component 6
Synonyms: Mcmd6, D1Wsu22e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17219
HGNC: HGNC:6949
Homologene: 4322
Ubr2
Name: ubiquitin protein ligase E3 component n-recognin 2
Synonyms: 9930021A08Rik, E130209G04Rik, ENSMUSG00000043296
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224826
VEGA: 17
Homologene: 26151
Tbc1d32
Name: TBC1 domain family, member 32
Synonyms: C6orf170, Bromi, D630037F22Rik, b2b2284Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 544696
VEGA: 10
Homologene: 51889
Zscan22
Name: zinc finger and SCAN domain containing 22
Synonyms: D530006B18Rik, Hkr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232878
HGNC: HGNC:4929
Homologene: 68122
Pkp2
Name: plakophilin 2
Synonyms: 1200012P04Rik, 1200008D14Rik, Pkp2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67451
HGNC: HGNC:9024
Homologene: 3364
Lig1
Name: ligase I, DNA, ATP-dependent
Synonyms: mLigI, LigI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16881
HGNC: HGNC:6598
Homologene: 197
Uggt2
Name: UDP-glucose glycoprotein glucosyltransferase 2
Synonyms: 3110001A05Rik, 1810064L21Rik, 3110027P15Rik, A230065J02Rik, Ugcgl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66435
Homologene: 56875
Otop1
Name: otopetrin 1
Synonyms: A530025J20Rik, tlt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21906
Homologene: 35244
Casp1
Name: caspase 1
Synonyms: ICE, Caspase-1, interleukin 1 beta-converting enzyme, Il1bc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12362
VEGA: 9
HGNC: HGNC:1499
Homologene: 133272
Cdh13
Name: cadherin 13
Synonyms: T-cadherin, Tcad, 4932416G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12554
HGNC: HGNC:1753
Homologene: 20335
Tubgcp6
Name: tubulin, gamma complex associated protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 328580
Homologene: 32477
Bmpr1b
Name: bone morphogenetic protein receptor, type 1B
Synonyms: Alk6, CFK-43a, Acvrlk6, BMPR-IB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12167
HGNC: HGNC:1077
Homologene: 20322
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Nxpe5
Name: neurexophilin and PC-esterase domain family, member 5
Synonyms: Fam55 related, BC055004
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381680
Homologene: 134143
Vmn2r25
Name: vomeronasal 2, receptor 25
Synonyms: EG545874
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 545874
Homologene: 135915
Dennd5a
Name: DENN/MADD domain containing 5A
Synonyms: ORF37, 1500012B19Rik, Rab6ip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19347
Homologene: 14584
Olfr591
Name: olfactory receptor 591
Synonyms: GA_x6K02T2PBJ9-5889409-5888465, MOR24-1P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258139
Homologene: 79429
Nepn
Name: nephrocan
Synonyms: 5730521E12Rik, Npn, periolin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66650
Homologene: 23549
Slco1b2
Name: solute carrier organic anion transporter family, member 1b2
Synonyms: mlst-1, Slc21a6, Slc21a10, Oatp1b2, 7330442B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 28253
Homologene: 75119
Olfr862
Name: olfactory receptor 862
Synonyms: GA_x6K02T2PVTD-13624132-13623212, MOR146-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258555
Homologene: 115540
Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Synonyms: Cav2.3, Cchra1, alpha1E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12290
HGNC: HGNC:1392
Homologene: 20185
Pop5
Name: processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
Synonyms: 1500019J17Rik, Rnasep3, 2700077E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 117109
Homologene: 41076
Smarcal1
Name: SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
Synonyms: Mharp, 6030401P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 54380
Homologene: 8558
Tex14
Name: testis expressed gene 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 83560
Homologene: 12838
Olfr1354
Name: olfactory receptor 1354
Synonyms: GA_x6K02T03FR9-4826-3919, GA_x6K02T2QGN0-2895081-2894349, MOR185-8, MOR139-7, MOR139-5, EG257869, Olfr233-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 259163
Homologene: 136441
Ttbk2
Name: tau tubulin kinase 2
Synonyms: TTK, B930008N24Rik, 2610507N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 140810
Homologene: 62795
Lrrc31
Name: leucine rich repeat containing 31
Synonyms: E230002P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 320352
Ankmy1
Name: ankyrin repeat and MYND domain containing 1
Synonyms: 4930483I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241158
Homologene: 9561
Qrfpr
Name: pyroglutamylated RFamide peptide receptor
Synonyms: AQ27, Gpr103
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229214
Homologene: 18865
Olfr617
Name: olfactory receptor 617
Synonyms: GA_x6K02T2PBJ9-6306819-6307775, MOR31-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258838
Homologene: 105208
Blvrb
Name: biliverdin reductase B (flavin reductase (NADPH))
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233016
HGNC: HGNC:1063
Homologene: 573
Ajap1
Name: adherens junction associated protein 1
Synonyms: LOC230959
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230959
Homologene: 10312
Preb
Name: prolactin regulatory element binding
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 50907
HGNC: HGNC:9356
Homologene: 40877
H2-Aa
Name: histocompatibility 2, class II antigen A, alpha
Synonyms: Aalpha, A alpha, Ia-1, Ia1, H-2Aa, I-Aalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14960
HGNC: HGNC:4942
Homologene: 123820
Cacng4
Name: calcium channel, voltage-dependent, gamma subunit 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 54377
HGNC: HGNC:1408
Homologene: 8674
Tspan1
Name: tetraspanin 1
Synonyms: 9030418M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66805
Homologene: 21170
Olfr536
Name: olfactory receptor 536
Synonyms: GA_x6K02T2PBJ9-42653501-42652578, MOR252-1, MOR252-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258513
Homologene: 51731
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 72,586,213 bp
  • A to G, chromosome 1 at 92,877,018 bp
  • T to C, chromosome 1 at 128,355,589 bp
  • A to G, chromosome 1 at 152,843,234 bp
  • T to A, chromosome 1 at 154,471,340 bp
  • G to A, chromosome 1 at 174,609,811 bp
  • G to A, chromosome 2 at 101,643,792 bp
  • A to G, chromosome 2 at 120,806,824 bp
  • C to A, chromosome 3 at 30,689,845 bp
  • A to G, chromosome 3 at 36,180,965 bp
  • C to A, chromosome 3 at 135,235,076 bp
  • C to A, chromosome 3 at 141,857,522 bp
  • A to G, chromosome 4 at 116,164,080 bp
  • A to T, chromosome 4 at 124,714,953 bp
  • T to A, chromosome 4 at 153,432,204 bp
  • G to T, chromosome 5 at 30,959,963 bp
  • G to A, chromosome 5 at 38,294,504 bp
  • G to A, chromosome 5 at 115,240,201 bp
  • A to G, chromosome 5 at 138,239,771 bp
  • C to T, chromosome 6 at 30,126,246 bp
  • T to C, chromosome 6 at 123,828,359 bp
  • A to G, chromosome 6 at 141,685,586 bp
  • G to A, chromosome 7 at 12,906,992 bp
  • C to A, chromosome 7 at 13,306,008 bp
  • C to T, chromosome 7 at 27,459,469 bp
  • T to C, chromosome 7 at 103,172,849 bp
  • G to A, chromosome 7 at 103,584,299 bp
  • C to A, chromosome 7 at 109,919,423 bp
  • T to A, chromosome 7 at 122,997,086 bp
  • A to C, chromosome 7 at 140,504,405 bp
  • G to T, chromosome 8 at 83,937,257 bp
  • A to T, chromosome 8 at 118,757,474 bp
  • T to C, chromosome 9 at 5,303,143 bp
  • T to A, chromosome 9 at 19,883,976 bp
  • T to C, chromosome 9 at 59,863,944 bp
  • A to T, chromosome 10 at 52,401,137 bp
  • A to T, chromosome 10 at 56,129,150 bp
  • A to G, chromosome 10 at 78,917,099 bp
  • T to G, chromosome 11 at 59,122,848 bp
  • A to G, chromosome 11 at 87,522,578 bp
  • A to T, chromosome 11 at 107,734,784 bp
  • T to C, chromosome 12 at 111,833,789 bp
  • TTGTTGTCTTTGTGTT to TTGTT, chromosome 14 at 47,734,097 bp
  • T to C, chromosome 14 at 54,439,412 bp
  • C to T, chromosome 14 at 119,089,199 bp
  • A to G, chromosome 15 at 89,111,150 bp
  • G to T, chromosome 16 at 16,260,375 bp
  • T to C, chromosome 17 at 34,283,842 bp
  • G to T, chromosome 17 at 46,934,200 bp
  • A to G, chromosome 17 at 87,986,901 bp
  • A to G, chromosome 18 at 35,249,742 bp
  • C to T, chromosome 18 at 37,959,873 bp
  • T to A, chromosome 18 at 73,589,943 bp
  • T to A, chromosome 19 at 37,578,529 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5607 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043271-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.