Strain Name:
C57BL/6J-MtgxR5632Btlr
Stock Number:
043283-MU
Citation ID:
RRID:MMRRC_043283-MU
Other Names:
R5632 (G1)
Major Collection:

Gene Information

Ncor1
Name: nuclear receptor co-repressor 1
Synonyms: N-CoR, Rxrip13, A230020K14Rik, 5730405M06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20185
HGNC: HGNC:7672
Homologene: 38166
H2-DMa
Name: histocompatibility 2, class II, locus DMa
Synonyms: H2-Ma, H-2Ma, H2-M alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14998
HGNC: HGNC:4934
Homologene: 4464
Slc12a5
Name: solute carrier family 12, member 5
Synonyms: KCC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 57138
Homologene: 10665
Jarid2
Name: jumonji, AT rich interactive domain 2
Synonyms: Jmj, jumonji
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 16468
HGNC: HGNC:6196
Homologene: 31279
Pex7
Name: peroxisomal biogenesis factor 7
Synonyms: peroxisome biogenesis factor 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18634
HGNC: HGNC:8860
Homologene: 242
Wnt7a
Name: wingless-type MMTV integration site family, member 7A
Synonyms: Wnt-7a, tw
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 22421
Homologene: 20969
Wee1
Name: WEE 1 homolog 1 (S. pombe)
Synonyms: Wee1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22390
Homologene: 31152
Stoml1
Name: stomatin-like 1
Synonyms: WPB72, UNC-24, SLP-1, 1810015E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69106
VEGA: 9
Homologene: 31265
Lrp5
Name: low density lipoprotein receptor-related protein 5
Synonyms: LRP7, LR3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16973
HGNC: HGNC:6697
Homologene: 1746
Mtor
Name: mechanistic target of rapamycin kinase
Synonyms: FKBP-rapamycin-associated protein FRAP, 2610315D21Rik, RAPT1, RAFT1, flat, Frap1, mechanistic target of rapamycin (serine/threonine kinase)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56717
HGNC: HGNC:3942
Homologene: 3637
Cep97
Name: centrosomal protein 97
Synonyms: 4932439K18Rik, E130116N02Rik, 2810403B08Rik, Lrriq2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74201
Homologene: 11579
Knl1
Name: kinetochore scaffold 1
Synonyms: 2310043D08Rik, 5730505K17Rik, Casc5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76464
Homologene: 44890
Secisbp2l
Name: SECIS binding protein 2-like
Synonyms: 3110001I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70354
Homologene: 18923
Clock
Name: circadian locomotor output cycles kaput
Synonyms: 5330400M04Rik, KAT13D, bHLHe8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12753
HGNC: HGNC:2082
Homologene: 3603
Ckmt1
Name: creatine kinase, mitochondrial 1, ubiquitous
Synonyms: Mt-CK, mi-CK, UbCKmit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12716
Homologene: 69058
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230895
Homologene: 15583
Sft2d2
Name: SFT2 domain containing 2
Synonyms: cI-45, 2010005O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108735
Homologene: 27069
Adam33
Name: a disintegrin and metallopeptidase domain 33
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 110751
Homologene: 11881
Il20
Name: interleukin 20
Synonyms: Zcyto10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 58181
HGNC: HGNC:6002
Homologene: 10286
Nfatc3
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
Synonyms: NFAT4, NFATx, D8Ertd281e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18021
HGNC: HGNC:7777
Homologene: 27827
Smarcb1
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Synonyms: SNF5/INI1, integrase interactor 1, Baf47, Ini1, Snf5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20587
Homologene: 2310
Peak1
Name: pseudopodium-enriched atypical kinase 1
Synonyms: 1110049L02Rik, NKF3 kinase family member, C230081A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244895
Homologene: 18259
Ndufs1
Name: NADH:ubiquinone oxidoreductase core subunit S1
Synonyms: 9930026A05Rik, 5830412M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227197
HGNC: HGNC:7707
Homologene: 3670
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, D830007G01Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Naip5
Name: NLR family, apoptosis inhibitory protein 5
Synonyms: Naip-rs3, Birc1e, Lgn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17951
HGNC: HGNC:7634
Homologene: 113589
Or51f2
Name: olfactory receptor family 51 subfamily F member 2
Synonyms: GA_x6K02T2PBJ9-5588278-5589228, MOR14-3, MOR14-11, Olfr568
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259095
Homologene: 81595
Arhgef15
Name: Rho guanine nucleotide exchange factor (GEF) 15
Synonyms: D530030K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 442801
Homologene: 18345
Duox2
Name: dual oxidase 2
Synonyms: A430065P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214593
Homologene: 9689
Pcnx
Name: pecanex homolog
Synonyms: 3526401J03Rik, 2900024E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 54604
VEGA: 12
Homologene: 40997
Abcd4
Name: ATP-binding cassette, sub-family D (ALD), member 4
Synonyms: P69r, Pxmp1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19300
VEGA: 12
HGNC: HGNC:68
Homologene: 3703
Tnfrsf8
Name: tumor necrosis factor receptor superfamily, member 8
Synonyms: CD30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21941
Homologene: 949
Fbxo41
Name: F-box protein 41
Synonyms: D6Ertd538e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330369
Homologene: 19837
Neto1
Name: neuropilin (NRP) and tolloid (TLL)-like 1
Synonyms: C130005O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 246317
VEGA: 18
Homologene: 16367
Fam120b
Name: family with sequence similarity 120, member B
Synonyms: CCPG, 4932442K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67544
VEGA: 17
Homologene: 13033
Rmc1
Name: regulator of MON1-CCZ1
Synonyms: 3110002H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 76482
Homologene: 8341
Arhgef40
Name: Rho guanine nucleotide exchange factor (GEF) 40
Synonyms: E130112L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268739
Homologene: 19560
Hif3a
Name: hypoxia inducible factor 3, alpha subunit
Synonyms: MOP7, bHLHe17, Nepas
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 53417
Homologene: 9646
Lamc2
Name: laminin, gamma 2
Synonyms: nicein, 100kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16782
HGNC: HGNC:6493
Homologene: 4062
Sphkap
Name: SPHK1 interactor, AKAP domain containing
Synonyms: A930009L15Rik, 4930544G21Rik, SKIP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 77629
Homologene: 18172
Mex3d
Name: mex3 RNA binding family member D
Synonyms: Rkhd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237400
Homologene: 16890
Aldh3b3
Name: aldehyde dehydrogenase 3 family, member B3
Synonyms: 1700055N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 73458
HGNC: HGNC:410
Homologene: 133295
Crocc2
Name: ciliary rootlet coiled-coil, rootletin family member 2
Synonyms: LOC381284, E030010N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381284
Homologene: 141152
Zfp512b
Name: zinc finger protein 512B
Synonyms: LOC269401, Znf512b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269401
Homologene: 69314
Ajm1
Name: apical junction component 1
Synonyms: LOC381353, Gm996
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381353
Homologene: 19943
Or9g19
Name: olfactory receptor family 9 subfamily G member 19
Synonyms: GA_x6K02T2Q125-47248551-47249468, MOR213-2, Olfr1013
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258757
Homologene: 74096
Plscr1
Name: phospholipid scramblase 1
Synonyms: MmTRA1b, MmTRA1a, NOR1, TRA1, Tras2, Tras1, MuPLSCR2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22038
HGNC: HGNC:9092
Homologene: 41418
Timm10b
Name: translocase of inner mitochondrial membrane 10B
Synonyms: Fracture Callus 1, FxC1, Tim10b, Tim9b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14356
HGNC: HGNC:4022
Homologene: 8142
Lrrc8b
Name: leucine rich repeat containing 8 family, member B
Synonyms: R75581, 2210408K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 433926
Homologene: 9103
Npdc1
Name: neural proliferation, differentiation and control 1
Synonyms: NPDC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18146
HGNC: HGNC:7899
Homologene: 32050
Bcl2l15
Name: BCLl2-like 15
Synonyms: LOC229672, Bfk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229672
Homologene: 19060
Cd5l
Name: CD5 antigen-like
Synonyms: AAC-11, AIM/Spalpha, Sp-alpha, Pdp 1/6, Api6, AIM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11801
HGNC: HGNC:1690
Homologene: 55936
Dcaf5
Name: DDB1 and CUL4 associated factor 5
Synonyms: BCRP2, BCRG2, 9430020B07Rik, Wdr22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320808
VEGA: 12
Homologene: 18564
Cpeb4
Name: cytoplasmic polyadenylation element binding protein 4
Synonyms: 4930447D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67579
Homologene: 12736
Wdr81
Name: WD repeat domain 81
Synonyms: shakey 5, MGC32441, nur5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192652
Homologene: 13983
Arrdc1
Name: arrestin domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 215705
Homologene: 34835
Or5w1b
Name: olfactory receptor family 5 subfamily W member 1B
Synonyms: GA_x6K02T2Q125-49151278-49150337, MOR176-2, Olfr1133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258348
Hcar2
Name: hydroxycarboxylic acid receptor 2
Synonyms: PUMA-G, HM74, Pumag, Gpr109b, Gpr109a, Niacr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 80885
Homologene: 4391
Slc23a4
Name: solute carrier family 23 member 4
Synonyms: LOC243753, 2010107G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243753
Homologene: 134124
Psmb8
Name: proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
Synonyms: Lmp-7, Lmp7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16913
HGNC: HGNC:9545
Homologene: 56499
Whsc1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Ighv1-7
Name: immunoglobulin heavy variable V1-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 668474
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 63,150,059 bp
  • A to T, chromosome 1 at 83,278,285 bp
  • T to A, chromosome 1 at 93,217,853 bp
  • T to C, chromosome 1 at 130,907,428 bp
  • T to C, chromosome 1 at 153,131,890 bp
  • T to C, chromosome 1 at 165,185,088 bp
  • T to C, chromosome 2 at 24,927,828 bp
  • G to A, chromosome 2 at 25,408,945 bp
  • T to C, chromosome 2 at 25,579,264 bp
  • T to C, chromosome 2 at 76,705,820 bp
  • T to C, chromosome 2 at 85,770,269 bp
  • A to T, chromosome 2 at 87,645,229 bp
  • T to C, chromosome 2 at 119,070,352 bp
  • T to A, chromosome 2 at 121,360,592 bp
  • C to T, chromosome 2 at 122,281,455 bp
  • C to T, chromosome 2 at 125,740,737 bp
  • T to G, chromosome 2 at 131,053,442 bp
  • A to G, chromosome 2 at 164,987,221 bp
  • C to T, chromosome 2 at 181,585,668 bp
  • G to T, chromosome 3 at 87,366,107 bp
  • A to G, chromosome 3 at 103,836,062 bp
  • A to T, chromosome 4 at 145,074,882 bp
  • A to T, chromosome 4 at 145,292,633 bp
  • A to G, chromosome 4 at 148,469,006 bp
  • G to A, chromosome 5 at 76,230,338 bp
  • T to A, chromosome 5 at 105,480,297 bp
  • T to A, chromosome 5 at 123,864,469 bp
  • T to C, chromosome 6 at 34,957,022 bp
  • A to G, chromosome 6 at 85,484,504 bp
  • A to C, chromosome 6 at 91,394,655 bp
  • T to C, chromosome 7 at 17,050,655 bp
  • A to C, chromosome 7 at 102,877,797 bp
  • G to C, chromosome 7 at 105,641,122 bp
  • TCCCC to TCCC, chromosome 7 at 110,124,569 bp
  • C to T, chromosome 8 at 25,679,969 bp
  • T to C, chromosome 8 at 106,079,057 bp
  • T to C, chromosome 9 at 56,257,774 bp
  • C to A, chromosome 9 at 58,253,370 bp
  • A to G, chromosome 9 at 92,266,424 bp
  • A to T, chromosome 10 at 19,888,737 bp
  • G to A, chromosome 10 at 75,904,418 bp
  • T to C, chromosome 10 at 80,382,594 bp
  • A to G, chromosome 11 at 31,889,877 bp
  • T to C, chromosome 11 at 62,338,234 bp
  • G to A, chromosome 11 at 68,954,051 bp
  • A to T, chromosome 11 at 75,445,906 bp
  • G to A, chromosome 12 at 80,397,752 bp
  • T to A, chromosome 12 at 81,917,730 bp
  • T to C, chromosome 12 at 84,617,302 bp
  • A to G, chromosome 12 at 114,538,881 bp
  • A to G, chromosome 13 at 44,896,290 bp
  • C to A, chromosome 13 at 100,230,662 bp
  • C to A, chromosome 14 at 51,994,338 bp
  • T to C, chromosome 16 at 55,915,583 bp
  • C to T, chromosome 17 at 15,403,082 bp
  • A to G, chromosome 17 at 34,138,001 bp
  • T to C, chromosome 17 at 34,201,240 bp
  • T to C, chromosome 18 at 12,171,583 bp
  • A to G, chromosome 18 at 86,498,643 bp
  • A to G, chromosome 19 at 3,622,512 bp
  • C to T, chromosome 19 at 3,968,522 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5632 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043283-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.