Strain Name:
C57BL/6J-MtgxR5656Btlr
Stock Number:
043302-MU
Citation ID:
RRID:MMRRC_043302-MU
Other Names:
R5656 (G1)
Major Collection:

Gene Information

Pzp
Name: PZP, alpha-2-macroglobulin like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11287
Homologene: 104112
P2rx7
Name: purinergic receptor P2X, ligand-gated ion channel, 7
Synonyms: P2X7R, P2X(7), P2X7 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18439
HGNC: HGNC:8537
Homologene: 1925
Mta1
Name: metastasis associated 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 116870
HGNC: HGNC:7410
Homologene: 3442
Rapgef6
Name: Rap guanine nucleotide exchange factor (GEF) 6
Synonyms: PDZ-GEF2, C030018K18Rik, RA-GEF-2, Pdzgef2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192786
Homologene: 22968
Sec23ip
Name: Sec23 interacting protein
Synonyms: D7Ertd373e, p125
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 207352
Homologene: 38288
Sptlc2
Name: serine palmitoyltransferase, long chain base subunit 2
Synonyms: LCB2, Spt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20773
Homologene: 21610
Gtf3c1
Name: general transcription factor III C 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233863
HGNC: HGNC:4664
Homologene: 31040
Smg1
Name: SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
Synonyms: 2610207I05Rik, 5430435M13Rik, C130002K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233789
Homologene: 56697
Atg2b
Name: autophagy related 2B
Synonyms: C030004M05Rik, 2410024A21Rik, C630028L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 76559
VEGA: 12
Homologene: 9974
Slu7
Name: SLU7 splicing factor homolog (S. cerevisiae)
Synonyms: D11Ertd730e, D3Bwg0878e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 193116
Homologene: 4690
Ncapd3
Name: non-SMC condensin II complex, subunit D3
Synonyms: B130055D15Rik, 4632407J06Rik, 2810487N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 78658
VEGA: 9
Homologene: 41021
Ddx18
Name: DEAD box helicase 18
Synonyms: 2310005B10Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66942
HGNC: HGNC:2741
Homologene: 6697
Tmem43
Name: transmembrane protein 43
Synonyms: 1200015A22Rik, LUMA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74122
Homologene: 11532
Melk
Name: maternal embryonic leucine zipper kinase
Synonyms: MPK38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 17279
Homologene: 32111
Efs
Name: embryonal Fyn-associated substrate
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13644
VEGA: 14
Homologene: 4284
Ppfia1
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
Synonyms: Liprin-alpha1, C030014K08Rik, liprin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233977
HGNC: HGNC:9245
Homologene: 20802
Iqcd
Name: IQ motif containing D
Synonyms: 4933433C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75732
Homologene: 49921
Sv2a
Name: synaptic vesicle glycoprotein 2 a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 64051
Homologene: 32237
Zfp644
Name: zinc finger protein 644
Synonyms: 1110068L01Rik, Zep-2, D5Ertd689e, BM-005
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 52397
Homologene: 12971
Bub1b
Name: BUB1B, mitotic checkpoint serine/threonine kinase
Synonyms: BUBR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12236
HGNC: HGNC:1149
Homologene: 933
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, Odz3, 2610100B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23965
Homologene: 22673
Naa35
Name: N(alpha)-acetyltransferase 35, NatC auxiliary subunit
Synonyms: A330027C19Rik, C030004C14Rik, Mak10, A330021G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 78689
Homologene: 5781
Prdm10
Name: PR domain containing 10
Synonyms: LOC382066, tristanin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382066
Homologene: 45718
Cd68
Name: CD68 antigen
Synonyms: macrosialin, gp110, Scard1, Lamp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12514
HGNC: HGNC:1693
Homologene: 955
Cd22
Name: CD22 antigen
Synonyms: Lyb8, Lyb-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12483
HGNC: HGNC:1643
Homologene: 31052
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: Dnahc5, b2b1565Clo, b2b1537Clo, b2b1154Clo, b2b1134Clo, Mdnah5, b2b3491Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Ttn
Name: titin
Synonyms: connectin, 2310074I15Rik, mdm, D830007G01Rik, 1100001C23Rik, D330041I19Rik, shru, 2310057K23Rik, L56, 2310036G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Nav3
Name: neuron navigator 3
Synonyms: POMFIL1, 4732483H20Rik, Pomfil1p, unc53H3, steerin 3, 9630020C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 260315
Homologene: 56688
Clca3a2
Name: chloride channel accessory 3A2
Synonyms: Clca2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80797
Homologene: 77224
Pwwp2b
Name: PWWP domain containing 2B
Synonyms: D930023J19Rik, Pwwp2, D7Ertd517e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101631
Homologene: 19056
Map6
Name: microtubule-associated protein 6
Synonyms: F-STOP, Mtap6, STOP, 2810411E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17760
HGNC: HGNC:6868
Homologene: 7850
Mast3
Name: microtubule associated serine/threonine kinase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 546071
Homologene: 66191
Gxylt1
Name: glucoside xylosyltransferase 1
Synonyms: LOC223827, Glt8d3, LOC382997
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223827
Homologene: 28259
Mbd6
Name: methyl-CpG binding domain protein 6
Synonyms: D10Wsu93e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 110962
Homologene: 14171
4933405L10Rik
Name: RIKEN cDNA 4933405L10 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71046
Homologene: 19274
Shank1
Name: SH3 and multiple ankyrin repeat domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243961
Homologene: 22949
Vsig10l
Name: V-set and immunoglobulin domain containing 10 like
Synonyms: 2210412E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 75690
Homologene: 35386
Zbtb46
Name: zinc finger and BTB domain containing 46
Synonyms: 4933406L05Rik, 2610019F01Rik, Btbd4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72147
Homologene: 81908
Gucy1b2
Name: guanylate cyclase 1, soluble, beta 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239134
HGNC: HGNC:4686
Homologene: 136630
Ublcp1
Name: ubiquitin-like domain containing CTD phosphatase 1
Synonyms: 8430435I17Rik, 4930527B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 79560
Homologene: 16796
Eci1
Name: enoyl-Coenzyme A delta isomerase 1
Synonyms: Dci, eci
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13177
VEGA: 17
HGNC: HGNC:2703
Homologene: 37554
Nlrp4f
Name: NLR family, pyrin domain containing 4F
Synonyms: C330026N02Rik, Nalp4f, Nalp-kappa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 97895
VEGA: 13
Homologene: 87252
Fbp1
Name: fructose bisphosphatase 1
Synonyms: FBPase brain isoform, FBPase liver, Fbp-2, Fbp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14121
HGNC: HGNC:3606
Homologene: 55467
Phactr2
Name: phosphatase and actin regulator 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215789
Homologene: 8816
Setdb2
Name: SET domain, bifurcated 2
Synonyms: KMT1F, LOC239122
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239122
Homologene: 12903
Vmn1r29
Name: vomeronasal 1 receptor 29
Synonyms: V1rc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113859
Homologene: 123821
Cpa6
Name: carboxypeptidase A6
Synonyms: 9030616D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329093
Homologene: 75130
Olfr397
Name: olfactory receptor 397
Synonyms: GA_x6K02T2P1NL-4121434-4122381, MOR135-28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258343
Homologene: 138309
Sult1c1
Name: sulfotransferase family, cytosolic, 1C, member 1
Synonyms: (PST)G, P-SULT, Stp2, Sult1a2, mOLFST
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20888
Homologene: 56817
Olfr1480
Name: olfactory receptor 1480
Synonyms: GA_x6K02T2RE5P-3862389-3863336, MOR202-44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 404339
Homologene: 110492
Adrb3
Name: adrenergic receptor, beta 3
Synonyms: Beta-3 AR, Adrb-3, beta3-adrenergic receptor, beta 3-AR, Beta-3 adrenoceptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11556
HGNC: HGNC:288
Homologene: 37250
Olfr497
Name: olfactory receptor 497
Synonyms: GA_x6K02T2PBJ9-10752603-10753547, MOR204-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258733
Homologene: 133602
Sra1
Name: steroid receptor RNA activator 1
Synonyms: Srap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 24068
Homologene: 11906
Phc3
Name: polyhomeotic 3
Synonyms: HPH3, EDR3, E030046K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 241915
Homologene: 69390
Tbc1d22b
Name: TBC1 domain family, member 22B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 381085
Homologene: 23043
Usp17ld
Name: ubiquitin specific peptidase 17-like D
Synonyms: Dub2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 384701
Homologene: 131315
Trbv13-2
Name: T cell receptor beta, variable 13-2
Synonyms: Tcrb-V8.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100124675
Klhl41
Name: kelch-like 41
Synonyms: Kbtbd10, LOC228003
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228003
Homologene: 4421
Gm29096
Name: predicted gene 29096
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Gltscr1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Fam178a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 10,329,514 bp
  • A to T, chromosome 1 at 121,561,358 bp
  • T to A, chromosome 2 at 69,683,532 bp
  • T to G, chromosome 2 at 76,774,654 bp
  • T to A, chromosome 2 at 118,605,431 bp
  • A to G, chromosome 2 at 181,423,417 bp
  • G to T, chromosome 3 at 30,965,866 bp
  • A to G, chromosome 3 at 96,185,572 bp
  • A to T, chromosome 3 at 144,797,632 bp
  • A to G, chromosome 4 at 44,312,237 bp
  • A to G, chromosome 5 at 106,637,982 bp
  • A to G, chromosome 5 at 120,605,126 bp
  • A to T, chromosome 5 at 122,673,717 bp
  • T to A, chromosome 6 at 41,121,694 bp
  • T to A, chromosome 6 at 58,308,167 bp
  • T to C, chromosome 6 at 91,480,708 bp
  • T to C, chromosome 6 at 128,490,072 bp
  • T to G, chromosome 7 at 30,869,773 bp
  • C to T, chromosome 7 at 43,464,151 bp
  • T to C, chromosome 7 at 44,352,886 bp
  • A to G, chromosome 7 at 99,336,298 bp
  • A to G, chromosome 7 at 103,250,840 bp
  • A to G, chromosome 7 at 108,422,618 bp
  • A to T, chromosome 7 at 118,154,664 bp
  • T to A, chromosome 7 at 125,662,654 bp
  • A to G, chromosome 7 at 128,776,784 bp
  • T to A, chromosome 7 at 139,255,971 bp
  • A to T, chromosome 7 at 144,519,974 bp
  • T to C, chromosome 8 at 27,227,377 bp
  • T to C, chromosome 8 at 48,228,762 bp
  • T to C, chromosome 8 at 70,786,221 bp
  • A to G, chromosome 8 at 105,709,512 bp
  • T to A, chromosome 9 at 27,051,645 bp
  • C to T, chromosome 9 at 31,353,417 bp
  • T to C, chromosome 10 at 13,388,703 bp
  • A to G, chromosome 10 at 41,569,934 bp
  • A to C, chromosome 10 at 109,764,633 bp
  • A to T, chromosome 10 at 127,285,286 bp
  • A to G, chromosome 11 at 43,443,418 bp
  • A to G, chromosome 11 at 44,465,606 bp
  • A to G, chromosome 11 at 54,636,136 bp
  • T to A, chromosome 11 at 69,664,421 bp
  • T to A, chromosome 11 at 73,964,710 bp
  • A to T, chromosome 12 at 87,346,761 bp
  • A to G, chromosome 12 at 105,621,328 bp
  • T to C, chromosome 12 at 113,123,139 bp
  • G to A, chromosome 13 at 59,622,866 bp
  • C to A, chromosome 13 at 62,875,196 bp
  • G to A, chromosome 13 at 65,190,871 bp
  • T to C, chromosome 14 at 54,917,127 bp
  • T to C, chromosome 14 at 59,419,118 bp
  • T to C, chromosome 14 at 62,422,981 bp
  • A to G, chromosome 15 at 28,421,064 bp
  • A to T, chromosome 15 at 93,245,661 bp
  • T to A, chromosome 17 at 24,437,309 bp
  • A to G, chromosome 17 at 29,594,780 bp
  • G to A, chromosome 17 at 46,808,369 bp
  • T to C, chromosome 17 at 53,964,652 bp
  • A to G, chromosome 18 at 36,678,407 bp
  • A to G, chromosome 19 at 13,530,380 bp
  • T to A, chromosome 19 at 44,973,235 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5656 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043302-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.