Strain Name:
C57BL/6J-MtgxR5662Btlr
Stock Number:
043305-MU
Citation ID:
RRID:MMRRC_043305-MU
Other Names:
R5662 (G1)
Major Collection:

Gene Information

Kif3c
Name: kinesin family member 3C
Synonyms: N-4 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 16570
VEGA: 12
HGNC: HGNC:6321
Homologene: 55640
Fam3c
Name: family with sequence similarity 3, member C
Synonyms: D6Wsu176e, Fam3c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 27999
Homologene: 8926
Cers2
Name: ceramide synthase 2
Synonyms: Lass2, Trh3, 0610013I17Rik, CerS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 76893
Homologene: 39581
Ssc4d
Name: scavenger receptor cysteine rich family, 4 domains
Synonyms: C330016E03Rik, Srcrb4d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 109267
Homologene: 34137
Eprs
Name: glutamyl-prolyl-tRNA synthetase
Synonyms: 2410081F06Rik, 3010002K18Rik, Qprs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 107508
HGNC: HGNC:3418
Homologene: 5870
Zfp638
Name: zinc finger protein 638
Synonyms: Zfml, Np220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 18139
Homologene: 7447
Srebf2
Name: sterol regulatory element binding factor 2
Synonyms: lop13, bHLHd2, nuc, SREBP2, SREBP2gc, SREBP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 20788
VEGA: 15
Homologene: 20966
Ubr7
Name: ubiquitin protein ligase E3 component n-recognin 7 (putative)
Synonyms: 5730410I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 66622
VEGA: 12
Homologene: 11998
Dennd4c
Name: DENN/MADD domain containing 4C
Synonyms: 1700065A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 329877
Homologene: 23057
Xdh
Name: xanthine dehydrogenase
Synonyms: xanthine oxidase, Xox-1, XO, Xox1, Xor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 22436
VEGA: 17
Homologene: 324
Dhx8
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 8
Synonyms: mDEAH6, Ddx8, RNA helicase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217207
HGNC: HGNC:2749
Homologene: 3628
Sun2
Name: Sad1 and UNC84 domain containing 2
Synonyms: Unc84b, B230369L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223697
Homologene: 9113
Spink6
Name: serine peptidase inhibitor, Kazal type 6
Synonyms: EG433180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 433180
VEGA: 18
Homologene: null
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Smarcb1
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Synonyms: Baf47, Snf5, Ini1, SNF5/INI1, integrase interactor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 20587
Homologene: 2310
Paxbp1
Name: PAX3 and PAX7 binding protein 1
Synonyms: Gcfc1, 1810007M14Rik, Pax3/7bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 67367
Homologene: 9604
Pnpla7
Name: patatin-like phospholipase domain containing 7
Synonyms: E430013P11Rik, NRE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241274
Homologene: 62431
D430042O09Rik
Name: RIKEN cDNA D430042O09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233865
Homologene: 45841
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC, NBC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54403
Homologene: 55776
Slc45a2
Name: solute carrier family 45, member 2
Synonyms: Oca4, bls, Matp, Aim1, Dbr, blanc-sale, Aim-1, dominant brown
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 22293
Homologene: 9412
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hy-3, hy3, 1700034M11Rik, hyrh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244653
Homologene: 52118
Mroh4
Name: maestro heat-like repeat family member 4
Synonyms: 1700016M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 69439
Homologene: 72545
Slc26a6
Name: solute carrier family 26, member 6
Synonyms: Pat1, CFEX, B930010B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 171429
Homologene: 99903
Ly75
Name: lymphocyte antigen 75
Synonyms: CD205, DEC-205
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17076
HGNC: HGNC:6729
Homologene: 31085
Col6a4
Name: collagen, type VI, alpha 4
Synonyms: Dvwa, Vwa6, EG235580, 1110001D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 68553
HGNC: null
Homologene: 130754
Itga1
Name: integrin alpha 1
Synonyms: CD49A, E130012M19Rik, Vla1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 109700
VEGA: 13
HGNC: HGNC:6134
Homologene: 57137
Ctsf
Name: cathepsin F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 56464
VEGA: 19
HGNC: HGNC:2531
Homologene: 31194
Olfr466
Name: olfactory receptor 466
Synonyms: GA_x6K02T2PB7A-3051266-3052192, MOR209-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 258816
HGNC: null
Homologene: 72032
Acan
Name: aggrecan
Synonyms: Agc1, b2b183Clo, Cspg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11595
HGNC: HGNC:319
Homologene: 137204
Igtp
Name: interferon gamma induced GTPase
Synonyms: Irgm3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16145
HGNC: null
Homologene: 23118
Olfr24
Name: olfactory receptor 24
Synonyms: MOR132-1, GA_x6K02T2PVTD-12498544-12497603, MTPCR51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 18322
HGNC: HGNC:8220
Homologene: 64896
Ccdc186
Name: coiled-coil domain containing 186
Synonyms: A630007B06Rik, 1810028B20Rik, Otg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 213993
Homologene: 9963
Lrrc34
Name: leucine rich repeat containing 34
Synonyms: 1700007J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71827
Homologene: 27419
Pom121l2
Name: POM121 membrane glycoprotein-like 2 (rat)
Synonyms: LOC195236
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 195236
Homologene: 123536
Klhdc1
Name: kelch domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 271005
Homologene: 18155
Slc25a11
Name: solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11
Synonyms: 2310022P18Rik, 2oxoc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67863
Homologene: 2637
Olfr384
Name: olfactory receptor 384
Synonyms: Olfr386, GA_x6K02T2P1NL-3739520-3740032, GA_x6K02T2P1NL-3773152-3774090, MOR135-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 193053
HGNC: null
Homologene: 105206
Ephb4
Name: Eph receptor B4
Synonyms: Tyro11, Htk, Myk1, b2b2412Clo, MDK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 13846
HGNC: HGNC:3395
Homologene: 20939
Ankrd54
Name: ankyrin repeat domain 54
Synonyms: C730048E16Rik, Liar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223690
Homologene: 16352
Olfr811
Name: olfactory receptor 811
Synonyms: MOR110-6, GA_x6K02T2PULF-11481207-11480248
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258545
HGNC: null
Homologene: 133725
Nutm1
Name: NUT midline carcinoma, family member 1
Synonyms: Nut, BC125332
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 213765
Homologene: 18185
Acsm4
Name: acyl-CoA synthetase medium-chain family member 4
Synonyms: OMACS, O-MACS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233801
Homologene: 72281
Sult2a8
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8
Synonyms: 2810007J24Rik, mL-STL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76971
Homologene: null
Wdr55
Name: WD repeat domain 55
Synonyms: 2410080P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 67936
VEGA: 18
Homologene: 9789
Gpr132
Name: G protein-coupled receptor 132
Synonyms: G2a, G2 accumulation
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 56696
VEGA: 12
Homologene: 8350
Serpine3
Name: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
Synonyms: E130113E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 319433
VEGA: 14
Homologene: 53117
Ighv1-49
Name: immunoglobulin heavy variable 1-49
Synonyms: Gm16830
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 629925
HGNC: null
Homologene: null
Fam65c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
Wbscr17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
Gm10645
Name: predicted gene 10645
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: null
VEGA: null
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 185,394,425 bp
  • A to G, chromosome 2 at 25,052,384 bp
  • G to A, chromosome 2 at 60,352,381 bp
  • T to C, chromosome 2 at 112,249,300 bp
  • T to G, chromosome 2 at 167,993,556 bp
  • T to C, chromosome 3 at 30,631,324 bp
  • C to T, chromosome 3 at 95,320,984 bp
  • C to T, chromosome 4 at 86,795,288 bp
  • C to T, chromosome 5 at 89,028,244 bp
  • G to A, chromosome 5 at 131,086,006 bp
  • A to G, chromosome 5 at 135,960,894 bp
  • A to T, chromosome 5 at 137,372,195 bp
  • T to C, chromosome 6 at 22,355,062 bp
  • T to A, chromosome 6 at 83,943,129 bp
  • C to T, chromosome 7 at 14,427,840 bp
  • T to A, chromosome 7 at 79,100,107 bp
  • T to G, chromosome 7 at 119,694,800 bp
  • A to G, chromosome 7 at 125,842,703 bp
  • A to G, chromosome 8 at 83,165,857 bp
  • T to G, chromosome 8 at 110,580,709 bp
  • A to G, chromosome 9 at 18,755,600 bp
  • C to G, chromosome 9 at 106,068,001 bp
  • G to A, chromosome 9 at 108,859,339 bp
  • T to C, chromosome 10 at 75,904,570 bp
  • T to C, chromosome 10 at 129,802,307 bp
  • A to G, chromosome 11 at 58,206,279 bp
  • G to A, chromosome 11 at 70,645,419 bp
  • T to C, chromosome 11 at 73,603,179 bp
  • A to G, chromosome 11 at 101,766,758 bp
  • T to A, chromosome 12 at 3,367,031 bp
  • T to A, chromosome 12 at 69,283,165 bp
  • T to C, chromosome 12 at 102,768,267 bp
  • G to A, chromosome 12 at 112,852,796 bp
  • A to T, chromosome 12 at 115,055,407 bp
  • T to C, chromosome 13 at 21,982,188 bp
  • T to C, chromosome 13 at 65,152,253 bp
  • C to T, chromosome 13 at 114,986,171 bp
  • T to G, chromosome 14 at 62,670,842 bp
  • A to G, chromosome 15 at 11,022,083 bp
  • A to T, chromosome 15 at 74,625,428 bp
  • A to G, chromosome 15 at 79,062,614 bp
  • C to T, chromosome 15 at 79,738,868 bp
  • T to C, chromosome 15 at 82,195,003 bp
  • G to A, chromosome 16 at 91,037,397 bp
  • A to G, chromosome 17 at 30,737,333 bp
  • C to T, chromosome 17 at 73,941,115 bp
  • G to A, chromosome 18 at 36,760,395 bp
  • C to A, chromosome 18 at 44,074,414 bp
  • T to C, chromosome 19 at 4,856,578 bp
  • A to G, chromosome 19 at 56,793,488 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5662 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043305-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.