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Strain Name:
C57BL/6J-MtgxR5664Btlr/Mmmh
Stock Number:
043307-MU
Citation ID:
RRID:MMRRC_043307-MU
Other Names:
R5664 (G1)
Major Collection:

Strain Information

Pkd1
Name: polycystin 1, transient receptor potential channel interacting
Synonyms: polycystin-1, PC1, PC-1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18763
VEGA: 17
HGNC: HGNC:9008
Homologene: 250
Frem2
Name: Fras1 related extracellular matrix protein 2
Synonyms: 8430406N05Rik, 6030440P17Rik, my, ne, b2b1562Clo
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242022
Homologene: 18454
Mthfr
Name: methylenetetrahydrofolate reductase
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17769
HGNC: HGNC:7436
Homologene: 4349
Map7
Name: microtubule-associated protein 7
Synonyms: E-MAP-115, mste, ste, mshi, Mtap7
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17761
VEGA: 10
HGNC: HGNC:6869
Homologene: 20851
Atr
Name: ataxia telangiectasia and Rad3 related
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245000
HGNC: HGNC:882
Homologene: 96916
Nomo1
Name: nodal modulator 1
Synonyms: PM5, Nomo, D7Ertd156e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 211548
Homologene: 13810
Nup133
Name: nucleoporin 133
Synonyms: 4832420O05Rik, mermaid
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234865
Homologene: 32402
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
Snhg16
Name: small nucleolar RNA host gene 16
Synonyms: 1810032O08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66293
Ank3
Name: ankyrin 3, epithelial
Synonyms: Ank-3, Ankyrin-3, AnkG, 2900054D09Rik, Ankyrin-G
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Wap
Name: whey acidic protein
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22373
Homologene: 137242
Dhx8
Name: DEAH-box helicase 8
Synonyms: mDEAH6, RNA helicase, Ddx8
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217207
HGNC: HGNC:2749
Homologene: 3628
Atp6v1b2
Name: ATPase, H+ transporting, lysosomal V1 subunit B2
Synonyms: HO57, Atp6b2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11966
HGNC: HGNC:854
Homologene: 1279
Trak1
Name: trafficking protein, kinesin binding 1
Synonyms: 2310001H13Rik, hyrt
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67095
Homologene: 25103
C2cd2l
Name: C2 calcium-dependent domain containing 2-like
Synonyms: 1300006O23Rik, Tmem24
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71764
VEGA: 9
Homologene: 8876
Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Synonyms: acetyl-CoA carboxylase, Acc1, LOC327983, Acac, A530025K05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 107476
HGNC: HGNC:84
Homologene: 31015
Gcat
Name: glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)
Synonyms: Kbl, aminoacetone synthase
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 26912
VEGA: 15
HGNC: HGNC:4188
Homologene: 8475
9430015G10Rik
Name: RIKEN cDNA 9430015G10 gene
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230996
Homologene: 51678
Nktr
Name: natural killer tumor recognition sequence
Synonyms: D9Wsu172e, 5330401F18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18087
HGNC: HGNC:7833
Homologene: 122148
Pnpla6
Name: patatin-like phospholipase domain containing 6
Synonyms: Swiss-cheese, MSws, Nte
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 50767
Homologene: 21333
Qser1
Name: glutamine and serine rich 1
Synonyms: 4732486I23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99003
Homologene: 11710
Dhx29
Name: DExH-box helicase 29
Synonyms: E130202M19Rik, DEAH (Asp-Glu-Ala-His) box polypeptide 29
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218629
VEGA: 13
Homologene: 10387
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC, NBC1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 54403
Homologene: 55776
Krt74
Name: keratin 74
Synonyms: Kb37
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 406222
VEGA: 15
Col13a1
Name: collagen, type XIII, alpha 1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12817
HGNC: HGNC:2190
Homologene: 22421
Epha5
Name: Eph receptor A5
Synonyms: Cek7, bsk, Els1, Rek7, Hek7, Ehk1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13839
HGNC: HGNC:3389
Homologene: 55824
Pik3c2g
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18705
HGNC: HGNC:8973
Homologene: 3362
Avl9
Name: AVL9 cell migration associated
Synonyms: D730049P16Rik, 5830411G16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78937
Homologene: 62425
Glt6d1
Name: glycosyltransferase 6 domain containing 1
Synonyms: 4933411C14Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71103
Homologene: 18826
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Tbx3
Name: T-box 3
Synonyms: D5Ertd189e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 21386
Homologene: 4371
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: bl, E130113P14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231470
Homologene: 23516
Capn3
Name: calpain 3
Synonyms: Capa-3, Capa3, Lp82, p94
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12335
HGNC: HGNC:1480
Homologene: 52
Gimap6
Name: GTPase, IMAP family member 6
Synonyms: 4833419H03Rik, Ian6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 231931
Homologene: 11670
Mrpl37
Name: mitochondrial ribosomal protein L37
Synonyms: MRP-L2, Rpml2, 2300004O14Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56280
Homologene: 9536
Thbs2
Name: thrombospondin 2
Synonyms: TSP2, Thbs-2, Thrombospondin-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21826
VEGA: 17
Homologene: 2438
Clcf1
Name: cardiotrophin-like cytokine factor 1
Synonyms: NNT-1/BSF-3, CLC, Bsf3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 56708
Homologene: 8299
Zfp235
Name: zinc finger protein 235
Synonyms: 0610030O19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56525
Homologene: 122146
Sla2
Name: Src-like-adaptor 2
Synonyms: SLAP-2, SLAP2, A930009E21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 77799
Homologene: 49989
Brme1
Name: break repair meiotic recombinase recruitment factor 1
Synonyms: Meiok21, 4930432K21Rik, Mamerr
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74666
Homologene: 11525
Hpx
Name: hemopexin
Synonyms: hx, Hpxn
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15458
HGNC: HGNC:5171
Homologene: 511
Tsks
Name: testis-specific serine kinase substrate
Synonyms: clone 4, Tssks1, Tsks, Stk22s1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22116
Homologene: 7984
Pcdhb14
Name: protocadherin beta 14
Synonyms: Pcdhb17, PcdhbN, 2210006M07Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93885
Homologene: 70876
Prss1l
Name: serine protease 1 (trypsin 1) like
Synonyms: Gm5771
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 436523
Homologene: 88408
Serpina6
Name: serine (or cysteine) peptidase inhibitor, clade A, member 6
Synonyms: Cbg
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 12401
HGNC: HGNC:1540
Homologene: 20417
Herc6
Name: hect domain and RLD 6
Synonyms: 4930427L17Rik, 1700121D12Rik, CEB1, 2510038N07Rik, Herc5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67138
Homologene: 70768
Loxl3
Name: lysyl oxidase-like 3
Synonyms: Lor2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16950
Homologene: 56591
Vcpip1
Name: valosin containing protein (p97)/p47 complex interacting protein 1
Synonyms: 5730421J18Rik, 5730538E15Rik, Vcip135
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70675
Homologene: 11814
Vmn2r68
Name: vomeronasal 2, receptor 68
Synonyms: EG620697, Vmn2r68-ps
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 620697
Homologene: 115466
Epsti1
Name: epithelial stromal interaction 1
Synonyms: 5033415K03Rik, BRESI1, 2310046K10Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 108670
VEGA: 14
Homologene: 12630
Vmn2r118
Name: vomeronasal 2, receptor 118
Synonyms: EG668547, Vmn2r119, EG383258
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 383258
Homologene: 129687
Or4b12
Name: olfactory receptor family 4 subfamily B member 12
Synonyms: GA_x6K02T2Q125-51620802-51619885, MOR227-5, Olfr1271
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258789
HGNC: HGNC:8290
Edil3
Name: EGF-like repeats and discoidin I-like domains 3
Synonyms: Del1, developmental endothelial locus-1, Del-1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 13612
HGNC: HGNC:3173
Homologene: 21166
Inf2
Name: inverted formin, FH2 and WH2 domain containing
Synonyms: EG629699, 2610204M08Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 70435
VEGA: 12
Homologene: 82406
Vmn2r76
Name: vomeronasal 2, receptor 76
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 675969
Homologene: 104330
Ccl3
Name: C-C motif chemokine ligand 3
Synonyms: MIP1-(a), MIP1-alpha, MIP-1 alpha, MIP-1alpha, macrophage inflammatory protein-1alpha, Mip1a, CCL3, Scya3, LD78alpha, G0S19-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20302
Homologene: 2242
Arsj
Name: arylsulfatase J
Synonyms: 9330196J05Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 271970
Homologene: 35257
Vmn2r23
Name: vomeronasal 2, receptor 23
Synonyms: EG435916
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 435916
Homologene: 135826
Dkk1
Name: dickkopf WNT signaling pathway inhibitor 1
Synonyms: mdkk-1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13380
HGNC: HGNC:2891
Homologene: 7689
Or5w22
Name: olfactory receptor family 5 subfamily W member 22
Synonyms: V5, Olfr4-2, GA_x6K02T2Q125-49033418-49034341, MOR177-5, Olfr153
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 110511
Homologene: 128127
Ppl
Name: periplakin
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19041
VEGA: 16
HGNC: HGNC:9273
Homologene: 2026
Gjb5
Name: gap junction protein, beta 5
Synonyms: Cnx31.1, connexin 31.1, Gjb-5, Cx31.1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14622
HGNC: HGNC:4287
Homologene: 3858
Plp2rt
Name: proteolipid protein 2, retrotransposed
Synonyms: Gm6169, Prp2rt
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 620648
VEGA: 13
HGNC: HGNC:9087
Gtf2h5
Name: general transcription factor IIH, polypeptide 5
Synonyms: 2700017P07Rik, 2810432H05Rik, D17Wsu155e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66467
Homologene: 45635
Tdpoz6
Name: TD and POZ domain containing 6
Synonyms: Gm37596, Gm9107
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 668325
Prune
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
0610030E20Rik
Name: RIKEN cDNA 0610030E20 gene
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68364
Homologene: 19243
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 9,746,379 bp
  • T to C, chromosome 2 at 25,814,180 bp
  • T to A, chromosome 2 at 82,988,095 bp
  • T to C, chromosome 2 at 87,532,834 bp
  • A to G, chromosome 2 at 90,265,615 bp
  • A to T, chromosome 2 at 104,778,196 bp
  • G to A, chromosome 2 at 120,477,025 bp
  • A to T, chromosome 2 at 156,874,999 bp
  • A to G, chromosome 3 at 53,652,490 bp
  • A to G, chromosome 3 at 93,692,687 bp
  • A to T, chromosome 3 at 95,258,178 bp
  • A to T, chromosome 3 at 126,438,657 bp
  • T to C, chromosome 4 at 107,064,391 bp
  • T to A, chromosome 4 at 127,355,929 bp
  • T to C, chromosome 4 at 148,055,466 bp
  • T to A, chromosome 4 at 156,123,559 bp
  • T to A, chromosome 5 at 84,331,866 bp
  • C to T, chromosome 5 at 89,028,244 bp
  • T to C, chromosome 5 at 96,728,535 bp
  • A to G, chromosome 5 at 119,678,731 bp
  • C to T, chromosome 6 at 41,394,671 bp
  • T to C, chromosome 6 at 48,702,275 bp
  • T to C, chromosome 6 at 56,753,839 bp
  • C to A, chromosome 6 at 57,618,684 bp
  • T to A, chromosome 6 at 72,348,994 bp
  • G to A, chromosome 6 at 83,049,882 bp
  • C to T, chromosome 6 at 123,713,074 bp
  • T to C, chromosome 6 at 139,737,007 bp
  • A to C, chromosome 7 at 24,142,151 bp
  • A to T, chromosome 7 at 31,099,262 bp
  • G to A, chromosome 7 at 44,953,784 bp
  • A to G, chromosome 7 at 46,076,157 bp
  • A to T, chromosome 7 at 85,233,770 bp
  • A to G, chromosome 7 at 86,245,994 bp
  • A to T, chromosome 7 at 105,595,148 bp
  • A to G, chromosome 8 at 3,537,478 bp
  • A to G, chromosome 8 at 69,107,620 bp
  • A to G, chromosome 8 at 71,359,882 bp
  • A to T, chromosome 8 at 84,166,659 bp
  • T to C, chromosome 8 at 123,906,281 bp
  • T to C, chromosome 9 at 44,313,772 bp
  • C to A, chromosome 9 at 95,905,813 bp
  • T to A, chromosome 9 at 121,472,307 bp
  • T to A, chromosome 9 at 121,749,417 bp
  • T to A, chromosome 10 at 20,267,359 bp
  • T to C, chromosome 10 at 61,851,116 bp
  • G to A, chromosome 10 at 70,002,565 bp
  • A to G, chromosome 11 at 6,638,609 bp
  • A to G, chromosome 11 at 83,649,213 bp
  • T to C, chromosome 11 at 84,243,384 bp
  • A to T, chromosome 11 at 101,740,751 bp
  • A to T, chromosome 11 at 107,073,699 bp
  • A to T, chromosome 11 at 116,672,664 bp
  • A to C, chromosome 12 at 103,654,467 bp
  • A to G, chromosome 12 at 112,611,728 bp
  • G to T, chromosome 13 at 89,319,713 bp
  • C to A, chromosome 13 at 97,099,121 bp
  • T to A, chromosome 13 at 112,946,879 bp
  • C to T, chromosome 14 at 77,963,664 bp
  • T to A, chromosome 15 at 79,043,073 bp
  • A to G, chromosome 15 at 101,760,579 bp
  • T to C, chromosome 16 at 5,106,055 bp
  • G to A, chromosome 17 at 6,084,524 bp
  • A to T, chromosome 17 at 14,689,837 bp
  • A to T, chromosome 17 at 24,569,371 bp
  • A to G, chromosome 17 at 55,592,765 bp
  • T to A, chromosome 18 at 37,448,996 bp
  • T to C, chromosome 19 at 4,222,096 bp
  • T to A, chromosome 19 at 30,548,789 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5664 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043307-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.