Strain Name:
C57BL/6J-MtgxR5688Btlr/Mmmh
Stock Number:
043321-MU
Citation ID:
RRID:MMRRC_043321-MU
Other Names:
R5688 (G1)
Major Collection:

Gene Information

Ednrb
Name: endothelin receptor type B
Synonyms: ETb, Sox10m1, ETR-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13618
VEGA: 14
HGNC: HGNC:3180
Homologene: 89
Evl
Name: Ena-vasodilator stimulated phosphoprotein
Synonyms: b2b2600Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 14026
VEGA: 12
Homologene: 56752
Tert
Name: telomerase reverse transcriptase
Synonyms: TR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 21752
VEGA: 13
Homologene: 31141
Cpe
Name: carboxypeptidase E
Synonyms: CPH, carboxypeptidase H, Cph1, Cph-1, NF-alpha1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12876
HGNC: HGNC:2303
Homologene: 48052
Pcf11
Name: PCF11 cleavage and polyadenylation factor subunit
Synonyms: 5730417B17Rik, 2500001H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74737
Homologene: 32282
Slk
Name: STE20-like kinase
Synonyms: 9A2, mSLK, Etk4, SLK, Stk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20874
Homologene: 22515
Thada
Name: thyroid adenoma associated
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240174
VEGA: 17
Homologene: 75175
Anp32b
Name: acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
Synonyms: PHAPI2a, PAL31, 2410015B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67628
Homologene: 137872
Hars
Name: histidyl-tRNA synthetase
Synonyms: MMHRS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 15115
VEGA: 18
HGNC: HGNC:4816
Homologene: 1592
Faf1
Name: Fas-associated factor 1
Synonyms: Fam, Dffrx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14084
HGNC: HGNC:3578
Homologene: 5120
Mtrex
Name: Mtr4 exosome RNA helicase
Synonyms: 2610528A15Rik, Skiv2l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72198
VEGA: 13
Homologene: 6257
Dcp1b
Name: decapping mRNA 1B
Synonyms: B930050E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 319618
Homologene: 51881
Pyroxd1
Name: pyridine nucleotide-disulphide oxidoreductase domain 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232491
Homologene: 11758
Calcr
Name: calcitonin receptor
Synonyms: Clr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12311
HGNC: HGNC:1440
Homologene: 1320
Plxnb2
Name: plexin B2
Synonyms: Debt, 1110007H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 140570
HGNC: HGNC:9104
Homologene: 66630
Alms1
Name: ALMS1, centrosome and basal body associated
Synonyms: Alstrom syndrome 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 236266
HGNC: HGNC:428
Homologene: 49406
Atf7
Name: activating transcription factor 7
Synonyms: C130020M04Rik, 1110012F10Rik, 9430065F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223922
HGNC: HGNC:792
Homologene: 4994
Lca5
Name: Leber congenital amaurosis 5 (human)
Synonyms: 5730406O13Rik, ORF64, 4930431B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 75782
Homologene: 32718
H1f2
Name: H1.2 linker histone, cluster member
Synonyms: H1c, H1var1, H1.2, H1f2, 0610008C09Rik, Hist1h1c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 50708
HGNC: HGNC:4716
Homologene: 68455
Cemip
Name: cell migration inducing protein, hyaluronan binding
Synonyms: 12H19.01.T7, 6330404C01Rik, 9930013L23Rik, Hybid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 80982
Homologene: 10268
Ubqln4
Name: ubiquilin 4
Synonyms: UBIN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 94232
HGNC: HGNC:1237
Homologene: 41346
Slc35f5
Name: solute carrier family 35, member F5
Synonyms: 1300003P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74150
Homologene: 5745
Cep295
Name: centrosomal protein 295
Synonyms: LOC382128, 5830418K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319675
Homologene: 27936
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, 2900022L05Rik, Dnhd3, Dnahc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Garre1
Name: granule associated Rac and RHOG effector 1
Synonyms: 4931406P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233103
Homologene: 8795
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Cyp2j11
Name: cytochrome P450, family 2, subfamily j, polypeptide 11
Synonyms: Cyp2j11-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100066
Homologene: 133819
Rnasel
Name: ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
Synonyms: 2-5A-dependent RNAase, E230029I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 24014
Homologene: 8040
Plcb1
Name: phospholipase C, beta 1
Synonyms: 3110043I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18795
Homologene: 22876
Rhobtb3
Name: Rho-related BTB domain containing 3
Synonyms: 1700040C17Rik, 4930503C18Rik, 2610033K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 73296
Homologene: 8932
Atp10b
Name: ATPase, class V, type 10B
Synonyms: 5930426O13Rik, 9030605H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 319767
Homologene: 70969
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: DY6, 2310047C17Rik, 1110004P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Oas3
Name: 2'-5' oligoadenylate synthetase 3
Synonyms: 2'-5' oligoadenylate synthetase-like 10, Oasl10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 246727
HGNC: HGNC:8088
Homologene: 4510
Zfp947
Name: zinc finger protein 947
Synonyms: Gm4769
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 210853
Homologene: 133253
Shank1
Name: SH3 and multiple ankyrin repeat domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243961
Homologene: 22949
Defb7
Name: defensin beta 7
Synonyms: mBD7, Defb15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 246080
Cd248
Name: CD248 antigen, endosialin
Synonyms: 2610111G01Rik, Tem1, Cd164l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 70445
VEGA: 19
Homologene: 10699
Slc29a4
Name: solute carrier family 29 (nucleoside transporters), member 4
Synonyms: ENT4, mPMAT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243328
Homologene: 71345
Engase
Name: endo-beta-N-acetylglucosaminidase
Synonyms: D230014K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217364
Homologene: 13666
Cacna2d1
Name: calcium channel, voltage-dependent, alpha2/delta subunit 1
Synonyms: Cchl2a, Cacna2, Ca(v)alpha2delta1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12293
HGNC: HGNC:1399
Homologene: 579
Acp7
Name: acid phosphatase 7, tartrate resistant
Synonyms: C330005M16Rik, Papl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101744
Homologene: 23924
Lrit1
Name: leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
Synonyms: Lrrc21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239037
Homologene: 9215
Unc45b
Name: unc-45 myosin chaperone B
Synonyms: UNC45, D230041A13Rik, Cmya4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217012
Homologene: 14666
Olfr1155
Name: olfactory receptor 1155
Synonyms: GA_x6K02T2Q125-49426894-49425950, MOR174-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258636
Homologene: 133739
Cntn5
Name: contactin 5
Synonyms: LOC244683, NB-2, A830025P08Rik, 6720426O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244682
HGNC: HGNC:2175
Homologene: 28447
Slc28a3
Name: solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
Synonyms: Cnt3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 114304
Homologene: 32533
Aldh1l2
Name: aldehyde dehydrogenase 1 family, member L2
Synonyms: D330038I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216188
Homologene: 51942
Mgst1
Name: microsomal glutathione S-transferase 1
Synonyms: 1500002K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 56615
HGNC: HGNC:7061
Homologene: 10544
Vmn2r65
Name: vomeronasal 2, receptor 65
Synonyms: ENSMUSG00000070600
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100009609
Slco6d1
Name: solute carrier organic anion transporter family, member 6d1
Synonyms: 4921511I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70866
Homologene: 86643
Olfr145
Name: olfactory receptor 145
Synonyms: MOR161-6, GA_x6K02T2PVTD-31578734-31579666, K21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258310
HGNC: HGNC:8477
Homologene: 56568
Ovch2
Name: ovochymase 2
Synonyms: 9230106D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244199
Homologene: 18255
Lmtk3
Name: lemur tyrosine kinase 3
Synonyms: Aatyk3, AATYK3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381983
Homologene: 79449
Zfp964
Name: zinc finger protein 964
Synonyms: Gm7187
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 636741
Homologene: 130114
Hagh
Name: hydroxyacyl glutathione hydrolase
Synonyms: Rsp29, Glo-2, Glo2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14651
HGNC: HGNC:4805
Homologene: 3890
Map4k2
Name: mitogen-activated protein kinase kinase kinase kinase 2
Synonyms: BL44, Rab8ip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 26412
HGNC: HGNC:6864
Homologene: 3370
Olfr1204
Name: olfactory receptor 1204
Synonyms: GA_x6K02T2Q125-50322618-50323547, MOR232-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258455
Homologene: 133021
Sh3bp5
Name: SH3-domain binding protein 5 (BTK-associated)
Synonyms: Sab
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 24056
Homologene: 23450
Gm5460
Name: predicted gene 5460
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 432838
VEGA: 14
Spata31d1d
Name: spermatogenesis associated 31 subfamily D, member 1D
Synonyms: 4932411G14Rik, Fam75d1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238663
Homologene: 129932
Gm7356
Name: predicted gene 7356
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 664821
Homologene: 133217
Inadl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 98,480,768 bp
  • C to T, chromosome 1 at 125,591,038 bp
  • G to A, chromosome 1 at 153,753,706 bp
  • C to T, chromosome 2 at 52,196,327 bp
  • T to C, chromosome 2 at 76,734,128 bp
  • T to A, chromosome 2 at 76,879,984 bp
  • T to A, chromosome 2 at 87,943,208 bp
  • C to T, chromosome 2 at 88,852,679 bp
  • A to T, chromosome 2 at 135,335,480 bp
  • T to C, chromosome 3 at 88,565,268 bp
  • T to A, chromosome 4 at 46,469,868 bp
  • G to A, chromosome 4 at 96,345,121 bp
  • A to T, chromosome 4 at 98,520,810 bp
  • C to A, chromosome 4 at 109,794,813 bp
  • A to T, chromosome 5 at 16,358,952 bp
  • T to C, chromosome 5 at 120,758,802 bp
  • T to C, chromosome 5 at 142,714,098 bp
  • T to A, chromosome 6 at 3,714,730 bp
  • T to A, chromosome 6 at 85,599,895 bp
  • T to C, chromosome 6 at 119,217,911 bp
  • T to C, chromosome 6 at 138,141,800 bp
  • C to A, chromosome 6 at 142,353,540 bp
  • G to A, chromosome 7 at 28,616,495 bp
  • T to A, chromosome 7 at 34,253,991 bp
  • T to G, chromosome 7 at 34,284,709 bp
  • A to T, chromosome 7 at 44,354,487 bp
  • T to C, chromosome 7 at 45,791,410 bp
  • C to T, chromosome 7 at 83,961,641 bp
  • T to C, chromosome 7 at 84,940,692 bp
  • T to A, chromosome 7 at 92,658,808 bp
  • A to G, chromosome 7 at 107,793,994 bp
  • T to G, chromosome 8 at 19,495,151 bp
  • T to C, chromosome 8 at 64,609,155 bp
  • T to A, chromosome 8 at 69,664,116 bp
  • A to G, chromosome 9 at 9,748,422 bp
  • G to T, chromosome 9 at 15,331,986 bp
  • A to C, chromosome 9 at 37,898,063 bp
  • C to A, chromosome 9 at 83,398,566 bp
  • A to T, chromosome 10 at 83,501,925 bp
  • A to T, chromosome 11 at 43,201,173 bp
  • C to T, chromosome 11 at 69,458,920 bp
  • A to T, chromosome 11 at 82,922,817 bp
  • A to C, chromosome 11 at 118,487,320 bp
  • G to A, chromosome 12 at 108,673,353 bp
  • A to G, chromosome 13 at 23,739,165 bp
  • A to T, chromosome 13 at 58,558,649 bp
  • G to T, chromosome 13 at 59,726,508 bp
  • G to A, chromosome 13 at 73,639,156 bp
  • G to T, chromosome 13 at 75,872,418 bp
  • A to T, chromosome 13 at 112,873,056 bp
  • C to A, chromosome 14 at 31,377,495 bp
  • C to A, chromosome 14 at 34,045,795 bp
  • C to T, chromosome 14 at 37,062,428 bp
  • T to C, chromosome 14 at 103,823,395 bp
  • T to C, chromosome 15 at 89,158,696 bp
  • C to T, chromosome 15 at 102,551,509 bp
  • T to A, chromosome 17 at 14,000,607 bp
  • T to A, chromosome 17 at 22,146,085 bp
  • T to C, chromosome 17 at 24,850,594 bp
  • T to C, chromosome 17 at 84,451,727 bp
  • A to T, chromosome 18 at 36,772,316 bp
  • A to G, chromosome 19 at 5,069,935 bp
  • C to A, chromosome 19 at 6,346,806 bp
  • A to G, chromosome 19 at 9,002,519 bp
  • A to G, chromosome 19 at 47,620,012 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5688 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043321-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.