Strain Name:
C57BL/6J-MtgxR5699Btlr
Stock Number:
043327-MU
Citation ID:
RRID:MMRRC_043327-MU
Other Names:
R5699 (G1)
Major Collection:

Gene Information

Cdh11
Name: cadherin 11
Synonyms: osteoblast-cadherin, OB-cadherin, Cad11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12552
HGNC: HGNC:1750
Homologene: 1361
Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: F4/80, DD7A5-7, TM7LN3, EGF-TM7, Ly71, Emr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Rc3h1
Name: RING CCCH (C3H) domains 1
Synonyms: roquin, 5730557L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381305
Homologene: 19036
Slco1a5
Name: solute carrier organic anion transporter family, member 1a5
Synonyms: Oatp3, Slc21a7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 108096
Homologene: 56603
Scn3a
Name: sodium channel, voltage-gated, type III, alpha
Synonyms: LOC381367, Nav1.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20269
Homologene: 56005
Slit1
Name: slit guidance ligand 1
Synonyms: Slil1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20562
Homologene: 2302
Usp47
Name: ubiquitin specific peptidase 47
Synonyms: 4930502N04Rik, A630020C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74996
Homologene: 9929
Eml4
Name: echinoderm microtubule associated protein like 4
Synonyms: 4930443C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 78798
VEGA: 17
HGNC: HGNC:1316
Homologene: 56841
Fancc
Name: Fanconi anemia, complementation group C
Synonyms: Facc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14088
HGNC: HGNC:3584
Homologene: 109
Cyp51
Name: cytochrome P450, family 51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13121
HGNC: HGNC:2649
Homologene: 55488
Pgr
Name: progesterone receptor
Synonyms: NR3C3, PR, 9930019P03Rik, PR-B, PR-A, ENSMUSG00000074510
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18667
HGNC: HGNC:8910
Homologene: 713
Slit2
Name: slit guidance ligand 2
Synonyms: Slil3, Drad-1, E130320P19Rik, E030015M03Rik, b2b1200.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20563
Homologene: 3516
Adam11
Name: a disintegrin and metallopeptidase domain 11
Synonyms: Mdc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11488
HGNC: HGNC:189
Homologene: 7614
Snrnp40
Name: small nuclear ribonucleoprotein 40 (U5)
Synonyms: 0610009C03Rik, Wdr57
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66585
Homologene: 3538
Pdp1
Name: pyruvate dehydrogenase phosphatase catalytic subunit 1
Synonyms: LOC381511, Ppm2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381511
HGNC: HGNC:9279
Homologene: 31928
Lgr6
Name: leucine-rich repeat-containing G protein-coupled receptor 6
Synonyms: A530037C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329252
Homologene: 49680
Clk1
Name: CDC-like kinase 1
Synonyms: STY, Clk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12747
HGNC: HGNC:2068
Homologene: 101535
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Tubgcp2
Name: tubulin, gamma complex associated protein 2
Synonyms: 1700022B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74237
Homologene: 55980
Tbc1d2
Name: TBC1 domain family, member 2
Synonyms: LOC381605, PARIS-1, PARIS1, A630005A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381605
Homologene: 10190
BC055324
Name: cDNA sequence BC055324
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381306
Homologene: 10058
Trhde
Name: TRH-degrading enzyme
Synonyms: 9330155P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237553
Homologene: 75007
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, D830007G01Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Nwd1
Name: NACHT and WD repeat domain containing 1
Synonyms: A230063L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 319555
Homologene: 72261
Eps8l3
Name: EPS8-like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99662
Homologene: 15878
Slc22a30
Name: solute carrier family 22, member 30
Synonyms: C730048C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 319800
Homologene: 77136
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 435626
Homologene: 52359
Lmbrd2
Name: LMBR1 domain containing 2
Synonyms: 9930036E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 320506
VEGA: 15
Homologene: 44696
4930486L24Rik
Name: RIKEN cDNA 4930486L24 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 214639
VEGA: 13
HGNC: HGNC:2537
Homologene: 138410
Cdh2
Name: cadherin 2
Synonyms: N-cadherin, Ncad, N-CAD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 12558
HGNC: HGNC:1759
Homologene: 20424
Grid2
Name: glutamate receptor, ionotropic, delta 2
Synonyms: GluRdelta2, tpr, B230104L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14804
HGNC: HGNC:4576
Homologene: 74399
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
Or5b118
Name: olfactory receptor family 5 subfamily B member 118
Synonyms: GA_x6K02T2RE5P-3803583-3804527, MOR202-26P, MOR202-42, Olfr1474
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258123
Homologene: 79417
Kyat1
Name: kynurenine aminotransferase 1
Synonyms: cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase), 2010009K05Rik, KATI, Kat1, Ccbl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70266
HGNC: HGNC:1564
Homologene: 37872
Myod1
Name: myogenic differentiation 1
Synonyms: MYF3, MyoD, Myod-1, bHLHc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17927
HGNC: HGNC:7611
Homologene: 7857
Ano2
Name: anoctamin 2
Synonyms: Tmem16b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243634
HGNC: HGNC:1183
Homologene: 23221
Cpt1b
Name: carnitine palmitoyltransferase 1b, muscle
Synonyms: M-CPTI, M-CPT I, Cpt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12895
HGNC: HGNC:2329
Homologene: 22548
Rsbn1
Name: rosbin, round spermatid basic protein 1
Synonyms: Rsbp, C230004D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229675
Homologene: 10154
Vmn1r201
Name: vomeronasal 1 receptor 201
Synonyms: V1ri4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171255
Homologene: 110880
Car13
Name: carbonic anhydrase 13
Synonyms: 2310075C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71934
Homologene: 75207
Rbbp8nl
Name: RBBP8 N-terminal like
Synonyms: BC066135
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 271887
Homologene: 76811
Ikbke
Name: inhibitor of kappaB kinase epsilon
Synonyms: IKK-i, IKKepsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 56489
Homologene: 23168
C2cd4c
Name: C2 calcium-dependent domain containing 4C
Synonyms: LOC237397, 4932409I22Rik, Fam148c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237397
VEGA: 10
Homologene: 19012
Zbtb49
Name: zinc finger and BTB domain containing 49
Synonyms: 4930518A03Rik, Zfp509
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75079
Homologene: 34825
1700128F08Rik
Name: RIKEN cDNA 1700128F08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 76669
VEGA: 9
Cd38
Name: CD38 antigen
Synonyms: Cd38-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12494
HGNC: HGNC:1667
Homologene: 1345
Zeb2
Name: zinc finger E-box binding homeobox 2
Synonyms: SIP1, Zfx1b, 9130203F04Rik, D130016B08Rik, Zfhx1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 24136
Homologene: 8868
Tll1
Name: tolloid-like
Synonyms: Tll-1, b2b2476Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 21892
Homologene: 49202
Xkr8
Name: X-linked Kx blood group related 8
Synonyms: LOC381560, 4931440N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381560
Homologene: 23068
Mlx
Name: MAX-like protein X
Synonyms: BigMax alpha, Tcfl4, bHLHd13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21428
Homologene: 7969
Dnali1
Name: dynein, axonemal, light intermediate polypeptide 1
Synonyms: 1700023A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75563
Homologene: 2586
Rfpl4b
Name: ret finger protein-like 4B
Synonyms: LOC215919, Gm62, Gm3037
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215919
Homologene: 130122
Disp1
Name: dispatched RND transporter family member 1
Synonyms: DispA, 1190008H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68897
Homologene: 14133
Adh7
Name: alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
Synonyms: IV ADH, Adh-3, Adh-3t, Adt-1, Adh3-t, Adh3-e, Adh3, Adh4, Adh-3e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11529
HGNC: HGNC:256
Homologene: 37333
Pacsin3
Name: protein kinase C and casein kinase substrate in neurons 3
Synonyms: 4921507A02Rik, 6330413E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 80708
HGNC: HGNC:8572
Homologene: 41117
Or6c3
Name: olfactory receptor family 6 subfamily C member 3
Synonyms: GA_x6K02T2PULF-11151514-11152449, MOR111-4, Olfr788
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258544
Homologene: 74200
Ubap1l
Name: ubiquitin-associated protein 1-like
Synonyms: LOC208080, Gm514
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208080
VEGA: 9
Homologene: 19477
Prrt2
Name: proline-rich transmembrane protein 2
Synonyms: 1500031I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69017
Homologene: 114328
Pcdhgb5
Name: protocadherin gamma subfamily B, 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93702
HGNC: HGNC:8712
Homologene: 55773
Lrrc26
Name: leucine rich repeat containing 26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227618
Homologene: 16228
Stk16
Name: serine/threonine kinase 16
Synonyms: Embryo-Derived Protein Kinase, EDPK, Krct, PKL12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20872
Homologene: 2739
Or56b2j
Name: olfactory receptor family 56 subfamily B member 2J
Synonyms: GA_x6K02T2PBJ9-7331927-7332961, MOR40-12, Olfr663
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 257914
Homologene: 133594
4931431F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 58,420,195 bp
  • T to C, chromosome 1 at 74,147,663 bp
  • T to A, chromosome 1 at 75,213,604 bp
  • C to T, chromosome 1 at 131,276,467 bp
  • C to T, chromosome 1 at 134,994,010 bp
  • G to T, chromosome 1 at 160,930,253 bp
  • A to T, chromosome 1 at 163,957,551 bp
  • TTGA to T, chromosome 1 at 183,088,555 bp
  • T to A, chromosome 2 at 25,290,524 bp
  • G to A, chromosome 2 at 27,997,599 bp
  • G to A, chromosome 2 at 30,186,650 bp
  • T to A, chromosome 2 at 44,997,788 bp
  • T to C, chromosome 2 at 65,507,264 bp
  • T to C, chromosome 2 at 76,711,537 bp
  • A to T, chromosome 2 at 91,262,781 bp
  • T to C, chromosome 2 at 180,278,668 bp
  • A to G, chromosome 3 at 14,650,689 bp
  • T to C, chromosome 3 at 103,962,485 bp
  • C to A, chromosome 3 at 107,879,579 bp
  • G to A, chromosome 3 at 138,226,326 bp
  • T to C, chromosome 4 at 11,960,907 bp
  • T to C, chromosome 4 at 46,616,298 bp
  • C to T, chromosome 4 at 125,059,050 bp
  • G to T, chromosome 4 at 130,365,165 bp
  • C to T, chromosome 4 at 132,728,057 bp
  • A to G, chromosome 5 at 4,101,213 bp
  • A to T, chromosome 5 at 38,216,526 bp
  • A to G, chromosome 5 at 43,900,386 bp
  • G to A, chromosome 5 at 48,220,991 bp
  • G to A, chromosome 6 at 63,908,991 bp
  • A to G, chromosome 6 at 125,872,740 bp
  • C to A, chromosome 6 at 142,248,816 bp
  • A to G, chromosome 7 at 46,376,983 bp
  • A to G, chromosome 7 at 104,129,425 bp
  • T to G, chromosome 7 at 104,703,993 bp
  • A to G, chromosome 7 at 112,109,997 bp
  • T to A, chromosome 7 at 127,018,727 bp
  • A to T, chromosome 7 at 139,998,788 bp
  • T to A, chromosome 8 at 64,117,940 bp
  • G to A, chromosome 8 at 72,702,974 bp
  • A to G, chromosome 8 at 102,634,543 bp
  • A to G, chromosome 9 at 8,225,319 bp
  • C to T, chromosome 9 at 8,900,599 bp
  • T to A, chromosome 9 at 65,372,055 bp
  • T to A, chromosome 10 at 38,821,285 bp
  • A to G, chromosome 10 at 79,612,551 bp
  • A to T, chromosome 10 at 114,588,502 bp
  • A to C, chromosome 10 at 129,472,877 bp
  • A to G, chromosome 11 at 101,088,694 bp
  • A to T, chromosome 11 at 102,773,640 bp
  • T to A, chromosome 13 at 22,475,239 bp
  • A to G, chromosome 13 at 60,853,596 bp
  • A to T, chromosome 13 at 63,330,632 bp
  • G to T, chromosome 15 at 9,175,182 bp
  • T to A, chromosome 15 at 89,424,273 bp
  • T to C, chromosome 17 at 30,810,324 bp
  • C to T, chromosome 17 at 57,481,007 bp
  • T to G, chromosome 17 at 83,410,085 bp
  • G to A, chromosome 18 at 16,646,522 bp
  • T to A, chromosome 18 at 37,731,917 bp
  • G to A, chromosome 19 at 8,344,393 bp
  • A to G, chromosome 19 at 13,470,972 bp
  • A to G, chromosome 19 at 41,625,520 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5699 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043327-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.