Strain Name:
C57BL/6J-MtgxR5700Btlr
Stock Number:
043328-MU
Citation ID:
RRID:MMRRC_043328-MU
Other Names:
R5700 (G1)
Major Collection:

Gene Information

Hgf
Name: hepatocyte growth factor
Synonyms: NK1, NK2, HGF/SF, C230052L06Rik, scatter factor, SF/HGF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 15234
HGNC: HGNC:4893
Homologene: 503
Thbs4
Name: thrombospondin 4
Synonyms: TSP4, TSP-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 21828
Homologene: 20691
Spns1
Name: spinster homolog 1
Synonyms: 2210013K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 73658
Homologene: 41530
Plcd3
Name: phospholipase C, delta 3
Synonyms: 2610205J15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72469
HGNC: HGNC:9061
Homologene: 14858
Kdm4b
Name: lysine (K)-specific demethylase 4B
Synonyms: Jmjd2b, 4732474L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 193796
Homologene: 27773
Zfhx3
Name: zinc finger homeobox 3
Synonyms: WBP9, Sci, A230102L03Rik, Atbf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Armc8
Name: armadillo repeat containing 8
Synonyms: HSPC056, Gid5, 1200015K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74125
Homologene: 9121
Casr
Name: calcium-sensing receptor
Synonyms: CaR, cation sensing receptor, Gprc2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12374
HGNC: HGNC:1514
Homologene: 332
Acadvl
Name: acyl-Coenzyme A dehydrogenase, very long chain
Synonyms: VLCAD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11370
HGNC: HGNC:92
Homologene: 5
Btla
Name: B and T lymphocyte associated
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 208154
Homologene: 52233
Scmh1
Name: sex comb on midleg homolog 1
Synonyms: Scml3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 29871
Homologene: 32146
Zcchc7
Name: zinc finger, CCHC domain containing 7
Synonyms: 4930572I07Rik, D4Wsu132e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 319885
Homologene: 22217
Barx2
Name: BarH-like homeobox 2
Synonyms: 2310006E12Rik, Barx2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12023
HGNC: HGNC:956
Homologene: 2715
Klhl6
Name: kelch-like 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 239743
Homologene: 15603
Klhl1
Name: kelch-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 93688
HGNC: HGNC:6352
Homologene: 56903
Gm4884
Name: predicted gene 4884
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233164
Ccser1
Name: coiled-coil serine rich 1
Synonyms: Fam190a, 6230405M12Rik, C130092O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232035
Homologene: 28086
Dbt
Name: dihydrolipoamide branched chain transacylase E2
Synonyms: D3Wsu60e, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase, dihydrolipoyl transacylase, BCKAD E2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 13171
HGNC: HGNC:2698
Homologene: 1444
Pqlc2
Name: PQ loop repeat containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 212555
Homologene: 56784
Trim34b
Name: tripartite motif-containing 34B
Synonyms: Gm15134, Trim34-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434218
Homologene: 128238
Nckap5
Name: NCK-associated protein 5
Synonyms: E030049G20Rik, D130011D22Rik, LOC380609
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 210356
Homologene: 35542
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380698
Homologene: 70869
Ppp2r1b
Name: protein phosphatase 2, regulatory subunit A, beta
Synonyms: 2410091N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 73699
HGNC: HGNC:9303
Homologene: 70244
Olfr716
Name: olfactory receptor 716
Synonyms: MOR260-2, GA_x6K02T2PBJ9-9497411-9498355
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258597
Homologene: 121514
Grid2
Name: glutamate receptor, ionotropic, delta 2
Synonyms: GluRdelta2, B230104L07Rik, tpr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14804
HGNC: HGNC:4576
Homologene: 74399
Parp6
Name: poly (ADP-ribose) polymerase family, member 6
Synonyms: 3110038K10Rik, 2310028P13Rik, 1700119G14Rik, C030013N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 67287
VEGA: 9
Homologene: 10627
Abcc2
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Synonyms: Mrp2, Cmoat, multidrug resistance protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 12780
HGNC: HGNC:53
Homologene: 68052
Serpinb6c
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6c
Synonyms: Spi3C, ovalbumin, SPIC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 97848
HGNC: HGNC:8950
Hs6st3
Name: heparan sulfate 6-O-sulfotransferase 3
Synonyms: 6OST3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 50787
VEGA: 14
Homologene: 89201
Fdps
Name: farnesyl diphosphate synthetase
Synonyms: 6030492I17Rik, Fdpsl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 110196
HGNC: HGNC:3631
Homologene: 1519
Vmn1r72
Name: vomeronasal 1 receptor 72
Synonyms: V1rg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 252905
Homologene: 74318
Hoxc9
Name: homeobox C9
Synonyms: Hox-3.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 15427
HGNC: HGNC:5130
Homologene: 130558
Best1
Name: bestrophin 1
Synonyms: mBest1, best macular dystrophy, Vmd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 24115
Homologene: 37895
Cr2
Name: complement receptor 2
Synonyms: Cr1, CD21, Cr-1, CD35, Cr-2, C3DR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12902
HGNC: HGNC:2336
Homologene: 55611
Timm44
Name: translocase of inner mitochondrial membrane 44
Synonyms: Tim44, D8Ertd118e, 0710005E20Rik, Mimt44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 21856
Homologene: 4631
Olfr193
Name: olfactory receptor 193
Synonyms: GA_x54KRFPKG5P-55338697-55337768, MOR113-7P, MOR113-7P, MOR183-7P, Olfr1540-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 257972
Homologene: 128162
Rftn1
Name: raftlin lipid raft linker 1
Synonyms: 2310015N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 76438
Homologene: 18745
Ston1
Name: stonin 1
Synonyms: 4921524J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 77057
Homologene: 122152
Olfr1369-ps1
Name: olfactory receptor 1369, pseudogene 1
Synonyms: MOR256-31, GA_x6K02T2QHY8-12126170-12125935
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 404504
HGNC: HGNC:8281
Gm5592
Name: predicted gene 5592
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434172
Homologene: 45597
Zfand1
Name: zinc finger, AN1-type domain 1
Synonyms: 2310008M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66361
Homologene: 6779
Mptx2
Name: mucosal pentraxin 2
Synonyms: Gm11062
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 100504232
Homologene: 134535
Medag
Name: mesenteric estrogen dependent adipogenesis
Synonyms: MEDA-4, 6330406I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70717
Homologene: 12364
Gm7367
Name: predicted pseudogene 7367
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 664849
Olfr8
Name: olfactory receptor 8
Synonyms: MOR139-5P, GA_x6K02T2QGN0-2857086-2856154
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 18372
Homologene: 136441
Btbd8
Name: BTB (POZ) domain containing 8
Synonyms: Gm16115, EG627196
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100503185
VEGA: 5
Homologene: 82388
Fam53b
Name: family with sequence similarity 53, member B
Synonyms: A930008G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 77938
Homologene: 8776
Csl
Name: citrate synthase like
Synonyms: 1700007H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71832
VEGA: 10
Homologene: 7131
Plscr5
Name: phospholipid scramblase family, member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 100504689
Homologene: 28688
Prnd
Name: prion like protein doppel
Synonyms: PrPLP, doppel, Dpl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 26434
Homologene: 8236
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 125,976,925 bp
  • G to A, chromosome 1 at 173,274,847 bp
  • A to G, chromosome 1 at 195,159,757 bp
  • G to A, chromosome 2 at 131,953,343 bp
  • T to A, chromosome 3 at 10,341,019 bp
  • T to C, chromosome 3 at 89,095,649 bp
  • G to A, chromosome 3 at 116,520,303 bp
  • T to C, chromosome 4 at 44,931,084 bp
  • T to C, chromosome 4 at 120,516,946 bp
  • C to T, chromosome 4 at 139,300,254 bp
  • C to T, chromosome 5 at 16,610,124 bp
  • T to C, chromosome 5 at 107,503,648 bp
  • T to C, chromosome 5 at 149,422,217 bp
  • C to A, chromosome 6 at 61,311,276 bp
  • T to A, chromosome 6 at 64,094,432 bp
  • C to T, chromosome 7 at 11,670,423 bp
  • A to G, chromosome 7 at 41,043,219 bp
  • A to G, chromosome 7 at 41,158,579 bp
  • A to T, chromosome 7 at 60,155,762 bp
  • G to T, chromosome 7 at 104,336,411 bp
  • A to G, chromosome 7 at 107,147,541 bp
  • A to G, chromosome 7 at 126,372,469 bp
  • A to T, chromosome 7 at 132,760,020 bp
  • T to C, chromosome 8 at 4,274,171 bp
  • A to G, chromosome 8 at 108,933,867 bp
  • A to T, chromosome 9 at 31,858,765 bp
  • T to C, chromosome 9 at 50,878,157 bp
  • T to C, chromosome 9 at 59,624,727 bp
  • A to T, chromosome 9 at 92,205,511 bp
  • A to G, chromosome 9 at 99,496,149 bp
  • T to C, chromosome 10 at 78,955,484 bp
  • T to A, chromosome 10 at 99,759,015 bp
  • T to C, chromosome 11 at 59,133,194 bp
  • A to C, chromosome 11 at 70,013,203 bp
  • T to C, chromosome 11 at 103,073,763 bp
  • T to A, chromosome 13 at 21,116,001 bp
  • A to T, chromosome 13 at 33,899,308 bp
  • T to C, chromosome 13 at 92,776,953 bp
  • T to C, chromosome 14 at 96,518,040 bp
  • C to T, chromosome 14 at 119,138,787 bp
  • T to C, chromosome 15 at 102,981,881 bp
  • G to A, chromosome 16 at 19,957,218 bp
  • T to A, chromosome 16 at 36,509,617 bp
  • T to A, chromosome 16 at 45,250,573 bp
  • T to A, chromosome 16 at 59,109,993 bp
  • G to T, chromosome 17 at 50,002,669 bp
  • T to C, chromosome 17 at 56,351,700 bp
  • T to A, chromosome 17 at 88,644,339 bp
  • T to C, chromosome 19 at 9,997,199 bp
  • A to T, chromosome 19 at 43,798,194 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5700 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043328-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.