Strain Name:
C57BL/6J-MtgxR5748Btlr
Stock Number:
043355-MU
Citation ID:
RRID:MMRRC_043355-MU
Other Names:
R5748 (G1)
Major Collection:

Gene Information

Cntnap2
Name: contactin associated protein-like 2
Synonyms: 5430425M22Rik, Caspr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66797
Homologene: 69159
Upf1
Name: UPF1 regulator of nonsense transcripts homolog (yeast)
Synonyms: PNORF-1, B430202H16Rik, Rent1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 19704
HGNC: HGNC:9962
Homologene: 2185
Ylpm1
Name: YLP motif containing 1
Synonyms: Zap3, ZAP, A930013E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56531
Homologene: 87707
Zfp273
Name: zinc finger protein 273
Synonyms: 6820416H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 212569
Homologene: 133729
Med13l
Name: mediator complex subunit 13-like
Synonyms: 9030618F05Rik, Trap240L, 6330591G05Rik, 2210413I17Rik, Thrap2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 76199
Homologene: 25256
Gtse1
Name: G two S phase expressed protein 1
Synonyms: B99, Gtse-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 29870
VEGA: 15
Homologene: 8489
Anln
Name: anillin, actin binding protein
Synonyms: Scraps, 2900037I21Rik, 1110037A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68743
VEGA: 9
Homologene: 41281
Scaper
Name: S phase cyclin A-associated protein in the ER
Synonyms: D530014O03Rik, Zfp291
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244891
VEGA: 9
Homologene: 32488
Rsf1
Name: remodeling and spacing factor 1
Synonyms: C030033M12Rik, 4832420A03Rik, Hbxap, p325, XAP8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233532
Homologene: 41142
Sh3glb1
Name: SH3-domain GRB2-like B1 (endophilin)
Synonyms: Endophilin B1, Bif-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 54673
Homologene: 9337
Niban2
Name: niban apoptosis regulator 2
Synonyms: Fam129b, 9130404D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227737
Homologene: 11269
Ndufb6
Name: NADH:ubiquinone oxidoreductase subunit B6
Synonyms: LOC230075
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230075
HGNC: HGNC:7701
Homologene: 1864
Dhx16
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 16
Synonyms: Ddx16, 2410006N22Rik, DBP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 69192
HGNC: HGNC:2739
Homologene: 2658
Acy1
Name: aminoacylase 1
Synonyms: 1110014J22Rik, Acy-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 109652
HGNC: HGNC:177
Homologene: 110440
Iqgap3
Name: IQ motif containing GTPase activating protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 404710
Homologene: 26400
Nup85
Name: nucleoporin 85
Synonyms: frount, Pcnt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 445007
HGNC: HGNC:8734
Homologene: 11755
Mcm9
Name: minichromosome maintenance 9 homologous recombination repair factor
Synonyms: 9030408O17Rik, Mcmdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71567
VEGA: 10
Homologene: 13546
Lgr6
Name: leucine-rich repeat-containing G protein-coupled receptor 6
Synonyms: A530037C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329252
Homologene: 49680
Wdr6
Name: WD repeat domain 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83669
Homologene: 117682
Pot1a
Name: protection of telomeres 1A
Synonyms: 1500031H18Rik, Pot1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 101185
Homologene: 32263
Eml5
Name: echinoderm microtubule associated protein like 5
Synonyms: C130068M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319670
VEGA: 12
Homologene: 26807
Dlk1
Name: delta like non-canonical Notch ligand 1
Synonyms: SCP1, Peg9, pref-1, pG2, DlkI, ZOG, FA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13386
HGNC: HGNC:2907
Homologene: 2846
Invs
Name: inversin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16348
Homologene: 7786
Nrbp2
Name: nuclear receptor binding protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223649
VEGA: 15
Homologene: 135649
Rundc3a
Name: RUN domain containing 3A
Synonyms: Rap2ip, Rpip8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 51799
Homologene: 4871
Spata31
Name: spermatogenesis associated 31
Synonyms: Fam75a, 4930458L03Rik, Spata31a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 78124
Homologene: 84621
Scaf1
Name: SR-related CTD-associated factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233208
Olfr1251
Name: olfactory receptor 1251
Synonyms: MOR231-24_p, GA_x6K02T2Q125-51109312-51108356, MOR231-15P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259145
Homologene: 74065
Olfr720
Name: olfactory receptor 720
Synonyms: GA_x6K02T2PLTE-6544896-6543946, MOR274-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258387
Homologene: 74036
Olfr395
Name: olfactory receptor 395
Synonyms: GA_x6K02T2P1NL-4062605-4061667, MOR135-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259007
Stap2
Name: signal transducing adaptor family member 2
Synonyms: STAP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106766
VEGA: 17
Homologene: 9798
Olfr293
Name: olfactory receptor 293
Synonyms: MOR221-3, GA_x6K02T2NHDJ-9457744-9456734
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 257906
Homologene: 79385
Slc17a3
Name: solute carrier family 17 (sodium phosphate), member 3
Synonyms: Npt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105355
Homologene: 21319
C1qtnf4
Name: C1q and tumor necrosis factor related protein 4
Synonyms: 9430004J15Rik, 0710001E10Rik, CTRP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67445
Homologene: 12134
Gria1
Name: glutamate receptor, ionotropic, AMPA1 (alpha 1)
Synonyms: GluRA, 2900051M01Rik, GluA1, Glur-1, Glur1, HIPA1, Glr-1, Glr1, GluR1, GluR-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14799
HGNC: HGNC:4571
Homologene: 20226
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 435626
Homologene: 52359
Olfr1448
Name: olfactory receptor 1448
Synonyms: MOR202-5, GA_x6K02T2RE5P-3249780-3248836
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258696
Homologene: 64904
Mdga1
Name: MAM domain containing glycosylphosphatidylinositol anchor 1
Synonyms: 1200011I03Rik, Mamdc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74762
Homologene: 17780
Tmx3
Name: thioredoxin-related transmembrane protein 3
Synonyms: Txndc10, A730024F05Rik, 6430411B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67988
VEGA: 18
Homologene: 10381
Acan
Name: aggrecan
Synonyms: Cspg1, Agc1, b2b183Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11595
HGNC: HGNC:319
Homologene: 137204
Mcmdc2
Name: minichromosome maintenance domain containing 2
Synonyms: 6030422M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240697
Homologene: 18309
Stt3a
Name: STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
Synonyms: Itm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 16430
HGNC: HGNC:6172
Homologene: 40617
Slc41a2
Name: solute carrier family 41, member 2
Synonyms: A230035L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 338365
Homologene: 9870
Nacad
Name: NAC alpha domain containing
Synonyms: mKIAA0363
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192950
Homologene: 135717
Gm10549
Name: predicted gene 10549
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 433171
VEGA: 18
Cxcr6
Name: chemokine (C-X-C motif) receptor 6
Synonyms: STRL33, BONZO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 80901
VEGA: 9
Homologene: 38197
Hcn1
Name: hyperpolarization activated cyclic nucleotide gated potassium channel 1
Synonyms: hyperpolarization-activated, cyclic nucleotide-gated K+ 1, C630013B14Rik, HAC2, Bcng1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 15165
HGNC: HGNC:4845
Homologene: 32093
Mrgpra2b
Name: MAS-related GPR, member A2B
Synonyms: Mrgpra2, MrgA2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 235712
Homologene: 79615
Lrrc14b
Name: leucine rich repeat containing 14B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 432779
Homologene: 47758
Olfr1415
Name: olfactory receptor 1415
Synonyms: MOR103-12, GA_x6K02T2R7CC-81266841-81267776
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258228
Homologene: 79367
Slc10a5
Name: solute carrier family 10 (sodium/bile acid cotransporter family), member 5
Synonyms: LOC241877
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 241877
Homologene: 78106
Nkapl
Name: NFKB activating protein-like
Synonyms: 4921504I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66707
Homologene: 57034
Tcfl5
Name: transcription factor-like 5 (basic helix-loop-helix)
Synonyms: FIG beta, Figlb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 277353
Homologene: 4814
Polr2m
Name: polymerase (RNA) II (DNA directed) polypeptide M
Synonyms: Grinl1a, D9Wsu138e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 28015
Homologene: 9181
Popdc2
Name: popeye domain containing 2
Synonyms: Pop2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 64082
Homologene: 11147
Ebpl
Name: emopamil binding protein-like
Synonyms: 5730442K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68177
VEGA: 14
Homologene: 12243
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 9,911,807 bp
  • T to C, chromosome 1 at 74,147,663 bp
  • T to A, chromosome 1 at 92,491,093 bp
  • C to T, chromosome 1 at 134,994,010 bp
  • A to T, chromosome 2 at 32,919,569 bp
  • A to T, chromosome 2 at 89,667,802 bp
  • A to G, chromosome 2 at 90,889,533 bp
  • G to A, chromosome 2 at 180,642,257 bp
  • T to C, chromosome 3 at 10,335,331 bp
  • T to C, chromosome 3 at 88,109,370 bp
  • C to T, chromosome 3 at 144,712,649 bp
  • A to G, chromosome 4 at 40,279,234 bp
  • A to G, chromosome 4 at 48,307,823 bp
  • G to A, chromosome 5 at 118,593,445 bp
  • A to T, chromosome 6 at 25,758,856 bp
  • A to G, chromosome 6 at 45,715,884 bp
  • A to C, chromosome 7 at 45,012,806 bp
  • A to G, chromosome 7 at 47,502,532 bp
  • A to G, chromosome 7 at 79,089,699 bp
  • A to G, chromosome 7 at 86,664,085 bp
  • GCGGCGGC to GCGGCGGCGTCGGCGGC, chromosome 7 at 97,579,928 bp
  • A to G, chromosome 8 at 70,338,517 bp
  • T to C, chromosome 9 at 22,337,934 bp
  • A to T, chromosome 9 at 36,752,400 bp
  • T to C, chromosome 9 at 55,859,076 bp
  • C to T, chromosome 9 at 71,483,636 bp
  • T to A, chromosome 9 at 106,436,727 bp
  • T to C, chromosome 9 at 108,575,782 bp
  • C to T, chromosome 9 at 123,810,341 bp
  • A to T, chromosome 10 at 53,625,729 bp
  • C to A, chromosome 10 at 83,297,159 bp
  • T to A, chromosome 11 at 6,598,370 bp
  • A to G, chromosome 11 at 57,309,876 bp
  • A to G, chromosome 11 at 73,906,895 bp
  • G to A, chromosome 11 at 102,399,399 bp
  • T to A, chromosome 11 at 115,580,512 bp
  • T to A, chromosome 12 at 85,060,251 bp
  • T to A, chromosome 12 at 98,825,555 bp
  • T to C, chromosome 12 at 109,459,972 bp
  • A to G, chromosome 13 at 21,467,609 bp
  • T to A, chromosome 13 at 23,856,466 bp
  • A to G, chromosome 13 at 64,920,313 bp
  • T to C, chromosome 13 at 67,825,331 bp
  • T to A, chromosome 13 at 74,363,640 bp
  • A to T, chromosome 13 at 117,976,055 bp
  • T to C, chromosome 14 at 14,175,314 bp
  • A to T, chromosome 14 at 61,360,344 bp
  • T to C, chromosome 15 at 76,089,483 bp
  • T to C, chromosome 15 at 85,867,577 bp
  • A to T, chromosome 16 at 38,374,303 bp
  • C to T, chromosome 17 at 29,850,551 bp
  • T to C, chromosome 17 at 35,883,314 bp
  • C to T, chromosome 17 at 56,000,475 bp
  • C to A, chromosome 18 at 33,464,305 bp
  • T to C, chromosome 18 at 90,537,101 bp
  • T to A, chromosome 19 at 12,920,015 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5748 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043355-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.