Strain Name:
C57BL/6J-MtgxR5794Btlr
Stock Number:
043385-MU
Citation ID:
RRID:MMRRC_043385-MU
Other Names:
R5794 (G1)
Major Collection:

Gene Information

Ank2
Name: ankyrin 2, brain
Synonyms: Ankyrin-B, Ankyrin-2, Ank-2, ankyrin B, Gm4392
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Nfia
Name: nuclear factor I/A
Synonyms: NF1A, NF1-A, 1110047K16Rik, 9430022M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18027
HGNC: HGNC:7784
Homologene: 4086
Ece1
Name: endothelin converting enzyme 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230857
HGNC: HGNC:3146
Homologene: 1068
Clasrp
Name: CLK4-associating serine/arginine rich protein
Synonyms: Srsf16, SWAP2, Sfrs16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 53609
Homologene: 134306
Ano6
Name: anoctamin 6
Synonyms: 2900059G15Rik, F730003B03Rik, Tmem16f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105722
VEGA: 15
Homologene: 27888
Etl4
Name: enhancer trap locus 4
Synonyms: 9430077C05Rik, Skt, E330027G05Rik, Sickle tail, Etl-4, 6620402G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 208618
Homologene: 10477
Rabgap1
Name: RAB GTPase activating protein 1
Synonyms: Gapcena
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227800
Homologene: 49301
Psma3
Name: proteasome subunit alpha 3
Synonyms: Lmpc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19167
HGNC: HGNC:9532
Homologene: 2082
Rttn
Name: rotatin
Synonyms: C530033I08Rik, 4921538A15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 246102
VEGA: 18
Homologene: 65275
Smoc2
Name: SPARC related modular calcium binding 2
Synonyms: 1700056C05Rik, 5430426J21Rik, Smoc2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 64074
VEGA: 17
Homologene: 11150
Aftph
Name: aftiphilin
Synonyms: 9130023F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216549
Homologene: 9764
Gprc5c
Name: G protein-coupled receptor, family C, group 5, member C
Synonyms: 1110028I06Rik, 3200002M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70355
Homologene: 11099
Zfp592
Name: zinc finger protein 592
Synonyms: A730014M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233410
Homologene: 8759
Igf2r
Name: insulin-like growth factor 2 receptor
Synonyms: CI-MPR, CD222, IGF-II/CI-MPR, M6P/IGF2R, Mpr300, mannose-6-phosphate receptor, cation independent
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16004
HGNC: HGNC:5467
Homologene: 676
Psmd11
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Synonyms: 2610024G20Rik, 1810019E17Rik, C78232, 2810055C24Rik, S9, P44.5, 1700089D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69077
HGNC: HGNC:9556
Homologene: 2108
Kctd10
Name: potassium channel tetramerisation domain containing 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330171
Homologene: 32652
Tapt1
Name: transmembrane anterior posterior transformation 1
Synonyms: 4932414K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231225
Homologene: 80206
Vmn2r116
Name: vomeronasal 2, receptor 116
Synonyms: V2Rp5, EG619697
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 619697
Homologene: 86604
Cma1
Name: chymase 1, mast cell
Synonyms: Mcp5, Mcpt5, Mcp-5, MMCP-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 17228
VEGA: 14
HGNC: HGNC:2097
Homologene: 55606
Krt73
Name: keratin 73
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223915
Homologene: 27875
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75777
Homologene: 44907
Cep126
Name: centrosomal protein 126
Synonyms: AK129341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 234915
VEGA: 9
Homologene: 28313
Klk1b4
Name: kallikrein 1-related pepidase b4
Synonyms: Ngfa, mGk-4, Ngfa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18048
HGNC: HGNC:6364
Homologene: 68141
Serpine2
Name: serine (or cysteine) peptidase inhibitor, clade E, member 2
Synonyms: B230326M24Rik, PI7, nexin, PN-1, Spi4, protease nexin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20720
HGNC: HGNC:8951
Homologene: 21247
Kcnh3
Name: potassium voltage-gated channel, subfamily H (eag-related), member 3
Synonyms: Elk2, C030044P22Rik, Melk2, ether a go-go like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16512
VEGA: 15
HGNC: HGNC:6252
Homologene: 32150
Irgm1
Name: immunity-related GTPase family M member 1
Synonyms: Ifi1, Irgm, LRG-47, Iigp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15944
Homologene: 134089
Zfp827
Name: zinc finger protein 827
Synonyms: D630040G17Rik, 2810449M09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 622675
Homologene: 45622
Olfr996
Name: olfactory receptor 996
Synonyms: MOR175-4, GA_x6K02T2Q125-47058060-47059004
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258429
Homologene: 85934
Fbxw20
Name: F-box and WD-40 domain protein 20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 434440
Homologene: 110776
Hoxd9
Name: homeobox D9
Synonyms: Hox-5.2, Hox-4.4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 15438
HGNC: HGNC:5140
Homologene: 8409
Snai2
Name: snail family zinc finger 2
Synonyms: Snail2, Slugh, Slug
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20583
VEGA: 16
Homologene: 31127
Krt32
Name: keratin 32
Synonyms: Krt1-2, mHa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16670
HGNC: HGNC:6449
Homologene: 68246
Olfr788
Name: olfactory receptor 788
Synonyms: MOR111-4, GA_x6K02T2PULF-11151514-11152449
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258544
Homologene: 74200
Gnb2
Name: guanine nucleotide binding protein (G protein), beta 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14693
HGNC: HGNC:4398
Homologene: 68451
Napepld
Name: N-acyl phosphatidylethanolamine phospholipase D
Synonyms: NAPE-PLD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 242864
Homologene: 7094
Klrc1
Name: killer cell lectin-like receptor subfamily C, member 1
Synonyms: NKG2A, CD159a, NKG2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16641
HGNC: HGNC:6374
Homologene: 86848
Six4
Name: sine oculis-related homeobox 4
Synonyms: TrexBF, AREC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20474
Homologene: 69089
Prkrir
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Lrrc16a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 79,821,439 bp
  • T to A, chromosome 2 at 20,806,512 bp
  • T to A, chromosome 2 at 37,502,902 bp
  • T to A, chromosome 2 at 74,699,273 bp
  • T to C, chromosome 2 at 85,579,341 bp
  • T to C, chromosome 3 at 126,930,020 bp
  • G to T, chromosome 4 at 97,783,601 bp
  • A to G, chromosome 4 at 137,956,533 bp
  • T to A, chromosome 5 at 21,683,431 bp
  • C to T, chromosome 5 at 44,177,134 bp
  • G to A, chromosome 5 at 114,367,337 bp
  • T to C, chromosome 5 at 137,528,699 bp
  • C to T, chromosome 6 at 129,675,354 bp
  • A to T, chromosome 7 at 19,591,109 bp
  • A to T, chromosome 7 at 44,209,645 bp
  • G to T, chromosome 7 at 81,025,033 bp
  • T to A, chromosome 7 at 98,716,393 bp
  • T to C, chromosome 8 at 79,070,442 bp
  • T to G, chromosome 9 at 8,103,439 bp
  • T to C, chromosome 9 at 109,223,290 bp
  • A to T, chromosome 9 at 109,233,600 bp
  • A to C, chromosome 10 at 129,473,426 bp
  • T to C, chromosome 11 at 20,726,955 bp
  • T to C, chromosome 11 at 48,866,237 bp
  • T to A, chromosome 11 at 80,471,492 bp
  • C to A, chromosome 11 at 100,084,986 bp
  • G to T, chromosome 11 at 114,864,267 bp
  • A to G, chromosome 12 at 70,990,497 bp
  • A to T, chromosome 12 at 73,112,350 bp
  • G to T, chromosome 13 at 24,092,550 bp
  • T to C, chromosome 14 at 55,944,520 bp
  • G to T, chromosome 15 at 10,551,550 bp
  • A to T, chromosome 15 at 95,894,524 bp
  • A to C, chromosome 15 at 99,232,974 bp
  • T to A, chromosome 15 at 101,794,829 bp
  • A to T, chromosome 16 at 14,706,726 bp
  • T to C, chromosome 17 at 12,709,445 bp
  • T to A, chromosome 17 at 14,369,048 bp
  • T to C, chromosome 17 at 23,385,968 bp
  • G to T, chromosome 18 at 88,995,569 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5794 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043385-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.