Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR5794Btlr
Stock Number:
043385-MU
Citation ID:
RRID:MMRRC_043385-MU
Other Names:
R5794 (G1)
Major Collection:

Strain Information

Ank2
Name: ankyrin 2, brain
Synonyms: ankyrin B, Ank-2, Ankyrin-2, Ankyrin-B, Gm4392
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Nfia
Name: nuclear factor I/A
Synonyms: 1110047K16Rik, NF1-A, 9430022M17Rik, NF1A
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18027
HGNC: HGNC:7784
Homologene: 4086
Ece1
Name: endothelin converting enzyme 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230857
HGNC: HGNC:3146
Homologene: 1068
Clasrp
Name: CLK4-associating serine/arginine rich protein
Synonyms: SWAP2, Sfrs16, Srsf16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 53609
Homologene: 134306
Ano6
Name: anoctamin 6
Synonyms: 2900059G15Rik, F730003B03Rik, Tmem16f
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105722
VEGA: 15
Homologene: 27888
Etl4
Name: enhancer trap locus 4
Synonyms: Etl-4, E330027G05Rik, 6620402G01Rik, 9430077C05Rik, Skt, Sickle tail
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 208618
Homologene: 10477
Rabgap1
Name: RAB GTPase activating protein 1
Synonyms: Gapcena
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227800
Homologene: 49301
Psma3
Name: proteasome subunit alpha 3
Synonyms: Lmpc8
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 19167
HGNC: HGNC:9532
Homologene: 2082
Rttn
Name: rotatin
Synonyms: 4921538A15Rik, C530033I08Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 246102
VEGA: 18
Homologene: 65275
Smoc2
Name: SPARC related modular calcium binding 2
Synonyms: 1700056C05Rik, 5430426J21Rik, Smoc2l
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 64074
VEGA: 17
Homologene: 11150
Gprc5c
Name: G protein-coupled receptor, family C, group 5, member C
Synonyms: 1110028I06Rik, 3200002M13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70355
Homologene: 11099
Zfp592
Name: zinc finger protein 592
Synonyms: A730014M16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233410
Homologene: 8759
Igf2r
Name: insulin-like growth factor 2 receptor
Synonyms: Mpr300, CI-MPR, IGF-II/CI-MPR, M6P/IGF2R, CD222, mannose-6-phosphate receptor, cation independent
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16004
HGNC: HGNC:5467
Homologene: 676
Psmd11
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Synonyms: P44.5, S9, 1810019E17Rik, C78232, 2810055C24Rik, 2610024G20Rik, 1700089D09Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69077
HGNC: HGNC:9556
Homologene: 2108
Kctd10
Name: potassium channel tetramerisation domain containing 10
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330171
Homologene: 32652
Tapt1
Name: transmembrane anterior posterior transformation 1
Synonyms: 4932414K18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231225
Homologene: 80206
Vmn2r116
Name: vomeronasal 2, receptor 116
Synonyms: EG619697, V2Rp5
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 619697
Homologene: 86604
Cma1
Name: chymase 1, mast cell
Synonyms: MMCP-5, Mcp-5, Mcpt5, Mcp5
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 17228
VEGA: 14
HGNC: HGNC:2097
Homologene: 55606
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75777
Homologene: 44907
Cep126
Name: centrosomal protein 126
Synonyms: AK129341
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 234915
VEGA: 9
Homologene: 28313
Klk1b4
Name: kallikrein 1-related pepidase b4
Synonyms: mGk-4, Ngfa, Ngfa
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18048
Homologene: 68141
Serpine2
Name: serine (or cysteine) peptidase inhibitor, clade E, member 2
Synonyms: nexin, PN-1, PI7, protease nexin 1, Spi4, B230326M24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20720
HGNC: HGNC:8951
Homologene: 21247
Kcnh3
Name: potassium voltage-gated channel, subfamily H (eag-related), member 3
Synonyms: ether a go-go like, Elk2, Melk2, C030044P22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16512
VEGA: 15
HGNC: HGNC:6252
Homologene: 32150
Irgm1
Name: immunity-related GTPase family M member 1
Synonyms: LRG-47, Iigp3, Ifi1, Irgm
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15944
Homologene: 134089
Zfp827
Name: zinc finger protein 827
Synonyms: 2810449M09Rik, D630040G17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 622675
Homologene: 45622
Or5g27
Name: olfactory receptor family 5 subfamily G member 27
Synonyms: GA_x6K02T2Q125-47058060-47059004, MOR175-4, Olfr996
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258429
Homologene: 85934
Fbxw20
Name: F-box and WD-40 domain protein 20
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 434440
Homologene: 110776
Hoxd9
Name: homeobox D9
Synonyms: Hox-5.2, Hox-4.4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15438
HGNC: HGNC:5140
Homologene: 8409
Snai2
Name: snail family zinc finger 2
Synonyms: Slugh, Slug, Snail2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 20583
VEGA: 16
Homologene: 31127
Krt32
Name: keratin 32
Synonyms: mHa2, Krt1-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16670
HGNC: HGNC:6449
Homologene: 68246
Or6c3
Name: olfactory receptor family 6 subfamily C member 3
Synonyms: GA_x6K02T2PULF-11151514-11152449, MOR111-4, Olfr788
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258544
Homologene: 74200
Gnb2
Name: guanine nucleotide binding protein (G protein), beta 2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14693
HGNC: HGNC:4398
Homologene: 68451
Napepld
Name: N-acyl phosphatidylethanolamine phospholipase D
Synonyms: NAPE-PLD
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 242864
Homologene: 7094
Klrc1
Name: killer cell lectin-like receptor subfamily C, member 1
Synonyms: NKG2B, NKG2A, CD159a
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16641
Homologene: 86848
Six4
Name: sine oculis-related homeobox 4
Synonyms: AREC3, TrexBF
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20474
Homologene: 69089
Prkrir
Name:
Type: Gene
Species: Mouse
Chromosome: 7
Lrrc16a
Name:
Type: Gene
Species: Mouse
Chromosome: 13
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 79,821,439 bp
  • T to A, chromosome 2 at 20,806,512 bp
  • T to A, chromosome 2 at 37,502,902 bp
  • T to A, chromosome 2 at 74,699,273 bp
  • T to C, chromosome 2 at 85,579,341 bp
  • T to C, chromosome 3 at 126,930,020 bp
  • G to T, chromosome 4 at 97,783,601 bp
  • A to G, chromosome 4 at 137,956,533 bp
  • T to A, chromosome 5 at 21,683,431 bp
  • C to T, chromosome 5 at 44,177,134 bp
  • G to A, chromosome 5 at 114,367,337 bp
  • T to C, chromosome 5 at 137,528,699 bp
  • C to T, chromosome 6 at 129,675,354 bp
  • A to T, chromosome 7 at 19,591,109 bp
  • A to T, chromosome 7 at 44,209,645 bp
  • G to T, chromosome 7 at 81,025,033 bp
  • T to A, chromosome 7 at 98,716,393 bp
  • T to C, chromosome 8 at 79,070,442 bp
  • T to G, chromosome 9 at 8,103,439 bp
  • T to C, chromosome 9 at 109,223,290 bp
  • A to T, chromosome 9 at 109,233,600 bp
  • A to C, chromosome 10 at 129,473,426 bp
  • T to C, chromosome 11 at 20,726,955 bp
  • T to C, chromosome 11 at 48,866,237 bp
  • T to A, chromosome 11 at 80,471,492 bp
  • C to A, chromosome 11 at 100,084,986 bp
  • G to T, chromosome 11 at 114,864,267 bp
  • A to G, chromosome 12 at 70,990,497 bp
  • A to T, chromosome 12 at 73,112,350 bp
  • G to T, chromosome 13 at 24,092,550 bp
  • T to C, chromosome 14 at 55,944,520 bp
  • G to T, chromosome 15 at 10,551,550 bp
  • A to T, chromosome 15 at 95,894,524 bp
  • A to C, chromosome 15 at 99,232,974 bp
  • T to A, chromosome 15 at 101,794,829 bp
  • A to T, chromosome 16 at 14,706,726 bp
  • T to C, chromosome 17 at 12,709,445 bp
  • T to A, chromosome 17 at 14,369,048 bp
  • T to C, chromosome 17 at 23,385,968 bp
  • G to T, chromosome 18 at 88,995,569 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5794 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043385-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.