Strain Name:
C57BL/6J-MtgxR5796Btlr/Mmmh
Stock Number:
043387-MU
Citation ID:
RRID:MMRRC_043387-MU
Other Names:
R5796 (G1)
Major Collection:

Strain Information

Ptprk
Name: protein tyrosine phosphatase receptor type K
Synonyms: RPTPkappa, PTPk
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19272
VEGA: 10
HGNC: HGNC:9674
Homologene: 55693
Rps6kb1
Name: ribosomal protein S6 kinase, polypeptide 1
Synonyms: S6K1, p70/85s6k, p70s6k, p70S6K1, 2610318I15Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72508
Homologene: 81703
Katna1
Name: katanin p60 (ATPase-containing) subunit A1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 23924
HGNC: HGNC:6216
Homologene: 56014
Fbxo42
Name: F-box protein 42
Synonyms: 6720460I06Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 213499
Homologene: 16234
Gbf1
Name: golgi-specific brefeldin A-resistance factor 1
Synonyms: 1700083E03Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107338
HGNC: HGNC:4181
Homologene: 37897
Cyfip2
Name: cytoplasmic FMR1 interacting protein 2
Synonyms: 6430511D02Rik, Pir121, 1500004I01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76884
Homologene: 7936
Grb2
Name: growth factor receptor bound protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14784
HGNC: HGNC:4566
Homologene: 1576
Ap3d1
Name: adaptor-related protein complex 3, delta 1 subunit
Synonyms: mBLVR1, Bolvr
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11776
VEGA: 10
HGNC: HGNC:568
Homologene: 2926
Abcd3
Name: ATP-binding cassette, sub-family D member 3
Synonyms: PMP70, Pxmp1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19299
HGNC: HGNC:67
Homologene: 2140
Oxt
Name: oxytocin
Synonyms: Oxy
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18429
HGNC: HGNC:8528
Homologene: 55494
Recql5
Name: RecQ protein-like 5
Synonyms: Recql5b, Recq5b
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 170472
HGNC: HGNC:9950
Homologene: 31232
Hepacam2
Name: HEPACAM family member 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101202
Homologene: 18724
Tcf7
Name: transcription factor 7, T cell specific
Synonyms: T cell factor-1, Tcf1, TCF-1, T-cell factor 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21414
Homologene: 137220
Itfg1
Name: integrin alpha FG-GAP repeat containing 1
Synonyms: D8Wsu49e, 2310047C21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71927
Homologene: 12423
Smad5
Name: SMAD family member 5
Synonyms: Smad 5, Madh5, MusMLP
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17129
HGNC: HGNC:6771
Homologene: 4313
Rad54b
Name: RAD54 homolog B (S. cerevisiae)
Synonyms: E130016E03Rik, E130016E03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 623474
Homologene: 8240
Robo4
Name: roundabout guidance receptor 4
Synonyms: 1200012D01Rik, Magic roundabout
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74144
Homologene: 10397
Chct1
Name: CHD1 helical C-terminal domain containing 1
Synonyms: 1700125H20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 73634
Homologene: 18763
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Cacna1d
Name: calcium channel, voltage-dependent, L type, alpha 1D subunit
Synonyms: Cchl1a, D-LTCC, Cacnl1a2, 8430418G19Rik, Cav1.3alpha1, Cchl1a2, C79217
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12289
VEGA: 14
HGNC: HGNC:1391
Homologene: 578
Dclre1b
Name: DNA cross-link repair 1B
Synonyms: mSNM1B, SNMIB, Apollo
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 140917
Homologene: 32553
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: 2300002I04Rik, MUC5, MUC9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Nhsl1
Name: NHS like 1
Synonyms: 5730409E15Rik, D10Bwg0940e, A630035H13Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215819
Homologene: 27834
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Sppl2c
Name: signal peptide peptidase 2C
Synonyms: 4933407P14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237958
Homologene: 18491
Tuba3b
Name: tubulin, alpha 3B
Synonyms: Tuba7, M[a]7
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22147
Homologene: 128229
Vmn1r63
Name: vomeronasal 1 receptor 63
Synonyms: V1R1, V1rd1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 81017
Homologene: 41799
Efcab14
Name: EF-hand calcium binding domain 14
Synonyms: 4732418C07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230648
Homologene: 8858
Tbrg1
Name: transforming growth factor beta regulated gene 1
Synonyms: TB-5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 21376
Homologene: 18102
Dsc3
Name: desmocollin 3
Synonyms: 5430426I24Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13507
VEGA: 18
HGNC: HGNC:3037
Homologene: 1462
Crocc
Name: ciliary rootlet coiled-coil, rootletin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230872
Homologene: 16811
Gm20730
Name: predicted gene, 20730
Type: Gene
Species: Mouse
Chromosome: 6
Gm10549
Name: predicted gene 10549
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 433171
VEGA: 18
Klk1b26
Name: kallikrein 1-related petidase b26
Synonyms: Egfbp2, EGF-BP type B, mGK-26, Klk26, PRECE-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16618
Homologene: 68141
Cts3
Name: cathepsin 3
Synonyms: 1600000I23Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 117066
VEGA: 13
Ldhd
Name: lactate dehydrogenase D
Synonyms: D8Bwg1320e, 4733401P21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 52815
Homologene: 5536
Tgm2
Name: transglutaminase 2, C polypeptide
Synonyms: tTG, TG C, tissue transglutaminase, TG2, protein-glutamine gamma-glutamyltransferase, TGase2, tTGas, G[a]h
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21817
Homologene: 3391
Fgl1
Name: fibrinogen-like protein 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234199
HGNC: HGNC:3695
Homologene: 37927
Hsd3b9
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 9
Synonyms: Gm4450
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 100043461
Homologene: 104115
Nckipsd
Name: NCK interacting protein with SH3 domain
Synonyms: SPIN90, WISH, DIP1, ORF1, AF3P21, Wasbp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 80987
Homologene: 9514
Zfp382
Name: zinc finger protein 382
Synonyms: 5930415A09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233060
Homologene: 32798
Zmym3
Name: zinc finger, MYM-type 3
Synonyms: DXHXS6673E, 9030216B10Rik, Zfp261, DXS6673E, DXS6673El
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 56364
Homologene: 3736
Rbpjl
Name: recombination signal binding protein for immunoglobulin kappa J region-like
Synonyms: RBP-L, Rbpsuhl, RBP-J kappa-like
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19668
Homologene: 7512
Igkv4-55
Name: immunoglobulin kappa variable 4-55
Synonyms: LOC385253, Gm1524
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 385253
Gm17409
Name: predicted gene, 17409
Type: Gene
Species: Mouse
Chromosome: 2
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 2 at 58,471,022 bp
  • G to A, chromosome 2 at 130,576,613 bp
  • T to C, chromosome 2 at 158,118,904 bp
  • T to C, chromosome 2 at 164,410,248 bp
  • G to A, chromosome 2 at 181,340,506 bp
  • A to T, chromosome 3 at 98,446,852 bp
  • G to A, chromosome 3 at 103,807,457 bp
  • G to A, chromosome 3 at 121,784,498 bp
  • T to C, chromosome 3 at 124,421,428 bp
  • A to T, chromosome 4 at 11,615,446 bp
  • A to T, chromosome 4 at 115,746,583 bp
  • TCTGAGCTGCTGAGCTGC to TCTGAGCTGC, chromosome 4 at 141,041,807 bp
  • T to C, chromosome 4 at 141,199,789 bp
  • A to G, chromosome 4 at 143,615,208 bp
  • G to C, chromosome 6 at 3,466,200 bp
  • A to G, chromosome 6 at 43,081,530 bp
  • T to A, chromosome 6 at 69,607,448 bp
  • C to T, chromosome 6 at 145,619,682 bp
  • G to A, chromosome 7 at 5,803,141 bp
  • A to G, chromosome 7 at 30,133,349 bp
  • A to G, chromosome 7 at 43,533,056 bp
  • A to G, chromosome 7 at 44,016,328 bp
  • T to C, chromosome 7 at 130,467,268 bp
  • T to C, chromosome 7 at 141,857,396 bp
  • C to A, chromosome 8 at 20,901,982 bp
  • T to G, chromosome 8 at 41,199,759 bp
  • T to A, chromosome 8 at 85,718,893 bp
  • T to C, chromosome 8 at 111,627,090 bp
  • A to T, chromosome 9 at 37,411,674 bp
  • A to G, chromosome 9 at 37,652,575 bp
  • T to C, chromosome 9 at 79,703,829 bp
  • C to T, chromosome 9 at 108,126,024 bp
  • T to G, chromosome 9 at 108,811,614 bp
  • C to A, chromosome 10 at 7,760,811 bp
  • C to T, chromosome 10 at 18,524,250 bp
  • C to T, chromosome 10 at 28,383,575 bp
  • G to T, chromosome 10 at 80,714,037 bp
  • T to C, chromosome 11 at 46,198,996 bp
  • A to G, chromosome 11 at 52,261,527 bp
  • A to G, chromosome 11 at 85,173,275 bp
  • C to T, chromosome 11 at 86,511,851 bp
  • T to A, chromosome 11 at 104,187,793 bp
  • T to G, chromosome 11 at 115,645,872 bp
  • T to A, chromosome 11 at 115,927,865 bp
  • A to G, chromosome 13 at 56,723,832 bp
  • A to T, chromosome 13 at 61,568,703 bp
  • T to C, chromosome 14 at 30,066,116 bp
  • T to A, chromosome 18 at 19,971,501 bp
  • C to A, chromosome 18 at 33,464,305 bp
  • A to G, chromosome 19 at 7,457,467 bp
  • T to C, chromosome 19 at 46,284,343 bp
  • G to A, chromosome X at 101,415,800 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5796 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043387-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.