Strain Name:
C57BL/6J-MtgxR5840Btlr
Stock Number:
044060-MU
Citation ID:
RRID:MMRRC_044060-MU
Other Names:
R5840 (G1)
Major Collection:

Gene Information

Lamb1
Name: laminin B1
Synonyms: Lamb-1, C81607, C80098, D130003D08Rik, Lamb1-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 16777
HGNC: HGNC:6486
Homologene: 1722
Frem2
Name: Fras1 related extracellular matrix protein 2
Synonyms: 8430406N05Rik, 6030440P17Rik, my, ne, b2b1562Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242022
Homologene: 18454
Dip2c
Name: disco interacting protein 2 homolog C
Synonyms: 2900024P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 208440
Homologene: 40996
Gtf2a2
Name: general transcription factor II A, 2
Synonyms: TfIIg, 12kDa, Tfiia2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235459
HGNC: HGNC:4647
Homologene: 3304
Sema4b
Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
Synonyms: SemC, Semac
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20352
Homologene: 8426
Trpm7
Name: transient receptor potential cation channel, subfamily M, member 7
Synonyms: 5033407O22Rik, 4833414K03Rik, CHAK1, CHAK, TRP-PLIK, Ltpr7, 2310022G15Rik, LTRPC7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 58800
Homologene: 9774
Dab2ip
Name: disabled 2 interacting protein
Synonyms: 2310011D08Rik, AIP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69601
Homologene: 13058
Rcc2
Name: regulator of chromosome condensation 2
Synonyms: 2610529N02Rik, 2610510H01Rik, Td60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 108911
Homologene: 10282
Anapc1
Name: anaphase promoting complex subunit 1
Synonyms: tsg24, Apc1, 2610021O03Rik, Mcpr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17222
Homologene: 7414
Gng2
Name: guanine nucleotide binding protein (G protein), gamma 2
Synonyms: 1110003P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 14702
HGNC: HGNC:4404
Homologene: 40715
Ubxn4
Name: UBX domain protein 4
Synonyms: 1300013G12Rik, Ubxd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67812
Homologene: 40962
Fto
Name: fat mass and obesity associated
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 26383
Homologene: 8053
Stip1
Name: stress-induced phosphoprotein 1
Synonyms: p60, IEF SSP 3521, Hop, Hsp70/Hsp90 organizing protein, STI1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20867
VEGA: 19
Homologene: 4965
Ncapd3
Name: non-SMC condensin II complex, subunit D3
Synonyms: 4632407J06Rik, 2810487N22Rik, B130055D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 78658
VEGA: 9
Homologene: 41021
Nf2
Name: neurofibromin 2
Synonyms: schwannomin, moesin-ezrin-radixin-like protein, merlin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18016
HGNC: HGNC:7773
Homologene: 2180
Arhgap42
Name: Rho GTPase activating protein 42
Synonyms: 9030420J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71544
Homologene: 28446
N4bp2
Name: NEDD4 binding protein 2
Synonyms: LOC333789, LOC386488, B3bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 333789
Homologene: 32396
Aip
Name: aryl-hydrocarbon receptor-interacting protein
Synonyms: Ara9, Xap2, D19Bwg1412e, Fkbp16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 11632
HGNC: HGNC:358
Homologene: 2959
Chmp1a
Name: charged multivesicular body protein 1A
Synonyms: 2900018H07Rik, Pcoln3, chromatin modifying protein 1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234852
HGNC: HGNC:8740
Homologene: 56240
Zfp369
Name: zinc finger protein 369
Synonyms: NRIF2, D230020H11Rik, B930030B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 170936
Homologene: 129707
Pfkl
Name: phosphofructokinase, liver, B-type
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18641
HGNC: HGNC:8876
Homologene: 55668
Naa40
Name: N(alpha)-acetyltransferase 40, NatD catalytic subunit
Synonyms: 4931433E08Rik, Nat11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 70999
VEGA: 19
Homologene: 41588
Invs
Name: inversin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16348
Homologene: 7786
Rnase9
Name: ribonuclease, RNase A family, 9 (non-active)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 328401
VEGA: 14
Homologene: 18830
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, syne-2, D12Ertd777e, 6820443O06Rik, Nesp2g, Cpfl8, diminished cone electroretinogram, dice
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Trak2
Name: trafficking protein, kinesin binding 2
Synonyms: GRIF-1, CALS-C, OIP98, GRIF1, 4733401O11Rik, Als2cr3, 2900022D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70827
Homologene: 22861
Tgm5
Name: transglutaminase 5
Synonyms: 2310007C07Rik, TGx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74176
Homologene: 20899
Zfp608
Name: zinc finger protein 608
Synonyms: 4932417D18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 269023
VEGA: 18
Homologene: 18485
Ephb6
Name: Eph receptor B6
Synonyms: Mep, Cekl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13848
HGNC: HGNC:3396
Homologene: 20940
Elmo2
Name: engulfment and cell motility 2
Synonyms: 1190002F24Rik, CED-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 140579
Homologene: 44338
Kansl1l
Name: KAT8 regulatory NSL complex subunit 1-like
Synonyms: C430010P07Rik, 1110028C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68691
Homologene: 27376
Pde8a
Name: phosphodiesterase 8A
Synonyms: Pde8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18584
HGNC: HGNC:8793
Homologene: 1957
Thbs2
Name: thrombospondin 2
Synonyms: TSP2, Thbs-2, Thrombospondin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21826
VEGA: 17
Homologene: 2438
Lrit2
Name: leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
Synonyms: A930010E21Rik, Lrrc22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239038
VEGA: 14
Homologene: 18292
Abca2
Name: ATP-binding cassette, sub-family A (ABC1), member 2
Synonyms: Abc2, D2H0S1474E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11305
HGNC: HGNC:32
Homologene: 55590
Vrk2
Name: vaccinia related kinase 2
Synonyms: 2810003O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69922
Homologene: 55966
Srsf9
Name: serine and arginine-rich splicing factor 9
Synonyms: SRp30c, 2610029M16Rik, Sfrs9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 108014
Homologene: 20819
Or52s19
Name: olfactory receptor family 52 subfamily S member 19
Synonyms: GA_x6K02T2PBJ9-6068534-6067590, MOR24-3, Olfr601
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258311
Homologene: 64851
Axdnd1
Name: axonemal dynein light chain domain containing 1
Synonyms: LOC381304, 9430070O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 77352
Homologene: 52328
Pcdhb14
Name: protocadherin beta 14
Synonyms: Pcdhb17, PcdhbN, 2210006M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93885
Homologene: 70876
Or5b118
Name: olfactory receptor family 5 subfamily B member 118
Synonyms: GA_x6K02T2RE5P-3803583-3804527, MOR202-26P, MOR202-42, Olfr1474
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258123
Homologene: 79417
Klhl25
Name: kelch-like 25
Synonyms: 2810402K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 207952
Homologene: 32546
Foxred1
Name: FAD-dependent oxidoreductase domain containing 1
Synonyms: TEG-23, Tex23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235169
Homologene: 9712
Sptlc3
Name: serine palmitoyltransferase, long chain base subunit 3
Synonyms: C130053K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228677
Homologene: 105590
Cdca5
Name: cell division cycle associated 5
Synonyms: 2610036L13Rik, sororin p35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67849
Homologene: 49860
Itga2b
Name: integrin alpha 2b
Synonyms: platelet glycoprotein IIb, GpIIb, alphaIIb, CD41, GP IIb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16399
HGNC: HGNC:6138
Homologene: 37304
Psg18
Name: pregnancy specific beta-1-glycoprotein 18
Synonyms: mmCGM6, Cea-3, Cea3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26438
HGNC: HGNC:1816
Homologene: 110989
Nox4
Name: NADPH oxidase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 50490
HGNC: HGNC:7891
Homologene: 41065
Vmn1r172
Name: vomeronasal 1 receptor 172
Synonyms: V3R9, V1rd9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 81010
Homologene: 79577
BC005624
Name: cDNA sequence BC005624
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227707
Homologene: 9551
Cd177
Name: CD177 antigen
Synonyms: Pdp3, 1190003K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68891
Homologene: 49628
Gm17430
Name: predicted gene, 17430
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 118568368
VEGA: 18
Trbv21
Name: T cell receptor beta, variable 21
Synonyms: Gm16778, Tcrb-V19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100124686
Rhot2
Name: ras homolog family member T2
Synonyms: Miro2, Arht2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 214952
Homologene: 56038
Nt5c1b
Name: 5'-nucleotidase, cytosolic IB
Synonyms: 4921514H13Rik, CN-IB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 70881
Homologene: 12370
Loxl4
Name: lysyl oxidase-like 4
Synonyms: 4833426I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67573
Homologene: 12977
Ubqln5
Name: ubiquilin 5
Synonyms: 4931431F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70980
Homologene: 78030
Phc3
Name: polyhomeotic 3
Synonyms: EDR3, HPH3, E030046K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 241915
Homologene: 69390
Zc3h8
Name: zinc finger CCCH type containing 8
Synonyms: E130108N08Rik, Fliz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 57432
Homologene: 10759
Slc35d2
Name: solute carrier family 35, member D2
Synonyms: UGTrel8, SQV7L, hfrc, 5730408I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 70484
VEGA: 13
Homologene: 68119
Or52a33
Name: olfactory receptor family 52 subfamily A member 33
Synonyms: GA_x6K02T2PBJ9-6362863-6361910, MOR26-1, Olfr622
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259087
Homologene: 100540
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 58,919,273 bp
  • A to G, chromosome 1 at 66,770,215 bp
  • T to A, chromosome 1 at 128,259,525 bp
  • T to C, chromosome 1 at 156,348,958 bp
  • G to A, chromosome 2 at 25,433,359 bp
  • G to A, chromosome 2 at 30,981,857 bp
  • A to G, chromosome 2 at 35,727,499 bp
  • A to G, chromosome 2 at 121,085,660 bp
  • A to T, chromosome 2 at 126,822,611 bp
  • A to C, chromosome 2 at 128,607,037 bp
  • A to C, chromosome 2 at 128,929,904 bp
  • A to T, chromosome 2 at 139,547,206 bp
  • A to T, chromosome 2 at 165,295,552 bp
  • G to A, chromosome 3 at 30,936,583 bp
  • T to A, chromosome 3 at 53,647,921 bp
  • A to G, chromosome 4 at 48,396,284 bp
  • T to G, chromosome 4 at 140,712,138 bp
  • T to G, chromosome 5 at 65,808,094 bp
  • T to G, chromosome 5 at 115,331,465 bp
  • A to G, chromosome 6 at 41,202,858 bp
  • C to T, chromosome 6 at 41,615,573 bp
  • A to G, chromosome 7 at 18,346,602 bp
  • T to A, chromosome 7 at 23,660,175 bp
  • T to G, chromosome 7 at 24,758,070 bp
  • T to C, chromosome 7 at 75,866,692 bp
  • T to C, chromosome 7 at 80,218,949 bp
  • C to A, chromosome 7 at 81,213,965 bp
  • T to C, chromosome 7 at 87,360,793 bp
  • T to A, chromosome 7 at 103,358,369 bp
  • C to T, chromosome 7 at 103,639,256 bp
  • T to C, chromosome 7 at 104,128,954 bp
  • A to G, chromosome 8 at 91,666,440 bp
  • T to C, chromosome 8 at 123,208,100 bp
  • C to T, chromosome 9 at 9,046,517 bp
  • T to C, chromosome 9 at 27,094,758 bp
  • T to C, chromosome 9 at 35,210,139 bp
  • A to G, chromosome 9 at 70,015,293 bp
  • C to T, chromosome 10 at 77,988,724 bp
  • T to A, chromosome 11 at 4,816,146 bp
  • A to G, chromosome 11 at 26,534,314 bp
  • C to T, chromosome 11 at 102,461,331 bp
  • T to C, chromosome 12 at 10,377,171 bp
  • T to A, chromosome 12 at 31,266,756 bp
  • T to A, chromosome 12 at 75,880,291 bp
  • A to T, chromosome 13 at 9,506,676 bp
  • T to C, chromosome 13 at 64,118,413 bp
  • C to T, chromosome 13 at 65,297,278 bp
  • A to G, chromosome 14 at 19,875,814 bp
  • T to C, chromosome 14 at 37,069,005 bp
  • A to T, chromosome 14 at 51,038,988 bp
  • A to T, chromosome 17 at 14,681,430 bp
  • G to A, chromosome 17 at 25,840,058 bp
  • T to A, chromosome 18 at 9,726,528 bp
  • T to C, chromosome 18 at 37,448,750 bp
  • T to C, chromosome 18 at 54,898,906 bp
  • G to A, chromosome 19 at 4,116,010 bp
  • G to A, chromosome 19 at 6,090,369 bp
  • C to A, chromosome 19 at 7,022,068 bp
  • A to T, chromosome 19 at 7,230,008 bp
  • G to A, chromosome 19 at 13,471,878 bp
  • G to T, chromosome 19 at 42,598,715 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5840 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044060-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.