Strain Name:
C57BL/6J-MtgxR5851Btlr
Stock Number:
044067-MU
Citation ID:
RRID:MMRRC_044067-MU
Other Names:
R5851 (G1)
Major Collection:

Gene Information

Nfat5
Name: nuclear factor of activated T cells 5
Synonyms: TonEBP, nfatz, OREBP, B130038B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 54446
HGNC: HGNC:7774
Homologene: 4811
Myo1e
Name: myosin IE
Synonyms: 9130023P14Rik, 2310020N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71602
VEGA: 9
HGNC: HGNC:7599
Homologene: 55864
Ubap2
Name: ubiquitin-associated protein 2
Synonyms: 1190005K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 68926
Homologene: 73649
Fubp3
Name: far upstream element (FUSE) binding protein 3
Synonyms: A330051M14Rik, Marta2, FBP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 320267
HGNC: HGNC:4005
Homologene: 45954
Csrnp1
Name: cysteine-serine-rich nuclear protein 1
Synonyms: CSRNP-1, 4931429D10Rik, taip-3, Axud1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 215418
VEGA: 9
Homologene: 13196
Arhgef18
Name: rho/rac guanine nucleotide exchange factor (GEF) 18
Synonyms: A430078G23Rik, D030053O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 319493
Homologene: 32254
Paip1
Name: polyadenylate binding protein-interacting protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218693
Homologene: 4709
Lin9
Name: lin-9 homolog (C. elegans)
Synonyms: 2700022J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 72568
Homologene: 35252
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
Mtrex
Name: Mtr4 exosome RNA helicase
Synonyms: 2610528A15Rik, Skiv2l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 72198
VEGA: 13
Homologene: 6257
Nrf1
Name: nuclear respiratory factor 1
Synonyms: D6Ertd415e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 18181
HGNC: HGNC:7996
Homologene: 3674
Tmem245
Name: transmembrane protein 245
Synonyms: A630051L19Rik, D730040F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242474
HGNC: HGNC:1363
Homologene: 41841
Prmt2
Name: protein arginine N-methyltransferase 2
Synonyms: Hrmt1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 15468
HGNC: HGNC:5186
Homologene: 55587
Sla
Name: src-like adaptor
Synonyms: Slap-1, Slap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 20491
Homologene: 36206
Yju2
Name: YJU2 splicing factor
Synonyms: 2900016D05Rik, Ccdc94
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 72886
VEGA: 17
Homologene: 6350
Add3
Name: adducin 3 (gamma)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 27360
VEGA: 19
HGNC: HGNC:245
Homologene: 40893
C3
Name: complement component 3
Synonyms: Plp, acylation stimulating protein, complement factor 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12266
HGNC: HGNC:1318
Homologene: 68031
Rbl1
Name: RB transcriptional corepressor like 1
Synonyms: p107, retinoblastoma-like 1 (p107)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19650
HGNC: HGNC:9893
Homologene: 2172
Msh3
Name: mutS homolog 3
Synonyms: D13Em1, Rep-3, Rep3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17686
HGNC: HGNC:7326
Homologene: 1829
Nup160
Name: nucleoporin 160
Synonyms: Gtl1-13, 2810011M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 59015
Homologene: 32509
Edc4
Name: enhancer of mRNA decapping 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234699
Homologene: 40937
Zscan21
Name: zinc finger and SCAN domain containing 21
Synonyms: Zfp38, CTfin51, Zipro1, Zfp-38, RU49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22697
Homologene: 56530
Pcdhb10
Name: protocadherin beta 10
Synonyms: PcdhbJ, Pcdhb5D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93881
HGNC: HGNC:8690
Homologene: 88834
Slc46a2
Name: solute carrier family 46, member 2
Synonyms: 5430429N04Rik, Tscot, TSO-1C12, Ly110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 30936
Homologene: 23273
Pdzph1
Name: PDZ and pleckstrin homology domains 1
Synonyms: 2610034M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 69239
Homologene: 130756
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380698
Homologene: 70869
Tas2r123
Name: taste receptor, type 2, member 123
Synonyms: mGR23, T2R23, mt2r55, Tas2r23, STC 9-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 353167
Homologene: 45450
Slc6a19
Name: solute carrier family 6 (neurotransmitter transporter), member 19
Synonyms: B0AT1, 4632401C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 74338
Homologene: 52819
Olfr638
Name: olfactory receptor 638
Synonyms: MOR5-1, GA_x6K02T2PBJ9-6737723-6738670
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259124
Homologene: 133592
Abca2
Name: ATP-binding cassette, sub-family A (ABC1), member 2
Synonyms: D2H0S1474E, Abc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11305
HGNC: HGNC:32
Homologene: 55590
Ttc28
Name: tetratricopeptide repeat domain 28
Synonyms: 2310015L07Rik, TPRBK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 209683
Homologene: 41023
Sdk1
Name: sidekick cell adhesion molecule 1
Synonyms: 6720466O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330222
Homologene: 27395
Garem2
Name: GRB2 associated regulator of MAPK1 subtype 2
Synonyms: Fam59b, LOC242915, Gareml
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 242915
Homologene: 19063
Zfp954
Name: zinc finger protein 954
Synonyms: 5730403M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232853
Homologene: 129792
Cmpk1
Name: cytidine monophosphate (UMP-CMP) kinase 1
Synonyms: 0610011D08Rik, Cmpk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 66588
Homologene: 32308
Cdkl1
Name: cyclin-dependent kinase-like 1 (CDC2-related kinase)
Synonyms: 4933411O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 71091
VEGA: 12
HGNC: HGNC:1781
Homologene: 55805
Tor2a
Name: torsin family 2, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 30933
Homologene: 25260
Itga2b
Name: integrin alpha 2b
Synonyms: GP IIb, CD41, platelet glycoprotein IIb, GpIIb, alphaIIb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16399
HGNC: HGNC:6138
Homologene: 37304
Klhl33
Name: kelch-like 33
Synonyms: EG546611
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 546611
VEGA: 14
Homologene: 52385
Cd163l1
Name: CD163 molecule-like 1
Synonyms: E430002D04Rik, Scart1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244233
Homologene: 129778
Slc5a9
Name: solute carrier family 5 (sodium/glucose cotransporter), member 9
Synonyms: SGLT4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230612
Homologene: 17081
Sele
Name: selectin, endothelial cell
Synonyms: E-selectin, CD62E, Elam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20339
Homologene: 389
Ceacam1
Name: carcinoembryonic antigen-related cell adhesion molecule 1
Synonyms: Cc1, C-CAM, Cea-7, Hv-2, CD66a, MHVR1, mmCGM1, mCEA1, mmCGM2, Cea-1, Cea1, Mhv-1, Bgp1, Bgp, Cea7, Hv2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 26365
HGNC: HGNC:1814
Homologene: 128630
Celf3
Name: CUGBP, Elav-like family member 3
Synonyms: 4930415M08Rik, ERDA4, Tnrc4, CAGH4, BRUNOL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 78784
Homologene: 48510
H2-Eb1
Name: histocompatibility 2, class II antigen E beta
Synonyms: H-2Eb, Ia-4, Ia4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14969
HGNC: HGNC:4953
Homologene: 101524
Pnlip
Name: pancreatic lipase
Synonyms: pancreatic triglyceride lipase, 1810007A24Rik, PTL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 69060
VEGA: 19
HGNC: HGNC:9155
Homologene: 30999
Rfk
Name: riboflavin kinase
Synonyms: 0610038L10Rik, ATP:riboflavin 5'-phosphotransferase, flavokinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 54391
Homologene: 115690
Pate2
Name: prostate and testis expressed 2
Synonyms: mANLP1, LOC330921
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 330921
Homologene: 86016
Efcab1
Name: EF-hand calcium binding domain 1
Synonyms: 4930449A16Rik, 5430404L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 66793
VEGA: 16
Homologene: 11608
Ifnl3
Name: interferon lambda 3
Synonyms: Il28b, IFL-1, Il28, INF-lambda
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 338374
Homologene: 77540
Abhd15
Name: abhydrolase domain containing 15
Synonyms: 1300007F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67477
Homologene: 12142
Fam174a
Name: family with sequence similarity 174, member A
Synonyms: Tmem157, 2310044D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 67698
Homologene: 12175
Olfr1184
Name: olfactory receptor 1184
Synonyms: GA_x6K02T2Q125-49974190-49975125, MOR225-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258820
Homologene: 73980
Trav6-3
Name: T cell receptor alpha variable 6-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 328483
4930404N11Rik
Name: RIKEN cDNA 4930404N11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 432479
Homologene: 47801
Lor
Name: loricrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 16939
HGNC: HGNC:6663
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 95,325,143 bp
  • A to G, chromosome 1 at 164,049,574 bp
  • T to A, chromosome 1 at 180,669,198 bp
  • A to G, chromosome 2 at 25,442,310 bp
  • T to A, chromosome 2 at 31,598,610 bp
  • A to T, chromosome 2 at 32,761,607 bp
  • A to G, chromosome 2 at 88,486,860 bp
  • A to G, chromosome 2 at 90,707,038 bp
  • T to A, chromosome 2 at 157,167,325 bp
  • G to A, chromosome 3 at 92,080,539 bp
  • T to A, chromosome 3 at 94,479,126 bp
  • G to A, chromosome 4 at 41,206,268 bp
  • T to C, chromosome 4 at 56,916,770 bp
  • A to G, chromosome 4 at 59,913,906 bp
  • A to G, chromosome 4 at 111,885,600 bp
  • A to G, chromosome 4 at 114,986,970 bp
  • C to T, chromosome 5 at 30,114,290 bp
  • G to A, chromosome 5 at 111,235,469 bp
  • A to G, chromosome 5 at 138,126,478 bp
  • G to A, chromosome 5 at 141,962,669 bp
  • A to G, chromosome 6 at 30,089,976 bp
  • T to C, chromosome 6 at 132,847,308 bp
  • C to A, chromosome 7 at 7,115,625 bp
  • T to C, chromosome 7 at 25,474,600 bp
  • G to T, chromosome 7 at 28,523,511 bp
  • A to G, chromosome 7 at 104,003,452 bp
  • A to G, chromosome 7 at 120,039,362 bp
  • C to T, chromosome 7 at 140,228,027 bp
  • T to C, chromosome 8 at 3,434,980 bp
  • T to C, chromosome 8 at 105,890,867 bp
  • G to T, chromosome 8 at 107,347,727 bp
  • T to A, chromosome 9 at 35,670,501 bp
  • G to A, chromosome 9 at 70,383,804 bp
  • C to T, chromosome 9 at 119,973,078 bp
  • C to A, chromosome 10 at 76,236,740 bp
  • A to T, chromosome 10 at 81,364,877 bp
  • A to T, chromosome 11 at 58,994,700 bp
  • T to C, chromosome 11 at 77,518,447 bp
  • C to A, chromosome 11 at 102,457,601 bp
  • A to T, chromosome 11 at 107,110,862 bp
  • A to T, chromosome 12 at 69,756,564 bp
  • A to G, chromosome 13 at 73,691,740 bp
  • G to T, chromosome 13 at 92,215,522 bp
  • G to A, chromosome 13 at 112,908,952 bp
  • T to C, chromosome 13 at 119,440,765 bp
  • A to T, chromosome 14 at 50,892,878 bp
  • A to G, chromosome 14 at 53,430,115 bp
  • G to A, chromosome 15 at 66,783,723 bp
  • T to A, chromosome 16 at 14,920,436 bp
  • C to T, chromosome 17 at 34,309,771 bp
  • C to T, chromosome 17 at 55,967,582 bp
  • T to C, chromosome 17 at 57,211,612 bp
  • T to G, chromosome 17 at 58,973,746 bp
  • A to G, chromosome 18 at 37,412,758 bp
  • C to T, chromosome 19 at 17,395,198 bp
  • T to C, chromosome 19 at 53,236,774 bp
  • G to A, chromosome 19 at 58,673,792 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5851 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044067-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.