Strain Name:
C57BL/6J-MtgxR5909Btlr
Stock Number:
044106-MU
Citation ID:
RRID:MMRRC_044106-MU
Other Names:
R5909 (G1)
Major Collection:

Gene Information

Fancd2
Name: Fanconi anemia, complementation group D2
Synonyms: 2410150O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 211651
HGNC: HGNC:3585
Homologene: 13212
Ylpm1
Name: YLP motif containing 1
Synonyms: ZAP, A930013E17Rik, Zap3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 56531
Homologene: 87707
Plxnd1
Name: plexin D1
Synonyms: 6230425C21Rik, b2b553Clo, b2b1863Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67784
HGNC: HGNC:9107
Homologene: 22866
Rbm25
Name: RNA binding motif protein 25
Synonyms: 2610015J01Rik, A130095G20Rik, 2600011C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 67039
Naa15
Name: N(alpha)-acetyltransferase 15, NatA auxiliary subunit
Synonyms: Narg1, tubedown, mNAT1, ASTBDN, Tbdn-1, 5730450D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74838
Homologene: 14211
Rcc2
Name: regulator of chromosome condensation 2
Synonyms: 2610529N02Rik, Td60, 2610510H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 108911
Homologene: 10282
Lrch4
Name: leucine-rich repeats and calponin homology (CH) domain containing 4
Synonyms: SAP25, LRN, 2810008P14Rik, LRRN4, 2900069C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231798
HGNC: HGNC:6691
Homologene: 20532
Sulf1
Name: sulfatase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240725
Homologene: 49408
Ddx55
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
Synonyms: 2810021H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 67848
Homologene: 12196
Stat3
Name: signal transducer and activator of transcription 3
Synonyms: Aprf, 1110034C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20848
Homologene: 7960
Srrm2
Name: serine/arginine repetitive matrix 2
Synonyms: 5033413A03Rik, SRm300
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 75956
Phkb
Name: phosphorylase kinase beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 102093
HGNC: HGNC:8927
Homologene: 247
Fnbp1
Name: formin binding protein 1
Synonyms: 2210010H06Rik, FBP1, 1110057E06Rik, FBP17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14269
Homologene: 100983
Bdp1
Name: B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
Synonyms: B130055N23Rik, TFIIIB90, TAF3B1, Tfnr, G630013P12Rik, TFIIIB150, TFC5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 544971
Homologene: 34582
Bcl6
Name: B cell leukemia/lymphoma 6
Synonyms: Bcl5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12053
HGNC: HGNC:1001
Homologene: 7640
Plxna4
Name: plexin A4
Synonyms: Plxa4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 243743
HGNC: HGNC:9102
Homologene: 77587
Unc5b
Name: unc-5 netrin receptor B
Synonyms: Unc5h2, 6330415E02Rik, D10Bwg0792e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 107449
VEGA: 10
Homologene: 32538
Etnk1
Name: ethanolamine kinase 1
Synonyms: 4930555L11Rik, 1110061E11Rik, EKI1, D6Ertd3e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 75320
Homologene: 10240
Jak3
Name: Janus kinase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16453
HGNC: HGNC:6193
Homologene: 181
Zbtb10
Name: zinc finger and BTB domain containing 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229055
Homologene: 11395
Trmt61a
Name: tRNA methyltransferase 61A
Synonyms: 6720458F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 328162
VEGA: 12
Homologene: 6229
Tbc1d2
Name: TBC1 domain family, member 2
Synonyms: PARIS-1, PARIS1, A630005A06Rik, LOC381605
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381605
Homologene: 10190
Isx
Name: intestine specific homeobox
Synonyms: 9130012O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 71597
Homologene: 28312
Trim17
Name: tripartite motif-containing 17
Synonyms: Rnf16, terf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 56631
Homologene: 9387
Siglec1
Name: sialic acid binding Ig-like lectin 1, sialoadhesin
Synonyms: Sn, Siglec-1, CD169
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20612
Homologene: 124458
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Kdm5d
Name: lysine (K)-specific demethylase 5D
Synonyms: Jarid1d, Smcy, HY
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
Alteration at locus: Chemically Induced
NCBI: 20592
Homologene: 55838
Glce
Name: glucuronyl C5-epimerase
Synonyms: heparan sulfate-glucuronic acid C5-epimerase, 1110017N23Rik, C130034A12Rik, Hsepi
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 93683
Homologene: 14111
Pkdrej
Name: polycystin (PKD) family receptor for egg jelly
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18766
VEGA: 15
HGNC: HGNC:9015
Homologene: 4427
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: PKHDL1, fibrocystin L, D86 mRNA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 192190
Homologene: 16332
Krt35
Name: keratin 35
Synonyms: Krt1-24, Ha5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 53617
HGNC: HGNC:6453
Homologene: 1715
Nudt8
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 8
Synonyms: 2310039H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 66387
VEGA: 19
HGNC: HGNC:8055
Homologene: 41633
Astn1
Name: astrotactin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11899
HGNC: HGNC:773
Homologene: 7233
Exoc3
Name: exocyst complex component 3
Synonyms: Sec6l1, E430013E20Rik, 2810050O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 211446
VEGA: 13
Homologene: 38296
Oas1e
Name: 2'-5' oligoadenylate synthetase 1E
Synonyms: 2'-5' oligoadenylate synthetase-like 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231699
HGNC: HGNC:8086
Homologene: 110815
Impg2
Name: interphotoreceptor matrix proteoglycan 2
Synonyms: PG10.2, IPM200, Spacrcan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224224
Homologene: 9439
Tmem145
Name: transmembrane protein 145
Synonyms: B930076A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 330485
Homologene: 18333
Fbll1
Name: fibrillarin-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237730
Homologene: 28185
Mybpc2
Name: myosin binding protein C, fast-type
Synonyms: Fast-type C-protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233199
HGNC: HGNC:7550
Homologene: 3331
Atp1a2
Name: ATPase, Na+/K+ transporting, alpha 2 polypeptide
Synonyms: Atpa-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98660
HGNC: HGNC:800
Homologene: 47947
Ofcc1
Name: orofacial cleft 1 candidate 1
Synonyms: Opo, ojoplano
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218165
VEGA: 13
Homologene: 125376
Olfr1179
Name: olfactory receptor 1179
Synonyms: MOR225-2, GA_x6K02T2Q125-49890854-49889931
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258919
Homologene: 74070
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 76645
Homologene: 124481
F830016B08Rik
Name: RIKEN cDNA F830016B08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240328
VEGA: 18
Homologene: 129714
Cpvl
Name: carboxypeptidase, vitellogenic-like
Synonyms: 4933436L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 71287
Homologene: 80235
Adcy7
Name: adenylate cyclase 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11513
HGNC: HGNC:238
Homologene: 866
Alcam
Name: activated leukocyte cell adhesion molecule
Synonyms: BEN, SC1, CD166, DM-GRASP, MuSC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 11658
HGNC: HGNC:400
Homologene: 1229
Pidd1
Name: p53 induced death domain protein 1
Synonyms: Pidd, Lrdd, 1200011D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 57913
Homologene: 11220
Prdm13
Name: PR domain containing 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230025
Homologene: 11000
Vmn1r66
Name: vomeronasal 1 receptor 66
Synonyms: V1re11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 171264
Mup3
Name: major urinary protein 3
Synonyms: Mup-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 17842
Homologene: 74304
Trim43b
Name: tripartite motif-containing 43B
Synonyms: Gm8269
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 666747
Homologene: 105432
Olfr48
Name: olfactory receptor 48
Synonyms: MOR232-5, GA_x6K02T2Q125-51285881-51284976, IC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18347
Homologene: 85936
Sox13
Name: SRY (sex determining region Y)-box 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20668
Homologene: 4159
Mcat
Name: malonyl CoA:ACP acyltransferase (mitochondrial)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223722
VEGA: 15
Homologene: 15511
Ero1lb
Name: ERO1-like beta (S. cerevisiae)
Synonyms: 1300013B24Rik, 1700065B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 67475
VEGA: 13
Homologene: 8740
Adamts8
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
Synonyms: METH2, METH-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 30806
HGNC: HGNC:224
Homologene: 5108
Zfp493
Name: zinc finger protein 493
Synonyms: 2900054J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 72958
Gm14548
Name: predicted gene 14548
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100038909
HGNC: HGNC:6607
Homologene: 134028
Maneal
Name: mannosidase, endo-alpha-like
Synonyms: LOC215090
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 215090
Homologene: 17597
Ift20
Name: intraflagellar transport 20
Synonyms: 0610009H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 55978
Homologene: 49559
Gm29096
Name: predicted gene 29096
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 12,858,815 bp
  • A to G, chromosome 1 at 133,383,889 bp
  • A to C, chromosome 1 at 158,601,937 bp
  • A to T, chromosome 1 at 172,287,230 bp
  • A to G, chromosome 2 at 31,048,199 bp
  • A to T, chromosome 2 at 88,402,191 bp
  • A to G, chromosome 2 at 89,844,391 bp
  • A to T, chromosome 2 at 131,077,964 bp
  • T to C, chromosome 3 at 9,280,049 bp
  • T to C, chromosome 3 at 51,460,064 bp
  • G to T, chromosome 4 at 21,683,894 bp
  • C to T, chromosome 4 at 46,629,912 bp
  • T to G, chromosome 4 at 62,086,007 bp
  • A to T, chromosome 4 at 124,857,173 bp
  • T to A, chromosome 4 at 140,717,068 bp
  • A to T, chromosome 5 at 120,788,907 bp
  • T to C, chromosome 5 at 124,566,850 bp
  • T to C, chromosome 5 at 137,633,865 bp
  • A to G, chromosome 6 at 32,517,246 bp
  • T to C, chromosome 6 at 53,932,428 bp
  • T to A, chromosome 6 at 113,561,711 bp
  • G to T, chromosome 6 at 115,968,688 bp
  • A to G, chromosome 6 at 143,197,438 bp
  • G to A, chromosome 7 at 3,897,622 bp
  • A to T, chromosome 7 at 10,274,342 bp
  • G to T, chromosome 7 at 25,308,193 bp
  • G to A, chromosome 7 at 44,507,091 bp
  • A to C, chromosome 7 at 141,441,270 bp
  • A to G, chromosome 8 at 71,684,231 bp
  • A to G, chromosome 8 at 74,892,798 bp
  • G to T, chromosome 8 at 86,021,447 bp
  • A to T, chromosome 8 at 88,325,496 bp
  • G to A, chromosome 8 at 117,024,056 bp
  • T to C, chromosome 9 at 30,961,928 bp
  • G to T, chromosome 9 at 62,060,144 bp
  • A to T, chromosome 9 at 89,085,398 bp
  • G to A, chromosome 10 at 39,072,859 bp
  • T to C, chromosome 10 at 41,561,115 bp
  • A to C, chromosome 10 at 60,772,359 bp
  • G to A, chromosome 11 at 35,798,332 bp
  • A to T, chromosome 11 at 58,968,680 bp
  • T to A, chromosome 11 at 78,540,041 bp
  • A to T, chromosome 11 at 100,095,813 bp
  • G to A, chromosome 11 at 100,903,730 bp
  • T to A, chromosome 12 at 83,681,588 bp
  • C to T, chromosome 12 at 85,040,886 bp
  • C to A, chromosome 12 at 111,680,858 bp
  • A to G, chromosome 13 at 12,579,258 bp
  • A to G, chromosome 13 at 40,263,578 bp
  • T to A, chromosome 13 at 67,786,598 bp
  • A to G, chromosome 13 at 74,199,524 bp
  • A to G, chromosome 13 at 100,092,286 bp
  • G to T, chromosome 15 at 44,526,763 bp
  • C to T, chromosome 15 at 83,547,915 bp
  • A to T, chromosome 15 at 85,818,296 bp
  • A to G, chromosome 16 at 23,972,806 bp
  • G to T, chromosome 16 at 52,290,993 bp
  • T to C, chromosome 16 at 56,258,136 bp
  • T to C, chromosome 17 at 23,821,317 bp
  • T to A, chromosome 18 at 60,300,019 bp
  • T to C, chromosome 19 at 4,000,727 bp
  • G to A, chromosome Y at 941,306 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5909 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044106-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.