Strain Name:
C57BL/6J-MtgxR5924Btlr
Stock Number:
044119-MU
Citation ID:
RRID:MMRRC_044119-MU
Other Names:
R5924 (G1)
Major Collection:

Gene Information

Utp20
Name: UTP20 small subunit processome component
Synonyms: 3830408P06Rik, mDRIM, DRIM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70683
VEGA: 10
Homologene: 38373
Strn4
Name: striatin, calmodulin binding protein 4
Synonyms: zinedin, ZIN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 97387
Homologene: 8378
Col6a1
Name: collagen, type VI, alpha 1
Synonyms: Col6a-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12833
HGNC: HGNC:2211
Homologene: 1391
Mtmr14
Name: myotubularin related protein 14
Synonyms: 1110061O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 97287
Homologene: 11203
Ggnbp2
Name: gametogenetin binding protein 2
Synonyms: DIF-3, Zfp403, D330017P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217039
Homologene: 11750
Nsfl1c
Name: NSFL1 (p97) cofactor (p47)
Synonyms: p47
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 386649
Homologene: 41114
Tacr3
Name: tachykinin receptor 3
Synonyms: neuromedin K receptor, Nk3r, Tac3r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 21338
Homologene: 824
Gk5
Name: glycerol kinase 5 (putative)
Synonyms: C330018K18Rik, G630067D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235533
Homologene: 15141
Eif4g3
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: 1500002J22Rik, 4930523M17Rik, repro8, G1-419-52, eIF4GII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230861
HGNC: HGNC:3298
Homologene: 2789
Setd2
Name: SET domain containing 2
Synonyms: 4921524K10Rik, KMT3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235626
Homologene: 56493
Flnb
Name: filamin, beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 286940
HGNC: HGNC:3755
Homologene: 37480
Eefsec
Name: eukaryotic elongation factor, selenocysteine-tRNA-specific
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 65967
Homologene: 11073
Mier1
Name: MEIR1 treanscription regulator
Synonyms: 4933425I22Rik, 5830411K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 71148
Homologene: 136176
Cep78
Name: centrosomal protein 78
Synonyms: 5730599I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 208518
VEGA: 19
Homologene: 11030
Prom1
Name: prominin 1
Synonyms: 4932416E19Rik, Prom-1, Prom, CD133, AC133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19126
HGNC: HGNC:9454
Homologene: 4390
Stim2
Name: stromal interaction molecule 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 116873
Homologene: 32490
Hras
Name: Harvey rat sarcoma virus oncogene
Synonyms: c-H-ras, Hras1, Harvey-ras, Hras-1, H-ras, c-rasHa, Ha-ras
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15461
HGNC: HGNC:5173
Homologene: 55890
Abhd3
Name: abhydrolase domain containing 3
Synonyms: LABH3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 106861
Homologene: 14055
Rasal1
Name: RAS protein activator like 1 (GAP1 like)
Synonyms: MRASAL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19415
HGNC: HGNC:9873
Homologene: 3423
Lpin1
Name: lipin 1
Synonyms: Lipin1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 14245
VEGA: 12
Homologene: 9266
Olfm3
Name: olfactomedin 3
Synonyms: optimedin, B230206G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229759
Homologene: 17103
Lifr
Name: LIF receptor alpha
Synonyms: soluble differentiation-stimulating factor receptor, A230075M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16880
VEGA: 15
HGNC: HGNC:6597
Homologene: 1735
Pkd2
Name: polycystin 2, transient receptor potential cation channel
Synonyms: PC2, C030034P18Rik, polycystin-2, TRPP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18764
HGNC: HGNC:9009
Homologene: 20104
Dcakd
Name: dephospho-CoA kinase domain containing
Synonyms: 3010024O21Rik, 6720485C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68087
Homologene: 5652
Magi3
Name: membrane associated guanylate kinase, WW and PDZ domain containing 3
Synonyms: 6530407C02Rik, 4732496O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99470
Homologene: 26431
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: Hapip, E530005C20Rik, 2210407G14Rik, LOC224126
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Esrp1
Name: epithelial splicing regulatory protein 1
Synonyms: Rbm35a, 2210008M09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 207920
Homologene: 9785
Pik3ap1
Name: phosphoinositide-3-kinase adaptor protein 1
Synonyms: 1810044J04Rik, BCAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 83490
VEGA: 19
Homologene: 12848
Ddr2
Name: discoidin domain receptor family, member 2
Synonyms: Ntrkr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18214
HGNC: HGNC:2731
Homologene: 68505
Myof
Name: myoferlin
Synonyms: 2310051D19Rik, Fer1l3, E030042N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226101
VEGA: 19
HGNC: HGNC:3656
Homologene: 40882
Bnip2
Name: BCL2/adenovirus E1B interacting protein 2
Synonyms: 5730523P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12175
HGNC: HGNC:1083
Homologene: 3194
Pigo
Name: phosphatidylinositol glycan anchor biosynthesis, class O
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56703
Homologene: 31761
Epha5
Name: Eph receptor A5
Synonyms: bsk, Rek7, Cek7, Els1, Hek7, Ehk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13839
HGNC: HGNC:3389
Homologene: 55824
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b1154Clo, b2b3491Clo, Dnahc5, b2b1537Clo, b2b1565Clo, b2b1134Clo, Mdnah5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Agbl1
Name: ATP/GTP binding protein-like 1
Synonyms: EG244071, Nna1-l1, Ccp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244071
Homologene: 17552
Magi2
Name: membrane associated guanylate kinase, WW and PDZ domain containing 2
Synonyms: Acvrinp1, Magi-2, S-SCAM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 50791
Homologene: 8189
Art3
Name: ADP-ribosyltransferase 3
Synonyms: 4930569O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 109979
HGNC: HGNC:725
Homologene: 911
V1rd19
Name: vomeronasal 1 receptor, D19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 404287
Homologene: 104166
Slc24a2
Name: solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
Synonyms: 6330417K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76376
Homologene: 10669
Cdhr2
Name: cadherin-related family member 2
Synonyms: LOC268663, Pcdh24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 268663
Homologene: 134510
Opn5
Name: opsin 5
Synonyms: Gpr136, Neuropsin, TMEM13, PGR12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 353344
VEGA: 17
Homologene: 72341
Slc51a
Name: solute carrier family 51, alpha subunit
Synonyms: D630035O19Rik, OSTalpha, Osta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 106407
Homologene: 44941
Zup1
Name: zinc finger containing ubiquitin peptidase 1
Synonyms: Zufsp, 2700019D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 72580
VEGA: 10
Homologene: 12472
Olfr1170
Name: olfactory receptor 1170
Synonyms: MOR174-12, GA_x6K02T2Q125-49709783-49708833
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258525
Homologene: 138307
Slc28a1
Name: solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
Synonyms: Cnt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434203
Homologene: 37902
Apc2
Name: APC regulator of WNT signaling pathway 2
Synonyms: APCL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 23805
Homologene: 4299
Vmn2r4
Name: vomeronasal 2, receptor 4
Synonyms: EG637053
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 637053
Homologene: 129754
Fndc1
Name: fibronectin type III domain containing 1
Synonyms: 1110027O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 68655
Gpr137
Name: G protein-coupled receptor 137
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107173
VEGA: 19
Homologene: 10598
Slco2a1
Name: solute carrier organic anion transporter family, member 2a1
Synonyms: 2310021C19Rik, mPgt, Pgt, Slc21a2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 24059
Homologene: 38077
Cyp3a44
Name: cytochrome P450, family 3, subfamily a, polypeptide 44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 337924
HGNC: HGNC:2638
Homologene: 133568
Olfr727
Name: olfactory receptor 727
Synonyms: GA_x6K02T2PMLR-5817082-5818056, MOR246-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258316
Homologene: 84571
B4galnt4
Name: beta-1,4-N-acetyl-galactosaminyl transferase 4
Synonyms: LOC381951
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330671
Homologene: 27982
Nlrp6
Name: NLR family, pyrin domain containing 6
Synonyms: Nalp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101613
Homologene: 15881
Olfr131
Name: olfactory receptor 131
Synonyms: GA_x6K02T2PSCP-2531299-2530355, MOR256-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258867
Homologene: 105889
Speer4f2
Name: spermatogenesis associated glutamate (E)-rich protein 4f2
Synonyms: Gm3535, Gm3495
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100041749
Sebox
Name: SEBOX homeobox
Synonyms: OG9, Og9x
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18292
Homologene: 32052
Gpt2
Name: glutamic pyruvate transaminase (alanine aminotransferase) 2
Synonyms: 4631422C05Rik, ALT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 108682
Homologene: 68832
Pax8
Name: paired box 8
Synonyms: Pax-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18510
HGNC: HGNC:8622
Homologene: 2589
Ighv1-36
Name: immunoglobulin heavy variable 1-36
Synonyms: Gm16715
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 629897
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 169,994,628 bp
  • A to G, chromosome 2 at 24,421,622 bp
  • T to C, chromosome 2 at 88,224,547 bp
  • T to A, chromosome 2 at 151,505,400 bp
  • C to T, chromosome 3 at 64,389,264 bp
  • A to T, chromosome 3 at 104,054,538 bp
  • A to T, chromosome 3 at 115,122,538 bp
  • G to T, chromosome 3 at 134,932,299 bp
  • G to T, chromosome 4 at 11,361,174 bp
  • G to A, chromosome 4 at 43,023,389 bp
  • A to T, chromosome 4 at 87,011,588 bp
  • T to A, chromosome 4 at 103,159,702 bp
  • T to G, chromosome 4 at 138,201,926 bp
  • A to G, chromosome 5 at 17,376,624 bp
  • A to C, chromosome 5 at 20,611,069 bp
  • T to C, chromosome 5 at 44,004,963 bp
  • A to G, chromosome 5 at 54,102,643 bp
  • A to T, chromosome 5 at 84,233,674 bp
  • A to T, chromosome 5 at 92,412,232 bp
  • A to G, chromosome 5 at 104,498,558 bp
  • T to C, chromosome 5 at 120,675,517 bp
  • A to T, chromosome 5 at 145,794,327 bp
  • A to T, chromosome 6 at 88,355,547 bp
  • A to G, chromosome 6 at 113,253,789 bp
  • T to C, chromosome 7 at 16,838,321 bp
  • C to T, chromosome 7 at 24,003,949 bp
  • C to T, chromosome 7 at 76,409,234 bp
  • G to T, chromosome 7 at 81,115,612 bp
  • T to C, chromosome 7 at 140,923,490 bp
  • A to G, chromosome 7 at 141,070,829 bp
  • C to T, chromosome 7 at 141,192,461 bp
  • C to A, chromosome 8 at 85,493,004 bp
  • A to G, chromosome 9 at 69,997,162 bp
  • T to C, chromosome 9 at 96,150,510 bp
  • T to A, chromosome 9 at 103,046,699 bp
  • A to T, chromosome 9 at 110,574,044 bp
  • A to T, chromosome 10 at 33,927,547 bp
  • A to G, chromosome 10 at 76,718,371 bp
  • A to T, chromosome 10 at 80,312,150 bp
  • G to A, chromosome 10 at 88,815,922 bp
  • T to C, chromosome 11 at 78,504,191 bp
  • A to G, chromosome 11 at 84,858,537 bp
  • C to A, chromosome 11 at 102,999,820 bp
  • A to T, chromosome 12 at 16,544,657 bp
  • G to A, chromosome 12 at 114,880,157 bp
  • A to C, chromosome 13 at 54,726,683 bp
  • T to A, chromosome 14 at 7,890,765 bp
  • A to G, chromosome 14 at 50,126,682 bp
  • A to G, chromosome 15 at 7,172,972 bp
  • A to T, chromosome 15 at 28,307,327 bp
  • A to G, chromosome 16 at 32,477,172 bp
  • G to A, chromosome 16 at 34,243,833 bp
  • T to A, chromosome 17 at 7,773,610 bp
  • A to G, chromosome 17 at 38,082,363 bp
  • A to T, chromosome 17 at 42,611,308 bp
  • T to C, chromosome 18 at 10,706,085 bp
  • A to G, chromosome 19 at 6,939,361 bp
  • A to T, chromosome 19 at 15,961,066 bp
  • A to T, chromosome 19 at 37,982,973 bp
  • A to C, chromosome 19 at 41,296,456 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5924 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044119-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.