Strain Name:
C57BL/6J-MtgxR5958Btlr/Mmmh
Stock Number:
044145-MU
Citation ID:
RRID:MMRRC_044145-MU
Other Names:
R5958 (G1)
Major Collection:

Gene Information

Epyc
Name: epiphycan
Synonyms: PG-Lb, epiphycan, SLRR3B, Dspg3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13516
HGNC: HGNC:3053
Homologene: 3634
Itk
Name: IL2 inducible T cell kinase
Synonyms: Emt, Tsk, Tcsk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16428
HGNC: HGNC:6171
Homologene: 4051
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Prrc2b
Name: proline-rich coiled-coil 2B
Synonyms: 5830434P21Rik, Bat2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227723
Homologene: 106649
Col18a1
Name: collagen, type XVIII, alpha 1
Synonyms: endostatin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12822
HGNC: HGNC:2195
Homologene: 7673
Pcm1
Name: pericentriolar material 1
Synonyms: 9430077F19Rik, 2600002H09Rik, C030044G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Kif20a
Name: kinesin family member 20A
Synonyms: Rabkinesin-6, Rab6kifl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 19348
VEGA: 18
HGNC: HGNC:9787
Homologene: 38093
Pik3c2a
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
Synonyms: PI3KC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18704
HGNC: HGNC:8971
Homologene: 20581
Senp6
Name: SUMO/sentrin specific peptidase 6
Synonyms: 2810017C20Rik, E130319N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 215351
Homologene: 9196
Urb2
Name: URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382038
Homologene: 8859
Ahctf1
Name: AT hook containing transcription factor 1
Synonyms: 6230412P20Rik, Elys
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226747
Homologene: 9142
Dlgap5
Name: DLG associated protein 5
Synonyms: Hurp, C86398, Dlg7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218977
Homologene: 8840
Dmtf1
Name: cyclin D binding myb like transcription factor 1
Synonyms: Dmp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 23857
Homologene: 8017
Tanc2
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Synonyms: 5730590C14Rik, 3526402J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 77097
Homologene: 64680
Adcy4
Name: adenylate cyclase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 104110
VEGA: 14
HGNC: HGNC:235
Homologene: 23149
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: A930005E13Rik, LOC381562, D930005K06Rik, 1810009A16Rik, Zubr1, p600
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69116
Homologene: 10804
Adam30
Name: a disintegrin and metallopeptidase domain 30
Synonyms: 4933424D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71078
HGNC: HGNC:208
Homologene: 11038
Atp13a5
Name: ATPase type 13A5
Synonyms: C630015F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268878
Homologene: 77451
Cdan1
Name: congenital dyserythropoietic anemia, type I (human)
Synonyms: CDA-I, CDA1, 1500015A01Rik, codanin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68968
HGNC: HGNC:1713
Homologene: 16324
Fchsd1
Name: FCH and double SH3 domains 1
Synonyms: A030002D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 319262
Homologene: 14127
Olfm3
Name: olfactomedin 3
Synonyms: optimedin, B230206G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229759
Homologene: 17103
Glg1
Name: golgi apparatus protein 1
Synonyms: ESL-1, CFR, MG-160, MG160, CFR-1, Selel
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20340
HGNC: HGNC:4316
Homologene: 7533
Foxk1
Name: forkhead box K1
Synonyms: Mnf, A630048H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17425
Homologene: 82414
Katnip
Name: katanin interacting protein
Synonyms: D430042O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233865
Homologene: 45841
Cnbd1
Name: cyclic nucleotide binding domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 435772
Homologene: 27843
Klhl14
Name: kelch-like 14
Synonyms: 6330403N15Rik, printor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225266
Homologene: 28121
Fam135b
Name: family with sequence similarity 135, member B
Synonyms: A830008O07Rik, 1700010C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70363
VEGA: 15
Homologene: 66605
Strc
Name: stereocilin
Synonyms: DFNB16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 140476
Homologene: 15401
Camk2d
Name: calcium/calmodulin-dependent protein kinase II, delta
Synonyms: CaMK II, 2810011D23Rik, 8030469K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 108058
HGNC: HGNC:1462
Homologene: 55561
Cma1
Name: chymase 1, mast cell
Synonyms: MMCP-5, Mcp-5, Mcpt5, Mcp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 17228
VEGA: 14
HGNC: HGNC:2097
Homologene: 55606
Pcsk6
Name: proprotein convertase subtilisin/kexin type 6
Synonyms: PACE4, SPC4, b2b2830Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18553
HGNC: HGNC:8569
Homologene: 20569
Ablim1
Name: actin-binding LIM protein 1
Synonyms: Limab1, 4833406P10Rik, abLIM-S, abLIM-M, abLIM-L, 2610209L21Rik, 9330196J19Rik, 2210411C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226251
HGNC: HGNC:78
Homologene: 40994
Thsd7a
Name: thrombospondin, type I, domain containing 7A
Synonyms: LOC330267
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330267
Homologene: 46582
Tlr11
Name: toll-like receptor 11
Synonyms: LOC239081
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239081
Homologene: 77905
Pitpnm3
Name: PITPNM family member 3
Synonyms: A330068P14Rik, Ackr6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327958
Homologene: 66271
Adck1
Name: aarF domain containing kinase 1
Synonyms: 2610005A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 72113
VEGA: 12
Homologene: 6493
Vmn2r27
Name: vomeronasal 2, receptor27
Synonyms: EG232367
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232367
Ugt1a6a
Name: UDP glucuronosyltransferase 1 family, polypeptide A6A
Synonyms: UGT1.6, Ugt1a6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 94284
Homologene: 85959
Cpb2
Name: carboxypeptidase B2 (plasma)
Synonyms: thrombin-activatable fibrinolysis inhibitor, CPU, carboxypeptidase U, TAFI, 1110032P04Rik, carboxypeptidase R, CPR, 4930405E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 56373
VEGA: 14
HGNC: HGNC:2300
Homologene: 55610
Vmn2r16
Name: vomeronasal 2, receptor 16
Synonyms: EG384220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 384220
Homologene: 104825
Spag6l
Name: sperm associated antigen 6-like
Synonyms: PF16, Spag6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 50525
Homologene: 8252
Meioc
Name: meiosis specific with coiled-coil domain
Synonyms: LOC380729, LOC268491, Gm1564
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268491
Homologene: 19559
Or5b24
Name: olfactory receptor family 5 subfamily B member 24
Synonyms: GA_x6K02T2RE5P-3264213-3265157, MOR202-34, Olfr1449
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258300
Homologene: 17184
Cel
Name: carboxyl ester lipase
Synonyms: BAL, 1810036E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12613
HGNC: HGNC:1848
Homologene: 37529
Hdac9
Name: histone deacetylase 9
Synonyms: HDRP, Hdac7b, Mitr, D030072B18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 79221
Homologene: 128578
Ttll10
Name: tubulin tyrosine ligase-like family, member 10
Synonyms: 4930595O22Rik, 4833412E22Rik, Ttll5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 330010
Homologene: 51912
Slc22a22
Name: solute carrier family 22 (organic cation transporter), member 22
Synonyms: OAT-PG, BC026439
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 210463
Homologene: 18166
Pctp
Name: phosphatidylcholine transfer protein
Synonyms: PC-TP, StarD2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18559
HGNC: HGNC:8752
Homologene: 32054
Dagla
Name: diacylglycerol lipase, alpha
Synonyms: Nsddr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 269060
HGNC: HGNC:1165
Homologene: 4468
Apold1
Name: apolipoprotein L domain containing 1
Synonyms: LOC381823
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 381823
Homologene: 12781
Ift57
Name: intraflagellar transport 57
Synonyms: MHS4R2, HIPPI, 4833420A15Rik, Esrrbl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 73916
Homologene: 32383
Utp14b
Name: UTP14B small subunit processome component
Synonyms: jsd, 4932411L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 195434
Homologene: 78703
Klhdc3
Name: kelch domain containing 3
Synonyms: 1300011D16Rik, Peas
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 71765
VEGA: 17
Homologene: 14290
Rad18
Name: RAD18 E3 ubiquitin protein ligase
Synonyms: 2810024C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 58186
Homologene: 48572
Thap11
Name: THAP domain containing 11
Synonyms: CTG-B45d, Ronin, 2810036E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 59016
Homologene: 10726
Ccin
Name: calicin
Synonyms: 4933417A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 442829
HGNC: HGNC:1568
Homologene: 4306
Sox15
Name: SRY (sex determining region Y)-box 15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20670
Homologene: 74586
Fuom
Name: fucose mutarotase
Synonyms: 1810014F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69064
Homologene: 19598
Homez
Name: homeodomain leucine zipper-encoding gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239099
Homologene: 10828
Ifit3b
Name: interferon-induced protein with tetratricopeptide repeats 3B
Synonyms: I830012O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 667370
HGNC: HGNC:5411
Homologene: 1189
Gm13199
Name: predicted gene 13199
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 791411
Ap1s3
Name: adaptor-related protein complex AP-1, sigma 3
Synonyms: [s]3A, Jr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 252903
Homologene: 65622
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 34,186,050 bp
  • A to T, chromosome 1 at 78,664,942 bp
  • A to T, chromosome 1 at 78,664,943 bp
  • G to T, chromosome 1 at 79,614,243 bp
  • C to T, chromosome 1 at 88,215,788 bp
  • A to G, chromosome 1 at 179,746,542 bp
  • C to T, chromosome 2 at 5,862,254 bp
  • T to A, chromosome 2 at 28,560,945 bp
  • A to G, chromosome 2 at 32,212,080 bp
  • T to C, chromosome 2 at 120,723,902 bp
  • T to C, chromosome 2 at 121,376,922 bp
  • A to G, chromosome 3 at 98,161,964 bp
  • G to A, chromosome 3 at 115,122,306 bp
  • T to G, chromosome 3 at 126,779,865 bp
  • T to C, chromosome 4 at 18,862,056 bp
  • A to G, chromosome 4 at 43,983,854 bp
  • A to T, chromosome 4 at 139,455,638 bp
  • T to C, chromosome 4 at 156,036,066 bp
  • T to A, chromosome 5 at 9,122,415 bp
  • T to A, chromosome 5 at 109,362,287 bp
  • T to C, chromosome 5 at 142,456,674 bp
  • T to A, chromosome 6 at 12,337,262 bp
  • T to C, chromosome 6 at 112,696,642 bp
  • T to A, chromosome 6 at 124,231,727 bp
  • C to T, chromosome 6 at 134,983,723 bp
  • A to G, chromosome 7 at 66,043,611 bp
  • A to G, chromosome 7 at 116,362,564 bp
  • A to G, chromosome 7 at 125,813,635 bp
  • A to T, chromosome 7 at 140,099,898 bp
  • T to C, chromosome 8 at 41,328,979 bp
  • A to G, chromosome 8 at 105,856,064 bp
  • G to T, chromosome 8 at 111,259,104 bp
  • T to C, chromosome 8 at 124,029,659 bp
  • T to C, chromosome 9 at 80,142,294 bp
  • T to A, chromosome 10 at 77,096,397 bp
  • A to T, chromosome 10 at 97,649,842 bp
  • A to T, chromosome 11 at 46,344,855 bp
  • C to T, chromosome 11 at 69,655,730 bp
  • G to T, chromosome 11 at 72,112,367 bp
  • A to G, chromosome 11 at 89,986,119 bp
  • A to T, chromosome 11 at 102,675,153 bp
  • A to G, chromosome 11 at 105,840,625 bp
  • G to T, chromosome 12 at 34,373,883 bp
  • A to G, chromosome 12 at 88,459,052 bp
  • T to A, chromosome 14 at 47,413,754 bp
  • T to G, chromosome 14 at 50,360,777 bp
  • C to T, chromosome 14 at 54,856,841 bp
  • T to C, chromosome 14 at 55,779,099 bp
  • A to C, chromosome 14 at 55,941,656 bp
  • T to C, chromosome 14 at 75,283,387 bp
  • C to T, chromosome 15 at 57,263,536 bp
  • A to G, chromosome 15 at 71,462,895 bp
  • C to A, chromosome 16 at 16,763,021 bp
  • T to C, chromosome 16 at 29,339,042 bp
  • C to T, chromosome 16 at 49,711,108 bp
  • A to T, chromosome 17 at 46,675,102 bp
  • A to G, chromosome 18 at 21,565,535 bp
  • G to A, chromosome 18 at 34,632,415 bp
  • C to T, chromosome 18 at 37,959,873 bp
  • T to C, chromosome 19 at 10,248,424 bp
  • T to C, chromosome 19 at 12,935,047 bp
  • A to G, chromosome 19 at 34,611,742 bp
  • T to C, chromosome 19 at 57,041,935 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5958 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044145-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.