Strain Name:
C57BL/6J-MtgxR6007Btlr
Stock Number:
044184-MU
Citation ID:
RRID:MMRRC_044184-MU
Other Names:
R6007 (G1)
Major Collection:

Gene Information

Secisbp2
Name: SECIS binding protein 2
Synonyms: 2210413N07Rik, SBP2, 2810012K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75420
Homologene: 11415
Crybg3
Name: beta-gamma crystallin domain containing 3
Synonyms: Gm9581
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224273
Homologene: 28544
Ylpm1
Name: YLP motif containing 1
Synonyms: ZAP, Zap3, A930013E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56531
Homologene: 87707
Phf3
Name: PHD finger protein 3
Synonyms: 2310061N19Rik, AU020177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213109
HGNC: HGNC:8921
Homologene: 9040
Larp4b
Name: La ribonucleoprotein domain family, member 4B
Synonyms: D13Wsu64e, Larp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 217980
Homologene: 18195
Ints8
Name: integrator complex subunit 8
Synonyms: D130008D20Rik, 2810013E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72656
Homologene: 9888
Orc2
Name: origin recognition complex, subunit 2
Synonyms: Orc2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18393
HGNC: HGNC:8488
Homologene: 4512
Abcg5
Name: ATP binding cassette subfamily G member 5
Synonyms: Sterolin-1, trac, cmp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 27409
Homologene: 31909
Mc5r
Name: melanocortin 5 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17203
VEGA: 18
HGNC: HGNC:6933
Homologene: 4321
Zfyve1
Name: zinc finger, FYVE domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217695
VEGA: 12
Homologene: 10945
Trp53bp2
Name: transformation related protein 53 binding protein 2
Synonyms: ASPP2, 53BP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 209456
Homologene: 3959
Drg2
Name: developmentally regulated GTP binding protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13495
HGNC: HGNC:3030
Homologene: 1061
Unc5b
Name: unc-5 netrin receptor B
Synonyms: 6330415E02Rik, Unc5h2, D10Bwg0792e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 107449
VEGA: 10
Homologene: 32538
Gm14496
Name: predicted gene 14496
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 672125
Homologene: 129606
Gpc6
Name: glypican 6
Synonyms: 6720429C22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 23888
HGNC: HGNC:4454
Homologene: 55922
Mme
Name: membrane metallo endopeptidase
Synonyms: CD10, neprilysin, 6030454K05Rik, NEP, neutral endopeptidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 17380
HGNC: HGNC:7154
Homologene: 5275
Ddx20
Name: DEAD box helicase 20
Synonyms: GEMIN3, dp103, DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 53975
HGNC: HGNC:2743
Homologene: 5214
Wdr18
Name: WD repeat domain 18
Synonyms: 2310012I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216156
VEGA: 10
Homologene: 32573
Flcn
Name: folliculin
Synonyms: B430214A04Rik, BHD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216805
Homologene: 14583
Mslnl
Name: mesothelin-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 328783
VEGA: 17
Homologene: 18633
Adgrf5
Name: adhesion G protein-coupled receptor F5
Synonyms: 8430401C09Rik, Gpr116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224792
VEGA: 17
Homologene: 9065
Rapgef4
Name: Rap guanine nucleotide exchange factor (GEF) 4
Synonyms: Epac2, cAMP-GEFII, 1300003D15Rik, 5730402K07Rik, 6330581N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56508
Homologene: 4451
Fstl5
Name: follistatin-like 5
Synonyms: 9130207J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213262
Homologene: 10584
Tmem116
Name: transmembrane protein 116
Synonyms: 4930513P12Rik, 4930406A18Rik, C030022K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 77462
Homologene: 12676
Gpr179
Name: G protein-coupled receptor 179
Synonyms: 5330439C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217143
Homologene: 34917
4930407I10Rik
Name: RIKEN cDNA 4930407I10 gene
Synonyms: LOC328573
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 328573
VEGA: 15
Homologene: 130065
Olfr736
Name: olfactory receptor 736
Synonyms: GA_x6K02T2PMLR-6089963-6090901, MOR106-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258660
Homologene: 64902
Chd5
Name: chromodomain helicase DNA binding protein 5
Synonyms: B230399N07Rik, 4930532L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269610
Homologene: 56712
Npepl1
Name: aminopeptidase-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228961
Homologene: 11647
Slc4a10
Name: solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
Synonyms: NCBE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94229
Homologene: 23340
Map3k13
Name: mitogen-activated protein kinase kinase kinase 13
Synonyms: C130026N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 71751
VEGA: 16
HGNC: HGNC:6852
Homologene: 37958
Top2b
Name: topoisomerase (DNA) II beta
Synonyms: Top-2, D230016L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21974
Homologene: 134711
Vil1
Name: villin 1
Synonyms: Villin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22349
Homologene: 5169
Bpifb4
Name: BPI fold containing family B, member 4
Synonyms: LOC381399, Gm1006
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381399
Homologene: 66971
1700003E16Rik
Name: RIKEN cDNA 1700003E16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71837
Homologene: 52846
Iqsec1
Name: IQ motif and Sec7 domain 1
Synonyms: cI-43, D6Ertd349e, BRAG2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232227
Homologene: 82429
Nrg3
Name: neuregulin 3
Synonyms: ska
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18183
HGNC: HGNC:7999
Homologene: 32051
Plxnc1
Name: plexin C1
Synonyms: vespr, 2510048K12Rik, CD232
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 54712
HGNC: HGNC:9106
Homologene: 4211
Rnf180
Name: ring finger protein 180
Synonyms: 3110001E11Rik, Rines
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 71816
VEGA: 13
Homologene: 18677
Vmn2r107
Name: vomeronasal 2, receptor 107
Synonyms: V2r6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22312
Homologene: 129750
A830018L16Rik
Name: RIKEN cDNA A830018L16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 320492
Homologene: 14194
Chml
Name: choroideremia-like
Synonyms: Rep2, E030003F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12663
HGNC: HGNC:1941
Homologene: 31055
Vmn2r86
Name: vomeronasal 2, receptor 86
Synonyms: EG625109
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 625109
Homologene: 129606
Zfp647
Name: zinc finger protein 647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239546
VEGA: 15
Homologene: 27805
Synpo
Name: synaptopodin
Synonyms: 9330140I15Rik, 9030217H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 104027
Homologene: 5274
Arl8a
Name: ADP-ribosylation factor-like 8A
Synonyms: 1110033P22Rik, Arl10b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68724
Homologene: 23600
Olfr1275
Name: olfactory receptor 1275
Synonyms: GA_x6K02T2Q125-72283260-72282322, MOR245-18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257980
Homologene: 79419
Cyp2c68
Name: cytochrome P450, family 2, subfamily c, polypeptide 68
Synonyms: 9030012A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 433247
Homologene: 74936
Amh
Name: anti-Mullerian hormone
Synonyms: MIS, Mullerian inhibiting substance
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11705
VEGA: 10
HGNC: HGNC:464
Homologene: 68060
Zfp677
Name: zinc finger protein 677
Synonyms: A830058L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 210503
Homologene: 138402
Sertad2
Name: SERTA domain containing 2
Synonyms: Trip-Br2, Sei2, SEI-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 58172
Homologene: 8843
Mrpl24
Name: mitochondrial ribosomal protein L24
Synonyms: 2810470K06Rik, 6720473G22Rik, 2010005E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67707
Homologene: 12241
Dchs2
Name: dachsous cadherin related 2
Synonyms: LOC229459
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 100534287
Gm43772
Name: predicted gene 43772
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 108169122
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 11,511,916 bp
  • A to T, chromosome 1 at 30,804,345 bp
  • A to T, chromosome 1 at 58,467,692 bp
  • T to C, chromosome 1 at 74,419,867 bp
  • T to C, chromosome 1 at 135,152,868 bp
  • A to G, chromosome 1 at 175,688,028 bp
  • T to A, chromosome 1 at 182,455,740 bp
  • A to G, chromosome 2 at 62,268,872 bp
  • T to C, chromosome 2 at 72,179,949 bp
  • T to C, chromosome 2 at 111,230,930 bp
  • T to C, chromosome 2 at 153,942,560 bp
  • T to C, chromosome 2 at 174,121,057 bp
  • A to G, chromosome 2 at 181,997,530 bp
  • G to A, chromosome 3 at 63,343,508 bp
  • T to A, chromosome 3 at 76,410,592 bp
  • G to T, chromosome 3 at 83,346,227 bp
  • A to G, chromosome 3 at 87,922,398 bp
  • T to C, chromosome 3 at 105,683,420 bp
  • G to A, chromosome 4 at 11,208,845 bp
  • A to T, chromosome 4 at 152,379,421 bp
  • T to C, chromosome 5 at 66,174,991 bp
  • A to C, chromosome 5 at 121,517,892 bp
  • G to T, chromosome 6 at 83,160,918 bp
  • G to T, chromosome 6 at 90,660,987 bp
  • A to G, chromosome 10 at 60,765,360 bp
  • A to G, chromosome 10 at 79,965,343 bp
  • A to G, chromosome 10 at 80,805,471 bp
  • T to C, chromosome 10 at 94,793,290 bp
  • T to C, chromosome 10 at 130,453,666 bp
  • G to A, chromosome 11 at 20,647,884 bp
  • C to A, chromosome 11 at 59,792,622 bp
  • T to C, chromosome 11 at 60,462,625 bp
  • A to T, chromosome 11 at 97,335,802 bp
  • A to G, chromosome 12 at 83,558,704 bp
  • A to G, chromosome 12 at 85,029,290 bp
  • T to C, chromosome 13 at 9,168,757 bp
  • T to C, chromosome 13 at 51,665,359 bp
  • C to A, chromosome 13 at 105,181,449 bp
  • G to A, chromosome 14 at 16,423,779 bp
  • T to A, chromosome 14 at 39,472,452 bp
  • G to T, chromosome 14 at 50,393,491 bp
  • C to T, chromosome 14 at 117,951,261 bp
  • G to A, chromosome 15 at 76,912,085 bp
  • C to G, chromosome 15 at 82,062,739 bp
  • A to T, chromosome 16 at 21,905,183 bp
  • G to T, chromosome 16 at 59,554,474 bp
  • A to T, chromosome 17 at 20,375,054 bp
  • A to G, chromosome 17 at 21,397,656 bp
  • G to A, chromosome 17 at 25,746,775 bp
  • T to A, chromosome 17 at 43,437,571 bp
  • T to G, chromosome 17 at 84,668,964 bp
  • T to A, chromosome 18 at 60,603,615 bp
  • A to T, chromosome 18 at 68,339,247 bp
  • T to C, chromosome 19 at 39,734,336 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
(Deceased) Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6007 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044184-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.