Strain Name:
C57BL/6J-MtgxR6009Btlr
Stock Number:
044186-MU
Citation ID:
RRID:MMRRC_044186-MU
Other Names:
R6009 (G1)
Major Collection:

Gene Information

Setd5
Name: SET domain containing 5
Synonyms: 2900045N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 72895
Homologene: 12485
Dgka
Name: diacylglycerol kinase, alpha
Synonyms: Dagk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13139
VEGA: 10
HGNC: HGNC:2849
Homologene: 1028
Ctdspl2
Name: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
Synonyms: SCP4, D2Ertd485e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 329506
Homologene: 32311
Slc25a26
Name: solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26
Synonyms: 4930433D19Rik, 4933433F13Rik, D6Bwg0781e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67582
Homologene: 6834
Gtf3c1
Name: general transcription factor III C 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233863
HGNC: HGNC:4664
Homologene: 31040
Ints9
Name: integrator complex subunit 9
Synonyms: D14Ertd231e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 210925
VEGA: 14
Homologene: 10096
Rnf169
Name: ring finger protein 169
Synonyms: 2900057K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 108937
Homologene: 47510
Smchd1
Name: SMC hinge domain containing 1
Synonyms: MommeD1, 4931400A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 74355
Homologene: 23665
Parn
Name: poly(A)-specific ribonuclease (deadenylation nuclease)
Synonyms: 1200003I18Rik, DAN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 74108
VEGA: 16
HGNC: HGNC:8609
Homologene: 31098
Actr8
Name: ARP8 actin-related protein 8
Synonyms: ARP8, 5730542K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 56249
VEGA: 14
Homologene: 11286
Dbf4
Name: DBF4 zinc finger
Synonyms: Ask
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 27214
Homologene: 40892
Polr3c
Name: polymerase (RNA) III (DNA directed) polypeptide C
Synonyms: RPC3, RPC62, 4933407E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74414
Homologene: 38185
Afap1
Name: actin filament associated protein 1
Synonyms: 2600003E23Rik, 9630044L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70292
Homologene: 11009
Polr2b
Name: polymerase (RNA) II (DNA directed) polypeptide B
Synonyms: RPB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231329
HGNC: HGNC:9188
Homologene: 722
Flii
Name: flightless I actin binding protein
Synonyms: Fliih, 3632430F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14248
HGNC: HGNC:3750
Homologene: 11092
Il17f
Name: interleukin 17F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 257630
Homologene: 17115
Pdgfa
Name: platelet derived growth factor, alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18590
HGNC: HGNC:8799
Homologene: 32055
Vav2
Name: vav 2 oncogene
Synonyms: 2810040F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22325
Homologene: 2530
Npat
Name: nuclear protein in the AT region
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244879
HGNC: HGNC:7896
Homologene: 1888
Gtpbp1
Name: GTP binding protein 1
Synonyms: GTPBP1, GP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 14904
VEGA: 15
HGNC: HGNC:4669
Homologene: 3165
Nus1
Name: NUS1 dehydrodolichyl diphosphate synthase subunit
Synonyms: D10Ertd438e, 1600027K07Rik, NgBR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 52014
Homologene: 12719
Dazap1
Name: DAZ associated protein 1
Synonyms: 2410042M16Rik, mPrrp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70248
HGNC: HGNC:2683
Homologene: 134440
Pprc1
Name: peroxisome proliferative activated receptor, gamma, coactivator-related 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226169
Homologene: 9006
Fnip1
Name: folliculin interacting protein 1
Synonyms: A730024A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216742
Homologene: 28173
Fam13b
Name: family with sequence similarity 13, member B
Synonyms: 2610024E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225358
VEGA: 18
HGNC: HGNC:1335
Homologene: 9585
Zfp345
Name: zinc finger protein 345
Synonyms: OTTMUSG00000015743
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 545471
Homologene: 134546
Lemd1
Name: LEM domain containing 1
Synonyms: 4930540I23Rik, LEMP-1, 6430514M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 213409
Gstm4
Name: glutathione S-transferase, mu 4
Synonyms: Gstb4, 1110004G14Rik, Gstb-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 14865
HGNC: HGNC:4636
Homologene: 37357
Maml2
Name: mastermind like transcriptional coactivator 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270118
Homologene: 134147
Ttll7
Name: tubulin tyrosine ligase-like family, member 7
Synonyms: 1110049N09Rik, 4921517B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 70892
Homologene: 41578
Hoxa7
Name: homeobox A7
Synonyms: Hox-1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 15404
HGNC: HGNC:5108
Homologene: 56001
Kctd7
Name: potassium channel tetramerisation domain containing 7
Synonyms: 9430010P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 212919
Homologene: 17687
Gm7247
Name: predicted gene 7247
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 638695
Gtf3c5
Name: general transcription factor IIIC, polypeptide 5
Synonyms: TFIIICepsilon, 2700084A09Rik, TFIIIC63, TFiiiC2-63
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 70239
HGNC: HGNC:4668
Homologene: 40806
Plcl1
Name: phospholipase C-like 1
Synonyms: PRIP-1, PLC-L, C230017K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227120
HGNC: HGNC:9063
Homologene: 38155
Kansl1l
Name: KAT8 regulatory NSL complex subunit 1-like
Synonyms: C430010P07Rik, 1110028C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68691
Homologene: 27376
Golgb1
Name: golgi autoantigen, golgin subfamily b, macrogolgin 1
Synonyms: 6330407A06Rik, Giantin, F730017E11Rik, C130074L01Rik, Gm6840
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224139
HGNC: HGNC:4429
Homologene: 68401
Slc4a10
Name: solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
Synonyms: NCBE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 94229
Homologene: 23340
Mtus2
Name: microtubule associated tumor suppressor candidate 2
Synonyms: 5730592G18Rik, C130038G02Rik, A730013O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 77521
Homologene: 78141
Zfp651
Name: zinc finger protein 651
Synonyms: 4732420M22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270210
VEGA: 9
Homologene: 136302
Prex1
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Synonyms: P-REX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 277360
Homologene: 10821
Mief2
Name: mitochondrial elongation factor 2
Synonyms: Smcr7, LOC237781
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237781
Homologene: 27354
Naaa
Name: N-acylethanolamine acid amidase
Synonyms: Asahl, 3830414F09Rik, 2210023K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 67111
HGNC: HGNC:736
Homologene: 8686
Krt82
Name: keratin 82
Synonyms: Krt2-20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 114566
VEGA: 15
HGNC: HGNC:6459
Homologene: 13200
Crlf1
Name: cytokine receptor-like factor 1
Synonyms: cytokine receptor like molecule 3, CRLM3, CLF-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12931
HGNC: HGNC:2364
Homologene: 3489
Zfp964
Name: zinc finger protein 964
Synonyms: Gm7187
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 636741
Homologene: 130114
Nek5
Name: NIMA (never in mitosis gene a)-related expressed kinase 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 330721
HGNC: HGNC:7748
Homologene: 87952
Msantd1
Name: Myb/SANT-like DNA-binding domain containing 1
Synonyms: LOC231132, A930005I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 403174
Homologene: 45807
Cyb561a3
Name: cytochrome b561 family, member A3
Synonyms: 2310004G04Rik, Cybasc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225912
VEGA: 19
Homologene: 15558
Clstn2
Name: calsyntenin 2
Synonyms: CS2, Cst-2, CSTN2, 2900042C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 64085
Homologene: 49698
Chid1
Name: chitinase domain containing 1
Synonyms: 3110023E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68038
Homologene: 12229
Plscr5
Name: phospholipid scramblase family, member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 100504689
Homologene: 28688
Olfr550
Name: olfactory receptor 550
Synonyms: MOR16-1, GA_x6K02T2PBJ9-5297243-5298193
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259108
Homologene: 17507
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 20,779,286 bp
  • T to A, chromosome 1 at 55,696,246 bp
  • C to T, chromosome 1 at 66,735,600 bp
  • G to T, chromosome 1 at 132,228,252 bp
  • A to T, chromosome 2 at 27,271,900 bp
  • A to T, chromosome 2 at 28,571,165 bp
  • A to G, chromosome 2 at 62,046,690 bp
  • T to G, chromosome 2 at 121,988,838 bp
  • A to T, chromosome 2 at 150,472,517 bp
  • C to T, chromosome 2 at 166,581,984 bp
  • A to G, chromosome 3 at 96,713,614 bp
  • A to G, chromosome 3 at 108,043,343 bp
  • A to T, chromosome 3 at 146,934,535 bp
  • G to T, chromosome 5 at 8,403,718 bp
  • C to A, chromosome 5 at 34,917,705 bp
  • T to C, chromosome 5 at 35,997,560 bp
  • T to C, chromosome 5 at 77,320,252 bp
  • A to T, chromosome 5 at 92,259,581 bp
  • G to A, chromosome 5 at 130,145,198 bp
  • T to C, chromosome 5 at 138,979,199 bp
  • A to G, chromosome 5 at 148,306,652 bp
  • C to T, chromosome 6 at 52,217,387 bp
  • G to T, chromosome 6 at 94,510,826 bp
  • A to G, chromosome 6 at 113,110,519 bp
  • C to A, chromosome 7 at 99,927,123 bp
  • A to G, chromosome 7 at 102,578,594 bp
  • A to G, chromosome 7 at 125,647,430 bp
  • T to A, chromosome 7 at 141,529,580 bp
  • T to C, chromosome 8 at 22,120,822 bp
  • T to A, chromosome 8 at 69,663,456 bp
  • A to C, chromosome 8 at 70,503,479 bp
  • A to G, chromosome 9 at 13,620,998 bp
  • T to C, chromosome 9 at 53,563,449 bp
  • C to T, chromosome 9 at 92,204,435 bp
  • C to T, chromosome 9 at 97,456,526 bp
  • T to C, chromosome 9 at 121,762,871 bp
  • G to A, chromosome 10 at 52,433,443 bp
  • T to C, chromosome 10 at 80,285,304 bp
  • C to T, chromosome 10 at 128,723,679 bp
  • G to T, chromosome 11 at 54,502,271 bp
  • A to T, chromosome 11 at 60,720,757 bp
  • A to G, chromosome 11 at 60,731,659 bp
  • A to G, chromosome 14 at 29,978,497 bp
  • C to T, chromosome 14 at 51,364,348 bp
  • T to C, chromosome 14 at 65,008,082 bp
  • G to A, chromosome 15 at 79,712,096 bp
  • T to A, chromosome 15 at 101,545,105 bp
  • C to T, chromosome 16 at 13,667,564 bp
  • G to T, chromosome 16 at 36,914,959 bp
  • A to T, chromosome 17 at 71,440,956 bp
  • A to T, chromosome 18 at 34,497,405 bp
  • G to A, chromosome 19 at 10,586,808 bp
  • A to T, chromosome 19 at 46,071,732 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6009 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044186-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.