Strain Name:
C57BL/6J-MtgxR6038Btlr
Stock Number:
044208-MU
Citation ID:
RRID:MMRRC_044208-MU
Other Names:
R6038 (G1)
Major Collection:

Gene Information

Gene Symbol: Epha7 [MGI:95276] (Mus musculus (mouse))
Name: Eph receptor A7
Synonyms: Mdk1, Ebk, Hek11, Cek11, Ehk3, MDK1
Chromosome: 4
Alteration at locus: Chemically Induced
Gene Symbol: Epb41l4a [MGI:103007] (Mus musculus (mouse))
Name: erythrocyte membrane protein band 4.1 like 4a
Synonyms: NBL4, Epb4.1l4a
Chromosome: 18
Alteration at locus: Chemically Induced
Gene Symbol: Pnmt [MGI:97724] (Mus musculus (mouse))
Name: phenylethanolamine-N-methyltransferase
Synonyms: Pent
Chromosome: 11
Alteration at locus: Chemically Induced
Gene Symbol: Smarcad1 [MGI:95453] (Mus musculus (mouse))
Name: SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
Synonyms: D6Pas1, Etl1
Chromosome: 6
Alteration at locus: Chemically Induced
Gene Symbol: Cabin1 [MGI:1298375] (Mus musculus (mouse))
Name: calcineurin binding protein 1
Synonyms: Cain, Ppp3in, A330070M20Rik
Chromosome: 10
Alteration at locus: Chemically Induced
Gene Symbol: Larp1 [MGI:1890165] (Mus musculus (mouse))
Name: La ribonucleoprotein domain family, member 1
Synonyms: 1810024J12Rik, Larp, 3110040D16Rik
Chromosome: 11
Alteration at locus: Chemically Induced
Gene Symbol: Coro7 [MGI:1926135] (Mus musculus (mouse))
Name: coronin 7
Synonyms: 0610011B16Rik
Chromosome: 16
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 75,418,459 bp
  • A to G, chromosome 1 at 120,241,641 bp
  • C to T, chromosome 1 at 191,162,722 bp
  • G to C, chromosome 2 at 14,257,071 bp
  • T to A, chromosome 2 at 87,269,267 bp
  • A to G, chromosome 2 at 125,085,731 bp
  • T to G, chromosome 2 at 152,576,267 bp
  • G to A, chromosome 4 at 28,821,521 bp
  • G to C, chromosome 4 at 43,555,052 bp
  • A to G, chromosome 4 at 123,750,163 bp
  • A to G, chromosome 4 at 141,464,441 bp
  • A to T, chromosome 5 at 44,001,793 bp
  • A to T, chromosome 5 at 49,999,145 bp
  • A to T, chromosome 5 at 117,284,105 bp
  • T to C, chromosome 6 at 8,013,140 bp
  • T to C, chromosome 6 at 65,073,248 bp
  • C to A, chromosome 6 at 87,287,000 bp
  • T to A, chromosome 6 at 100,804,594 bp
  • A to T, chromosome 6 at 131,689,481 bp
  • T to C, chromosome 7 at 4,753,595 bp
  • C to A, chromosome 7 at 42,194,962 bp
  • C to T, chromosome 7 at 44,500,295 bp
  • CT to C, chromosome 7 at 139,923,775 bp
  • A to G, chromosome 8 at 54,632,311 bp
  • A to G, chromosome 8 at 88,322,980 bp
  • T to G, chromosome 8 at 94,330,472 bp
  • A to G, chromosome 8 at 110,599,031 bp
  • A to G, chromosome 9 at 19,783,562 bp
  • A to G, chromosome 10 at 75,739,366 bp
  • T to C, chromosome 11 at 5,524,798 bp
  • T to C, chromosome 11 at 51,620,085 bp
  • A to G, chromosome 11 at 58,041,605 bp
  • C to G, chromosome 11 at 94,112,092 bp
  • C to T, chromosome 11 at 97,050,716 bp
  • G to A, chromosome 11 at 98,387,768 bp
  • G to A, chromosome 11 at 101,184,636 bp
  • T to C, chromosome 11 at 118,055,889 bp
  • A to T, chromosome 12 at 40,733,351 bp
  • A to G, chromosome 12 at 54,181,690 bp
  • A to T, chromosome 12 at 66,630,053 bp
  • G to A, chromosome 12 at 74,222,535 bp
  • C to T, chromosome 12 at 75,878,384 bp
  • A to T, chromosome 12 at 103,946,836 bp
  • T to C, chromosome 12 at 105,202,507 bp
  • G to T, chromosome 13 at 6,597,969 bp
  • G to T, chromosome 13 at 14,346,062 bp
  • T to C, chromosome 13 at 55,006,560 bp
  • A to T, chromosome 13 at 112,891,290 bp
  • G to A, chromosome 13 at 113,318,619 bp
  • T to C, chromosome 14 at 47,263,580 bp
  • T to C, chromosome 14 at 50,486,220 bp
  • T to C, chromosome 14 at 75,031,970 bp
  • A to C, chromosome 15 at 39,872,380 bp
  • A to T, chromosome 16 at 4,679,550 bp
  • A to T, chromosome 16 at 5,102,581 bp
  • C to T, chromosome 16 at 22,932,331 bp
  • A to T, chromosome 17 at 5,336,682 bp
  • T to C, chromosome 17 at 25,246,334 bp
  • T to C, chromosome 17 at 35,861,505 bp
  • C to A, chromosome 17 at 36,368,395 bp
  • T to C, chromosome 17 at 43,295,209 bp
  • A to G, chromosome 17 at 46,304,360 bp
  • T to A, chromosome 18 at 31,680,486 bp
  • T to C, chromosome 18 at 33,854,335 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6038 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044208-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials and based on the transfer success rate of the MMRRC facility) to transfer to at least two recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.