Strain Name:
C57BL/6J-MtgxR6044Btlr
Stock Number:
044212-MU
Citation ID:
RRID:MMRRC_044212-MU
Other Names:
R6044 (G1)
Major Collection:

Gene Information

Adamts20
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
Synonyms: bt, ADAMTS-20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223838
Homologene: 11808
Wrn
Name: Werner syndrome RecQ like helicase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 22427
Homologene: 6659
Gap43
Name: growth associated protein 43
Synonyms: neuromodulin, B-50, Basp2, GAP-43
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 14432
HGNC: HGNC:4140
Homologene: 1545
Wee1
Name: WEE 1 homolog 1 (S. pombe)
Synonyms: Wee1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22390
Homologene: 31152
Eml4
Name: echinoderm microtubule associated protein like 4
Synonyms: 4930443C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78798
VEGA: 17
HGNC: HGNC:1316
Homologene: 56841
Morc3
Name: microrchidia 3
Synonyms: 1110051N18Rik, Zcwcc3, 1110051N18Rik, D16Jhu32e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 338467
Homologene: 32257
Trpm7
Name: transient receptor potential cation channel, subfamily M, member 7
Synonyms: Ltpr7, 5033407O22Rik, LTRPC7, 4833414K03Rik, TRP-PLIK, CHAK, CHAK1, 2310022G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 58800
Homologene: 9774
Ubr1
Name: ubiquitin protein ligase E3 component n-recognin 1
Synonyms: E3 alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22222
Homologene: 7582
Naa50
Name: N(alpha)-acetyltransferase 50, NatE catalytic subunit
Synonyms: Nat5, Mak3p, 2810441M03Rik, San, 2600005K24Rik, Nat13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 72117
Homologene: 11851
Rab11fip3
Name: RAB11 family interacting protein 3 (class II)
Synonyms: D030060O14Rik, Rab11-FIP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 215445
Homologene: 49396
Amt
Name: aminomethyltransferase
Synonyms: EG434437
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 434437
HGNC: HGNC:473
Homologene: 409
Gprin3
Name: GPRIN family member 3
Synonyms: C030038J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 243385
Homologene: 52334
Bcan
Name: brevican
Synonyms: Cspg7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12032
Homologene: 7244
Tmem131
Name: transmembrane protein 131
Synonyms: Rw1, 2610524E03Rik, CC28, D1Bwg0491e, YR-23, Neg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 56030
Homologene: 32428
Ptprm
Name: protein tyrosine phosphatase, receptor type, M
Synonyms: RPTPmu
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 19274
VEGA: 17
HGNC: HGNC:9675
Homologene: 37694
Adamtsl1
Name: ADAMTS-like 1
Synonyms: punctin-1, 5930437A14Rik, 6720426B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 77739
Homologene: 64642
Crispld2
Name: cysteine-rich secretory protein LCCL domain containing 2
Synonyms: Lgl1, 1810049K24Rik, coffeecrisp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 78892
Homologene: 41792
Mta2
Name: metastasis-associated gene family, member 2
Synonyms: Mta1l1, mmta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 23942
HGNC: HGNC:7411
Homologene: 3480
Foxo1
Name: forkhead box O1
Synonyms: Afxh, Foxo1a, FKHR, Fkhr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 56458
HGNC: HGNC:3819
Homologene: 1527
Gemin4
Name: gem nuclear organelle associated protein 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 276919
Homologene: 69193
Lct
Name: lactase
Synonyms: LPH, Lphl, LOC226413
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226413
HGNC: HGNC:6530
Homologene: 124204
Atp12a
Name: ATPase, H+/K+ transporting, nongastric, alpha polypeptide
Synonyms: Atp1al1, HKalpha2, ATPase H+K+-transporting, alpha 2, cHKA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 192113
VEGA: 14
Homologene: 68197
Dnajc6
Name: DnaJ heat shock protein family (Hsp40) member C6
Synonyms: 2810027M23Rik, auxilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 72685
Homologene: 8865
Tatdn3
Name: TatD DNase domain containing 3
Synonyms: 1500010M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68972
Homologene: 45949
Slc35e2
Name: solute carrier family 35, member E2
Synonyms: A530082C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 320541
Homologene: 84987
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Itpr5, Ip3r2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Agbl1
Name: ATP/GTP binding protein-like 1
Synonyms: EG244071, Nna1-l1, Ccp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244071
Homologene: 17552
Usp40
Name: ubiquitin specific peptidase 40
Synonyms: B230215L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227334
Homologene: 32400
Olfr1395
Name: olfactory receptor 1395
Synonyms: MOR277-1, GA_x6K02T2QP88-6286247-6285294
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258877
Homologene: 105890
Des
Name: desmin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13346
HGNC: HGNC:2770
Homologene: 56469
Slco1a1
Name: solute carrier organic anion transporter family, member 1a1
Synonyms: Oatp1, Slc21a1, Oatp1a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 28248
Homologene: 137261
Mmp12
Name: matrix metallopeptidase 12
Synonyms: Mmel, macrophage elastase, MMP12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17381
HGNC: HGNC:7158
Homologene: 20547
Olfr1250
Name: olfactory receptor 1250
Synonyms: GA_x6K02T2Q125-51098877-51097933, MOR231-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258967
Homologene: 128094
Olfr113
Name: olfactory receptor 113
Synonyms: GA_x6K02T2PSCP-2034880-2033942, MOR218-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258286
Gm973
Name: predicted gene 973
Synonyms: LOC381260
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 381260
Homologene: 124277
Vmn2r27
Name: vomeronasal 2, receptor27
Synonyms: EG232367
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232367
Klri2
Name: killer cell lectin-like receptor family I member 2
Synonyms: A530090P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 320407
Homologene: 86736
Olfr1261
Name: olfactory receptor 1261
Synonyms: MOR234-3, GA_x6K02T2Q125-51425355-51426275
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258466
Homologene: 138310
Alk
Name: anaplastic lymphoma kinase
Synonyms: CD246, Tcrz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 11682
VEGA: 17
HGNC: HGNC:427
Homologene: 68387
Fam186a
Name: family with sequence similarity 186, member A
Synonyms: 1700030F18Rik, LOC380973
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 72277
3425401B19Rik
Name: RIKEN cDNA 3425401B19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 100504518
VEGA: 14
Homologene: 54908
Zfyve16
Name: zinc finger, FYVE domain containing 16
Synonyms: B130024H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218441
Homologene: 8826
Mcm8
Name: minichromosome maintenance 8 homologous recombination repair factor
Synonyms: 5730432L01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66634
Homologene: 12001
Cyp11a1
Name: cytochrome P450, family 11, subfamily a, polypeptide 1
Synonyms: cholesterol side chain cleavage, Scc, P450scc, D9Ertd411e, cscc, Cyp11a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 13070
HGNC: HGNC:2590
Homologene: 37347
Tlcd5
Name: TLC domain containing 5
Synonyms: Tmem136, LOC235300
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235300
VEGA: 9
Homologene: 72560
Padi4
Name: peptidyl arginine deiminase, type IV
Synonyms: Pdi4, PAD type IV, Pad4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18602
Homologene: 7883
Smpdl3a
Name: sphingomyelin phosphodiesterase, acid-like 3A
Synonyms: ASM3A, ASML3A, 0610010C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 57319
Homologene: 4886
Poglut2
Name: protein O-glucosyltransferase 2
Synonyms: EP58, Kdel1, Kdelc1, 5730416C13Rik, 1810049A15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 72050
Homologene: 11367
Olfr1286
Name: olfactory receptor 1286
Synonyms: MOR248-21, GA_x6K02T2Q125-72472405-72471488
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 277562
Homologene: 73992
Hddc3
Name: HD domain containing 3
Synonyms: 1110033O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68695
Homologene: 12279
Prss47
Name: protease, serine 47
Synonyms: LOC218304, Gm274
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218304
Homologene: 28158
Rsph14
Name: radial spoke head homolog 14 (Chlamydomonas)
Synonyms: Rtdr1, 4933431K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71236
Homologene: 49382
Tlcd4
Name: TLC domain containing 4
Synonyms: Tmem56, C730036B01Rik, 4930577M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99887
Homologene: 45107
Sva
Name: seminal vesicle antigen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 20939
BC051628
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 36,881,341 bp
  • A to T, chromosome 1 at 44,114,451 bp
  • T to C, chromosome 1 at 59,628,234 bp
  • A to T, chromosome 1 at 75,363,469 bp
  • A to T, chromosome 1 at 87,990,150 bp
  • A to G, chromosome 1 at 128,307,980 bp
  • A to G, chromosome 1 at 191,056,361 bp
  • T to A, chromosome 2 at 89,657,172 bp
  • T to C, chromosome 2 at 89,993,417 bp
  • T to C, chromosome 2 at 111,420,078 bp
  • T to C, chromosome 2 at 120,862,721 bp
  • T to C, chromosome 2 at 126,814,745 bp
  • T to C, chromosome 2 at 132,831,680 bp
  • T to A, chromosome 2 at 181,221,666 bp
  • A to G, chromosome 3 at 52,345,837 bp
  • C to A, chromosome 3 at 87,995,643 bp
  • A to T, chromosome 3 at 121,207,369 bp
  • A to T, chromosome 4 at 86,212,691 bp
  • A to T, chromosome 4 at 101,616,577 bp
  • A to G, chromosome 4 at 140,748,127 bp
  • C to T, chromosome 4 at 155,610,026 bp
  • A to T, chromosome 6 at 42,040,100 bp
  • G to T, chromosome 6 at 59,353,672 bp
  • T to G, chromosome 6 at 124,231,772 bp
  • T to A, chromosome 6 at 129,740,284 bp
  • A to G, chromosome 6 at 141,940,017 bp
  • A to T, chromosome 6 at 146,396,951 bp
  • T to C, chromosome 7 at 76,318,120 bp
  • T to A, chromosome 7 at 80,343,584 bp
  • C to T, chromosome 7 at 110,139,306 bp
  • G to A, chromosome 8 at 33,236,429 bp
  • T to C, chromosome 8 at 120,010,671 bp
  • A to G, chromosome 9 at 7,350,050 bp
  • A to G, chromosome 9 at 43,113,608 bp
  • A to T, chromosome 9 at 58,026,704 bp
  • A to T, chromosome 9 at 108,297,251 bp
  • A to G, chromosome 10 at 57,811,262 bp
  • C to T, chromosome 10 at 75,031,270 bp
  • T to C, chromosome 11 at 49,148,695 bp
  • T to C, chromosome 11 at 76,212,934 bp
  • A to T, chromosome 13 at 65,049,306 bp
  • G to A, chromosome 13 at 92,522,666 bp
  • G to A, chromosome 14 at 32,660,657 bp
  • T to A, chromosome 14 at 56,376,155 bp
  • A to T, chromosome 15 at 94,282,483 bp
  • T to C, chromosome 15 at 99,941,997 bp
  • A to T, chromosome 16 at 42,292,187 bp
  • G to A, chromosome 16 at 44,159,527 bp
  • T to C, chromosome 16 at 93,866,442 bp
  • G to A, chromosome 17 at 26,067,869 bp
  • G to A, chromosome 17 at 37,574,535 bp
  • A to G, chromosome 17 at 66,693,862 bp
  • T to C, chromosome 17 at 71,992,100 bp
  • T to G, chromosome 17 at 83,445,950 bp
  • T to C, chromosome 19 at 8,948,331 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6044 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044212-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.