Strain Name:
C57BL/6J-MtgxR6062Btlr
Stock Number:
044227-MU
Citation ID:
RRID:MMRRC_044227-MU
Other Names:
R6062 (G1)
Major Collection:

Gene Information

Gabrg1
Name: gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
Synonyms: GabaA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14405
HGNC: HGNC:4086
Homologene: 22570
Mbtps1
Name: membrane-bound transcription factor peptidase, site 1
Synonyms: S1P, 0610038M03Rik, site-1 protease, subtilisin/kexin isozyme-1, SKI-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56453
Homologene: 2808
Atm
Name: ataxia telangiectasia mutated
Synonyms: C030026E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11920
HGNC: HGNC:795
Homologene: 30952
Csnk2a2
Name: casein kinase 2, alpha prime polypeptide
Synonyms: 1110035J23Rik, CK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 13000
HGNC: HGNC:2459
Homologene: 20444
Eefsec
Name: eukaryotic elongation factor, selenocysteine-tRNA-specific
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 65967
Homologene: 11073
Rapgef1
Name: Rap guanine nucleotide exchange factor (GEF) 1
Synonyms: C3G, Grf2, 4932418O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 107746
HGNC: HGNC:4568
Homologene: 50501
Dtna
Name: dystrobrevin alpha
Synonyms: Dtn, 2210407P21Rik, a-DB-1, alpha-dystrobrevin, A0, 87K protein, adbn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13527
VEGA: 18
HGNC: HGNC:3057
Homologene: 20362
Ecpas
Name: Ecm29 proteasome adaptor and scaffold
Synonyms: AI314180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230249
Homologene: 6056
Cand1
Name: cullin associated and neddylation disassociated 1
Synonyms: 6330512O03Rik, 2310038O07Rik, D10Ertd516e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71902
Homologene: 10202
Brca2
Name: breast cancer 2, early onset
Synonyms: RAB163, Fancd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12190
HGNC: HGNC:1101
Homologene: 41
Hbp1
Name: high mobility group box transcription factor 1
Synonyms: C330012F01Rik, 1700058O05Rik, C86454
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 73389
Homologene: 8171
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: 2610100B16Rik, Ten-m3, Odz3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23965
Homologene: 22673
Septin9
Name: septin 9
Synonyms: Msf, Sint1, Sept9, SL3-3 integration site 1, MSF1, PNUTL4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 53860
HGNC: HGNC:7323
Homologene: 90949
Ola1
Name: Obg-like ATPase 1
Synonyms: 2810409H07Rik, 2510025G09Rik, Gtpbp9, 2810405J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67059
Homologene: 5361
Herpud2
Name: HERPUD family member 2
Synonyms: 5031400M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 80517
VEGA: 9
Homologene: 10756
Rab35
Name: RAB35, member RAS oncogene family
Synonyms: RAB1C, 9530019H02Rik, H-ray
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 77407
HGNC: HGNC:9774
Homologene: 21361
Crtc1
Name: CREB regulated transcription coactivator 1
Synonyms: Mect1, TORC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382056
Homologene: 41607
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225115
Homologene: 25090
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Ginm1
Name: glycoprotein integral membrane 1
Synonyms: BC013529
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215751
Homologene: 16347
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Colec10
Name: collectin sub-family member 10
Synonyms: CL-L1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239447
VEGA: 15
HGNC: HGNC:2220
Homologene: 31381
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Tnn
Name: tenascin N
Synonyms: tenascin-W, Tnw
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329278
Homologene: 18634
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Slc8a3
Name: solute carrier family 8 (sodium/calcium exchanger), member 3
Synonyms: Ncx3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 110893
Homologene: 62645
Rab3d
Name: RAB3D, member RAS oncogene family
Synonyms: C130057E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19340
HGNC: HGNC:9779
Homologene: 20902
Plce1
Name: phospholipase C, epsilon 1
Synonyms: PLCepsilon, 4933403A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74055
Homologene: 9478
Grb14
Name: growth factor receptor bound protein 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 50915
HGNC: HGNC:4565
Homologene: 3303
Golgb1
Name: golgi autoantigen, golgin subfamily b, macrogolgin 1
Synonyms: F730017E11Rik, Gm6840, Giantin, 6330407A06Rik, C130074L01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224139
HGNC: HGNC:4429
Homologene: 68401
Shcbp1
Name: Shc SH2-domain binding protein 1
Synonyms: mPAL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20419
Homologene: 32123
Vmn1r46
Name: vomeronasal 1 receptor 46
Synonyms: V1rb8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113856
Homologene: 134021
Slc2a7
Name: solute carrier family 2 (facilitated glucose transporter), member 7
Synonyms: OTTMUSG00000010396
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 435818
Homologene: 72470
Cdcp2
Name: CUB domain containing protein 2
Synonyms: D030010E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242603
Homologene: 138406
Daglb
Name: diacylglycerol lipase, beta
Synonyms: E330036I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231871
Homologene: 34715
Rgsl1
Name: regulator of G-protein signaling like 1
Synonyms: Rgsl2, 4930415K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240816
Homologene: 129962
Enthd1
Name: ENTH domain containing 1
Synonyms: LOC383075
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 383075
VEGA: 15
Homologene: 45131
Slc28a1
Name: solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
Synonyms: Cnt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434203
Homologene: 37902
Prelid2
Name: PRELI domain containing 2
Synonyms: 1700003A01Rik, C330008K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 77619
VEGA: 18
Homologene: 45749
Erbb2
Name: erb-b2 receptor tyrosine kinase 2
Synonyms: Neu, ErbB-2, l11Jus8, c-erbB2, HER2, HER-2, c-neu, Neu oncogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13866
HGNC: HGNC:3430
Homologene: 3273
Ces4a
Name: carboxylesterase 4A
Synonyms: Ces8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234677
Homologene: 71949
Slc22a19
Name: solute carrier family 22 (organic anion transporter), member 19
Synonyms: D630043A20Rik, Slc22a9, Oat5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 207151
Homologene: 133125
Matn1
Name: matrilin 1, cartilage matrix protein
Synonyms: Mat1, CMP, matrilin-1, Crtm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 17180
HGNC: HGNC:6907
Homologene: 1783
Usp9y
Name: ubiquitin specific peptidase 9, Y chromosome
Synonyms: Fafl2, Dffry
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 107868
Homologene: 68408
Idi1
Name: isopentenyl-diphosphate delta isomerase
Synonyms: 4832416K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319554
HGNC: HGNC:5387
Homologene: 3315
Scel
Name: sciellin
Synonyms: 9230114I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 64929
VEGA: 14
Homologene: 2850
Otud4
Name: OTU domain containing 4
Synonyms: 4930431L18Rik, D8Ertd69e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 73945
Homologene: 35370
Olfr1019
Name: olfactory receptor 1019
Synonyms: MOR180-1, GA_x6K02T2Q125-47320309-47319377
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259017
Homologene: 17464
Tmem267
Name: transmembrane protein 267
Synonyms: Gm7120
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 633640
Homologene: 49708
E330034G19Rik
Name: RIKEN cDNA E330034G19 gene
Synonyms: ZPAC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105418
Atat1
Name: alpha tubulin acetyltransferase 1
Synonyms: 3110080J08Rik, 2610008K08Rik, 0610011P08Rik, 2610110G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 73242
Homologene: 15129
Lrrc32
Name: leucine rich repeat containing 32
Synonyms: Garp, EG434215, D11S833Eh, D7H11S833E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434215
HGNC: HGNC:4161
Homologene: 4027
Olfr912
Name: olfactory receptor 912
Synonyms: MOR165-4, GA_x6K02T2PVTD-32283590-32284522
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258806
VEGA: 9
Homologene: 115510
Zfp382
Name: zinc finger protein 382
Synonyms: 5930415A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233060
Homologene: 32798
Rem1
Name: rad and gem related GTP binding protein 1
Synonyms: E030011C07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19700
Homologene: 7514
Olfr723
Name: olfactory receptor 723
Synonyms: MOR247-4, MOR247-3P, GA_x6K02T2PMLR-5600424-5599495
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 259147
Homologene: 71986
Zfp950
Name: zinc finger protein 950
Synonyms: Zfp826, Gm34518, BC029127
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 414758
Olfr388-ps1
Name: olfactory receptor 388, pseudogene 1
Synonyms: MOR135-22, GA_x6K02T2P1NL-3884648-3883708
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258182
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 153,799,872 bp
  • T to A, chromosome 1 at 160,098,278 bp
  • A to G, chromosome 2 at 29,700,732 bp
  • A to G, chromosome 2 at 52,185,281 bp
  • G to T, chromosome 2 at 65,022,620 bp
  • A to T, chromosome 2 at 73,199,498 bp
  • T to G, chromosome 2 at 85,841,114 bp
  • T to C, chromosome 2 at 152,628,097 bp
  • G to T, chromosome 4 at 58,826,453 bp
  • T to C, chromosome 4 at 107,102,492 bp
  • T to A, chromosome 4 at 130,951,966 bp
  • T to C, chromosome 4 at 150,168,427 bp
  • A to G, chromosome 5 at 70,780,713 bp
  • A to G, chromosome 5 at 115,640,088 bp
  • T to C, chromosome 5 at 143,494,603 bp
  • G to A, chromosome 5 at 150,556,889 bp
  • A to T, chromosome 6 at 88,355,629 bp
  • T to C, chromosome 6 at 89,976,259 bp
  • T to C, chromosome 7 at 30,133,590 bp
  • C to T, chromosome 7 at 81,115,563 bp
  • T to C, chromosome 7 at 98,498,541 bp
  • A to C, chromosome 8 at 4,764,905 bp
  • T to C, chromosome 8 at 16,092,305 bp
  • T to G, chromosome 8 at 48,343,406 bp
  • G to T, chromosome 8 at 70,406,189 bp
  • T to C, chromosome 8 at 79,673,896 bp
  • A to G, chromosome 8 at 95,457,469 bp
  • G to A, chromosome 8 at 105,138,174 bp
  • A to T, chromosome 8 at 119,531,091 bp
  • T to C, chromosome 9 at 21,910,519 bp
  • A to T, chromosome 9 at 25,108,988 bp
  • T to A, chromosome 9 at 38,539,144 bp
  • A to G, chromosome 9 at 53,488,587 bp
  • T to A, chromosome 10 at 7,775,333 bp
  • G to A, chromosome 10 at 119,218,010 bp
  • A to C, chromosome 11 at 73,724,560 bp
  • A to G, chromosome 11 at 98,433,249 bp
  • A to G, chromosome 11 at 117,290,800 bp
  • A to T, chromosome 12 at 31,937,247 bp
  • G to A, chromosome 12 at 81,314,350 bp
  • A to G, chromosome 13 at 8,887,505 bp
  • T to C, chromosome 13 at 119,609,231 bp
  • A to T, chromosome 14 at 24,293,380 bp
  • A to T, chromosome 14 at 49,928,662 bp
  • C to A, chromosome 14 at 103,585,136 bp
  • T to A, chromosome 15 at 54,459,807 bp
  • T to A, chromosome 15 at 80,452,715 bp
  • A to G, chromosome 16 at 32,759,308 bp
  • C to A, chromosome 16 at 36,914,671 bp
  • T to A, chromosome 17 at 35,908,564 bp
  • T to G, chromosome 18 at 5,106,724 bp
  • C to A, chromosome 18 at 23,622,056 bp
  • T to C, chromosome 18 at 31,967,990 bp
  • T to C, chromosome 18 at 41,912,465 bp
  • T to C, chromosome 19 at 7,674,282 bp
  • G to A, chromosome 19 at 38,524,751 bp
  • T to A, chromosome 19 at 61,120,425 bp
  • G to T, chromosome Y at 1,454,199 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6062 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044227-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.