Strain Name:
C57BL/6J-MtgxR6090Btlr
Stock Number:
044247-MU
Citation ID:
RRID:MMRRC_044247-MU
Other Names:
R6090 (G1)
Major Collection:

Gene Information

Notch2
Name: notch 2
Synonyms: Motch B, N2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18129
HGNC: HGNC:7882
Homologene: 7865
Septin4
Name: septin 4
Synonyms: Bh5, Pnutl2, cell division control-related protein 2b, ARTS, Sept4, septin H5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18952
HGNC: HGNC:9165
Homologene: 6107
Sptan1
Name: spectrin alpha, non-erythrocytic 1
Synonyms: Spna2, 2610027H02Rik, Spna-2, alpha-fodrin, alphaII-spectrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20740
Homologene: 2353
Rbm47
Name: RNA binding motif protein 47
Synonyms: 9530077J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 245945
Homologene: 36932
Adgrl3
Name: adhesion G protein-coupled receptor L3
Synonyms: 5430402I23Rik, lectomedin 3, Lphn3, LEC3, D130075K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319387
Homologene: 22878
Proser1
Name: proline and serine rich 1
Synonyms: 2810046L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 212127
Homologene: 13463
Gse1
Name: genetic suppressor element 1, coiled-coil protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382034
Homologene: 40964
Clasp2
Name: CLIP associating protein 2
Synonyms: 1500004F14Rik, CLASP2, CLASP2beta, CLASP2gamma, 8030404L10Rik, CLASP2alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 76499
VEGA: 9
Homologene: 24944
Gfod1
Name: glucose-fructose oxidoreductase domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 328232
VEGA: 13
Homologene: 49581
Pcgf2
Name: polycomb group ring finger 2
Synonyms: mel-18, Rnf110, Mel18, Zfp144
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22658
Homologene: 5174
Hjurp
Name: Holliday junction recognition protein
Synonyms: C330011F01Rik, A730008H23Rik, 6430706D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381280
Homologene: 10184
Rdh11
Name: retinol dehydrogenase 11
Synonyms: Psdr1, M42C60, 2610319N22Rik, Arsdr1, Mdt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 17252
Homologene: 100724
Glg1
Name: golgi apparatus protein 1
Synonyms: CFR, Selel, CFR-1, MG160, MG-160, ESL-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20340
HGNC: HGNC:4316
Homologene: 7533
Cpsf3
Name: cleavage and polyadenylation specificity factor 3
Synonyms: 73 kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 54451
VEGA: 12
HGNC: HGNC:2326
Homologene: 6499
Tyw3
Name: tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
Synonyms: 5230400J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 209584
Homologene: 44531
Dnah1
Name: dynein, axonemal, heavy chain 1
Synonyms: B230373P09Rik, Dnahc1, E030034C22Rik, MDHC7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 110084
VEGA: 14
HGNC: HGNC:2940
Homologene: 67131
Cdipt
Name: CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
Synonyms: D7Bwg0575e, 9530042F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 52858
HGNC: HGNC:1769
Homologene: 7159
Dhx57
Name: DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106794
VEGA: 17
Homologene: 56267
Unc13b
Name: unc-13 homolog B
Synonyms: Munc13-2, Unc13h2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22249
Homologene: 31376
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Dhx36
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 36
Synonyms: Ddx36, 2810407E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72162
Homologene: 6356
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Gm10801
Name: predicted gene 10801
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Stard9
Name: START domain containing 9
Synonyms: 4831403C07Rik, E230025N21Rik, Kif16a, N-3 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668880
Homologene: 130712
A2m
Name: alpha-2-macroglobulin
Synonyms: A2mp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232345
HGNC: HGNC:7
Homologene: 37248
Arntl2
Name: aryl hydrocarbon receptor nuclear translocator-like 2
Synonyms: BMAL2, MOP9, 4632430A05Rik, bHLHe6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 272322
Homologene: 10609
Klrd1
Name: killer cell lectin-like receptor, subfamily D, member 1
Synonyms: CD94
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16643
HGNC: HGNC:6378
Homologene: 1705
Abca8a
Name: ATP-binding cassette, sub-family A (ABC1), member 8a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217258
HGNC: HGNC:38
Homologene: 131160
Pomgnt2
Name: protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2
Synonyms: Gtdc2, C85492
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 215494
VEGA: 9
Homologene: 32795
Rsph10b
Name: radial spoke head 10 homolog B (Chlamydomonas)
Synonyms: 4930526H21Rik, Rsph10b2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Homologene: 18321
Tmem143
Name: transmembrane protein 143
Synonyms: 2310076O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70209
Homologene: 10105
Pcdhb14
Name: protocadherin beta 14
Synonyms: PcdhbN, 2210006M07Rik, Pcdhb17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93885
Homologene: 70876
Tmc4
Name: transmembrane channel-like gene family 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 353499
Homologene: 16971
Lgmn
Name: legumain
Synonyms: AEP, Prsc1, preprolegumain
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19141
HGNC: HGNC:9472
Homologene: 38075
Poll
Name: polymerase (DNA directed), lambda
Synonyms: 1110003P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 56626
VEGA: 19
HGNC: HGNC:9184
Homologene: 40863
Chml
Name: choroideremia-like
Synonyms: E030003F13Rik, Rep2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12663
HGNC: HGNC:1941
Homologene: 31055
Olfr141
Name: olfactory receptor 141
Synonyms: K17, GA_x6K02T2Q125-48299679-48298702, MOR179-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257913
Homologene: 28042
Fbxw20
Name: F-box and WD-40 domain protein 20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 434440
Homologene: 110776
Zfp131
Name: zinc finger protein 131
Synonyms: Znf131, 2610109I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72465
VEGA: 13
Homologene: 12464
Timd2
Name: T cell immunoglobulin and mucin domain containing 2
Synonyms: TIM-2, Tim2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 171284
Homologene: 82236
Fam179b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Gm10081
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • GT to GTT, chromosome 1 at 88,266,524 bp
  • G to T, chromosome 1 at 175,687,058 bp
  • C to T, chromosome 2 at 29,993,887 bp
  • A to G, chromosome 2 at 41,185,868 bp
  • A to C, chromosome 2 at 86,806,357 bp
  • TC to TCGGC, chromosome 2 at 98,663,806 bp
  • T to A, chromosome 2 at 120,693,654 bp
  • A to T, chromosome 3 at 53,478,667 bp
  • G to A, chromosome 3 at 62,496,820 bp
  • A to T, chromosome 3 at 98,135,377 bp
  • T to C, chromosome 3 at 154,597,067 bp
  • C to A, chromosome 4 at 43,239,306 bp
  • G to C, chromosome 5 at 66,026,283 bp
  • A to T, chromosome 5 at 81,512,326 bp
  • A to T, chromosome 5 at 143,977,128 bp
  • C to T, chromosome 6 at 121,648,013 bp
  • T to C, chromosome 6 at 129,595,536 bp
  • T to A, chromosome 6 at 146,829,696 bp
  • A to G, chromosome 7 at 3,671,053 bp
  • A to G, chromosome 7 at 45,909,526 bp
  • A to G, chromosome 7 at 107,106,249 bp
  • A to T, chromosome 7 at 126,976,959 bp
  • T to A, chromosome 8 at 111,181,035 bp
  • C to A, chromosome 8 at 120,571,169 bp
  • G to A, chromosome 9 at 79,692,393 bp
  • G to T, chromosome 9 at 109,223,363 bp
  • G to T, chromosome 9 at 113,852,735 bp
  • A to T, chromosome 9 at 121,982,797 bp
  • T to C, chromosome 11 at 46,687,236 bp
  • G to A, chromosome 11 at 87,589,517 bp
  • C to T, chromosome 11 at 97,690,991 bp
  • T to C, chromosome 11 at 110,063,222 bp
  • A to G, chromosome 12 at 21,295,193 bp
  • A to G, chromosome 12 at 64,967,801 bp
  • G to T, chromosome 12 at 79,189,064 bp
  • A to T, chromosome 12 at 102,400,154 bp
  • G to T, chromosome 13 at 43,200,961 bp
  • A to T, chromosome 13 at 119,775,996 bp
  • A to T, chromosome 14 at 31,269,425 bp
  • A to G, chromosome 17 at 80,263,946 bp
  • G to A, chromosome 18 at 37,448,606 bp
  • G to T, chromosome 19 at 45,555,997 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6090 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044247-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.