Strain Name:
C57BL/6J-MtgxR6101Btlr
Stock Number:
044251-MU
Citation ID:
RRID:MMRRC_044251-MU
Other Names:
R6101 (G1)
Major Collection:

Gene Information

Thbs4
Name: thrombospondin 4
Synonyms: TSP4, TSP-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 21828
Homologene: 20691
Tnpo3
Name: transportin 3
Synonyms: C430013M08Rik, D6Ertd313e, 5730544L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 320938
Homologene: 40848
Cnot7
Name: CCR4-NOT transcription complex, subunit 7
Synonyms: Caf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 18983
Homologene: 49011
Csrnp1
Name: cysteine-serine-rich nuclear protein 1
Synonyms: CSRNP-1, 4931429D10Rik, taip-3, Axud1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 215418
VEGA: 9
Homologene: 13196
Specc1l
Name: sperm antigen with calponin homology and coiled-coil domains 1-like
Synonyms: 4930470P14Rik, 9530057A13Rik, Specc1l, Cytsa, 4932439K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 74392
VEGA: 10
Homologene: 15610
Fblim1
Name: filamin binding LIM protein 1
Synonyms: Fblp1, 2410043F08Rik, migfilin, migfilin(s)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74202
Homologene: 56774
Cyb5a
Name: cytochrome b5 type A (microsomal)
Synonyms: Cyb5, 0610009N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 109672
HGNC: HGNC:2570
Homologene: 41475
Mical3
Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Synonyms: C130040D16Rik, MICAL-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 194401
Homologene: 85288
Aldh4a1
Name: aldehyde dehydrogenase 4 family, member A1
Synonyms: Ahd-1, Ssdh1, P5CDH, A930035F14Rik, ALDH4, Ahd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 212647
HGNC: HGNC:406
Homologene: 6081
Pikfyve
Name: phosphoinositide kinase, FYVE type zinc finger containing
Synonyms: Pip5k3, 5230400C17Rik, PipkIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18711
Homologene: 32115
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, 4921513O20Rik, D630001M17Rik, 9330188B09Rik, LOC381026
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 66725
Homologene: 18982
Igha
Name: immunoglobulin heavy constant alpha
Synonyms: Igh-2, IgA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238447
Steap2
Name: six transmembrane epithelial antigen of prostate 2
Synonyms: 4921538B17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74051
Homologene: 17682
Glul
Name: glutamate-ammonia ligase (glutamine synthetase)
Synonyms: Glns, GS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14645
HGNC: HGNC:4341
Homologene: 37567
Rpn2
Name: ribophorin II
Synonyms: Rpn-2, 1300012C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20014
Homologene: 2214
Kxd1
Name: KxDL motif containing 1
Synonyms: 2810422J05Rik, 0610030B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 75620
Homologene: 11447
Zkscan17
Name: zinc finger with KRAB and SCAN domains 17
Synonyms: Zfp496, Nizp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 268417
Homologene: 13108
Ptprq
Name: protein tyrosine phosphatase, receptor type, Q
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237523
HGNC: HGNC:9679
Homologene: 83557
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225997
VEGA: 19
Homologene: 9767
Pkd1l3
Name: polycystic kidney disease 1 like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244646
Homologene: 14627
Trim58
Name: tripartite motif-containing 58
Synonyms: LOC386443, LOC216781
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216781
Homologene: 9135
Scn5a
Name: sodium channel, voltage-gated, type V, alpha
Synonyms: SkM2, Nav1.5c, mH1, Nav1.5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20271
Homologene: 22738
Map6
Name: microtubule-associated protein 6
Synonyms: Mtap6, STOP, 2810411E12Rik, F-STOP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17760
HGNC: HGNC:6868
Homologene: 7850
Clstn3
Name: calsyntenin 3
Synonyms: CSTN3, alcadein-beta, Cst-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232370
Homologene: 22836
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: 1110004P15Rik, 2310047C17Rik, DY6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Chl1
Name: cell adhesion molecule L1-like
Synonyms: close homolog of L1, LICAM2, A530023M13Rik, CALL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12661
HGNC: HGNC:1939
Homologene: 21314
Zc3hav1l
Name: zinc finger CCCH-type, antiviral 1-like
Synonyms: B130055L09Rik, E430016P22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 209032
Homologene: 15425
Tdrd12
Name: tudor domain containing 12
Synonyms: 2410004F06Rik, ecat8, 2410070K17Rik, G1-476-14, EG434165, repro23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 71981
Homologene: 87053
Kif2b
Name: kinesin family member 2B
Synonyms: 1700063D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 73470
Homologene: 23775
Olfr1303
Name: olfactory receptor 1303
Synonyms: MOR245-7, Olfr276, MOR245-28_p, MOR245-7, GA_x6K02T2Q125-72882187-72881249, GA_x6K02T2N82Q-3465-3764
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258397
Homologene: 88429
Pnmal2
Name: PNMA-like 2
Synonyms: EG434128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434128
Homologene: 35491
Slc22a30
Name: solute carrier family 22, member 30
Synonyms: C730048C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 319800
Homologene: 77136
Man2a2
Name: mannosidase 2, alpha 2
Synonyms: alpha mannosidase IIx, 1700052O22Rik, MX, 4931438M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 140481
HGNC: HGNC:6825
Homologene: 55954
Postn
Name: periostin, osteoblast specific factor
Synonyms: Osf2, OSF-2, Periostin, A630052E07Rik, peri
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 50706
Homologene: 4730
Adam9
Name: a disintegrin and metallopeptidase domain 9 (meltrin gamma)
Synonyms: MDC9, Mltng, MDC9, Mltng
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11502
HGNC: HGNC:216
Homologene: 20824
Zfp618
Name: zinc finger protein 618
Synonyms: D430033D05Rik, 2810040O04Rik, 2810031P15Rik, Nedd10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 72701
Homologene: 18975
Olfr926
Name: olfactory receptor 926
Synonyms: GA_x6K02T2PVTD-32573036-32573962, MOR171-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258811
VEGA: 9
HGNC: HGNC:8482
Homologene: 128215
Gm10549
Name: predicted gene 10549
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 433171
VEGA: 18
Pak1ip1
Name: PAK1 interacting protein 1
Synonyms: 5830431I15Rik, 5930415H02Rik, Gdpd1, p21-activated protein kinase-interacting protein 1, PIP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 68083
Homologene: 39574
Zfp647
Name: zinc finger protein 647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239546
VEGA: 15
Homologene: 27805
Pinlyp
Name: phospholipase A2 inhibitor and LY6/PLAUR domain containing
Synonyms: 2310033E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 641361
Homologene: 53159
Arhgap11a
Name: Rho GTPase activating protein 11A
Synonyms: GAP (1-12), 6530401L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228482
Homologene: 8862
Olfr917
Name: olfactory receptor 917
Synonyms: GA_x6K02T2PVTD-32368166-32367237, MOR168-2P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258183
VEGA: 9
Adh6b
Name: alcohol dehydrogenase 6B (class V)
Synonyms: Adh5b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 100417514
Homologene: 139477
Olfr533
Name: olfactory receptor 533
Synonyms: MOR252-3P, GA_x6K02T2PBJ9-42615403-42616365
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258056
Homologene: 128384
Mief1
Name: mitochondrial elongation factor 1
Synonyms: Smcr7l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239555
VEGA: 15
Homologene: 10374
Tnfsf10
Name: tumor necrosis factor (ligand) superfamily, member 10
Synonyms: Trail, APO-2L, A330042I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 22035
Homologene: 2824
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 65,264,345 bp
  • T to A, chromosome 1 at 153,906,431 bp
  • A to G, chromosome 2 at 111,814,253 bp
  • G to A, chromosome 2 at 113,834,874 bp
  • T to A, chromosome 2 at 157,310,188 bp
  • A to G, chromosome 3 at 27,335,549 bp
  • A to G, chromosome 3 at 54,372,220 bp
  • T to A, chromosome 3 at 138,357,710 bp
  • A to T, chromosome 4 at 63,133,241 bp
  • C to T, chromosome 4 at 139,638,495 bp
  • G to A, chromosome 4 at 141,584,722 bp
  • T to A, chromosome 5 at 5,675,891 bp
  • G to T, chromosome 6 at 29,588,043 bp
  • A to G, chromosome 6 at 38,293,077 bp
  • A to T, chromosome 6 at 103,693,032 bp
  • A to T, chromosome 6 at 121,033,710 bp
  • A to T, chromosome 6 at 124,461,670 bp
  • T to A, chromosome 7 at 16,946,568 bp
  • C to T, chromosome 7 at 24,545,980 bp
  • A to T, chromosome 7 at 35,481,133 bp
  • T to C, chromosome 7 at 80,367,001 bp
  • T to C, chromosome 7 at 99,268,107 bp
  • T to A, chromosome 7 at 140,466,519 bp
  • A to T, chromosome 8 at 24,970,759 bp
  • C to T, chromosome 8 at 40,510,037 bp
  • A to T, chromosome 8 at 70,519,939 bp
  • A to G, chromosome 8 at 109,640,846 bp
  • A to G, chromosome 9 at 38,665,620 bp
  • T to C, chromosome 9 at 38,877,308 bp
  • A to G, chromosome 9 at 119,522,650 bp
  • T to C, chromosome 9 at 119,973,485 bp
  • T to C, chromosome 10 at 75,248,632 bp
  • A to G, chromosome 10 at 107,580,266 bp
  • A to G, chromosome 11 at 58,651,615 bp
  • A to T, chromosome 11 at 59,503,575 bp
  • A to G, chromosome 11 at 91,575,988 bp
  • T to A, chromosome 12 at 113,256,397 bp
  • T to A, chromosome 13 at 41,004,885 bp
  • G to T, chromosome 13 at 92,775,485 bp
  • G to A, chromosome 15 at 76,912,085 bp
  • T to C, chromosome 15 at 80,249,740 bp
  • T to C, chromosome 15 at 91,723,135 bp
  • C to A, chromosome 18 at 33,464,305 bp
  • G to A, chromosome 18 at 84,871,593 bp
  • T to C, chromosome 19 at 8,337,868 bp
  • G to A, chromosome 19 at 9,004,099 bp
  • C to T, chromosome 19 at 18,853,748 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6101 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044251-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.