Strain Name:
C57BL/6J-MtgxR6104Btlr
Stock Number:
044254-MU
Citation ID:
RRID:MMRRC_044254-MU
Other Names:
R6104 (G1)
Major Collection:

Gene Information

Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: E330008K23Rik, HALR, Mll3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231051
Homologene: 46480
Ylpm1
Name: YLP motif containing 1
Synonyms: ZAP, Zap3, A930013E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56531
Homologene: 87707
Pogz
Name: pogo transposable element with ZNF domain
Synonyms: 9530006B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229584
Homologene: 9022
Lrba
Name: LPS-responsive beige-like anchor
Synonyms: Lba, D3Ertd775e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80877
HGNC: HGNC:1742
Homologene: 36205
Ythdf3
Name: YTH N6-methyladenosine RNA binding protein 3
Synonyms: 9130022A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229096
Homologene: 34991
Dop1a
Name: DOP1 leucine zipper like protein A
Synonyms: B130005I07Rik, D9Ertd809e, Dopey1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320615
Homologene: 26645
Tmem87a
Name: transmembrane protein 87A
Synonyms: A930025J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 211499
Homologene: 9165
Rps6ka5
Name: ribosomal protein S6 kinase, polypeptide 5
Synonyms: 6330404E13Rik, MSK1, 3110005L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 73086
VEGA: 12
Homologene: 48302
Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13078
VEGA: 17
HGNC: HGNC:2597
Homologene: 68035
Marf1
Name: meiosis regulator and mRNA stability 1
Synonyms: 4921513D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 223989
VEGA: 16
Homologene: 40967
Nckap5l
Name: NCK-associated protein 5-like
Synonyms: C230021P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 380969
Homologene: 18924
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Ppfia1
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
Synonyms: liprin, C030014K08Rik, Liprin-alpha1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233977
HGNC: HGNC:9245
Homologene: 20802
Tenm4
Name: teneurin transmembrane protein 4
Synonyms: l(7)-3Rn, Ten-m4, Doc4, l7Rn3, ELM2, Odz4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 23966
Homologene: 8034
Pxylp1
Name: 2-phosphoxylose phosphatase 1
Synonyms: 9430094M07Rik, C130099A20Rik, Acpl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235534
Homologene: 15931
Rsrc1
Name: arginine/serine-rich coiled-coil 1
Synonyms: SRrp53, 1200013F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66880
Homologene: 41147
Chd6
Name: chromodomain helicase DNA binding protein 6
Synonyms: 6330406J24Rik, 5430439G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71389
Homologene: 32772
Atrip
Name: ATR interacting protein
Synonyms: 6620401K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235610
Homologene: 15601
Slc29a3
Name: solute carrier family 29 (nucleoside transporters), member 3
Synonyms: Ent3, 4933435C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71279
Homologene: 56805
Tlr3
Name: toll-like receptor 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 142980
Homologene: 20696
Fzd2
Name: frizzled class receptor 2
Synonyms: Mfz10a, Mfz10, Fz10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 57265
HGNC: HGNC:4040
Homologene: 20377
Grm6
Name: glutamate receptor, metabotropic 6
Synonyms: mGluR6, nerg1, nob3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 108072
HGNC: HGNC:4598
Homologene: 20232
Itgam
Name: integrin alpha M
Synonyms: complement component receptor 3 alpha, CD11B (p170), Mac-1 alpha, Mac-1, complement receptor type 3, CR3, CD11b/CD18, Mac-1a, F730045J24Rik, Ly-40, Cd11b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16409
HGNC: HGNC:6149
Homologene: 526
Olfr59
Name: olfactory receptor 59
Synonyms: IH3, MOR133-3P, GA_x6K02T2P1NL-4434429-4435400
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18359
Homologene: 73924
Il17a
Name: interleukin 17A
Synonyms: Ctla8, Ctla-8, Il17, IL-17A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16171
HGNC: HGNC:5981
Homologene: 1651
Oas3
Name: 2'-5' oligoadenylate synthetase 3
Synonyms: 2'-5' oligoadenylate synthetase-like 10, Oasl10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 246727
HGNC: HGNC:8088
Homologene: 4510
Rnpepl1
Name: arginyl aminopeptidase (aminopeptidase B)-like 1
Synonyms: 1110014H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108657
Homologene: 36367
Vmn2r80
Name: vomeronasal 2, receptor 80
Synonyms: EG624765
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 624765
Homologene: 83483
Fads2b
Name: fatty acid desaturase 2B
Synonyms: 4833423E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228151
Homologene: 105643
Topaz1
Name: testis and ovary specific PAZ domain containing 1
Synonyms: Gm9524
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 671232
VEGA: 9
Homologene: 19835
Myo5b
Name: myosin VB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17919
HGNC: HGNC:7603
Homologene: 49481
Olfr1104
Name: olfactory receptor 1104
Synonyms: GA_x6K02T2Q125-48508763-48507833, MOR207-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258763
Homologene: 64916
Syt10
Name: synaptotagmin X
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 54526
Homologene: 10303
Acot11
Name: acyl-CoA thioesterase 11
Synonyms: BFIT1, 2010309H15Rik, Them1, 1110020M10Rik, Thea
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329910
Homologene: 11977
Myo18b
Name: myosin XVIIIb
Synonyms: 4932408L24Rik, 4933411E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74376
Homologene: 53435
Scn11a
Name: sodium channel, voltage-gated, type XI, alpha
Synonyms: SNS2, NaN, NaT, NSS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 24046
VEGA: 9
Homologene: 8041
Thoc2l
Name: THO complex subunit 2-like
Synonyms: Gm3179, BC005561
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100042165
Rcn3
Name: reticulocalbin 3, EF-hand calcium binding domain
Synonyms: 6030455P07Rik, RLP49, D7Ertd671e, D530026G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 52377
Homologene: 10775
Xylb
Name: xylulokinase homolog (H. influenzae)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102448
VEGA: 9
Homologene: 3746
Fbxo6
Name: F-box protein 6
Synonyms: Fbx6b, FBG2, Fbs2, Fbxo6b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 50762
Homologene: 9274
Nelfcd
Name: negative elongation factor complex member C/D, Th1l
Synonyms: 2410003I03Rik, trihydrophobin 1, Th1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 57314
Homologene: 9496
Desi2
Name: desumoylating isopeptidase 2
Synonyms: 5830417C01Rik, Fam152a, Pppde1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78825
Homologene: 56741
Taar8b
Name: trace amine-associated receptor 8B
Synonyms: LOC382348
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 382348
Homologene: 77586
Nt5c1b
Name: 5'-nucleotidase, cytosolic IB
Synonyms: 4921514H13Rik, CN-IB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 70881
Homologene: 12370
Gpr15
Name: G protein-coupled receptor 15
Synonyms: 4933439K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 71223
VEGA: 16
HGNC: HGNC:4469
Homologene: 3869
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 20,732,274 bp
  • A to G, chromosome 1 at 92,915,884 bp
  • G to A, chromosome 1 at 178,249,452 bp
  • T to A, chromosome 2 at 85,508,349 bp
  • T to C, chromosome 2 at 87,021,713 bp
  • A to G, chromosome 2 at 120,394,424 bp
  • T to C, chromosome 2 at 161,014,132 bp
  • T to C, chromosome 2 at 174,423,457 bp
  • G to A, chromosome 3 at 16,205,161 bp
  • C to T, chromosome 3 at 66,994,649 bp
  • C to A, chromosome 3 at 86,353,792 bp
  • A to G, chromosome 3 at 94,880,031 bp
  • A to T, chromosome 4 at 106,755,897 bp
  • A to T, chromosome 4 at 148,149,522 bp
  • T to C, chromosome 5 at 25,299,129 bp
  • T to A, chromosome 5 at 104,518,218 bp
  • T to C, chromosome 5 at 112,874,291 bp
  • T to A, chromosome 5 at 120,761,693 bp
  • A to G, chromosome 7 at 45,091,523 bp
  • A to T, chromosome 7 at 96,837,289 bp
  • A to G, chromosome 7 at 128,116,302 bp
  • A to G, chromosome 7 at 144,491,574 bp
  • A to G, chromosome 8 at 45,403,093 bp
  • A to T, chromosome 9 at 86,520,807 bp
  • A to C, chromosome 9 at 96,824,747 bp
  • C to T, chromosome 9 at 109,065,564 bp
  • T to A, chromosome 9 at 119,364,507 bp
  • A to G, chromosome 9 at 119,795,678 bp
  • A to G, chromosome 9 at 122,749,866 bp
  • A to T, chromosome 10 at 24,092,237 bp
  • A to G, chromosome 10 at 60,721,002 bp
  • A to C, chromosome 10 at 79,149,020 bp
  • T to A, chromosome 11 at 50,859,317 bp
  • C to A, chromosome 11 at 74,289,366 bp
  • T to C, chromosome 11 at 102,606,335 bp
  • A to G, chromosome 12 at 10,372,955 bp
  • G to A, chromosome 12 at 85,029,630 bp
  • A to T, chromosome 12 at 100,553,148 bp
  • G to A, chromosome 13 at 11,799,825 bp
  • A to T, chromosome 15 at 89,826,864 bp
  • C to T, chromosome 15 at 99,423,988 bp
  • G to A, chromosome 16 at 14,117,455 bp
  • A to G, chromosome 16 at 58,717,976 bp
  • T to A, chromosome 17 at 79,710,205 bp
  • T to A, chromosome 18 at 74,700,679 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6104 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044254-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.