Strain Name:
C57BL/6J-MtgxR6136Btlr
Stock Number:
044283-MU
Citation ID:
RRID:MMRRC_044283-MU
Other Names:
R6136 (G1)
Major Collection:

Gene Information

Rbm47
Name: RNA binding motif protein 47
Synonyms: 9530077J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 245945
Homologene: 36932
Arhgef18
Name: rho/rac guanine nucleotide exchange factor (GEF) 18
Synonyms: D030053O22Rik, A430078G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 319493
Homologene: 32254
Specc1l
Name: sperm antigen with calponin homology and coiled-coil domains 1-like
Synonyms: 4930470P14Rik, 4932439K10Rik, 9530057A13Rik, Specc1l, Cytsa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 74392
VEGA: 10
Homologene: 15610
Rap1a
Name: RAS-related protein 1a
Synonyms: Rap1, Krev-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 109905
HGNC: HGNC:9855
Homologene: 2162
Setx
Name: senataxin
Synonyms: Als4, A930037J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269254
HGNC: HGNC:445
Homologene: 41003
Urb2
Name: URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382038
Homologene: 8859
Sbno1
Name: strawberry notch 1
Synonyms: 9330180L10Rik, sno
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243272
Homologene: 10055
Fcho2
Name: FCH domain only 2
Synonyms: 5832424M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218503
VEGA: 13
Homologene: 9030
Nampt
Name: nicotinamide phosphoribosyltransferase
Synonyms: 1110035O14Rik, Visfatin, Pbef1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 59027
VEGA: 12
Homologene: 4201
Tshr
Name: thyroid stimulating hormone receptor
Synonyms: pet, hyt, hypothroid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 22095
Homologene: 315
Tfcp2
Name: transcription factor CP2
Synonyms: D230015P20Rik, Tcfcp2, CP-2, LBP1, LSF, CP2, LBP-1c, UBP-1, LBP-1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 21422
VEGA: 15
Homologene: 4134
Fzd7
Name: frizzled class receptor 7
Synonyms: Fz7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14369
HGNC: HGNC:4045
Homologene: 20751
Rasal1
Name: RAS protein activator like 1 (GAP1 like)
Synonyms: MRASAL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19415
HGNC: HGNC:9873
Homologene: 3423
Ubr3
Name: ubiquitin protein ligase E3 component n-recognin 3
Synonyms: 1110059H15Rik, A130030D10Rik, 4833421P10Rik, Zfp650
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68795
Homologene: 52092
Hpgd
Name: hydroxyprostaglandin dehydrogenase 15 (NAD)
Synonyms: 15-PGDH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 15446
HGNC: HGNC:5154
Homologene: 68095
Heatr6
Name: HEAT repeat containing 6
Synonyms: 2700008B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217026
Homologene: 11116
Atrip
Name: ATR interacting protein
Synonyms: 6620401K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235610
Homologene: 15601
Nop53
Name: NOP53 ribosome biogenesis factor
Synonyms: 9430097C02Rik, Gltscr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68077
HGNC: HGNC:4333
Homologene: 44130
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: 2210407G14Rik, E530005C20Rik, LOC224126, Hapip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Atp10a
Name: ATPase, class V, type 10A
Synonyms: pfatp, Atp10c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11982
Homologene: 56461
Tns2
Name: tensin 2
Synonyms: Tenc1, nph, nep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 209039
VEGA: 15
Homologene: 37077
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233651
Homologene: 2771
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: syne-2, diminished cone electroretinogram, Cpfl8, dice, Nesp2g, nesprin-2, 6820443O06Rik, D12Ertd777e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Spats2l
Name: spermatogenesis associated, serine-rich 2-like
Synonyms: A230104H11Rik, 2810022L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67198
Homologene: 56711
Miox
Name: myo-inositol oxygenase
Synonyms: RSOR, Aldrl6, C85427, 0610009I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 56727
Homologene: 9732
Wdr11
Name: WD repeat domain 11
Synonyms: 2900055P10Rik, Wdr11, Brwd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 207425
Homologene: 41229
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: LOC380889, 4921531P07Rik, Dnahc12, DHC3, HL19, DLP12, HL-19, Hdhc3, Dnahc7l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Slc1a1
Name: solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
Synonyms: MEAAC1, D130048G10Rik, EAAT3, EAAC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20510
Homologene: 20881
Vmn2r61
Name: vomeronasal 2, receptor 61
Synonyms: Casr-rs2, Gprc2a-rs2, EG637873
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 637873
Homologene: 129683
Abca15
Name: ATP-binding cassette, sub-family A (ABC1), member 15
Synonyms: 4930500I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 320631
Homologene: 87255
1700022I11Rik
Name: RIKEN cDNA 1700022I11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67317
Homologene: 52406
Cblif
Name: cobalamin binding intrinsic factor
Synonyms: Gif
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14603
HGNC: HGNC:4268
Homologene: 3773
Ralgds
Name: ral guanine nucleotide dissociation stimulator
Synonyms: Gnds, Rgds, RalGDS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19730
HGNC: HGNC:9842
Homologene: 4562
Chadl
Name: chondroadherin-like
Synonyms: D930017K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 214685
Homologene: 130044
Olfr1037
Name: olfactory receptor 1037
Synonyms: MOR256-34P, MOR171-52, GA_x6K02T2Q125-47560740-47559775
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259151
Homologene: 66572
3100002H09Rik
Name: RIKEN cDNA 3100002H09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Pik3cg
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Synonyms: PI3Kgamma, PI3Kgamma, p110gamma, PI(3)Kgamma, 5830428L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 30955
HGNC: HGNC:8978
Homologene: 68269
Galnt13
Name: polypeptide N-acetylgalactosaminyltransferase 13
Synonyms: pp-GalNAc-T13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 271786
Homologene: 62167
Ncf1
Name: neutrophil cytosolic factor 1
Synonyms: p47phox, p47phox, NOXO2, Ncf-1, NADPH oxidase subunit (47kDa)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17969
HGNC: HGNC:7660
Homologene: 30964
Rassf8
Name: Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Synonyms: 5133400D11Rik, mHoj-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71323
Homologene: 5219
Cox11
Name: cytochrome c oxidase assembly protein 11, copper chaperone
Synonyms: 2010004I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69802
HGNC: HGNC:2261
Homologene: 3221
3425401B19Rik
Name: RIKEN cDNA 3425401B19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100504518
VEGA: 14
Homologene: 54908
Steap4
Name: STEAP family member 4
Synonyms: Tnfaip9, Tiarp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 117167
Homologene: 36422
Ecd
Name: ecdysoneless cell cycle regulator
Synonyms: 5730461K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 70601
VEGA: 14
Homologene: 5256
Zfp647
Name: zinc finger protein 647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239546
VEGA: 15
Homologene: 27805
Arsj
Name: arylsulfatase J
Synonyms: 9330196J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 271970
Homologene: 35257
Vmn1r202
Name: vomeronasal 1 receptor 202
Synonyms: V1ri7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171258
Homologene: 110880
Chrng
Name: cholinergic receptor, nicotinic, gamma polypeptide
Synonyms: Achr-3, Acrg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11449
HGNC: HGNC:1967
Homologene: 3810
Ifnlr1
Name: interferon lambda receptor 1
Synonyms: Il28ra, IFNLR1, CRF2-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242700
Homologene: 52086
Slc7a12
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
Synonyms: Asc-2, XAT1, asc-type amino acid transporter 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 140918
Homologene: 76812
Gm5624
Name: predicted gene 5624
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 57,902,143 bp
  • T to G, chromosome 1 at 59,483,260 bp
  • G to A, chromosome 1 at 87,209,801 bp
  • T to C, chromosome 2 at 28,550,565 bp
  • A to G, chromosome 2 at 29,148,027 bp
  • G to T, chromosome 2 at 54,516,479 bp
  • A to G, chromosome 2 at 69,993,763 bp
  • A to G, chromosome 2 at 86,084,901 bp
  • T to A, chromosome 2 at 125,403,132 bp
  • C to A, chromosome 3 at 14,499,126 bp
  • A to G, chromosome 3 at 105,750,282 bp
  • T to C, chromosome 3 at 126,364,775 bp
  • T to C, chromosome 4 at 42,972,853 bp
  • C to A, chromosome 4 at 124,610,388 bp
  • A to G, chromosome 4 at 135,703,797 bp
  • G to A, chromosome 5 at 7,978,562 bp
  • G to C, chromosome 5 at 66,026,283 bp
  • T to C, chromosome 5 at 120,675,478 bp
  • T to C, chromosome 5 at 124,378,491 bp
  • T to C, chromosome 5 at 134,226,633 bp
  • A to G, chromosome 6 at 145,815,656 bp
  • G to A, chromosome 7 at 15,938,389 bp
  • G to T, chromosome 7 at 42,267,031 bp
  • A to C, chromosome 7 at 58,828,340 bp
  • T to G, chromosome 7 at 105,760,925 bp
  • A to T, chromosome 7 at 120,340,049 bp
  • T to A, chromosome 7 at 129,618,703 bp
  • T to C, chromosome 8 at 3,454,507 bp
  • A to G, chromosome 8 at 56,294,952 bp
  • A to G, chromosome 8 at 124,030,092 bp
  • T to A, chromosome 9 at 109,071,736 bp
  • A to G, chromosome 10 at 75,246,660 bp
  • T to A, chromosome 11 at 83,772,503 bp
  • T to C, chromosome 11 at 90,644,395 bp
  • A to G, chromosome 12 at 32,204,359 bp
  • A to T, chromosome 12 at 32,830,302 bp
  • A to G, chromosome 12 at 75,905,325 bp
  • A to G, chromosome 12 at 91,538,234 bp
  • T to C, chromosome 13 at 22,501,462 bp
  • T to C, chromosome 13 at 98,789,767 bp
  • T to C, chromosome 14 at 20,320,791 bp
  • A to G, chromosome 14 at 26,875,270 bp
  • A to T, chromosome 14 at 32,662,282 bp
  • A to T, chromosome 14 at 44,559,876 bp
  • G to A, chromosome 15 at 76,912,085 bp
  • T to C, chromosome 15 at 81,693,554 bp
  • T to C, chromosome 15 at 89,335,321 bp
  • G to T, chromosome 15 at 100,512,313 bp
  • T to A, chromosome 15 at 102,107,030 bp
  • T to G, chromosome 16 at 34,357,111 bp
  • G to A, chromosome 19 at 11,750,285 bp
  • T to A, chromosome 19 at 28,905,410 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6136 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044283-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.