Strain Name:
C57BL/6J-MtgxR6152Btlr
Stock Number:
044299-MU
Citation ID:
RRID:MMRRC_044299-MU
Other Names:
R6152 (G1)
Major Collection:

Gene Information

Dgat2
Name: diacylglycerol O-acyltransferase 2
Synonyms: 0610010B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67800
Homologene: 23580
Prpf6
Name: pre-mRNA splicing factor 6
Synonyms: 1190003A07Rik, ANT-1, 2610031L17Rik, U5-102K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68879
Homologene: 5368
Kazn
Name: kazrin, periplakin interacting protein
Synonyms: 9030409G11Rik, 2310007B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 71529
Homologene: 16235
Anln
Name: anillin, actin binding protein
Synonyms: Scraps, 1110037A17Rik, 2900037I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 68743
VEGA: 9
Homologene: 41281
Afg3l2
Name: AFG3-like AAA ATPase 2
Synonyms: 2310036I02Rik, Emv66, par
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 69597
VEGA: 18
HGNC: HGNC:315
Homologene: 4947
Mcm2
Name: minichromosome maintenance complex component 2
Synonyms: CDCL1, BM28, Mcmd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 17216
HGNC: HGNC:6944
Homologene: 3325
Chpf
Name: chondroitin polymerizing factor
Synonyms: 1700028N03Rik, D1Bwg1363e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74241
Homologene: 11574
Hrct1
Name: histidine rich carboxyl terminus 1
Synonyms: 3830408D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100039781
Pfkl
Name: phosphofructokinase, liver, B-type
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 18641
HGNC: HGNC:8876
Homologene: 55668
Hmg20a
Name: high mobility group 20A
Synonyms: Hmgxb1, 5730490E10Rik, 1200004E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 66867
VEGA: 9
HGNC: HGNC:5001
Homologene: 32399
Fbxo7
Name: F-box protein 7
Synonyms: A230052G17Rik, 2410015K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 69754
Homologene: 8136
Ndfip2
Name: Nedd4 family interacting protein 2
Synonyms: N4wbp5a, 0710001O20Rik, 9130207N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 76273
Homologene: 12636
Slc25a36
Name: solute carrier family 25, member 36
Synonyms: C330005L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 192287
Homologene: 10039
Cblb
Name: Casitas B-lineage lymphoma b
Synonyms: Cbl-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 208650
VEGA: 16
HGNC: HGNC:1542
Homologene: 15856
Susd2
Name: sushi domain containing 2
Synonyms: 1200011D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71733
VEGA: 10
Homologene: 10481
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545370
Homologene: 23741
Cntnap5c
Name: contactin associated protein-like 5C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 620292
VEGA: 17
Homologene: 128806
Pcdhb5
Name: protocadherin beta 5
Synonyms: PcdhbE, Pcdhb4A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93876
HGNC: HGNC:8689
Homologene: 75103
Col19a1
Name: collagen, type XIX, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12823
HGNC: HGNC:2196
Homologene: 55608
Gm15130
Name: predicted gene 15130
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
Zdhhc8
Name: zinc finger, DHHC domain containing 8
Synonyms: E330009O14Rik, Op53c05, D16H22S1738E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 27801
VEGA: 16
Homologene: 8363
Sult6b2
Name: sulfotransferase family 6B, member 2
Synonyms: Gm766, LOC330440
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330440
Homologene: 66632
Abca5
Name: ATP-binding cassette, sub-family A (ABC1), member 5
Synonyms: ABC13, B930033A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217265
HGNC: HGNC:35
Homologene: 10263
Pcnx2
Name: pecanex homolog 2
Synonyms: E330039K12Rik, Pcnxl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 270109
HGNC: HGNC:8736
Homologene: 8987
Cabs1
Name: calcium binding protein, spermatid specific 1
Synonyms: 4931407G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70977
Homologene: 13225
Mamdc4
Name: MAM domain containing 4
Synonyms: LOC381352
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 381352
Homologene: 17102
Atp11a
Name: ATPase, class VI, type 11A
Synonyms: 9130422H11Rik, LOC100045280, Ih, 4930558F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 50770
Homologene: 75050
Pacsin2
Name: protein kinase C and casein kinase substrate in neurons 2
Synonyms: Syndapin II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 23970
VEGA: 15
HGNC: HGNC:8571
Homologene: 21414
Zbtb6
Name: zinc finger and BTB domain containing 6
Synonyms: Zfp482, A830092L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241322
Homologene: 4829
Olfr1357
Name: olfactory receptor 1357
Synonyms: GA_x6K02T2QGN0-3196801-3197742, MOR128-4, MOR128-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 257883
HGNC: HGNC:8207
Homologene: 72920
Pon3
Name: paraoxonase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 269823
HGNC: HGNC:9206
Homologene: 37371
Zkscan16
Name: zinc finger with KRAB and SCAN domains 16
Synonyms: Zfp483
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100041581
Homologene: 26419
Lrrc39
Name: leucine rich repeat containing 39
Synonyms: 2010005E21Rik, Myomasp, 9430028I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 109245
Homologene: 13668
Olfr1449
Name: olfactory receptor 1449
Synonyms: GA_x6K02T2RE5P-3264213-3265157, MOR202-34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258300
Homologene: 17184
Idh1
Name: isocitrate dehydrogenase 1 (NADP+), soluble
Synonyms: IDPc, Idh-1, Id-1, E030024J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 15926
HGNC: HGNC:5382
Homologene: 21195
Cep250
Name: centrosomal protein 250
Synonyms: B230210E21Rik, Cep2, Inmp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16328
HGNC: HGNC:1859
Homologene: 38286
Gpr161
Name: G protein-coupled receptor 161
Synonyms: vl, LOC240888
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240888
Homologene: 17824
Klhdc3
Name: kelch domain containing 3
Synonyms: 1300011D16Rik, Peas
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 71765
VEGA: 17
Homologene: 14290
Sh3yl1
Name: Sh3 domain YSC-like 1
Synonyms: Ray, YSC84
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 24057
Homologene: 31662
Atoh7
Name: atonal bHLH transcription factor 7
Synonyms: bHLHa13, Math5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 53404
VEGA: 10
Homologene: 32338
Tysnd1
Name: trypsin domain containing 1
Synonyms: 1300019N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71767
VEGA: 10
Homologene: 87946
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 24,374,621 bp
  • T to C, chromosome 1 at 65,159,530 bp
  • C to T, chromosome 1 at 75,475,643 bp
  • T to C, chromosome 1 at 150,565,425 bp
  • T to A, chromosome 1 at 165,310,295 bp
  • T to C, chromosome 2 at 25,567,439 bp
  • A to C, chromosome 2 at 37,429,243 bp
  • T to A, chromosome 2 at 111,144,605 bp
  • A to G, chromosome 2 at 155,981,438 bp
  • A to G, chromosome 2 at 181,621,787 bp
  • G to T, chromosome 3 at 116,570,975 bp
  • T to A, chromosome 4 at 43,727,498 bp
  • A to G, chromosome 4 at 58,946,260 bp
  • A to G, chromosome 4 at 142,109,287 bp
  • C to T, chromosome 5 at 87,979,754 bp
  • G to A, chromosome 6 at 5,221,716 bp
  • TTCTGATAGATGGTCTG to TTCTG, chromosome 6 at 88,889,909 bp
  • A to C, chromosome 6 at 142,804,376 bp
  • T to C, chromosome 7 at 99,164,678 bp
  • T to A, chromosome 8 at 12,846,100 bp
  • T to C, chromosome 8 at 125,753,752 bp
  • A to C, chromosome 9 at 22,360,507 bp
  • A to G, chromosome 9 at 56,481,608 bp
  • A to G, chromosome 9 at 97,100,157 bp
  • A to G, chromosome 10 at 61,696,334 bp
  • A to T, chromosome 10 at 63,100,499 bp
  • C to T, chromosome 10 at 75,638,019 bp
  • A to T, chromosome 10 at 77,990,151 bp
  • T to C, chromosome 10 at 78,612,575 bp
  • A to T, chromosome 10 at 86,024,696 bp
  • A to G, chromosome 11 at 110,313,361 bp
  • A to G, chromosome 12 at 30,942,035 bp
  • A to G, chromosome 14 at 105,298,104 bp
  • A to C, chromosome 15 at 83,377,699 bp
  • G to T, chromosome 16 at 18,223,338 bp
  • T to A, chromosome 16 at 52,141,056 bp
  • A to T, chromosome 17 at 46,677,707 bp
  • A to G, chromosome 17 at 58,286,886 bp
  • T to A, chromosome 18 at 37,322,833 bp
  • G to T, chromosome 18 at 67,421,259 bp
  • A to T, chromosome 19 at 12,935,487 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6152 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044299-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.