Strain Name:
C57BL/6J-MtgxR6226Btlr
Stock Number:
044397-MU
Citation ID:
RRID:MMRRC_044397-MU
Other Names:
R6226 (G1)
Major Collection:

Gene Information

Pitx2
Name: paired-like homeodomain transcription factor 2
Synonyms: Otlx2, Pitx2c, Pitx2b, Pitx2a, Brx1b, Brx1a, Brx1, solurshin, Munc30, Rieg, Ptx2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18741
VEGA: 3
HGNC: HGNC:9005
Homologene: 55454
Sufu
Name: SUFU negative regulator of hedgehog signaling
Synonyms: Su(Fu), 2810026F04Rik, b2b273Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 24069
VEGA: 19
Homologene: 9262
Sptbn1
Name: spectrin beta, non-erythrocytic 1
Synonyms: elf3, Spnb-2, beta fodrin, Spnb2, 9930031C03Rik, non-erythrocytic, brain spectrin, spectrin G, elf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20742
VEGA: 11
Homologene: 2354
Nr2f2
Name: nuclear receptor subfamily 2, group F, member 2
Synonyms: COUP-TF2, 9430015G03Rik, Aporp1, ARP-1, EAR3, Tcfcoup2, COUP-TFII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11819
VEGA: 7
HGNC: HGNC:7976
Homologene: 7628
Ptprk
Name: protein tyrosine phosphatase, receptor type, K
Synonyms: RPTPkappa, PTPk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 19272
VEGA: 10
HGNC: HGNC:9674
Homologene: 55693
Dst
Name: dystonin
Synonyms: A830042E19Rik, Bpag1, Macf2, athetoid, bullous pemphigoid antigen 1, 2310001O04Rik, BPAG1-n, BPAG1, nmf339, bullous pemphigoid antigen 1, ah, Bpag, nmf203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13518
VEGA: 1
HGNC: HGNC:1090
Homologene: 136716
Kdm5b
Name: lysine (K)-specific demethylase 5B
Synonyms: 2010009J12Rik, 2210016I17Rik, D1Ertd202e, Plu1, PLU-1, Rb-Bp2, Jarid1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 75605
VEGA: 1
Homologene: 48448
Anks1
Name: ankyrin repeat and SAM domain containing 1
Synonyms: Odin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224650
VEGA: 17
Homologene: 9068
Pibf1
Name: progesterone immunomodulatory binding factor 1
Synonyms: 1700017E21Rik, 4930513H15Rik, D14Ertd581e, 4933439E17Rik, 4933438D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 52023
VEGA: 14
Homologene: 4628
Nup93
Name: nucleoporin 93
Synonyms: 2410008G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 71805
VEGA: 8
Homologene: 40971
Agrn
Name: agrin
Synonyms: Agrin, nmf380, NMF380
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11603
VEGA: 4
HGNC: HGNC:329
Homologene: 27907
Nckap1
Name: NCK-associated protein 1
Synonyms: Nap1, Hem2, H19, Hem-2, mh19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 50884
VEGA: 2
HGNC: HGNC:7666
Homologene: 8384
Anapc1
Name: anaphase promoting complex subunit 1
Synonyms: Mcpr, Apc1, 2610021O03Rik, tsg24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17222
VEGA: 2
Homologene: 7414
Ptpn21
Name: protein tyrosine phosphatase, non-receptor type 21
Synonyms: PTPD1, PTPRL10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 24000
VEGA: 12
HGNC: HGNC:9651
Homologene: 5110
Nkapd1
Name: NKAP domain containing 1
Synonyms: AU019823, LOC270156
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270156
VEGA: 9
Homologene: 41233
Trim27
Name: tripartite motif-containing 27
Synonyms: Rfp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 19720
VEGA: 13
HGNC: HGNC:9975
Homologene: 111010
Mcm3ap
Name: minichromosome maintenance complex component 3 associated protein
Synonyms: GANP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 54387
VEGA: 10
HGNC: HGNC:6946
Homologene: 2902
Rnd2
Name: Rho family GTPase 2
Synonyms: Arhn, Rohn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11858
VEGA: 11
Homologene: 21123
Spg11
Name: SPG11, spatacsin vesicle trafficking associated
Synonyms: 6030465E24Rik, spastic paraplegia 11, C530005A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 214585
VEGA: 2
Homologene: 41614
Ncam1
Name: neural cell adhesion molecule 1
Synonyms: NCAM-1, CD56, E-NCAM, NCAM-180, NCAM-140, NCAM-120, NCAM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17967
VEGA: 9
HGNC: HGNC:7656
Homologene: 40754
Adam33
Name: a disintegrin and metallopeptidase domain 33
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 110751
VEGA: 2
Homologene: 11881
Dsg2
Name: desmoglein 2
Synonyms: D18Ertd293e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13511
VEGA: 18
HGNC: HGNC:3049
Homologene: 1464
Atad1
Name: ATPase family, AAA domain containing 1
Synonyms: Thorase, 4921525H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 67979
VEGA: 19
Homologene: 5960
Frmd6
Name: FERM domain containing 6
Synonyms: 4930488L10Rik, 2610019M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319710
VEGA: 12
Homologene: 12449
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 171395
VEGA: 11
Homologene: 51376
Tmem98
Name: transmembrane protein 98
Synonyms: Rwhs, 6530411B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 103743
VEGA: 11
Homologene: 9185
Ell3
Name: elongation factor RNA polymerase II-like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269344
VEGA: 2
Homologene: 11859
Foxd3
Name: forkhead box D3
Synonyms: Genesis, Hfh2, CWH3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 15221
VEGA: 4
HGNC: HGNC:3804
Homologene: 49239
Itgae
Name: integrin alpha E, epithelial-associated
Synonyms: alpha-E1, CD103
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16407
VEGA: 11
HGNC: HGNC:6147
Homologene: 113560
Sorcs1
Name: sortilin-related VPS10 domain containing receptor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 58178
VEGA: 19
Homologene: 10967
Olfr1251
Name: olfactory receptor 1251
Synonyms: GA_x6K02T2Q125-51109312-51108356, MOR231-15P, MOR231-24_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 259145
VEGA: 2
Homologene: 74065
Cldnd1
Name: claudin domain containing 1
Synonyms: 1110019C08Rik, Cldn25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224250
VEGA: 16
HGNC: HGNC:1322
Homologene: 10534
Gsap
Name: gamma-secretase activating protein
Synonyms: Pion, A530088I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 212167
VEGA: 5
Homologene: 45504
Zfp941
Name: zinc finger protein 941
Synonyms: BC066028
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 407812
VEGA: 7
Olfr1395
Name: olfactory receptor 1395
Synonyms: MOR277-1, GA_x6K02T2QP88-6286247-6285294
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258877
VEGA: 11
Homologene: 105890
Actn2
Name: actinin alpha 2
Synonyms: 1110008F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 11472
VEGA: 13
HGNC: HGNC:164
Homologene: 31016
Grik3
Name: glutamate receptor, ionotropic, kainate 3
Synonyms: Glur-7, Glur7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 14807
VEGA: 4
HGNC: HGNC:4581
Homologene: 73901
Glis3
Name: GLIS family zinc finger 3
Synonyms: E330013K21Rik, 4833409N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226075
VEGA: 19
Homologene: 34989
Ube2m
Name: ubiquitin-conjugating enzyme E2M
Synonyms: UBC12, 2510040H03Rik, Ubc-rs2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22192
VEGA: 7
Homologene: 2952
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 628870
Homologene: 46008
Shkbp1
Name: Sh3kbp1 binding protein 1
Synonyms: SB1, B930062H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 192192
VEGA: 7
Homologene: 26700
Afap1l2
Name: actin filament associated protein 1-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226250
VEGA: 19
Homologene: 13057
Rpl22l1
Name: ribosomal protein L22 like 1
Synonyms: 3110001N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 68028
VEGA: 3
Homologene: 134718
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: LOC227058, Dnahc7b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227058
VEGA: 1
Homologene: 41287
Col16a1
Name: collagen, type XVI, alpha 1
Synonyms: A530052M23Rik, 2700007F12Rik, [a]1 (XVI) collagen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 107581
VEGA: 4
HGNC: HGNC:2193
Homologene: 1397
Kcnh7
Name: potassium voltage-gated channel, subfamily H (eag-related), member 7
Synonyms: Kv11.3, erg3, 9330137I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 170738
VEGA: 2
Homologene: 13249
Olfr1115
Name: olfactory receptor 1115
Synonyms: GA_x6K02T2Q125-48736906-48737886, MOR264-20, Olfr1530-ps1, MOR273-4P, MOR273-4P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258294
VEGA: 2
Homologene: 27114
Serpina5
Name: serine (or cysteine) peptidase inhibitor, clade A, member 5
Synonyms: alpha-1 antiproteinase, PAI-3, Pci, antitrypsin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 268591
VEGA: 12
HGNC: HGNC:8723
Homologene: 20159
Lrrc74a
Name: leucine rich repeat containing 74A
Synonyms: Gm6772, Lrrc74
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 627607
VEGA: 12
Homologene: 19331
Ankzf1
Name: ankyrin repeat and zinc finger domain containing 1
Synonyms: 1300008P06Rik, D1Ertd161e, 2810025E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 52231
VEGA: 1
Homologene: 41225
Sec14l5
Name: SEC14-like lipid binding 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 665119
VEGA: 16
Homologene: 96163
Dnase2b
Name: deoxyribonuclease II beta
Synonyms: DnaseIIb, Dlad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 56629
VEGA: 3
Homologene: 1052
Cdk15
Name: cyclin-dependent kinase 15
Synonyms: Pftk2, Als2cr7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 271697
Homologene: 64641
H2-T10
Name: histocompatibility 2, T region locus 10
Synonyms: H-2T10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 15024
VEGA: 17
Sgip1
Name: SH3-domain GRB2-like (endophilin) interacting protein 1
Synonyms: 3110007P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 73094
VEGA: 4
Homologene: 13001
Gm12830
Name: predicted gene 12830
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 433746
Pou6f2
Name: POU domain, class 6, transcription factor 2
Synonyms: RPF-1, D130006K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218030
VEGA: 13
Ugt2b36
Name: UDP glucuronosyltransferase 2 family, polypeptide B36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231396
Homologene: 128251
Cts3
Name: cathepsin 3
Synonyms: 1600000I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 117066
VEGA: 13
Trim43b
Name: tripartite motif-containing 43B
Synonyms: Gm8269
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 666747
Homologene: 105432
Usp36
Name: ubiquitin specific peptidase 36
Synonyms: 2700002L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72344
VEGA: 11
Homologene: 11828
Olfr874
Name: olfactory receptor 874
Synonyms: GA_x6K02T2PVTD-31428850-31429782, MOR161-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258882
VEGA: 9
Homologene: 17377
Carmil2
Name: capping protein regulator and myosin 1 linker 2
Synonyms: D130029J02Rik, Rltpr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234695
VEGA: 8
Homologene: 128439
Fank1
Name: fibronectin type 3 and ankyrin repeat domains 1
Synonyms: 1700007B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 66930
VEGA: 7
Homologene: 12055
Rptn
Name: repetin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20129
VEGA: 3
Homologene: 84780
Prss29
Name: protease, serine 29
Synonyms: Isp2, mISP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 114662
VEGA: 17
Homologene: 70877
Gsg1
Name: germ cell associated 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14840
VEGA: 6
Homologene: 7745
Olfr922
Name: olfactory receptor 922
Synonyms: GA_x6K02T2PVTD-32518237-32519172, MOR161-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258777
VEGA: 9
Homologene: 27262
Olfr664
Name: olfactory receptor 664
Synonyms: MOR34-10P, EG667918, GA_x6K02T2PBJ9-7361631-7360711
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 667918
VEGA: 7
Gale
Name: galactose-4-epimerase, UDP
Synonyms: 2310002A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74246
VEGA: 4
HGNC: HGNC:4116
Homologene: 347
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 34,270,874 bp
  • A to C, chromosome 1 at 46,126,668 bp
  • T to C, chromosome 1 at 59,265,633 bp
  • A to G, chromosome 1 at 75,196,594 bp
  • G to T, chromosome 1 at 134,608,878 bp
  • A to T, chromosome 2 at 62,777,559 bp
  • A to G, chromosome 2 at 80,508,781 bp
  • A to G, chromosome 2 at 87,252,392 bp
  • A to T, chromosome 2 at 89,666,989 bp
  • A to T, chromosome 2 at 121,441,777 bp
  • A to G, chromosome 2 at 122,088,262 bp
  • A to G, chromosome 2 at 128,650,372 bp
  • G to A, chromosome 2 at 131,055,610 bp
  • A to G, chromosome 3 at 28,806,527 bp
  • C to G, chromosome 3 at 93,398,130 bp
  • C to T, chromosome 3 at 129,215,842 bp
  • A to G, chromosome 3 at 146,584,563 bp
  • T to C, chromosome 4 at 99,657,024 bp
  • A to G, chromosome 4 at 102,966,195 bp
  • T to A, chromosome 4 at 114,845,049 bp
  • T to C, chromosome 4 at 125,659,789 bp
  • A to T, chromosome 4 at 130,055,089 bp
  • A to G, chromosome 4 at 135,965,605 bp
  • A to G, chromosome 4 at 156,173,609 bp
  • A to G, chromosome 5 at 21,217,431 bp
  • A to G, chromosome 5 at 87,092,130 bp
  • T to A, chromosome 6 at 135,240,112 bp
  • A to G, chromosome 7 at 13,035,888 bp
  • C to A, chromosome 7 at 27,351,980 bp
  • T to G, chromosome 7 at 70,359,996 bp
  • A to T, chromosome 7 at 104,734,036 bp
  • A to G, chromosome 7 at 133,862,198 bp
  • A to T, chromosome 7 at 140,812,485 bp
  • T to C, chromosome 8 at 94,286,537 bp
  • A to G, chromosome 8 at 105,689,032 bp
  • T to A, chromosome 9 at 37,746,137 bp
  • T to C, chromosome 9 at 38,816,370 bp
  • C to T, chromosome 9 at 49,565,004 bp
  • T to C, chromosome 9 at 50,607,770 bp
  • T to C, chromosome 9 at 89,091,275 bp
  • A to G, chromosome 10 at 28,564,103 bp
  • A to G, chromosome 10 at 76,515,706 bp
  • A to T, chromosome 10 at 107,771,206 bp
  • T to C, chromosome 11 at 8,901,287 bp
  • A to G, chromosome 11 at 30,136,054 bp
  • A to G, chromosome 11 at 49,148,833 bp
  • A to G, chromosome 11 at 73,140,757 bp
  • T to C, chromosome 11 at 80,821,394 bp
  • C to T, chromosome 11 at 101,468,999 bp
  • A to T, chromosome 11 at 118,277,274 bp
  • A to G, chromosome 12 at 70,863,911 bp
  • T to A, chromosome 12 at 86,748,457 bp
  • A to G, chromosome 12 at 98,680,116 bp
  • A to T, chromosome 12 at 98,715,172 bp
  • T to C, chromosome 12 at 104,101,778 bp
  • T to C, chromosome 13 at 12,278,967 bp
  • A to T, chromosome 13 at 18,129,154 bp
  • T to C, chromosome 13 at 21,180,916 bp
  • T to A, chromosome 13 at 61,568,721 bp
  • A to G, chromosome 14 at 99,101,119 bp
  • G to A, chromosome 16 at 5,176,565 bp
  • A to T, chromosome 16 at 58,731,300 bp
  • T to A, chromosome 17 at 25,320,539 bp
  • G to A, chromosome 17 at 28,057,330 bp
  • A to T, chromosome 17 at 36,121,083 bp
  • T to A, chromosome 18 at 20,579,449 bp
  • A to G, chromosome 19 at 28,317,302 bp
  • G to T, chromosome 19 at 32,701,587 bp
  • G to A, chromosome 19 at 46,473,654 bp
  • T to A, chromosome 19 at 50,181,414 bp
  • T to C, chromosome 19 at 56,916,128 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6226 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044397-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.