Strain Name:
C57BL/6J-MtgxR6797Btlr/Mmmh
Stock Number:
044910-MU
Citation ID:
RRID:MMRRC_044910-MU
Other Names:
R6797 (G1)
Major Collection:

Strain Information

Krt5
Name: keratin 5
Synonyms: 3300001P10Rik, K5, Krt2-5, Tfip8
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110308
HGNC: HGNC:6442
Homologene: 55461
Slit3
Name: slit guidance ligand 3
Synonyms: Slit1, b2b2362.1Clo
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20564
Homologene: 2303
Kmt2e
Name: lysine (K)-specific methyltransferase 2E
Synonyms: D230038D11Rik, 1810033J14Rik, Mll5, 9530077A04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69188
Homologene: 18822
Med13l
Name: mediator complex subunit 13-like
Synonyms: 2210413I17Rik, Trap240L, 6330591G05Rik, 9030618F05Rik, Thrap2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76199
Homologene: 25256
Ttc27
Name: tetratricopeptide repeat domain 27
Synonyms: 2610511O17Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74196
VEGA: 17
Homologene: 41191
Ppp6r3
Name: protein phosphatase 6, regulatory subunit 3
Synonyms: 4930528G08Rik, D19Bwg1430e, Pp6r3, 9130026N02Rik, Saps3, Pptcs3, D19Ertd703e
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 52036
VEGA: 19
HGNC: HGNC:1173
Homologene: 115911
Tlk1
Name: tousled-like kinase 1
Synonyms: 4930545J15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228012
Homologene: 130657
Tasor2
Name: transcription activation suppressor family member 2
Synonyms: Fam208b, BC016423
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105203
VEGA: 13
Homologene: 26435
Rnd2
Name: Rho family GTPase 2
Synonyms: Rohn, Arhn
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11858
Homologene: 21123
Cckbr
Name: cholecystokinin B receptor
Synonyms: CCK2R, CCK2/gastrin, CCK-B/gastrin receptor, CCKR-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12426
HGNC: HGNC:1571
Homologene: 7258
Magel2
Name: MAGE family member L2
Synonyms: Mage-l2, ns7, nM15, NDNL1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 27385
HGNC: HGNC:6814
Homologene: 8460
Jaml
Name: junction adhesion molecule like
Synonyms: LOC270152, Amica1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270152
Homologene: 17708
Angptl2
Name: angiopoietin-like 2
Synonyms: Arp2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26360
HGNC: HGNC:490
Homologene: 22695
Cenpe
Name: centromere protein E
Synonyms: CENP-E, Kif10, 312kDa, N-7 kinesin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229841
HGNC: HGNC:1856
Homologene: 20429
Hspbp1
Name: HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
Synonyms: 1500019G21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66245
Homologene: 40827
Akr1c18
Name: aldo-keto reductase family 1, member C18
Synonyms: 20alpha-hydroxysteroid dehydrogenase, 20alpha-HSD
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105349
HGNC: HGNC:386
Homologene: 128661
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b1565Clo, b2b3491Clo, Mdnah5, b2b1154Clo, b2b1537Clo, Dnahc5, b2b1134Clo
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Pigg
Name: phosphatidylinositol glycan anchor biosynthesis, class G
Synonyms: Gpi7
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 433931
Homologene: 39421
Srgap3
Name: SLIT-ROBO Rho GTPase activating protein 3
Synonyms: D130026O08Rik, Arhgap14
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 259302
Homologene: 56686
Stc2
Name: stanniocalcin 2
Synonyms: mustc2, Stc2l
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20856
Homologene: 2753
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Pak5
Name: p21 (RAC1) activated kinase 5
Synonyms: Pak5, Pak7, 2900083L08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241656
Homologene: 22211
Wdr64
Name: WD repeat domain 64
Synonyms: 4930511H01Rik, 4930415O10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75820
Homologene: 51634
Gramd1b
Name: GRAM domain containing 1B
Synonyms: A930008A22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235283
Homologene: 18223
Vmn2r102
Name: vomeronasal 2, receptor 102
Synonyms: EG224572
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224572
Homologene: 115024
Hivep1
Name: human immunodeficiency virus type I enhancer binding protein 1
Synonyms: alphaA-CRYBP1, Cryabp1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110521
VEGA: 13
HGNC: HGNC:4920
Homologene: 1596
Cd93
Name: CD93 antigen
Synonyms: C1qrp, AA4.1, 6030404G09Rik, Ly68, C1qr1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17064
Homologene: 7823
Lipn
Name: lipase, family member N
Synonyms: Lipl4, 2210418G03Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 70166
Homologene: 66969
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 628870
Homologene: 46008
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50720
Ofcc1
Name: orofacial cleft 1 candidate 1
Synonyms: Opo, ojoplano
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218165
VEGA: 13
Homologene: 125376
F11
Name: coagulation factor XI
Synonyms: FXI, plasma thromboplastin antecedent, Cf11, 1600027G01Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 109821
HGNC: HGNC:3529
Homologene: 86654
Serpinb9b
Name: serine (or cysteine) peptidase inhibitor, clade B, member 9b
Synonyms: ovalbumin, Spi10, 1600019A21Rik, R86, SPI-CI
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20706
HGNC: HGNC:8955
Homologene: 137240
Vmn2r95
Name: vomeronasal 2, receptor 95
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 328759
Homologene: 115024
Hk3
Name: hexokinase 3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 212032
HGNC: HGNC:4925
Homologene: 55633
Or52ab7
Name: olfactory receptor family 52 subfamily AB member 7
Synonyms: GA_x6K02T2PBJ9-6037823-6038782, MOR23-4P, MOR23-5, Olfr598
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257975
Homologene: 132401
Or11h23
Name: olfactory receptor family 11 subfamily G member 23
Synonyms: MOR106-9P, GA_x6K02T2PMLR-6454789-6455712, Olfr748
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258113
Homologene: 134081
Ocln
Name: occludin
Synonyms: Ocl
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 18260
HGNC: HGNC:8104
Homologene: 1905
Mrgprb8
Name: MAS-related GPR, member B8
Synonyms: MrgB8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404240
Homologene: 83620
Gpr146
Name: G protein-coupled receptor 146
Synonyms: PGR8
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 80290
Homologene: 36472
H2bc12
Name: H2B clustered histone 12
Synonyms: Hist1h2bk
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 319184
Homologene: 135980
Vopp1
Name: vesicular, overexpressed in cancer, prosurvival protein 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232023
Homologene: 12772
Casp14
Name: caspase 14
Synonyms: MICE, mini-ICE
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12365
VEGA: 10
HGNC: HGNC:1502
Homologene: 36304
Fen1
Name: flap structure specific endonuclease 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 14156
HGNC: HGNC:3650
Homologene: 3034
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 90,804,088 bp
  • T to A, chromosome 1 at 175,810,610 bp
  • T to C, chromosome 2 at 33,228,265 bp
  • T to A, chromosome 2 at 70,738,426 bp
  • A to T, chromosome 2 at 136,097,534 bp
  • T to C, chromosome 2 at 148,442,124 bp
  • A to T, chromosome 3 at 135,238,138 bp
  • A to G, chromosome 5 at 23,482,507 bp
  • T to C, chromosome 5 at 108,332,828 bp
  • G to A, chromosome 5 at 118,759,264 bp
  • G to A, chromosome 5 at 139,393,040 bp
  • A to G, chromosome 6 at 57,762,507 bp
  • A to T, chromosome 6 at 112,829,542 bp
  • T to A, chromosome 7 at 4,660,782 bp
  • G to A, chromosome 7 at 48,389,144 bp
  • A to G, chromosome 7 at 62,380,159 bp
  • G to A, chromosome 7 at 103,329,121 bp
  • A to G, chromosome 7 at 105,434,566 bp
  • A to G, chromosome 8 at 45,253,055 bp
  • A to G, chromosome 9 at 40,308,406 bp
  • T to C, chromosome 9 at 45,088,760 bp
  • T to C, chromosome 10 at 78,715,141 bp
  • G to A, chromosome 10 at 107,777,117 bp
  • T to A, chromosome 11 at 31,365,351 bp
  • A to G, chromosome 11 at 35,633,952 bp
  • C to T, chromosome 11 at 101,468,999 bp
  • T to C, chromosome 13 at 3,576,769 bp
  • T to A, chromosome 13 at 4,145,277 bp
  • A to T, chromosome 13 at 22,036,089 bp
  • A to G, chromosome 13 at 33,029,484 bp
  • C to T, chromosome 13 at 40,087,947 bp
  • C to A, chromosome 13 at 42,157,081 bp
  • A to T, chromosome 13 at 55,010,831 bp
  • T to C, chromosome 13 at 100,539,715 bp
  • T to A, chromosome 14 at 50,711,106 bp
  • T to A, chromosome 14 at 61,213,073 bp
  • G to T, chromosome 15 at 28,233,238 bp
  • G to A, chromosome 15 at 28,451,463 bp
  • T to C, chromosome 15 at 101,712,641 bp
  • C to T, chromosome 17 at 18,452,289 bp
  • C to T, chromosome 17 at 19,660,432 bp
  • G to T, chromosome 17 at 74,729,888 bp
  • A to G, chromosome 19 at 3,514,719 bp
  • A to G, chromosome 19 at 10,200,703 bp
  • A to T, chromosome 19 at 34,080,760 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6797 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044910-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.