Strain Name:
C57BL/6J-MtgxR6909Btlr/Mmmh
Stock Number:
045001-MU
Citation ID:
RRID:MMRRC_045001-MU
Other Names:
R6909 (G1)
Major Collection:

Strain Information

Ncor1
Name: nuclear receptor co-repressor 1
Synonyms: A230020K14Rik, N-CoR, 5730405M06Rik, Rxrip13
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20185
HGNC: HGNC:7672
Homologene: 38166
Tln2
Name: talin 2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70549
VEGA: 9
Homologene: 56692
Sim1
Name: single-minded family bHLH transcription factor 1
Synonyms: bHLHe14
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20464
VEGA: 10
Homologene: 3715
Dysf
Name: dysferlin
Synonyms: 2310004N10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 26903
HGNC: HGNC:3097
Homologene: 20748
Atic
Name: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Synonyms: 2610509C24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108147
HGNC: HGNC:794
Homologene: 2983
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Magi1
Name: membrane associated guanylate kinase, WW and PDZ domain containing 1
Synonyms: Gukmi1, Baiap1, BAP1, WWP3, AIP3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14924
HGNC: HGNC:946
Homologene: 31257
Mta3
Name: metastasis associated 3
Synonyms: 1110002J22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 116871
Homologene: 14282
Tspan14
Name: tetraspanin 14
Synonyms: D14Ertd226e, Tm4sf14
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 52588
VEGA: 14
Homologene: 23717
Ano1
Name: anoctamin 1, calcium activated chloride channel
Synonyms: Tmem16a
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101772
Homologene: 75079
Tkfc
Name: triokinase, FMN cyclase
Synonyms: Dak
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225913
VEGA: 19
Homologene: 56710
Map3k4
Name: mitogen-activated protein kinase kinase kinase 4
Synonyms: D17Rp17, D17Rp17e, MAPKKK4, Mekk4, MTK1, Tas, RP17, T-associated sex reversal
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 26407
VEGA: 17
HGNC: HGNC:6856
Homologene: 31346
Llgl2
Name: LLGL2 scribble cell polarity complex component
Synonyms: 9130006H11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217325
HGNC: HGNC:6629
Homologene: 3323
Agrn
Name: agrin
Synonyms: nmf380, NMF380, Agrin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11603
HGNC: HGNC:329
Homologene: 27907
Ptpn2
Name: protein tyrosine phosphatase, non-receptor type 2
Synonyms: TC-PTP, Ptpt
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 19255
HGNC: HGNC:9650
Homologene: 7497
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: b2b327Clo, opm, A630086P08Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 207304
VEGA: 12
Homologene: 9115
Tk2
Name: thymidine kinase 2, mitochondrial
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 57813
Homologene: 3392
Kdm3b
Name: KDM3B lysine (K)-specific demethylase 3B
Synonyms: JHDM2B, Jmjd1b, 5830462I21Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 277250
VEGA: 18
HGNC: HGNC:1337
Homologene: 41145
Scn10a
Name: sodium channel, voltage-gated, type X, alpha
Synonyms: Nav1.8
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20264
VEGA: 9
Homologene: 21300
Scyl2
Name: SCY1-like 2 (S. cerevisiae)
Synonyms: CVAK104, D10Ertd802e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 213326
Homologene: 13349
Mcm4
Name: minichromosome maintenance complex component 4
Synonyms: Cdc21, Mcmd4, mCdc21, 19G
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 17217
VEGA: 16
HGNC: HGNC:6947
Homologene: 40496
Skor2
Name: SKI family transcriptional corepressor 2
Synonyms: Fussel18, Corl2, Gm7348
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 664805
VEGA: 18
Homologene: 64797
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Cmya5
Name: cardiomyopathy associated 5
Synonyms: 2310076E21Rik, Myospryn, 2310076E16Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76469
VEGA: 13
Homologene: 137367
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, D12Ertd777e, diminished cone electroretinogram, Cpfl8, Nesp2g, dice, syne-2, 6820443O06Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 319565
Homologene: 56700
Lmod2
Name: leiomodin 2 (cardiac)
Synonyms: C-Lmod
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 93677
HGNC: HGNC:6648
Homologene: 28302
Eps8l1
Name: EPS8-like 1
Synonyms: DRC3, EPS8R1, 2310051G19Rik, 4632407K17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67425
Homologene: 15767
Lrrc43
Name: leucine rich repeat containing 43
Synonyms: LOC381741
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381741
Homologene: 17662
Gucy2d
Name: guanylate cyclase 2d
Synonyms: guanylyl cyclase D
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14918
Homologene: 71540
Hcn3
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 3
Synonyms: Hac3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 15168
Homologene: 22453
Ccdc168
Name: coiled-coil domain containing 168
Synonyms: Gm8251
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 102636082
VEGA: 1
Homologene: 141149
Abca9
Name: ATP-binding cassette, sub-family A member 9
Synonyms: D630040K07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217262
HGNC: HGNC:39
Homologene: 33332
Impg2
Name: interphotoreceptor matrix proteoglycan 2
Synonyms: PG10.2, IPM200, Spacrcan
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224224
Homologene: 9439
Ino80c
Name: INO80 complex subunit C
Synonyms: D030070L09Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225280
Homologene: 45426
Acp3
Name: acid phosphatase 3
Synonyms: PAP, Acpp, A030005E02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56318
HGNC: HGNC:125
Homologene: 55552
Cfap251
Name: cilia and flagella associated protein 251
Synonyms: 4933428F06Rik, 4930415N18Rik, Wdr66
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269701
Homologene: 16964
Klra8
Name: killer cell lectin-like receptor, subfamily A, member 8
Synonyms: Ly49h, Cmv1, Cmv-1, Ly49u129
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16639
Homologene: 110821
Gjc2
Name: gap junction protein, gamma 2
Synonyms: Cx47, B230382L12Rik, Gja12, connexin 47
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 118454
Homologene: 10715
Gsdma2
Name: gasdermin A2
Synonyms: 2210411P14Rik, Gsdml2, 2210009F20Rik, 2210006M16Rik, 2200001G21Rik, Gsdm2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76758
Vmn1r217
Name: vomeronasal 1 receptor 217
Synonyms: V1rh14
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171273
Homologene: 110880
Itga10
Name: integrin, alpha 10
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213119
HGNC: HGNC:6135
Homologene: 2697
Or9k7
Name: olfactory receptor family 9 subfamily K member 7
Synonyms: Olfr827, GA_x6K02T2PULF-11878777-11877809, MOR210-5
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258297
Homologene: 27117
Trim62
Name: tripartite motif-containing 62
Synonyms: Dear1, 6330414G21Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67525
Homologene: 10071
Or5d16
Name: olfactory receptor family 5 subfamily D member 16
Synonyms: GA_x6K02T2Q125-49426894-49425950, MOR174-10, Olfr1155
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258636
Homologene: 133739
Ifitm5
Name: interferon induced transmembrane protein 5
Synonyms: Hrmp1, fragilis4, 1110003J06Rik, Bril
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73835
Homologene: 14210
Tdpoz3
Name: TD and POZ domain containing 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 399674
Homologene: 128308
Vmn2r117
Name: vomeronasal 2, receptor 117
Synonyms: EG619788, V2Rp6
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 619788
Homologene: 86604
Catsperd
Name: cation channel sperm associated auxiliary subunit delta
Synonyms: Gm6095, 4921529N20Rik, 4933402B14Rik, Tmem146
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106757
VEGA: 17
Homologene: 51896
Cfap210
Name: cilia and flagella associated protein 210
Synonyms: 4930578N16Rik, Ccdc173, 4930525K21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75051
Homologene: 18989
Slc10a5
Name: solute carrier family 10 (sodium/bile acid cotransporter family), member 5
Synonyms: LOC241877
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241877
Homologene: 78106
Cibar1
Name: CBY1 interacting BAR domain containing 1
Synonyms: 6720467C03Rik, Fam92a
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68099
Homologene: 12234
Tekt5
Name: tektin 5
Synonyms: 3300001K11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70426
Homologene: 71928
Or10ag2
Name: olfactory receptor family 10 subfamily AG member 2
Synonyms: MOR264-17, GA_x6K02T2Q125-48917235-48918206, Olfr1123
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258347
Homologene: 105187
Zfp72
Name: zinc finger protein 72
Synonyms: Zfp74
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238722
VEGA: 13
Homologene: 108290
Pramel12
Name: PRAME like 12
Synonyms: Pramef8, 4732496O08Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242736
Homologene: 128393
Or2z9
Name: olfactory receptor family 2 subfamily Z member 9
Synonyms: Olfr373, GA_x6K02T2NUPS-231686-232630, MOR282-2, MOR282-1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 258532
Homologene: 17287
Lrat
Name: lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
Synonyms: 1300010A18Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 79235
HGNC: HGNC:6685
Homologene: 3483
Fpr3
Name: formyl peptide receptor 3
Synonyms: Lxa4r, Fprl1, Fpr-rs1, LXA4-R
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14294
Slc37a4
Name: solute carrier family 37 (glucose-6-phosphate transporter), member 4
Synonyms: G6pt1, G6PT
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14385
VEGA: 9
HGNC: HGNC:4061
Homologene: 37482
Gm45861
Name: predicted gene 45861
Type: Gene
Species: Mouse
Chromosome: 8
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 44,059,775 bp
  • T to G, chromosome 1 at 71,576,846 bp
  • A to T, chromosome 2 at 69,781,848 bp
  • A to T, chromosome 2 at 76,881,721 bp
  • A to G, chromosome 2 at 87,418,615 bp
  • A to G, chromosome 2 at 87,942,690 bp
  • A to G, chromosome 3 at 10,335,595 bp
  • G to A, chromosome 3 at 82,903,654 bp
  • A to G, chromosome 3 at 89,152,629 bp
  • T to A, chromosome 3 at 93,826,465 bp
  • A to G, chromosome 3 at 96,662,599 bp
  • T to C, chromosome 4 at 12,168,309 bp
  • A to G, chromosome 4 at 128,884,228 bp
  • T to C, chromosome 4 at 143,417,909 bp
  • G to T, chromosome 4 at 156,177,007 bp
  • A to G, chromosome 5 at 123,287,752 bp
  • T to A, chromosome 5 at 123,500,419 bp
  • T to A, chromosome 6 at 24,604,158 bp
  • A to T, chromosome 6 at 84,192,938 bp
  • C to A, chromosome 6 at 93,697,320 bp
  • T to G, chromosome 6 at 130,125,160 bp
  • T to A, chromosome 7 at 4,469,900 bp
  • T to A, chromosome 7 at 98,467,625 bp
  • A to G, chromosome 7 at 140,949,259 bp
  • G to A, chromosome 7 at 144,655,731 bp
  • T to A, chromosome 8 at 27,527,081 bp
  • T to A, chromosome 8 at 72,100,528 bp
  • G to T, chromosome 8 at 104,236,810 bp
  • A to T, chromosome 9 at 44,400,034 bp
  • G to A, chromosome 9 at 67,392,532 bp
  • T to C, chromosome 9 at 104,300,965 bp
  • A to G, chromosome 9 at 119,609,790 bp
  • C to T, chromosome 10 at 50,909,410 bp
  • A to T, chromosome 10 at 89,645,742 bp
  • T to A, chromosome 10 at 130,210,753 bp
  • A to T, chromosome 11 at 59,177,092 bp
  • C to A, chromosome 11 at 62,329,486 bp
  • T to A, chromosome 11 at 98,652,557 bp
  • G to T, chromosome 11 at 110,115,497 bp
  • G to A, chromosome 11 at 115,850,799 bp
  • G to T, chromosome 12 at 51,764,162 bp
  • G to T, chromosome 12 at 76,064,195 bp
  • T to G, chromosome 13 at 13,743,375 bp
  • T to A, chromosome 13 at 23,113,938 bp
  • T to C, chromosome 13 at 74,371,742 bp
  • T to C, chromosome 13 at 93,091,252 bp
  • A to C, chromosome 14 at 40,913,441 bp
  • T to C, chromosome 16 at 10,358,301 bp
  • A to T, chromosome 16 at 15,628,697 bp
  • T to C, chromosome 16 at 56,204,584 bp
  • A to C, chromosome 17 at 12,270,985 bp
  • T to A, chromosome 17 at 17,971,167 bp
  • C to G, chromosome 17 at 23,479,505 bp
  • T to A, chromosome 17 at 56,650,781 bp
  • T to C, chromosome 17 at 83,766,551 bp
  • T to A, chromosome 18 at 24,108,755 bp
  • T to A, chromosome 18 at 34,827,328 bp
  • A to T, chromosome 18 at 67,675,971 bp
  • A to G, chromosome 18 at 76,860,557 bp
  • T to A, chromosome 19 at 10,596,266 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6909 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045001-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.