Strain Name:
C57BL/6J-MtgxR7332Btlr/Mmmh
Stock Number:
045425-MU
Citation ID:
RRID:MMRRC_045425-MU
Other Names:
R7332 (G1)
Major Collection:

Strain Information

Tomm20
Name: translocase of outer mitochondrial membrane 20
Synonyms: 1810060K07Rik, TOM20
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67952
Homologene: 44649
Gldc
Name: glycine decarboxylase
Synonyms: D19Wsu57e, b2b2679Clo, D030049L12Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 104174
VEGA: 19
HGNC: HGNC:4313
Homologene: 141
Kcna6
Name: potassium voltage-gated channel, shaker-related, subfamily, member 6
Synonyms: MK1.6, Kv1.6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16494
HGNC: HGNC:6225
Homologene: 1684
Rbm47
Name: RNA binding motif protein 47
Synonyms: 9530077J19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 245945
Homologene: 36932
Llgl2
Name: LLGL2 scribble cell polarity complex component
Synonyms: 9130006H11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217325
HGNC: HGNC:6629
Homologene: 3323
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, Phr1, C130061D10Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105689
Homologene: 9005
Wdr59
Name: WD repeat domain 59
Synonyms: 5430401O09Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 319481
Homologene: 38685
Mast4
Name: microtubule associated serine/threonine kinase family member 4
Synonyms: 4930420O11Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 328329
Homologene: 42094
Setx
Name: senataxin
Synonyms: Als4, A930037J23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269254
HGNC: HGNC:445
Homologene: 41003
Ints3
Name: integrator complex subunit 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229543
Homologene: 11309
Rcl1
Name: RNA terminal phosphate cyclase-like 1
Synonyms: 2310040A02Rik, Rnac, RPCL1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 59028
VEGA: 19
Homologene: 4217
Mmp2
Name: matrix metallopeptidase 2
Synonyms: gelatinase A, 72kDa type IV collagenase, GelA, 72kDa gelatinase, Clg4a, MMP-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17390
HGNC: HGNC:7166
Homologene: 3329
Spag5
Name: sperm associated antigen 5
Synonyms: MAP126, D11Bhm180e, Deepest, Astrin, S17, s17, Mastrin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 54141
Homologene: 4718
Zfp68
Name: zinc finger protein 68
Synonyms: Zfp70, KRAZ2, KRAB3, Zfp68
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 24135
Homologene: 56605
Zfp846
Name: zinc finger protein 846
Synonyms: 2210010B09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244721
Homologene: 87243
Csrp1
Name: cysteine and glycine-rich protein 1
Synonyms: CRP1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13007
HGNC: HGNC:2469
Homologene: 37874
Clk1
Name: CDC-like kinase 1
Synonyms: STY, Clk1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12747
HGNC: HGNC:2068
Homologene: 101535
Kirrel1
Name: kirre like nephrin family adhesion molecule 1
Synonyms: Kirrel, Kirrel1, 6720469N11Rik, Neph1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 170643
Homologene: 10089
Sec24b
Name: SEC24 homolog B, COPII coat complex component
Synonyms: SEC24
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99683
Homologene: 55968
Ssh2
Name: slingshot protein phosphatase 2
Synonyms: SSH-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237860
Homologene: 14116
Tctn1
Name: tectonic family member 1
Synonyms: G730031O11Rik, Tect1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 654470
Homologene: 49770
Tmeff2
Name: transmembrane protein with EGF-like and two follistatin-like domains 2
Synonyms: 4832418D20Rik, 7630402F16Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 56363
Homologene: 9417
Pfdn2
Name: prefoldin 2
Synonyms: ESTM27, W48336
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18637
HGNC: HGNC:8867
Homologene: 7887
Spink5
Name: serine peptidase inhibitor, Kazal type 5
Synonyms: LEKT1, 2310065D10Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 72432
Homologene: 4987
Igfbp7
Name: insulin-like growth factor binding protein 7
Synonyms: mac25, AGM, Fstl2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 29817
HGNC: HGNC:5476
Homologene: 1193
Cmya5
Name: cardiomyopathy associated 5
Synonyms: Myospryn, 2310076E21Rik, 2310076E16Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76469
VEGA: 13
Homologene: 137367
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: D12Ertd777e, Cpfl8, dice, 6820443O06Rik, nesprin-2, syne-2, Nesp2g, diminished cone electroretinogram
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 319565
Homologene: 56700
Pik3c2g
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18705
HGNC: HGNC:8973
Homologene: 3362
Zim1
Name: zinc finger, imprinted 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22776
Homologene: 129793
Scn7a
Name: sodium channel, voltage-gated, type VII, alpha
Synonyms: 1110034K09Rik, Scn6a, Nax, Nav2.3, NaG, Nav2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20272
Homologene: 55706
Gsap
Name: gamma-secretase activating protein
Synonyms: Pion, A530088I07Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212167
Homologene: 45504
Sstr1
Name: somatostatin receptor 1
Synonyms: Smstr1, sst1, Smstr-1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20605
Homologene: 820
V1rd19
Name: vomeronasal 1 receptor, D19
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404287
Homologene: 104166
Col5a2
Name: collagen, type V, alpha 2
Synonyms: 1110014L14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12832
HGNC: HGNC:2210
Homologene: 20119
Cfap44
Name: cilia and flagella associated protein 44
Synonyms: 6330444M21Rik, Wdr52, D16Ertd642e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 212517
Homologene: 75085
Vmn2r61
Name: vomeronasal 2, receptor 61
Synonyms: EG637873, Gprc2a-rs2, Casr-rs2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 637873
Homologene: 129683
Naip6
Name: NLR family, apoptosis inhibitory protein 6
Synonyms: Naip-rs4A, Birc1f, Naip-rs4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17952
HGNC: HGNC:7634
Homologene: 113589
Slco3a1
Name: solute carrier organic anion transporter family, member 3a1
Synonyms: Slc21a11, 5830414C08Rik, MJAM, Anr1, OATP-D
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 108116
Homologene: 40862
Rdh1
Name: retinol dehydrogenase 1 (all trans)
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 107605
Homologene: 129514
Cmpk2
Name: cytidine/uridine monophosphate kinase 2
Synonyms: TDKI, Tyki, 1200004E04Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 22169
VEGA: 12
Homologene: 10748
Afap1l2
Name: actin filament associated protein 1-like 2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226250
Homologene: 13057
Csmd2
Name: CUB and Sushi multiple domains 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329942
Homologene: 89034
Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Synonyms: alpha1E, Cav2.3, Cchra1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12290
HGNC: HGNC:1392
Homologene: 20185
Hps1
Name: HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
Synonyms: 6030422N11Rik, Hermansky-Pudlak syndrome 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 192236
HGNC: HGNC:5163
Homologene: 163
Ppip5k1
Name: diphosphoinositol pentakisphosphate kinase 1
Synonyms: Hisppd2a, B430315C20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 327655
Homologene: 49395
Fggy
Name: FGGY carbohydrate kinase domain containing
Synonyms: 2310009E04Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 75578
Homologene: 49535
Coro1b
Name: coronin, actin binding protein 1B
Synonyms: coronin 2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 23789
HGNC: HGNC:2253
Homologene: 40790
Clcnkb
Name: chloride channel, voltage-sensitive Kb
Synonyms: Clcnk1l, Clcnk2, Clck2, ClC-K2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56365
Homologene: 107317
Cdadc1
Name: cytidine and dCMP deaminase domain containing 1
Synonyms: NYD-SP15, 2310010M10Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 71891
VEGA: 14
Homologene: 12794
Tiam2
Name: T cell lymphoma invasion and metastasis 2
Synonyms: 3000002F19Rik, STEF
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 24001
VEGA: 17
Homologene: 40796
Lrrc27
Name: leucine rich repeat containing 27
Synonyms: 1700071K18Rik, 2310044E02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76612
Homologene: 19268
Cyp3a25
Name: cytochrome P450, family 3, subfamily a, polypeptide 25
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56388
Homologene: 135775
Or4g17
Name: olfactory receptor family 4 subfamily G member 17
Synonyms: MOR245-13, GA_x6K02T2Q125-72430580-72431515, Olfr1284
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258379
Homologene: 74059
Gm4952
Name: predicted gene 4952
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240549
Homologene: 72602
Egfl7
Name: EGF-like domain 7
Synonyms: Zneu1, VE-statin, vascular endothelial-statin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 353156
Homologene: 9427
Mas1
Name: MAS1 oncogene
Synonyms: Mas-1, Mas receptor, MasR
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17171
HGNC: HGNC:6899
Homologene: 1782
Zfp40
Name: zinc finger protein 40
Synonyms: NTfin12, Zfp-40
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22700
Homologene: 136312
Srd5a1
Name: steroid 5 alpha-reductase 1
Synonyms: 4930435F02Rik, 0610031P22Rik, Srd5a-1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 78925
Homologene: 37426
Hsbp1l1
Name: heat shock factor binding protein 1-like 1
Synonyms: 1810005K13Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 66255
VEGA: 18
Homologene: 122116
Serpinb5
Name: serine (or cysteine) peptidase inhibitor, clade B, member 5
Synonyms: Maspin, ovalbumin, 1110036M19Rik, Spi7
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20724
HGNC: HGNC:8949
Homologene: 20580
Prss44
Name: serine protease 44
Synonyms: 1700036D21Rik, TESSP4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73336
Homologene: 135977
Vmn1r18
Name: vomeronasal 1 receptor 18
Synonyms: V1rc26
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171199
Homologene: 138094
Atp6v0c
Name: ATPase, H+ transporting, lysosomal V0 subunit C
Synonyms: Atpl-rs1, Atp6c2, Atp6l, H(+)-ATPase (mvp), Atpl, proteolipid, PL16
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 11984
HGNC: HGNC:855
Homologene: 68199
Ucn2
Name: urocortin 2
Synonyms: Urocortin II, Ucn-2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 171530
Homologene: 50048
Pramel51
Name: PRAME like 51
Synonyms: Gm10436
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 100039315
VEGA: 12
Homologene: 103830
Pdf
Name: peptide deformylase (mitochondrial)
Synonyms: 2610019N19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 68023
Homologene: 69354
Zfp729b
Name: zinc finger protein 729b
Synonyms: AA987161
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 100416706
Homologene: 133713
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to G, chromosome 1 at 45,380,165 bp
  • T to C, chromosome 1 at 50,979,440 bp
  • G to A, chromosome 1 at 58,412,694 bp
  • A to T, chromosome 1 at 106,872,361 bp
  • G to T, chromosome 1 at 135,739,411 bp
  • T to C, chromosome 1 at 154,725,801 bp
  • T to C, chromosome 1 at 171,356,594 bp
  • C to A, chromosome 2 at 26,590,713 bp
  • T to C, chromosome 2 at 29,146,626 bp
  • C to T, chromosome 2 at 66,692,554 bp
  • A to G, chromosome 2 at 111,379,393 bp
  • A to T, chromosome 2 at 121,311,969 bp
  • T to C, chromosome 3 at 87,088,398 bp
  • T to C, chromosome 3 at 90,415,512 bp
  • T to C, chromosome 3 at 130,041,393 bp
  • A to T, chromosome 4 at 95,623,482 bp
  • A to G, chromosome 4 at 128,419,567 bp
  • A to T, chromosome 4 at 141,413,932 bp
  • T to A, chromosome 5 at 21,290,121 bp
  • A to G, chromosome 5 at 66,026,214 bp
  • G to A, chromosome 5 at 77,351,956 bp
  • A to T, chromosome 5 at 122,261,484 bp
  • A to G, chromosome 5 at 138,606,568 bp
  • A to G, chromosome 5 at 145,993,007 bp
  • A to G, chromosome 6 at 57,390,518 bp
  • A to G, chromosome 6 at 126,739,329 bp
  • C to A, chromosome 6 at 139,896,255 bp
  • T to C, chromosome 7 at 6,677,353 bp
  • A to T, chromosome 7 at 24,003,318 bp
  • A to G, chromosome 7 at 42,260,110 bp
  • G to A, chromosome 7 at 74,318,484 bp
  • A to G, chromosome 7 at 139,242,745 bp
  • A to G, chromosome 8 at 92,850,152 bp
  • T to C, chromosome 8 at 107,048,541 bp
  • G to A, chromosome 8 at 111,494,354 bp
  • T to C, chromosome 8 at 126,937,153 bp
  • T to G, chromosome 9 at 20,594,225 bp
  • A to G, chromosome 9 at 108,986,464 bp
  • A to T, chromosome 9 at 110,815,462 bp
  • A to G, chromosome 10 at 127,759,885 bp
  • T to A, chromosome 11 at 77,453,523 bp
  • T to A, chromosome 11 at 78,313,379 bp
  • T to C, chromosome 11 at 115,848,299 bp
  • A to T, chromosome 12 at 26,478,062 bp
  • C to T, chromosome 12 at 58,213,386 bp
  • T to A, chromosome 12 at 75,967,755 bp
  • T to C, chromosome 12 at 88,176,417 bp
  • T to C, chromosome 13 at 67,609,636 bp
  • T to C, chromosome 13 at 69,611,054 bp
  • A to G, chromosome 13 at 93,092,553 bp
  • A to G, chromosome 13 at 100,300,701 bp
  • T to A, chromosome 13 at 102,751,424 bp
  • A to G, chromosome 14 at 59,575,764 bp
  • A to G, chromosome 14 at 103,156,453 bp
  • T to A, chromosome 14 at 103,197,357 bp
  • T to A, chromosome 16 at 44,429,828 bp
  • A to G, chromosome 17 at 3,453,369 bp
  • T to C, chromosome 17 at 12,842,219 bp
  • A to T, chromosome 17 at 23,176,181 bp
  • A to C, chromosome 17 at 24,169,224 bp
  • T to C, chromosome 18 at 43,982,250 bp
  • T to C, chromosome 18 at 80,236,823 bp
  • A to G, chromosome 19 at 4,149,357 bp
  • T to A, chromosome 19 at 12,627,009 bp
  • A to T, chromosome 19 at 29,130,696 bp
  • A to T, chromosome 19 at 30,116,526 bp
  • T to C, chromosome 19 at 42,777,912 bp
  • A to G, chromosome 19 at 56,918,121 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7332 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045425-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.