Strain Name:
C57BL/6J-MtgxR7380Btlr/Mmmh
Stock Number:
045462-MU
Citation ID:
RRID:MMRRC_045462-MU
Other Names:
R7380 (G1)
Major Collection:

Strain Information

Pkd1
Name: polycystin 1, transient receptor potential channel interacting
Synonyms: polycystin-1, PC-1, PC1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18763
VEGA: 17
HGNC: HGNC:9008
Homologene: 250
Myo10
Name: myosin X
Synonyms: D15Ertd600e, myosin-X
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17909
HGNC: HGNC:7593
Homologene: 36328
Sema7a
Name: sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
Synonyms: Semal, Semaphorin K1, 2900057C09Rik, CDw108
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20361
VEGA: 9
Homologene: 2678
Ptch2
Name: patched 2
Synonyms: ptc2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19207
HGNC: HGNC:9586
Homologene: 37842
Gpd2
Name: glycerol phosphate dehydrogenase 2, mitochondrial
Synonyms: Gdm1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14571
HGNC: HGNC:4456
Homologene: 352
Snx2
Name: sorting nexin 2
Synonyms: 0610030A03Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67804
VEGA: 18
Homologene: 2332
Plk3
Name: polo like kinase 3
Synonyms: Cnk
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12795
HGNC: HGNC:2154
Homologene: 20865
Dmtn
Name: dematin actin binding protein
Synonyms: Epb4.9, dematin
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 13829
VEGA: 14
HGNC: HGNC:3382
Homologene: 1496
Ddx10
Name: DEAD box helicase 10
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 10, 4632415A01Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77591
VEGA: 9
HGNC: HGNC:2735
Homologene: 20922
Nf1
Name: neurofibromin 1
Synonyms: neurofibromin, Mhdadsk9, Nf-1, Dsk9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Naa15
Name: N(alpha)-acetyltransferase 15, NatA auxiliary subunit
Synonyms: 5730450D16Rik, Narg1, Tbdn-1, tubedown, mNAT1, ASTBDN
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74838
Homologene: 14211
Lrba
Name: LPS-responsive beige-like anchor
Synonyms: Lba, D3Ertd775e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80877
HGNC: HGNC:1742
Homologene: 36205
Kdm5a
Name: lysine demethylase 5A
Synonyms: Jarid1a, RBP2, Rbbp2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 214899
HGNC: HGNC:9886
Homologene: 3419
Ankib1
Name: ankyrin repeat and IBR domain containing 1
Synonyms: 2310061P20Rik, 4631416I11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70797
Homologene: 19076
Rsf1
Name: remodeling and spacing factor 1
Synonyms: 4832420A03Rik, XAP8, Hbxap, C030033M12Rik, p325
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Focad
Name: focadhesin
Synonyms: BC057079
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230393
Homologene: 9842
Fam193b
Name: family with sequence similarity 193, member B
Synonyms: IRIZIO
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 212483
VEGA: 13
Homologene: 130095
Slc8a2
Name: solute carrier family 8 (sodium/calcium exchanger), member 2
Synonyms: Ncx2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 110891
Homologene: 27358
Rad50
Name: RAD50 double strand break repair protein
Synonyms: Rad50l, Mrell
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19360
HGNC: HGNC:9816
Homologene: 38092
Igf2bp3
Name: insulin-like growth factor 2 mRNA binding protein 3
Synonyms: 2610101N11Rik, Koc13, IMP3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 140488
Homologene: 4773
Abcc5
Name: ATP-binding cassette, sub-family C member 5
Synonyms: Mrp5, Abcc5b, 2900011L11Rik, Abcc5a
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 27416
HGNC: HGNC:56
Homologene: 21164
Mllt3
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
Synonyms: 2210011H10Rik, 2610012I03Rik, D4Ertd321e, Af9, 3830408D16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 70122
HGNC: HGNC:7136
Homologene: 37933
Myh14
Name: myosin, heavy polypeptide 14
Synonyms: 2400004E04Rik, NMHC II-C
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71960
Homologene: 23480
Robo3
Name: roundabout guidance receptor 3
Synonyms: Rbig1, Rig-1, Robo3a, Rig1, Robo3b
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19649
Homologene: 32119
Car12
Name: carbonic anhydrase 12
Synonyms: 2310047E01Rik, CA XII
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76459
HGNC: HGNC:1371
Homologene: 20327
Copg1
Name: coatomer protein complex, subunit gamma 1
Synonyms: D6Ertd71e, D6Wsu16e, Copg
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54161
HGNC: HGNC:2236
Homologene: 56745
Nbeal1
Name: neurobeachin like 1
Synonyms: A530083I02Rik, A530050O19Rik, 2310076G13Rik, ALS2CR17
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269198
Homologene: 16453
Lrrc8c
Name: leucine rich repeat containing 8 family, member C
Synonyms: E430036I04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100604
Homologene: 12997
Rapgef3
Name: Rap guanine nucleotide exchange factor (GEF) 3
Synonyms: 9330170P05Rik, Epac1, 2310016P22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223864
Homologene: 21231
Mapk3
Name: mitogen-activated protein kinase 3
Synonyms: Mtap2k, Esrk1, Erk-1, Erk1, Prkm3, p44 MAP kinase, p44erk1, p44mapk
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26417
HGNC: HGNC:6877
Homologene: 55682
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b3491Clo, Mdnah5, b2b1537Clo, b2b1134Clo, Dnahc5, b2b1154Clo, b2b1565Clo
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Dchs1
Name: dachsous cadherin related 1
Synonyms: 3110041P15Rik, C130033F22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233651
Homologene: 2771
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Sstr1
Name: somatostatin receptor 1
Synonyms: Smstr-1, Smstr1, sst1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20605
Homologene: 820
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20192
Homologene: 68151
Casq1
Name: calsequestrin 1
Synonyms: CSQ, sCSQ, CSQ1, CSQ-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12372
HGNC: HGNC:1512
Homologene: 20329
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Wdpcp
Name: WD repeat containing planar cell polarity effector
Synonyms: AV249152, homoloc-13
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216560
Homologene: 9299
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239420
Homologene: 65982
Or6d13
Name: olfactory receptor family 6 subfamily D member 13
Synonyms: GA_x54KRFPKN04-58174409-58175392, Olfr213, MOR119-3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258020
Homologene: 74186
Khdrbs2
Name: KH domain containing, RNA binding, signal transduction associated 2
Synonyms: SLM-1, 6330586C16Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 170771
Homologene: 15772
Clstn3
Name: calsyntenin 3
Synonyms: alcadein-beta, Clstn3b, CSTN3, Cst-3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232370
Homologene: 22836
Cpd
Name: carboxypeptidase D
Synonyms: D830034L15Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12874
HGNC: HGNC:2301
Homologene: 999
BC034090
Name: cDNA sequence BC034090
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 207792
Homologene: 19490
Npr2
Name: natriuretic peptide receptor 2
Synonyms: pwe, cn, guanylyl cyclase-B
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230103
HGNC: HGNC:7944
Homologene: 2970
Tmem94
Name: transmembrane protein 94
Synonyms: 2310067B10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71947
Homologene: 8831
Slc24a1
Name: solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214111
VEGA: 9
Homologene: 3472
Themis2
Name: thymocyte selection associated family member 2
Synonyms: BC013712, ICB-1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230787
Homologene: 21009
Padi2
Name: peptidyl arginine deiminase, type II
Synonyms: Pdi, PAD type II, Pdi2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18600
Homologene: 7214
Ugt2b1
Name: UDP glucuronosyltransferase 2 family, polypeptide B1
Synonyms: 1300012D20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71773
Homologene: 68144
Osgin1
Name: oxidative stress induced growth inhibitor 1
Synonyms: 1700012B18Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71839
Homologene: 16325
Zfp959
Name: zinc finger protein 959
Synonyms: BC011426
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224893
Homologene: 138295
Igfn1
Name: immunoglobulin-like and fibronectin type III domain containing 1
Synonyms: 9830123M21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226438
Homologene: 130054
P4ha1
Name: procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
Synonyms: P4ha
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18451
HGNC: HGNC:8546
Homologene: 30998
Vmn2r91
Name: vomeronasal 2, receptor 91
Synonyms: EG665210
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 665210
Homologene: 115024
Inhca
Name: inhibitor of carbonic anhydrase
Synonyms: mICA, 1300017J02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71775
Homologene: 826
Tmem63c
Name: transmembrane protein 63c
Synonyms: 9330187M14Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217733
Homologene: 33129
Cpb2
Name: carboxypeptidase B2
Synonyms: carboxypeptidase U, TAFI, 1110032P04Rik, CPU, carboxypeptidase R, 4930405E17Rik, CPR, thrombin-activatable fibrinolysis inhibitor
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56373
VEGA: 14
HGNC: HGNC:2300
Homologene: 55610
Trmt10c
Name: tRNA methyltransferase 10C, mitochondrial RNase P subunit
Synonyms: D16Ertd454e, 1300018J16Rik, Rg9mtd1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 52575
Homologene: 9858
Slfn8
Name: schlafen 8
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 276950
Homologene: 45432
Nr1h3
Name: nuclear receptor subfamily 1, group H, member 3
Synonyms: Unr1, LXR alpha
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22259
HGNC: HGNC:7966
Homologene: 21165
Gm1527
Name: predicted gene 1527
Synonyms: LOC385263
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 385263
Homologene: 133976
Far2
Name: fatty acyl CoA reductase 2
Synonyms: Mlstd1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330450
Homologene: 69247
Lmx1a
Name: LIM homeobox transcription factor 1 alpha
Synonyms: shaker short-tail, Lmx1.1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 110648
HGNC: HGNC:6653
Homologene: 24921
Gm57858
Name: gene model 57858
Synonyms: Ccdc144b
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241943
Homologene: 87263
Scart1
Name: scavenger receptor family member expressed on T cells 1
Synonyms: Cd163l1, E430002D04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244233
Homologene: 129778
Rbm44
Name: RNA binding motif protein 44
Synonyms: LOC329207
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329207
Homologene: 66636
Vps52
Name: VPS52 GARP complex subunit
Synonyms: tcl-w5, ARE1, tclw5, D430041K17Rik, Sacm2l
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224705
Homologene: 5756
Prr14
Name: proline rich 14
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233895
Homologene: 11424
Or6c2
Name: olfactory receptor family 6 subfamily C member 2
Synonyms: MOR114-1, GA_x6K02T2PULF-11205096-11206034, Olfr791
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258932
Homologene: 71950
Acads
Name: acyl-Coenzyme A dehydrogenase, short chain
Synonyms: Bcd-1, SCAD, Bcd1, Hdlq8
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11409
HGNC: HGNC:90
Homologene: 20057
Fam162b
Name: family with sequence similarity 162, member B
Synonyms: 9430073N08Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 77296
VEGA: 10
Homologene: 82459
Slc16a13
Name: solute carrier family 16 (monocarboxylic acid transporters), member 13
Synonyms: 1700007D07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69309
Homologene: 71749
Tmem106b
Name: transmembrane protein 106B
Synonyms: 2310036D22Rik, 6430519M21Rik, 5830455K21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71900
Homologene: 56806
Or5ac21
Name: olfactory receptor family 5 subfamily AC member 21
Synonyms: MOR182-5, GA_x54KRFPKG5P-55517445-55518365, Olfr203
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258479
Homologene: 122781
Rab3gap1
Name: RAB3 GTPase activating protein subunit 1
Synonyms: 4732493F09Rik, p130, 1700003B17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226407
Homologene: 45617
1700030J22Rik
Name: RIKEN cDNA 1700030J22 gene
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 69528
Homologene: 51842
Mcee
Name: methylmalonyl CoA epimerase
Synonyms: 1110007A04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73724
Homologene: 13078
Cfap54
Name: cilia and flagella associated protein 54
Synonyms: Gm872, 4930485B16Rik, LOC380653
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 380654
Homologene: 133438
Ring1
Name: ring finger protein 1
Synonyms: Ring1A
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19763
Homologene: 68283
Or1e1d-ps1
Name: olfactory receptor family 1 subfamily E member 1D, pseudogene 1
Synonyms: GA_x6K02T2P1NL-4083149-4084087, Olfr396-ps1, MOR135-19
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258208
Gm12728
Name: predicted gene 12728
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269569
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 32,333,604 bp
  • T to A, chromosome 1 at 60,244,810 bp
  • A to G, chromosome 1 at 91,152,216 bp
  • T to C, chromosome 1 at 127,937,990 bp
  • C to A, chromosome 1 at 135,962,008 bp
  • T to G, chromosome 1 at 155,232,483 bp
  • T to C, chromosome 1 at 167,692,040 bp
  • A to G, chromosome 1 at 172,216,849 bp
  • A to T, chromosome 2 at 57,340,159 bp
  • A to T, chromosome 2 at 91,190,195 bp
  • T to C, chromosome 2 at 112,640,157 bp
  • T to A, chromosome 3 at 28,920,472 bp
  • T to A, chromosome 3 at 36,025,921 bp
  • T to G, chromosome 3 at 51,459,847 bp
  • C to G, chromosome 3 at 86,325,074 bp
  • T to A, chromosome 4 at 43,641,254 bp
  • T to C, chromosome 4 at 87,791,943 bp
  • T to A, chromosome 4 at 88,274,198 bp
  • T to C, chromosome 4 at 105,794,396 bp
  • C to A, chromosome 4 at 117,114,646 bp
  • T to C, chromosome 4 at 117,131,153 bp
  • C to T, chromosome 4 at 132,786,217 bp
  • G to A, chromosome 4 at 140,917,686 bp
  • G to T, chromosome 5 at 3,722,576 bp
  • A to T, chromosome 5 at 86,917,719 bp
  • A to G, chromosome 5 at 105,607,835 bp
  • C to A, chromosome 5 at 115,110,998 bp
  • T to C, chromosome 6 at 13,078,168 bp
  • T to C, chromosome 6 at 49,108,999 bp
  • T to G, chromosome 6 at 87,893,842 bp
  • T to C, chromosome 6 at 116,540,933 bp
  • C to A, chromosome 6 at 120,405,918 bp
  • T to C, chromosome 6 at 124,456,989 bp
  • T to C, chromosome 6 at 148,180,995 bp
  • C to T, chromosome 7 at 16,134,353 bp
  • A to T, chromosome 7 at 44,661,042 bp
  • A to G, chromosome 7 at 64,411,909 bp
  • GGCGG to GGCGGTGGCCGCGG, chromosome 7 at 97,579,915 bp
  • G to T, chromosome 7 at 105,758,628 bp
  • A to T, chromosome 7 at 126,764,795 bp
  • A to T, chromosome 7 at 127,476,442 bp
  • A to T, chromosome 7 at 140,224,877 bp
  • T to C, chromosome 8 at 116,973,637 bp
  • T to A, chromosome 8 at 119,445,431 bp
  • T to C, chromosome 9 at 37,418,556 bp
  • T to A, chromosome 9 at 53,240,486 bp
  • T to C, chromosome 9 at 57,961,564 bp
  • A to G, chromosome 9 at 64,948,533 bp
  • A to G, chromosome 9 at 66,747,663 bp
  • G to A, chromosome 9 at 103,279,481 bp
  • T to A, chromosome 10 at 51,590,476 bp
  • A to G, chromosome 10 at 59,350,451 bp
  • C to A, chromosome 10 at 93,047,978 bp
  • A to T, chromosome 10 at 129,526,661 bp
  • T to A, chromosome 11 at 21,711,585 bp
  • T to C, chromosome 11 at 53,695,396 bp
  • T to C, chromosome 11 at 59,056,914 bp
  • T to C, chromosome 11 at 70,219,279 bp
  • T to A, chromosome 11 at 73,928,187 bp
  • G to A, chromosome 11 at 76,802,325 bp
  • C to T, chromosome 11 at 79,546,276 bp
  • C to T, chromosome 11 at 83,003,740 bp
  • T to C, chromosome 11 at 115,796,145 bp
  • A to T, chromosome 12 at 58,213,280 bp
  • A to G, chromosome 12 at 87,077,948 bp
  • A to C, chromosome 13 at 55,542,799 bp
  • G to A, chromosome 14 at 70,617,328 bp
  • A to T, chromosome 14 at 75,256,009 bp
  • A to T, chromosome 15 at 25,779,620 bp
  • T to A, chromosome 15 at 28,370,378 bp
  • T to A, chromosome 15 at 47,586,965 bp
  • G to T, chromosome 15 at 97,766,791 bp
  • A to T, chromosome 16 at 20,397,034 bp
  • A to T, chromosome 16 at 32,755,366 bp
  • A to T, chromosome 16 at 56,034,256 bp
  • A to G, chromosome 16 at 59,304,028 bp
  • T to A, chromosome 17 at 18,136,576 bp
  • T to A, chromosome 17 at 24,581,642 bp
  • C to A, chromosome 17 at 33,958,309 bp
  • T to C, chromosome 17 at 34,021,720 bp
  • T to A, chromosome 17 at 55,898,551 bp
  • T to C, chromosome 18 at 53,194,568 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7380 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045462-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.