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Strain Name:
C57BL/6J-MtgxR7391Btlr/Mmmh
Stock Number:
045473-MU
Citation ID:
RRID:MMRRC_045473-MU
Other Names:
R7391 (G1)
Major Collection:

Strain Information

B3gnt2
Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
Synonyms: B3Galt6, B3gnt1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 53625
Homologene: 4797
Hdlbp
Name: high density lipoprotein (HDL) binding protein
Synonyms: D1Ertd101e, 1110005P14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 110611
HGNC: HGNC:4857
Homologene: 38035
Virma
Name: vir like m6A methyltransferase associated
Synonyms: 1110037F02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66185
Homologene: 41043
Zfhx3
Name: zinc finger homeobox 3
Synonyms: WBP9, A230102L03Rik, Atbf1, Sci
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Hmmr
Name: hyaluronan mediated motility receptor (RHAMM)
Synonyms: CD168, Rhamm
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15366
HGNC: HGNC:5012
Homologene: 8271
Arhgap32
Name: Rho GTPase activating protein 32
Synonyms: p200RhoGAP, GC-GAP, PX-RICS, 3426406O18Rik, Grit
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 330914
Homologene: 8812
Parn
Name: poly(A)-specific ribonuclease (deadenylation nuclease)
Synonyms: DAN, 1200003I18Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74108
VEGA: 16
HGNC: HGNC:8609
Homologene: 31098
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 66,695,528 bp
  • A to T, chromosome 1 at 93,431,061 bp
  • A to G, chromosome 1 at 130,849,566 bp
  • T to C, chromosome 1 at 178,337,078 bp
  • TCACC to TC, chromosome 1 at 188,962,008 bp
  • A to G, chromosome 2 at 32,712,071 bp
  • T to C, chromosome 2 at 75,980,015 bp
  • T to G, chromosome 2 at 82,990,319 bp
  • T to A, chromosome 2 at 93,730,267 bp
  • A to T, chromosome 2 at 112,780,977 bp
  • C to A, chromosome 2 at 126,553,162 bp
  • T to C, chromosome 2 at 167,105,450 bp
  • A to T, chromosome 3 at 89,609,471 bp
  • A to G, chromosome 3 at 95,529,541 bp
  • T to A, chromosome 3 at 106,164,180 bp
  • A to G, chromosome 4 at 11,508,099 bp
  • A to G, chromosome 4 at 43,216,459 bp
  • C to A, chromosome 4 at 56,781,211 bp
  • T to G, chromosome 4 at 56,781,212 bp
  • A to T, chromosome 4 at 58,145,185 bp
  • A to T, chromosome 4 at 118,934,001 bp
  • A to G, chromosome 4 at 140,937,955 bp
  • T to A, chromosome 4 at 143,572,306 bp
  • T to A, chromosome 5 at 8,559,455 bp
  • T to A, chromosome 5 at 86,237,791 bp
  • C to T, chromosome 5 at 103,540,981 bp
  • C to T, chromosome 5 at 128,988,803 bp
  • T to A, chromosome 5 at 135,570,822 bp
  • T to A, chromosome 6 at 17,096,167 bp
  • T to C, chromosome 6 at 55,679,631 bp
  • T to C, chromosome 6 at 71,131,930 bp
  • C to T, chromosome 6 at 89,976,625 bp
  • A to T, chromosome 6 at 114,238,461 bp
  • T to A, chromosome 7 at 4,344,471 bp
  • A to G, chromosome 7 at 6,316,499 bp
  • C to T, chromosome 7 at 98,131,219 bp
  • T to C, chromosome 7 at 102,713,982 bp
  • T to A, chromosome 7 at 111,043,171 bp
  • A to T, chromosome 7 at 112,320,609 bp
  • A to C, chromosome 8 at 41,210,446 bp
  • G to A, chromosome 8 at 70,289,484 bp
  • A to G, chromosome 8 at 72,662,418 bp
  • G to A, chromosome 8 at 108,947,843 bp
  • C to T, chromosome 9 at 18,639,536 bp
  • C to A, chromosome 9 at 32,181,939 bp
  • G to T, chromosome 9 at 87,248,494 bp
  • T to A, chromosome 9 at 118,050,892 bp
  • T to C, chromosome 9 at 119,795,717 bp
  • A to T, chromosome 10 at 18,646,259 bp
  • G to T, chromosome 10 at 39,087,387 bp
  • T to C, chromosome 10 at 79,911,109 bp
  • A to T, chromosome 10 at 109,703,456 bp
  • A to T, chromosome 11 at 22,836,482 bp
  • G to T, chromosome 11 at 40,707,786 bp
  • A to G, chromosome 11 at 49,148,979 bp
  • T to C, chromosome 11 at 49,552,544 bp
  • A to G, chromosome 11 at 74,085,329 bp
  • A to G, chromosome 11 at 79,515,667 bp
  • A to G, chromosome 11 at 99,627,984 bp
  • A to T, chromosome 11 at 100,135,560 bp
  • T to C, chromosome 12 at 73,545,928 bp
  • A to T, chromosome 13 at 67,749,291 bp
  • T to A, chromosome 13 at 112,962,859 bp
  • T to A, chromosome 15 at 82,618,386 bp
  • A to G, chromosome 15 at 100,784,862 bp
  • C to A, chromosome 16 at 13,668,006 bp
  • T to A, chromosome 16 at 16,914,234 bp
  • T to C, chromosome 17 at 21,398,391 bp
  • T to C, chromosome 17 at 25,846,528 bp
  • G to A, chromosome 17 at 36,869,881 bp
  • A to T, chromosome 17 at 38,131,050 bp
  • T to A, chromosome 18 at 35,212,765 bp
  • C to T, chromosome 18 at 38,202,785 bp
  • T to C, chromosome 18 at 54,897,547 bp
  • T to C, chromosome 19 at 5,050,860 bp
  • T to A, chromosome 19 at 6,228,514 bp
  • C to A, chromosome 19 at 29,627,068 bp
  • T to A, chromosome 19 at 29,627,069 bp
  • A to T, chromosome 19 at 39,307,767 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7391 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045473-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.