Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR7437Btlr/Mmmh
Stock Number:
045513-MU
Citation ID:
RRID:MMRRC_045513-MU
Other Names:
R7437 (G1)
Major Collection:

Strain Information

Cep70
Name: centrosomal protein 70
Synonyms: 6720484E09Rik, C030018L16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68121
Homologene: 11387
Ccna2
Name: cyclin A2
Synonyms: Cyca, Ccn1, Ccn-1, Ccna, CycA2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12428
HGNC: HGNC:1578
Homologene: 55562
Crlf2
Name: cytokine receptor-like factor 2
Synonyms: Ly114, Tslpr, Tpte2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 57914
Homologene: 49476
Dars1
Name: aspartyl-tRNA synthetase 1
Synonyms: 5730439G15Rik, Dars
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226414
HGNC: HGNC:2678
Homologene: 1032
Strn3
Name: striatin, calmodulin binding protein 3
Synonyms: SG2NA
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 94186
VEGA: 12
Homologene: 82078
Ift122
Name: intraflagellar transport 122
Synonyms: C86139, Wdr10, sopb
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 81896
Homologene: 12819
Oga
Name: O-GlcNAcase
Synonyms: Hy5, 5830447M11Rik, 4833427O07Rik, 2810009A20Rik, Mgea5
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 76055
VEGA: 19
HGNC: HGNC:7056
Homologene: 8154
Kcnh5
Name: potassium voltage-gated channel, subfamily H (eag-related), member 5
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238271
VEGA: 12
HGNC: HGNC:6254
Homologene: 15858
Epg5
Name: ectopic P-granules 5 autophagy tethering factor
Synonyms: 5430411K18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 100502841
VEGA: 18
Homologene: 14575
Tap1
Name: transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Synonyms: RING4, PSF-1, MTP1, Tap-1, Ham-1, Ham1, Abcb2, TAP
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21354
HGNC: HGNC:43
Homologene: 495
Nectin2
Name: nectin cell adhesion molecule 2
Synonyms: nectin-2, MPH, Cd112, Pvs, Pvrl2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19294
HGNC: HGNC:9707
Homologene: 86092
Rpp30
Name: ribonuclease P/MRP 30 subunit
Synonyms: TSG15, Rnasep2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 54364
VEGA: 19
Homologene: 38180
Ino80
Name: INO80 complex subunit
Synonyms: 2310079N15Rik, INO80, 4632409L19Rik, Inoc1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68142
Homologene: 75070
Kif24
Name: kinesin family member 24
Synonyms: 4933425J19Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 109242
Homologene: 52346
Ahsa1
Name: AHA1, activator of heat shock protein ATPase 1
Synonyms: p38, Aha1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217737
VEGA: 12
HGNC: HGNC:1189
Homologene: 8106
Txndc12
Name: thioredoxin domain containing 12 (endoplasmic reticulum)
Synonyms: 0610040B21Rik, ERp16
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66073
Homologene: 41074
Atl1
Name: atlastin GTPase 1
Synonyms: AD-FSP, SPG3, FSP1, Spg3a
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 73991
VEGA: 12
Homologene: 9302
Wnt16
Name: wingless-type MMTV integration site family, member 16
Synonyms: E130309I19Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 93735
Homologene: 62175
Abca3
Name: ATP-binding cassette, sub-family A member 3
Synonyms: ABC-C, Abc3, 1810036E22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 27410
HGNC: HGNC:33
Homologene: 37437
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: 9330101J02Rik, Ttc40
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212124
Rundc3a
Name: RUN domain containing 3A
Synonyms: Rpip8, Rap2ip
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 51799
Homologene: 4871
Atp10a
Name: ATPase, class V, type 10A
Synonyms: pfatp, Atp10c
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11982
Homologene: 56461
Akap3
Name: A kinase anchor protein 3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11642
HGNC: HGNC:373
Homologene: 4688
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, 2900022L05Rik, Dnhd3, Dnahc2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Megf10
Name: multiple EGF-like-domains 10
Synonyms: LOC240312, 3000002B06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70417
Homologene: 23771
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Csf1
Name: colony stimulating factor 1 (macrophage)
Synonyms: CSF-1, M-CSF, colony-stimulating factor-1, Csfm, BAP025
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12977
HGNC: HGNC:2432
Homologene: 7282
Samd3
Name: sterile alpha motif domain containing 3
Synonyms: LOC268288
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 268288
VEGA: 10
Homologene: 67991
Pcdhb13
Name: protocadherin beta 13
Synonyms: PcdhbM, Pcdbh6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93884
HGNC: HGNC:8691
Homologene: 10338
Pglyrp3
Name: peptidoglycan recognition protein 3
Synonyms: LOC242100
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242100
Homologene: 71559
Abca8a
Name: ATP-binding cassette, sub-family A member 8a
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217258
HGNC: HGNC:38
Homologene: 131160
C4b
Name: complement C4B (Chido blood group)
Synonyms: Ss, C4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12268
Homologene: 36030
Ngef
Name: neuronal guanine nucleotide exchange factor
Synonyms: ephexin, Tims2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 53972
HGNC: HGNC:7807
Homologene: 75120
Or1e1c
Name: olfactory receptor family 1 subfamily E member 1C
Synonyms: GA_x6K02T2P1NL-3535075-3536028, MOR135-12, Olfr376
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258924
Homologene: 133579
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76645
Homologene: 124481
Zfp959
Name: zinc finger protein 959
Synonyms: BC011426
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224893
Homologene: 138295
Zfp932
Name: zinc finger protein 932
Synonyms: 2310001H12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69504
Homologene: 137770
Fam186a
Name: family with sequence similarity 186, member A
Synonyms: LOC380973, 1700030F18Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72277
Serpinb3c
Name: serine (or cysteine) peptidase inhibitor, clade B, member 3C
Synonyms: 1110001H02Rik, 1110013A16Rik, ovalbumin, Serpinb4, Scca2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381286
Homologene: 131278
Slc9a9
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 9
Synonyms: 5730527A11Rik, Nhe9
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 331004
Homologene: 69753
Rcn2
Name: reticulocalbin 2
Synonyms: taipoxin-associated calcium binding protein 49, TCBP-49
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 26611
HGNC: HGNC:9935
Homologene: 2176
Or5an1b
Name: olfactory receptor family 5 subfamily AN member 1B
Synonyms: GA_x6K02T2RE5P-2658227-2657289, MOR214-6, Olfr1437
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258117
Homologene: 83129
Ccdc186
Name: coiled-coil domain containing 186
Synonyms: Otg1, 1810028B20Rik, A630007B06Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 213993
Homologene: 9963
Kndc1
Name: kinase non-catalytic C-lobe domain (KIND) containing 1
Synonyms: VKIND, very-kind, 2410012C07Rik, B830014K08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76484
Homologene: 45138
Tlcd5
Name: TLC domain containing 5
Synonyms: LOC235300, Tmem136
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235300
VEGA: 9
Homologene: 72560
Pcdhb17
Name: protocadherin beta 17
Synonyms: Pcdhb16, PcdhbQ
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93888
Homologene: 81881
Or10ag56
Name: olfactory receptor family 10 subfamily AG member 56
Synonyms: GA_x6K02T2Q125-48795705-48796673, MOR264-22, Olfr1118-ps, Olfr1118
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 404328
Homologene: 134077
Aebp1
Name: AE binding protein 1
Synonyms: ACLP
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11568
HGNC: HGNC:303
Homologene: 878
Adamtsl2
Name: ADAMTS-like 2
Synonyms: A930008K15Rik, stb
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 77794
Homologene: 8798
H2-M3
Name: histocompatibility 2, M region locus 3
Synonyms: Hmt, H-2M3, R4B2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14991
HGNC: HGNC:4964
Homologene: 133255
Prxl2b
Name: peroxiredoxin like 2B
Synonyms: PM/PGFS, 2810405K02Rik, Fam213b
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66469
Homologene: 11976
Tmem181a
Name: transmembrane protein 181A
Synonyms: 5930418K15Rik, Gpr178, C76977, Tmem181
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 77106
Homologene: 44787
Ebi3
Name: Epstein-Barr virus induced gene 3
Synonyms: IL-27, EBI-3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 50498
VEGA: 17
HGNC: HGNC:3129
Homologene: 4207
Zscan4-ps3
Name: zinc finger and SCAN domain containing 4, pseudogene 3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100043042
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 87,480,605 bp
  • A to T, chromosome 1 at 107,271,714 bp
  • A to G, chromosome 1 at 128,372,204 bp
  • A to G, chromosome 2 at 27,089,709 bp
  • A to T, chromosome 2 at 40,822,645 bp
  • G to T, chromosome 2 at 40,822,646 bp
  • A to G, chromosome 2 at 87,309,343 bp
  • A to G, chromosome 2 at 119,442,586 bp
  • T to C, chromosome 3 at 36,571,090 bp
  • A to G, chromosome 3 at 92,030,678 bp
  • T to C, chromosome 3 at 107,750,756 bp
  • T to C, chromosome 4 at 41,404,687 bp
  • T to C, chromosome 4 at 108,856,171 bp
  • C to A, chromosome 4 at 154,896,596 bp
  • T to C, chromosome 5 at 109,554,973 bp
  • T to A, chromosome 5 at 110,010,014 bp
  • G to A, chromosome 6 at 22,288,561 bp
  • C to T, chromosome 6 at 115,926,302 bp
  • A to T, chromosome 6 at 126,865,655 bp
  • T to C, chromosome 7 at 11,612,936 bp
  • A to T, chromosome 7 at 19,749,268 bp
  • G to A, chromosome 7 at 58,658,540 bp
  • A to T, chromosome 7 at 139,650,837 bp
  • G to A, chromosome 7 at 139,909,043 bp
  • A to G, chromosome 8 at 117,030,682 bp
  • C to T, chromosome 9 at 43,111,785 bp
  • T to C, chromosome 9 at 56,058,069 bp
  • T to C, chromosome 9 at 95,228,941 bp
  • T to C, chromosome 9 at 99,291,529 bp
  • A to T, chromosome 10 at 26,270,106 bp
  • T to A, chromosome 11 at 5,869,757 bp
  • T to C, chromosome 11 at 69,498,627 bp
  • A to G, chromosome 11 at 73,375,018 bp
  • A to G, chromosome 11 at 102,398,404 bp
  • A to G, chromosome 11 at 110,050,964 bp
  • A to T, chromosome 12 at 51,610,163 bp
  • A to G, chromosome 12 at 69,931,622 bp
  • C to T, chromosome 12 at 75,137,643 bp
  • A to G, chromosome 12 at 87,268,156 bp
  • A to T, chromosome 15 at 99,942,894 bp
  • A to G, chromosome 17 at 6,303,265 bp
  • A to T, chromosome 17 at 24,400,498 bp
  • G to A, chromosome 17 at 34,190,642 bp
  • T to C, chromosome 17 at 34,734,733 bp
  • T to C, chromosome 17 at 37,272,678 bp
  • G to T, chromosome 17 at 55,898,334 bp
  • T to A, chromosome 17 at 55,954,410 bp
  • T to C, chromosome 18 at 37,444,675 bp
  • A to G, chromosome 18 at 37,486,092 bp
  • G to C, chromosome 18 at 57,262,131 bp
  • A to G, chromosome 18 at 78,023,278 bp
  • T to C, chromosome 19 at 12,322,108 bp
  • A to G, chromosome 19 at 36,104,438 bp
  • A to T, chromosome 19 at 45,778,607 bp
  • T to C, chromosome 19 at 56,806,997 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7437 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045513-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.