Strain Name:
C57BL/6J-MtgxR7656Btlr/Mmmh
Stock Number:
045732-MU
Citation ID:
RRID:MMRRC_045732-MU
Other Names:
R7656 (G1)
Major Collection:

Strain Information

Vcan
Name: versican
Synonyms: DPEAAE, 5430420N07Rik, Cspg2, hdf, heart defect, PG-M
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 13003
HGNC: HGNC:2464
Homologene: 3228
Prmt1
Name: protein arginine N-methyltransferase 1
Synonyms: Hrmt1l2, 6720434D09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15469
HGNC: HGNC:5187
Homologene: 21477
Rapgef6
Name: Rap guanine nucleotide exchange factor (GEF) 6
Synonyms: PDZ-GEF2, C030018K18Rik, Pdzgef2, RA-GEF-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192786
Homologene: 22968
Luc7l2
Name: LUC7-like 2 (S. cerevisiae)
Synonyms: CGI-59, 4930471C18Rik, CGI-74
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 192196
Homologene: 56737
Mtbp
Name: Mdm2, transformed 3T3 cell double minute p53 binding protein
Synonyms: MDM2BP
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105837
HGNC: HGNC:7417
Homologene: 11102
Trrap
Name: transformation/transcription domain-associated protein
Synonyms: transactivation/transformation-domain associated protein
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100683
Homologene: 39246
Mms19
Name: MMS19 cytosolic iron-sulfur assembly component
Synonyms: C86341, Mms19l, 2610042O15Rik, Mms19
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72199
Homologene: 41480
Mdc1
Name: mediator of DNA damage checkpoint 1
Synonyms: NFBD1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240087
Homologene: 67092
Brpf1
Name: bromodomain and PHD finger containing, 1
Synonyms: 4833438B11Rik, 4930540D11Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78783
Homologene: 31251
Orc3
Name: origin recognition complex, subunit 3
Synonyms: Orc3l
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 50793
HGNC: HGNC:8489
Homologene: 8225
Ncapd3
Name: non-SMC condensin II complex, subunit D3
Synonyms: 2810487N22Rik, B130055D15Rik, 4632407J06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 78658
VEGA: 9
Homologene: 41021
Rab3ip
Name: RAB3A interacting protein
Synonyms: Rabin3, SSX2 interacting protein, Gtpat12
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216363
VEGA: 10
Homologene: 32340
T2
Name: brachyury 2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21331
Homologene: 86977
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, LOC381341, Dnahc7a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 627872
Homologene: 41287
Mef2a
Name: myocyte enhancer factor 2A
Synonyms: A430079H05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17258
HGNC: HGNC:6993
Homologene: 4080
Spag9
Name: sperm associated antigen 9
Synonyms: JLP, syd1, 4733401I23Rik, JIP4, Mapk8ip4, 3110018C07Rik, 4831406C20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70834
Homologene: 2954
Prox1
Name: prospero homeobox 1
Synonyms: A230003G05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19130
HGNC: HGNC:9459
Homologene: 2069
Trpm4
Name: transient receptor potential cation channel, subfamily M, member 4
Synonyms: 1110030C19Rik, TRPM4B, LTRPC4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 68667
Homologene: 23033
Chsy1
Name: chondroitin sulfate synthase 1
Synonyms: skt
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269941
Homologene: 8950
Tbc1d19
Name: TBC1 domain family, member 19
Synonyms: 2810453K03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67249
Homologene: 10130
Pcdhb16
Name: protocadherin beta 16
Synonyms: PcdhbP, Pcdhb8
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93887
Homologene: 99843
Rapgef3
Name: Rap guanine nucleotide exchange factor (GEF) 3
Synonyms: 2310016P22Rik, 9330170P05Rik, Epac1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223864
Homologene: 21231
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Ptpn13
Name: protein tyrosine phosphatase, non-receptor type 13
Synonyms: PTP-BL, PTPL1, Ptpri
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19249
HGNC: HGNC:9646
Homologene: 7909
Efhc1
Name: EF-hand domain (C-terminal) containing 1
Synonyms: myoclonin1, mRib72-1, 1700029F22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71877
Homologene: 10003
Agbl1
Name: ATP/GTP binding protein-like 1
Synonyms: Nna1-l1, EG244071, Ccp4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244071
Homologene: 17552
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Hdhc3, HL19, LOC380889, Dnahc7l, DLP12, Dnahc12, 4921531P07Rik, DHC3, HL-19
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Tmem116
Name: transmembrane protein 116
Synonyms: 4930406A18Rik, 4930513P12Rik, C030022K24Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77462
Homologene: 12676
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Krtcap3
Name: keratinocyte associated protein 3
Synonyms: 2010001C09Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69815
Homologene: 12332
Cd244a
Name: CD244 molecule A
Synonyms: C9.1, Cd244, 2B4, Nmrk, F730046O15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18106
Homologene: 9493
Ltf
Name: lactotransferrin
Synonyms: lactoferrin, Lf
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17002
HGNC: HGNC:6720
Homologene: 1754
Gm19410
Name: predicted gene, 19410
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 100502846
Homologene: 132117
Col14a1
Name: collagen, type XIV, alpha 1
Synonyms: 5730412L22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12818
HGNC: HGNC:2191
Homologene: 18741
Camk2g
Name: calcium/calmodulin-dependent protein kinase II gamma
Synonyms: 5930429P18Rik, CaMK II, Camkg, Ca2+/calmodulin-dependent protein kinase II
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12325
VEGA: 14
HGNC: HGNC:1463
Homologene: 15596
Bmal2
Name: basic helix-loop-helix ARNT like 2
Synonyms: bHLHe6, MOP9, 4632430A05Rik, Arntl2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 272322
Homologene: 10609
Grm5
Name: glutamate receptor, metabotropic 5
Synonyms: 6430542K11Rik, Glu5R, mGluR5, Gprc1e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 108071
HGNC: HGNC:4597
Homologene: 37354
Thbd
Name: thrombomodulin
Synonyms: TM, CD141
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21824
Homologene: 308
Rtl1
Name: retrotransposon Gaglike 1
Synonyms: Mart1, Mar, Mor1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 353326
VEGA: 12
Homologene: 120261
Atrnl1
Name: attractin like 1
Synonyms: Alp
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226255
VEGA: 19
Homologene: 45809
Nin
Name: ninein
Synonyms: 3110068G20Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18080
Homologene: 40632
Glp1r
Name: glucagon-like peptide 1 receptor
Synonyms: GLP1Rc, GLP-1R
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14652
VEGA: 17
HGNC: HGNC:4324
Homologene: 1558
Col6a2
Name: collagen, type VI, alpha 2
Synonyms: Col6a-2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12834
HGNC: HGNC:2212
Homologene: 1392
Sgsm2
Name: small G protein signaling modulator 2
Synonyms: D630003G22Rik, Rutbc1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 97761
Homologene: 14780
Ppp2r3a
Name: protein phosphatase 2, regulatory subunit B'', alpha
Synonyms: 3222402P14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235542
HGNC: HGNC:9307
Homologene: 20595
Rnf180
Name: ring finger protein 180
Synonyms: 3110001E11Rik, Rines
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 71816
VEGA: 13
Homologene: 18677
Ccdc33
Name: coiled-coil domain containing 33
Synonyms: 4930535E21Rik, LOC382077
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382077
Homologene: 19641
Or5b123
Name: olfactory receptor family 5 subfamily B member 123
Synonyms: GA_x6K02T2RE5P-3951719-3952666, Olfr1487, MOR202-18
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258629
Homologene: 110492
Phkg2
Name: phosphorylase kinase, gamma 2 (testis)
Synonyms: 1500017I02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 68961
HGNC: HGNC:8931
Homologene: 47915
Xrra1
Name: X-ray radiation resistance associated 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 446101
Homologene: 19547
Plekhd1
Name: pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
Synonyms: 3830431G21Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217682
Homologene: 15090
Acot2
Name: acyl-CoA thioesterase 2
Synonyms: Mte1, MTE-I
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 171210
Homologene: 25661
Tmem25
Name: transmembrane protein 25
Synonyms: 0610039J01Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71687
Homologene: 12403
Spata31e3
Name: spermatogenesis associated 31 subfamily E member 3
Synonyms: LOC380882, Gm906
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 380882
VEGA: 13
Homologene: 134512
Oxct2b
Name: 3-oxoacid CoA transferase 2B
Synonyms: Scot-t2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 353371
Homologene: 137359
Slc26a9
Name: solute carrier family 26, member 9
Synonyms: anion transporter/exchanger-9, E030002L01Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 320718
Homologene: 14179
Saxo2
Name: stabilizer of axonemal microtubules 2
Synonyms: Fam154b, 1700129I04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330577
Homologene: 25135
Prl3d1
Name: prolactin family 3, subfamily d, member 1
Synonyms: PL-Ia, Csh1, Pl-1, Pl1, prolactin-like 2, placental lactogen 1, mPL-I
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 18775
Homologene: 137215
Smoc1
Name: SPARC related modular calcium binding 1
Synonyms: SPARC-related protein, 2600002F22Rik, SRG
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 64075
Homologene: 56943
Ghdc
Name: GH3 domain containing
Synonyms: D11Lgp1e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 80860
Homologene: 32760
BC031181
Name: cDNA sequence BC031181
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 407819
VEGA: 18
Homologene: 74274
Gm15922
Name: predicted gene 15922
Type: Gene
Species: Mouse
Chromosome: 7
Or10z1
Name: olfactory receptor family 10 subfamily Z member 1
Synonyms: GA_x6K02T2P20D-20891507-20892448, MOR267-6, Olfr419
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258710
Homologene: 72017
Rpl3l
Name: ribosomal protein L3-like
Synonyms: 1110057H16Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66211
Homologene: 68434
Abitram
Name: actin binding transcription modulator
Synonyms: Fam206a, simiate, BC026590
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230234
HGNC: HGNC:1364
Homologene: 56788
Mitd1
Name: MIT, microtubule interacting and transport, domain containing 1
Synonyms: 1500032H18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 69028
Homologene: 14787
Selenoh
Name: selenoprotein H
Synonyms: SelH, 2700094K13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72657
Homologene: 86009
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 20,961,057 bp
  • T to A, chromosome 1 at 37,885,275 bp
  • T to C, chromosome 1 at 53,496,005 bp
  • T to A, chromosome 1 at 131,763,244 bp
  • T to A, chromosome 1 at 171,577,255 bp
  • T to A, chromosome 1 at 174,250,218 bp
  • A to G, chromosome 1 at 190,162,221 bp
  • A to T, chromosome 2 at 76,728,316 bp
  • A to G, chromosome 2 at 82,977,542 bp
  • G to T, chromosome 2 at 84,670,380 bp
  • A to G, chromosome 2 at 148,407,420 bp
  • G to T, chromosome 4 at 34,587,032 bp
  • A to G, chromosome 4 at 56,804,218 bp
  • G to A, chromosome 4 at 123,117,757 bp
  • A to G, chromosome 5 at 31,252,560 bp
  • A to G, chromosome 5 at 53,897,035 bp
  • T to A, chromosome 5 at 103,540,983 bp
  • A to G, chromosome 5 at 121,452,189 bp
  • G to T, chromosome 5 at 144,842,612 bp
  • A to G, chromosome 6 at 38,603,464 bp
  • A to T, chromosome 6 at 113,314,874 bp
  • A to G, chromosome 6 at 146,806,442 bp
  • T to C, chromosome 7 at 3,739,282 bp
  • A to T, chromosome 7 at 44,984,128 bp
  • C to T, chromosome 7 at 45,321,809 bp
  • G to T, chromosome 7 at 66,171,030 bp
  • G to A, chromosome 7 at 67,295,394 bp
  • A to G, chromosome 7 at 76,409,332 bp
  • A to G, chromosome 7 at 82,635,351 bp
  • T to G, chromosome 7 at 88,130,251 bp
  • T to A, chromosome 7 at 99,910,982 bp
  • G to A, chromosome 7 at 127,582,902 bp
  • A to T, chromosome 8 at 35,809,099 bp
  • T to A, chromosome 9 at 27,055,505 bp
  • C to T, chromosome 9 at 44,798,343 bp
  • T to A, chromosome 9 at 58,118,465 bp
  • A to T, chromosome 9 at 101,211,712 bp
  • A to T, chromosome 9 at 111,024,394 bp
  • G to T, chromosome 10 at 76,607,756 bp
  • A to G, chromosome 10 at 116,914,139 bp
  • C to T, chromosome 11 at 54,694,453 bp
  • A to G, chromosome 11 at 74,865,497 bp
  • A to C, chromosome 11 at 93,996,563 bp
  • C to T, chromosome 11 at 100,769,667 bp
  • G to A, chromosome 12 at 70,042,768 bp
  • A to G, chromosome 12 at 80,722,160 bp
  • A to T, chromosome 12 at 81,105,908 bp
  • A to G, chromosome 12 at 83,992,917 bp
  • T to C, chromosome 12 at 109,591,008 bp
  • T to C, chromosome 13 at 27,100,035 bp
  • T to G, chromosome 13 at 50,247,086 bp
  • C to T, chromosome 13 at 89,685,114 bp
  • T to C, chromosome 13 at 105,167,588 bp
  • T to G, chromosome 14 at 20,739,342 bp
  • G to T, chromosome 14 at 26,859,316 bp
  • A to G, chromosome 15 at 55,362,450 bp
  • G to T, chromosome 15 at 55,609,526 bp
  • T to C, chromosome 15 at 97,761,209 bp
  • T to A, chromosome 17 at 8,418,215 bp
  • T to C, chromosome 17 at 24,730,986 bp
  • T to C, chromosome 17 at 30,930,598 bp
  • T to G, chromosome 17 at 35,850,881 bp
  • A to T, chromosome 18 at 37,479,405 bp
  • A to T, chromosome 18 at 75,009,335 bp
  • A to T, chromosome 19 at 13,619,833 bp
  • A to G, chromosome 19 at 41,944,572 bp
  • C to A, chromosome 19 at 57,611,379 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7656 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045732-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.