Strain Name:
C57BL/6J-MtgxR7796Btlr/Mmmh
Stock Number:
045852-MU
Citation ID:
RRID:MMRRC_045852-MU
Other Names:
R7796 (G1)
Major Collection:

Strain Information

Nr2f2
Name: nuclear receptor subfamily 2, group F, member 2
Synonyms: ARP-1, 9430015G03Rik, Aporp1, COUP-TFII, EAR3, COUP-TF2, Tcfcoup2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11819
HGNC: HGNC:7976
Homologene: 7628
Epb41l2
Name: erythrocyte membrane protein band 4.1 like 2
Synonyms: D10Ertd398e, 4.1G, Epb4.1l2, NBL2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13822
VEGA: 10
HGNC: HGNC:3379
Homologene: 37478
Rps23rg1
Name: ribosomal protein S23, retrogene 1
Synonyms: C330021F23Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 546049
Homologene: 134322
Zdbf2
Name: zinc finger, DBF-type containing 2
Synonyms: 9330107J05Rik, 4930431J08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 73884
Homologene: 52868
Ybx3
Name: Y box protein 3
Synonyms: oxyR, dbpA, MSY3, Yb2, Dpba, Csda, MSY4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56449
HGNC: HGNC:2428
Homologene: 2708
Ociad1
Name: OCIA domain containing 1
Synonyms: TPA018, Imi2, 6030432N09Rik, expressed during mesenchymal induction 2, Emi2, Asrij, B230209J16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68095
Homologene: 9866
Patj
Name: PATJ, crumbs cell polarity complex component
Synonyms: Cipp, Inadl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12695
Homologene: 72199
Tasp1
Name: taspase, threonine aspartase 1
Synonyms: 4930485D02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75812
Homologene: 9795
Kdm5a
Name: lysine demethylase 5A
Synonyms: Jarid1a, RBP2, Rbbp2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 214899
HGNC: HGNC:9886
Homologene: 3419
Sulf1
Name: sulfatase 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240725
Homologene: 49408
Arap2
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms: Centd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212285
Homologene: 9064
Mki67
Name: antigen identified by monoclonal antibody Ki 67
Synonyms: Ki67, Ki-67, D630048A14Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17345
HGNC: HGNC:7107
Homologene: 1814
Safb2
Name: scaffold attachment factor B2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224902
Homologene: 35210
Tcf4
Name: transcription factor 4
Synonyms: SEF2-1, 5730422P05Rik, E2.2, TFE, E2-2, bHLHb19, SEF-2, ASP-I2, ITF-2b, ME2, MITF-2A, MITF-2B, ITF-2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 21413
Homologene: 2407
Dennd1b
Name: DENN domain containing 1B
Synonyms: 4930467M19Rik, 4632404N19Rik, F730008N07Rik, 6820401H01Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329260
Homologene: 11739
Fndc3b
Name: fibronectin type III domain containing 3B
Synonyms: 1600019O04Rik, fad104
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72007
Homologene: 11244
A630089N07Rik
Name: RIKEN cDNA A630089N07 gene
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 320586
VEGA: 16
Gprc5c
Name: G protein-coupled receptor, family C, group 5, member C
Synonyms: 3200002M13Rik, 1110028I06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70355
Homologene: 11099
Zfp369
Name: zinc finger protein 369
Synonyms: D230020H11Rik, NRIF2, B930030B22Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 170936
Homologene: 129707
Map2
Name: microtubule-associated protein 2
Synonyms: repro4, G1-397-34, Mtap2, MAP-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Zfp54
Name: zinc finger protein 54
Synonyms: clone 18, Zfp-54, Zfp76, KRAB10
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22712
Homologene: 129791
Dync1li2
Name: dynein, cytoplasmic 1 light intermediate chain 2
Synonyms: Dnclic2, Dlic2, LIC2, Dncli2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234663
HGNC: HGNC:2966
Homologene: 4474
Sptbn2
Name: spectrin beta, non-erythrocytic 2
Synonyms: Spnb3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20743
VEGA: 19
Homologene: 48482
Metap1d
Name: methionyl aminopeptidase type 1D (mitochondrial)
Synonyms: 3110033D18Rik, Metapl1, 2310066F24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66559
Homologene: 11987
Smg5
Name: SMG5 nonsense mediated mRNA decay factor
Synonyms: Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229512
Homologene: 9095
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: LOC224126, 2210407G14Rik, E530005C20Rik, Hapip
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Skic2
Name: SKI2 subunit of superkiller complex
Synonyms: Skiv2l, 4930534J06Rik, Ski2w
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 108077
Homologene: 123971
Rpgrip1l
Name: Rpgrip1-like
Synonyms: Nphp8, Ftm, 1700047E16Rik, fantom
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244585
Homologene: 18296
Ttn
Name: titin
Synonyms: mdm, D830007G01Rik, shru, 1100001C23Rik, D330041I19Rik, 2310057K23Rik, 2310036G12Rik, 2310074I15Rik, L56, connectin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Kidins220
Name: kinase D-interacting substrate 220
Synonyms: 3110039L19Rik, C330002I19Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 77480
VEGA: 12
Homologene: 14254
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Gm4847
Name: predicted gene 4847
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226604
Homologene: 101040
Unc80
Name: unc-80, NALCN activator
Synonyms: C030018G13Rik, C230061B10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329178
Homologene: 122243
Megf10
Name: multiple EGF-like-domains 10
Synonyms: LOC240312, 3000002B06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70417
Homologene: 23771
Klhl5
Name: kelch-like 5
Synonyms: 1300013C10Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71778
HGNC: HGNC:6356
Homologene: 56736
Cep85l
Name: centrosomal protein 85-like
Synonyms: Gm9766
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 100038725
VEGA: 10
Homologene: 52598
Lipo3
Name: lipase, member O3
Synonyms: Lipo1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 381236
Homologene: 103863
Pramel22
Name: PRAME like 22
Synonyms: Gm13088
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 277668
Homologene: 129883
Krt87
Name: keratin 87
Synonyms: Krt2-25, Krt83
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 406219
VEGA: 15
Homologene: 133804
Pcdhb2
Name: protocadherin beta 2
Synonyms: PcdhbB
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93873
HGNC: HGNC:8687
Homologene: 69266
Krt17
Name: keratin 17
Synonyms: K17, Krt1-17
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16667
HGNC: HGNC:6427
Homologene: 363
Miip
Name: migration and invasion inhibitory protein
Synonyms: D4Wsu114e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 28010
Homologene: 15879
Agbl4
Name: ATP/GTP binding protein-like 4
Synonyms: 4931433A01Rik, 4930578N11Rik, Ccp6
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 78933
Homologene: 84880
Pla2g6
Name: phospholipase A2, group VI
Synonyms: iPLA2beta, iPLA2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 53357
HGNC: HGNC:9039
Homologene: 2635
Fam50b
Name: family with sequence similarity 50, member B
Synonyms: XAP-5-like, D0H6S2654E, X5L
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 108161
VEGA: 13
Homologene: 101669
Nrsn2
Name: neurensin 2
Synonyms: Neurensin-2, LOC228777
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228777
Homologene: 11802
Acot2
Name: acyl-CoA thioesterase 2
Synonyms: Mte1, MTE-I
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 171210
Homologene: 25661
Or13p5
Name: olfactory receptor family 13 subfamily P member 5
Synonyms: MOR258-2, Olfr1339, GA_x6K02T2QD9B-18815145-18814198
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 258851
Homologene: 27280
Or4a39
Name: olfactory receptor family 4subfamily A member 39
Synonyms: MOR231-11, GA_x6K02T2Q125-50849945-50848998, Olfr1238
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258786
Homologene: 128093
Yipf7
Name: Yip1 domain family, member 7
Synonyms: Yip1b, 2310016N21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75581
Homologene: 69367
Zfp971
Name: zinc finger protein 971
Synonyms: Etohi1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 626848
Homologene: 134324
Pxdc1
Name: PX domain containing 1
Synonyms: 1300014I06Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66895
Homologene: 12051
Gm3159
Name: predicted gene 3159
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100041139
Homologene: 115686
Krtap4-26
Name: keratin associated protein 4-26
Synonyms: Gm11564
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 670496
Tas1r1
Name: taste receptor, type 1, member 1
Synonyms: T1R1, TR1, Gpr70, T1r1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 110326
Homologene: 12888
Dpf1
Name: double PHD fingers 1
Synonyms: neuro-d4, Neud4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 29861
Homologene: 3415
Gm32742
Name: predicted gene, 32742
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102635385
Homologene: 132734
Trav14n-3
Name: T cell receptor alpha variable 14N-3
Synonyms: X76971, 100043308
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100043308
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 12,858,820 bp
  • G to A, chromosome 1 at 63,303,424 bp
  • A to G, chromosome 1 at 66,416,495 bp
  • A to G, chromosome 1 at 66,503,714 bp
  • G to A, chromosome 1 at 139,062,873 bp
  • G to A, chromosome 1 at 166,642,250 bp
  • T to A, chromosome 2 at 71,512,162 bp
  • T to C, chromosome 2 at 76,834,878 bp
  • T to A, chromosome 2 at 89,406,813 bp
  • T to C, chromosome 2 at 140,008,785 bp
  • T to A, chromosome 2 at 152,376,551 bp
  • A to G, chromosome 2 at 178,031,610 bp
  • G to A, chromosome 3 at 27,461,743 bp
  • A to T, chromosome 3 at 88,349,432 bp
  • A to T, chromosome 4 at 98,546,983 bp
  • G to T, chromosome 4 at 110,660,968 bp
  • T to A, chromosome 4 at 118,734,685 bp
  • T to A, chromosome 4 at 143,654,157 bp
  • C to T, chromosome 4 at 147,862,918 bp
  • A to G, chromosome 4 at 152,034,755 bp
  • A to G, chromosome 5 at 62,730,762 bp
  • T to C, chromosome 5 at 65,164,622 bp
  • T to C, chromosome 5 at 69,527,253 bp
  • C to T, chromosome 5 at 73,294,947 bp
  • T to C, chromosome 6 at 120,390,763 bp
  • T to C, chromosome 6 at 131,368,516 bp
  • C to G, chromosome 7 at 29,311,681 bp
  • A to G, chromosome 7 at 70,358,153 bp
  • A to G, chromosome 7 at 135,698,194 bp
  • T to C, chromosome 8 at 3,584,160 bp
  • A to G, chromosome 8 at 91,270,237 bp
  • T to A, chromosome 8 at 104,430,549 bp
  • A to G, chromosome 9 at 51,159,823 bp
  • T to C, chromosome 9 at 79,678,551 bp
  • A to G, chromosome 10 at 25,443,829 bp
  • A to C, chromosome 10 at 53,281,401 bp
  • A to G, chromosome 11 at 99,815,598 bp
  • A to G, chromosome 11 at 100,260,872 bp
  • A to T, chromosome 11 at 114,864,532 bp
  • T to C, chromosome 12 at 24,982,351 bp
  • T to A, chromosome 12 at 83,988,483 bp
  • T to A, chromosome 13 at 34,652,371 bp
  • G to A, chromosome 13 at 34,747,101 bp
  • A to G, chromosome 13 at 65,296,215 bp
  • A to G, chromosome 14 at 4,400,560 bp
  • T to A, chromosome 14 at 53,370,370 bp
  • T to C, chromosome 15 at 79,317,825 bp
  • A to G, chromosome 15 at 101,485,984 bp
  • A to T, chromosome 16 at 34,187,484 bp
  • T to A, chromosome 16 at 98,065,824 bp
  • A to G, chromosome 17 at 21,434,720 bp
  • C to T, chromosome 17 at 34,844,418 bp
  • T to C, chromosome 17 at 56,566,327 bp
  • A to G, chromosome 18 at 37,295,393 bp
  • C to A, chromosome 18 at 57,277,659 bp
  • T to A, chromosome 18 at 69,564,069 bp
  • C to G, chromosome 19 at 4,749,012 bp
  • T to C, chromosome 19 at 33,782,234 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7796 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045852-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.